This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Decamethoxine
- DrugBank Accession Number
- DB13705
- Background
Not Available
- Type
- Small Molecule
- Groups
- Experimental
- Structure
Structure for Decamethoxine (DB13705)
- Weight
- Average: 693.92
Monoisotopic: 692.5025643 - Chemical Formula
- C38H74Cl2N2O4
- Synonyms
- Decamethoxin
- External IDs
- MM-692
Pharmacology
- Indication
Not Available
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Avoid life-threatening adverse drug eventsImprove clinical decision support with information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events & improve clinical decision support.- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates.Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Drug Interaction Integrate drug-drug
interactions in your softwareAcenocoumarol The risk or severity of bleeding can be increased when Decamethoxine is combined with Acenocoumarol. Ambroxol The risk or severity of methemoglobinemia can be increased when Decamethoxine is combined with Ambroxol. Articaine The risk or severity of methemoglobinemia can be increased when Decamethoxine is combined with Articaine. BCG vaccine The therapeutic efficacy of BCG vaccine can be decreased when used in combination with Decamethoxine. Benzocaine The risk or severity of methemoglobinemia can be increased when Decamethoxine is combined with Benzocaine. Benzyl alcohol The risk or severity of methemoglobinemia can be increased when Decamethoxine is combined with Benzyl alcohol. Bupivacaine The risk or severity of methemoglobinemia can be increased when Decamethoxine is combined with Bupivacaine. Butacaine The risk or severity of methemoglobinemia can be increased when Decamethoxine is combined with Butacaine. Butamben The risk or severity of methemoglobinemia can be increased when Decamethoxine is combined with Butamben. Capsaicin The risk or severity of methemoglobinemia can be increased when Decamethoxine is combined with Capsaicin. 
Identify potential medication risksEasily compare up to 40 drugs with our drug interaction checker.Get severity rating, description, and management advice.Learn more - Food Interactions
- Not Available
Categories
- ATC Codes
- D08AJ10 — Decamethoxine
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 81I73K1HKN
- CAS number
- 38146-42-8
- InChI Key
- LRQIWRXCHWNNEA-MWZFJMJKSA-L
- InChI
- InChI=1S/C38H74N2O4.2ClH/c1-29(2)33-21-19-31(5)25-35(33)43-37(41)27-39(7,8)23-17-15-13-11-12-14-16-18-24-40(9,10)28-38(42)44-36-26-32(6)20-22-34(36)30(3)4;;/h29-36H,11-28H2,1-10H3;2*1H/q+2;;/p-2/t31-,32-,33+,34+,35-,36-;;/m1../s1
- IUPAC Name
- {10-[dimethyl(2-{[(1R,2S,5R)-5-methyl-2-(propan-2-yl)cyclohexyl]oxy}-2-oxoethyl)azaniumyl]decyl}dimethyl(2-{[(1R,2S,5R)-5-methyl-2-(propan-2-yl)cyclohexyl]oxy}-2-oxoethyl)azanium dichloride
- SMILES
- [Cl-].[Cl-].CC(C)[C@@H]1CC[C@@H](C)C[C@H]1OC(=O)C[N+](C)(C)CCCCCCCCCC[N+](C)(C)CC(=O)O[C@@H]1C[C@H](C)CC[C@H]1C(C)C
References
- General References
- Not Available
- External Links
- ChemSpider
- 52083646
Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 3.1e-06 mg/mL ALOGPS logP 3.06 ALOGPS logP 0.74 Chemaxon logS -8.4 ALOGPS pKa (Strongest Basic) -7.5 Chemaxon Physiological Charge 2 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 52.6 Å2 Chemaxon Rotatable Bond Count 21 Chemaxon Refractivity 207.03 m3·mol-1 Chemaxon Polarizability 79.51 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 0 Chemaxon Rule of Five No Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
Drug created at June 23, 2017 20:47 / Updated at June 12, 2020 16:53