- Onium Compounds
- Accession Number
Ions with the suffix -onium, indicating cations with coordination number 4 of the type RxA+ which are analogous to QUATERNARY AMMONIUM COMPOUNDS (H4N+). Ions include phosphonium R4P+, oxonium R3O+, sulfonium R3S+, chloronium R2Cl+
Drug Drug Description Succinylcholine A depolarizing skeletal muscle relaxant used adjunctly to anesthesia and for skeletal muscle relaxation during intubation, mechanical ventilation, and surgical procedures. Carbamoylcholine A direct acting miotic agent administered ophthalmically to decrease intraocular pressure after cataract surgery, and to induce miosis during surgery. Demecarium For the topical treatment of chronic open-angle glaucoma. Glycopyrronium An anticholinergic agent used to treat hyperhidrosis, severe drooling, COPD, used with other medications to treat ulcers, and used in anesthesia. Bethanechol A muscarinic agonist used to treat postoperative and postpartum nonobstructive functional urinary retention and neurogenic atony of the bladder with retention. Methacholine A parasympathomimetic bronchoconstrictor used to diagnose bronchial hyperreactivity in subjects who do not have clinically apparent asthma. Tridihexethyl Used as an adjunct in the treatment of peptic ulcer disease and in Acquired nystagmus Ambenonium A cholinesterase inhibitor that targets both muscarinic and nicotinic receptors indicated for the treatment of myasthenia gravis. Embutramide Not Available Isopropamide A long-acting anticholinergic drug used to relieve symptoms of spastic and painful symptoms of gastrointestinal conditions and symptoms of flu, colds, and related conditions. Ghavamiol Not Available N-Dodecyl-N,N-Dimethyl-3-Ammonio-1-Propanesulfonate Not Available Dodecyltrimethylammonium Not Available Tetramethylammonium Not Available Didecyldimethylammonium A disinfectant and microbicidal agent used in a variety of products. Methylnaltrexone A μ-opioid antagonist used for the treatment of opioid-induced constipation in palliative patients that are inadequately responding to laxative therapy. Ferric ammonium citrate Not Annotated Thonzonium A cationic surfactant used to disperse exudate and cellular debris, as well as enhance the penetration of antimicrobials. Brilliant green cation An ingredient used in topical medications to prevent infections of the umbilical cord. Ichthammol Ichthammol is also referred to as ammonium bituminosulfonate or ammonium bituminosulphonate. It is an ammonium salt of dark sulfonated shale oil (bituminous schists) produced via distillation of the oil followed... Cetalkonium An antiseptic used as a preservative or to treat certain topical infections. Domiphen Anti-infective (topical), it is used for the treatment of Acute Infectious Dental Diseases and other conditions. Methylbenactyzium Not Annotated Valethamate An anticholinergic medication used to symptomatically manage conditions involving smooth muscle spasms including spastic constipation, dysmenorrhea, and gastrointestinal tract cramping. Otilonium A spasmolytic medication used to treat irritable bowel syndrome (IBS). Alcuronium A non-depolarizing skeletal muscle relaxant similar to tubocurarine. It is used as an anesthesia adjuvant. Penthienate Not Annotated Dioctyldimonium Not Annotated Distearyldimonium Not Annotated Choline A nutrient found in a wide variety of vitamins including pre-natal formulations. Oxyphenonium For the treatment of visceral spasms Metocurine iodide For use as an anesthesia adjunct to induce skeletal muscle relaxation and to reduce the intensity of muscle contractions in convulsive therapy. Gallamine triethiodide A nondepolarizing nerve blocker used in addition to anesthesia to cause skeletal muscle relaxation. Propantheline An antimuscarinic agent used to treat urinary incontinence, hyperhidrosis, as well as cramps and spasms of the stomach, intestines, and bladder. Methantheline For the treatment of peptic ulcer disease, irritable bowel syndrome, pancreatitis, gastritis, biliary dyskinesia, pylorosplasm, and reflex neurogenic bladder in children. Hexafluronium Used as an adjunct with succinylcholine (or suxamethonium chloride) to prolong muscle relaxation and to prevent succinylcholine-induced muscle fasciculations. Edrophonium A cholinesterase inhibitor used to diagnose and evaluate myasthenia gravis. Tubocurarine Tubocurarine is a non-depolarizing neuromuscular blocking agent and the first identified curare alkaloid. Curare is one of the names used to describe plant-derived poisons used by indigenous South Americans to... Decamethonium For use as a skeletal muscle relaxant Oxtriphylline A bronchodilator used for the treatment of asthma, bronchitis, COPD, and emphysema. Metocurine Metocurine is a muscle relaxant. Neostigmine A cholinesterase inhibitor used in the symptomatic treatment of myasthenia gravis by improving muscle tone. Choline magnesium trisalicylate Choline magnesium trisalicylate is used to reduce pain and inflammation caused by conditions such as arthritis. This medication is also used to treat fever in adults. Cetrimonium A compound that can be used as a topical antiseptic. Platelet Activating Factor Not Available N,N,N-Trimethyl-2-(phosphonooxy)ethanaminium Calcium and magnesium salts used therapeutically in hepatobiliary dysfunction. Butyrylthiocholine A sulfur-containing analog of butyrylcholine which is hydrolyzed by butyrylcholinesterase to butyrate and thiocholine. It is used as a reagent in the determination of butyrylcholinesterase activity. [PubChem] Betaine aldehyde Not Available C31G Investigated for use/treatment in contraception, HIV infection, and prevention of stdis. Perifosine Investigated for use/treatment in solid tumors, multiple myeloma, leukemia (unspecified), lung cancer, and brain cancer. Betaine A methyl group donor used for the treatment of homocystinuria to decrease elevated homocysteine blood levels. Lauryldimethylbetaine Not Available Tetraethylammonium Tetraethylammonium is an experimental drug with no approved indication. Hexamethonium A nicotinic cholinergic antagonist often referred to as the prototypical ganglionic blocker. It is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier. It has been... Miltefosine An antileishmanial agent used to treat leishmaniasis, a group of disease caused by parasites of the Leishmania type. Benzalkonium An antiseptic agent used as a preservative in medications or as a disinfectant in cleaning products. Benzethonium A medication used as to clean hands and clean minor cuts and scrapes. Light green SF yellowish Light green SF yellowish is a green triarylmethane dye that is used in the preparation of the staining solution which is widely used as a counterstain. It is used in... Cocamidopropyl betaine Cocamidopropyl betaine is a mixture of closely related organic compounds derived from coconut oil and dimethylaminopropylamine that typically acts as an amphoteric surfactant in cosmetics and personal care products. It... Citicoline An endogenous intermediate in the formation of phosphatidylcholine from choline which is thought to have neuroprotective effects. Benzododecinium Benzododecinium is used as an antiseptic/disinfectant compound. It has been marketed as a tincture for antiseptic product for wounds in the Czech Republic. Emepronium Not Annotated Benzoxonium An antiseptic indicated in skin disinfection and prevention of infections. Gallamine Not Annotated Decamethoxine Not Annotated Choline salicylate The oral gel is indicated for the relief of pain and discomfort of common mouth ulcers, cold sores, denture sore spots, infant teething and mouth ulcers, and sore spots due... Cetyltrimethylammonium naproxenate An anti-inflammatory and antiseptic agent indicated to treat mouth inflammation and pain , including that caused by tooth extraction. Fluorocholine F-18 A radiopharmaceutical indicated in PET scans of the prostate.
- Drugs & Drug Targets