Dermatitis

Also known as: Inflammation; Skin / Skin Inflammation / Dermatitis (NOS) / Skin inflammation NOS (disorder) / Skin inflammation NOS / Eczema NOS / Eczema [Ambiguous] (disorder) / Inflammatory dermatosis (disorder) / Dermatitis &/or eczemas NOS / Dermatitis NOS (disorder) / Dermatitis NOS / Eczema / Dermatitis (disorder) / Dermatitis (disorder) [Ambiguous]

DrugDrug NameDrug Description
DB11482Balsam of PeruBalsam of Peru is found in diverse cosmetics and perfumes as well as a flavoring agent in cough syrups, lozenges, chewing gum, and candies. As a medical agent, balsam of...
DB13501BendazacA non-steroidal anti-inflammatory drug (NSAID) available as an eye drop for the treatment of cataracts and as a topical cream for the treatment of dermatitis, eczema, hives, skin ulcers and other inflammatory skin conditions.
DB01243ChloroxineAn antibacterial agent used for the treatment of dandruff and mild to moderately severe seborrheic dermatitis of the scalp.
DB13306ChlorquinaldolChlorquinaldol was used historically as a topical antiseptic agent for skin infections. It maintains use in European countries as a combination vaginal tablet with promestriene for use in the treatment...
DB00257ClotrimazoleA topical broad-spectrum antifungal agent used for the treatment of a wide variety of dermatophyte infections and candidiasis.
DB01234DexamethasoneA glucocorticoid available in various modes of administration that is used for the treatment of various inflammatory conditions, including bronchial asthma, as well as endocrine and rheumatic disorders.
DB14649Dexamethasone acetateCommonly known as decadron, dexamethasone acetate is a glucocorticosteroid previously marketed in the USA for the treatment of inflammatory respiratory, allergic, autoimmune, and other conditions.[T797,L10695,L14348] Developed in 1957, dexamethasone is...
DB13679DexchlorpheniramineA chlorpheniramine enantiomer antihistamine indicated in the treatment of sunburns, insect bites, and allergic reactions of the skin.
DB09095DifluocortoloneA topical corticosteroid used for the symptomatic treatment of inflammatory skin disorders like eczema, seborrheic eczema, lichen planus and psoriasis.
DB01127EconazoleA topical antifungal used to treat tinea pedis, tinea cruris, tinea corporis, cutaneous candidiasis and tinea versicolor.
DB00663FlumethasoneA corticosteroid used to treat contact dermatitis, atopic dermatitis, eczema, psoriasis, diaper rash, and other skin conditions.
DB08971FluocortoloneA glucocorticoid used topically for localized skin reactions and also orally for systemic use.
DB00588Fluticasone propionateA glucocorticoid used to treat asthma, inflammatory pruritic dermatoses, and nonallergic rhinitis.
DB00741HydrocortisoneA glucocorticoid used to treat corticosteroid-responsive dermatoses, endocrine disorders, immune conditions, and allergic disorders.
DB14104Linoleic acidNot Annotated
DB13092MeclocyclineA tetracycline antibiotic indicated in the treatment of susceptible skin infections, bacterial vaginitis, vulvovaginitis, and cervicitis.
DB00916MetronidazoleA nitroimidazole used to treat trichomoniasis, amebiasis, inflammatory lesions of rosacea, and bacterial infections, as well as prevent postoperative infections.
DB00764MometasoneA corticosteroid with no indications.
DB14512Mometasone furoateA corticosteroid used to treat asthma, allergic rhinitis, nasal congestion, nasal polyps, dermatitis, and pruritus.
DB00994NeomycinAn aminoglycoside antibiotic agent used orally and topically to treat a wide variety of infections in the body.
DB03255PhenolAn antiseptic and disinfectant used in a variety of settings.
DB15840Pine tarA medication indicated in itchy, inflamed, and flaky skin conditions.
DB01323St. John's WortAn herbal ingredient used in non-prescription therapeutic products for the short-term treatment of minor skin irritations, insomnia, depression, and anxiety.
DB00620TriamcinoloneA glucocorticoid used to treat a wide variety of inflammatory conditions of organ systems and tissues.
DB03904UreaA keratolytic emollient used to treat hyperkeratotic lesions and moisturize the skin.
DrugDrug NameTargetType
DB13501BendazacFree radicalstarget
DB13501BendazacProstaglandin G/H synthase 1target
DB13501BendazacProstaglandin G/H synthase 2target
DB00257ClotrimazoleIntermediate conductance calcium-activated potassium channel protein 4target
DB00257ClotrimazoleCytochrome P450 2D6enzyme
DB00257ClotrimazoleCytochrome P450 2C8enzyme
DB00257ClotrimazoleCytochrome P450 3A4enzyme
DB00257ClotrimazoleCytochrome P450 2B6enzyme
DB00257ClotrimazoleP-glycoprotein 1transporter
DB00257ClotrimazoleCytochrome P450 2A6enzyme
DB00257ClotrimazoleCytochrome P450 2C9enzyme
DB00257ClotrimazoleCytochrome P450 2E1enzyme
DB00257ClotrimazoleCytochrome P450 3A7enzyme
DB00257ClotrimazoleCytochrome P450 51target
DB00257ClotrimazoleNuclear receptor subfamily 1 group I member 2target
DB00257ClotrimazoleHydroxycarboxylic acid receptor 2target
DB00257ClotrimazoleBile salt export pumptransporter
DB00257ClotrimazoleSolute carrier organic anion transporter family member 1B1transporter
DB00257ClotrimazoleSolute carrier organic anion transporter family member 1B3transporter
DB00257ClotrimazoleErgosteroltarget
DB01234DexamethasoneGlucocorticoid receptortarget
DB01234DexamethasoneAnnexin A1target
DB01234DexamethasoneNitric oxide synthase, inducibletarget
DB01234DexamethasoneNuclear receptor subfamily 0 group B member 1target
DB01234DexamethasoneCytochrome P450 3A4enzyme
DB01234DexamethasoneCytochrome P450 3A5enzyme
DB01234DexamethasoneCytochrome P450 3A7enzyme
DB01234DexamethasoneBile salt export pumptransporter
DB01234DexamethasoneP-glycoprotein 1transporter
DB01234DexamethasoneCanalicular multispecific organic anion transporter 1transporter
DB01234DexamethasoneSolute carrier organic anion transporter family member 1A2transporter
DB01234DexamethasoneATP-binding cassette sub-family G member 2transporter
DB01234DexamethasoneSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
DB01234DexamethasoneCytochrome P450 1A1enzyme
DB01234DexamethasoneCytochrome P450 2A6enzyme
DB01234DexamethasoneCytochrome P450 2B6enzyme
DB01234DexamethasoneCytochrome P450 2C19enzyme
DB01234DexamethasoneCytochrome P450 2C8enzyme
DB01234DexamethasoneCytochrome P450 2E1enzyme
DB01234DexamethasoneCytochrome P450 3A43enzyme
DB01234DexamethasoneCytochrome P450 4A11enzyme
DB01234DexamethasoneNuclear receptor subfamily 1 group I member 2target
DB01234DexamethasoneCytochrome P450 11B1, mitochondrialenzyme
DB01234DexamethasoneSerum albumincarrier
DB01234DexamethasoneCorticosteroid 11-beta-dehydrogenase isozyme 2enzyme
DB01234DexamethasoneCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
DB01234DexamethasoneSolute carrier family 22 member 8transporter
DB14649Dexamethasone acetateGlucocorticoid receptortarget
DB14649Dexamethasone acetateAnnexin A1target
DB14649Dexamethasone acetateNitric oxide synthase, inducibletarget
DB14649Dexamethasone acetateNuclear receptor subfamily 0 group B member 1target
DB14649Dexamethasone acetateCytochrome P450 3A4enzyme
DB14649Dexamethasone acetateCytochrome P450 3A5enzyme
DB14649Dexamethasone acetateCytochrome P450 3A7enzyme
DB14649Dexamethasone acetateBile salt export pumptransporter
DB14649Dexamethasone acetateP-glycoprotein 1transporter
DB14649Dexamethasone acetateCanalicular multispecific organic anion transporter 1transporter
DB14649Dexamethasone acetateSolute carrier organic anion transporter family member 1A2transporter
DB14649Dexamethasone acetateATP-binding cassette sub-family G member 2transporter
DB14649Dexamethasone acetateSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
DB14649Dexamethasone acetateCytochrome P450 1A1enzyme
DB14649Dexamethasone acetateCytochrome P450 2A6enzyme
DB14649Dexamethasone acetateCytochrome P450 2B6enzyme
DB14649Dexamethasone acetateCytochrome P450 2C19enzyme
DB14649Dexamethasone acetateCytochrome P450 2C8enzyme
DB14649Dexamethasone acetateCytochrome P450 2E1enzyme
DB14649Dexamethasone acetateCytochrome P450 3A43enzyme
DB14649Dexamethasone acetateCytochrome P450 4A11enzyme
DB14649Dexamethasone acetateNuclear receptor subfamily 1 group I member 2target
DB14649Dexamethasone acetateCytochrome P450 11B1, mitochondrialenzyme
DB14649Dexamethasone acetateSerum albumincarrier
DB14649Dexamethasone acetateCorticosteroid 11-beta-dehydrogenase isozyme 2enzyme
DB14649Dexamethasone acetateCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
DB14649Dexamethasone acetateSolute carrier family 22 member 8transporter
DB13679DexchlorpheniramineCytochrome P450 2D6enzyme
DB09095DifluocortoloneAnnexin A3target
DB09095DifluocortoloneGlucocorticoid receptortarget
DB09095DifluocortoloneCytochrome P450 3A4enzyme
DB09095DifluocortoloneCytochrome P450 3A5enzyme
DB01127EconazoleCytochrome P450 19A1enzyme
DB01127EconazoleCytochrome P450 2E1enzyme
DB01127EconazoleCytochrome P450 3A4enzyme
DB01127EconazoleCytochrome P450 51target
DB01127EconazoleNuclear receptor subfamily 1 group I member 2target
DB00663FlumethasoneCorticosteroid-binding globulincarrier
DB00663FlumethasoneGlucocorticoid receptortarget
DB00663FlumethasoneCytochrome P450 3A4enzyme
DB08971FluocortoloneCytochrome P450 3A4enzyme
DB08971FluocortoloneCytochrome P450 3A5enzyme
DB00588Fluticasone propionateCorticosteroid-binding globulincarrier
DB00588Fluticasone propionateCytosolic phospholipase A2target
DB00588Fluticasone propionateGlucocorticoid receptortarget
DB00588Fluticasone propionateCytochrome P450 3A4enzyme
DB00588Fluticasone propionateProgesterone receptortarget
DB00588Fluticasone propionateMineralocorticoid receptortarget
DB00588Fluticasone propionateCytochrome P450 3A5enzyme
DB00588Fluticasone propionateCytochrome P450 3A7enzyme
DB00588Fluticasone propionateCytochrome P450 2C8enzyme
DB00588Fluticasone propionateSolute carrier organic anion transporter family member 1B1carrier
DB00588Fluticasone propionateP-glycoprotein 1transporter
DB00588Fluticasone propionateSolute carrier organic anion transporter family member 1B1transporter
DB00741HydrocortisoneAnnexin A1target
DB00741HydrocortisoneGlucocorticoid receptortarget
DB00741HydrocortisoneSex hormone-binding globulincarrier
DB00741HydrocortisoneCytochrome P450 3A4enzyme
DB00741HydrocortisoneCytochrome P450 3A5enzyme
DB00741HydrocortisoneCytochrome P450 3A7enzyme
DB00741HydrocortisoneP-glycoprotein 1transporter
DB00741HydrocortisoneSolute carrier organic anion transporter family member 1A2transporter
DB00741HydrocortisoneCytochrome P450 11B1, mitochondrialenzyme
DB00741HydrocortisoneCytochrome P450 11B2, mitochondrialenzyme
DB00741HydrocortisoneCytochrome P450 2C8enzyme
DB00741HydrocortisoneCorticosteroid-binding globulincarrier
DB00741HydrocortisoneSolute carrier family 22 member 8transporter
DB00741Hydrocortisone3-oxo-5-beta-steroid 4-dehydrogenaseenzyme
DB00741Hydrocortisone3-oxo-5-alpha-steroid 4-dehydrogenase 2enzyme
DB00741HydrocortisoneCorticosteroid 11-beta-dehydrogenase isozyme 2enzyme
DB00741HydrocortisoneCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
DB00741HydrocortisoneCytochrome P450 2A6enzyme
DB00741HydrocortisoneCytochrome P450 1B1enzyme
DB00741HydrocortisoneCytochrome P450 2B6enzyme
DB00741HydrocortisoneCytochrome P450 2C9enzyme
DB00741HydrocortisoneCytochrome P450 2C19enzyme
DB13092MeclocyclineOuter membrane protein Ftransporter
DB13092MeclocyclineOuter membrane porin Ctransporter
DB13092Meclocycline30S ribosomal protein S7target
DB13092MeclocyclineTetX family tetracycline inactivation enzymeenzyme
DB00916MetronidazoleOxygen-insensitive NADPH nitroreductasetarget
DB00916MetronidazoleCytochrome P450 2C9enzyme
DB00916MetronidazoleCytochrome P450 3A4enzyme
DB00916MetronidazoleCytochrome P450 2C8enzyme
DB00916MetronidazoleUDP-glucuronosyltransferase 1-1enzyme
DB00916MetronidazoleAnaerobic bacterial DNAtarget
DB00916MetronidazoleProtozoal DNAtarget
DB00916MetronidazoleP-glycoprotein 1transporter
DB00916MetronidazoleCytochrome P450 2A6enzyme
DB00916MetronidazoleCytochrome P450 3A5enzyme
DB00916MetronidazoleCytochrome P450 3A7enzyme
DB00764MometasoneGlucocorticoid receptortarget
DB00764MometasoneCytochrome P450 2C8enzyme
DB00764MometasoneProgesterone receptortarget
DB00764MometasoneCytochrome P450 3A4enzyme
DB00764MometasoneCytochrome P450 3A5enzyme
DB14512Mometasone furoateGlucocorticoid receptortarget
DB14512Mometasone furoateCytochrome P450 2C8enzyme
DB14512Mometasone furoateProgesterone receptortarget
DB14512Mometasone furoateCytochrome P450 3A4enzyme
DB14512Mometasone furoateCytochrome P450 3A5enzyme
DB00994Neomycin30S ribosomal protein S12target
DB00994Neomycin16S ribosomal RNAtarget
DB00994NeomycinExtracellular calcium-sensing receptortarget
DB03255PhenolThermolysintarget
DB03255PhenolSerum albumintarget
DB01323St. John's WortP-glycoprotein 1transporter
DB01323St. John's WortCytochrome P450 3A4enzyme
DB01323St. John's WortCytochrome P450 2D6enzyme
DB01323St. John's WortCytochrome P450 2C19enzyme
DB00620TriamcinoloneCorticosteroid-binding globulincarrier
DB00620TriamcinoloneGlucocorticoid receptortarget
DB00620TriamcinoloneCytochrome P450 3A4enzyme
DB00620TriamcinoloneProstaglandin G/H synthase 2enzyme
DB00620TriamcinoloneCholinesteraseenzyme
DB00620TriamcinoloneCytochrome P450 3A5enzyme
DB00620TriamcinoloneCytochrome P450 3A7enzyme
DB00620TriamcinoloneSerum albumincarrier
DB03904UreaArginase-1target
DB03904UreaCarbonic anhydrase 2target
DB03904UreaCatenin beta-1target
DB03904UreaSulfoxide reductase catalytic subunit YedYtarget
DB03904UreaUrea transporter 2transporter
DB03904UreaUrea transporter 1transporter
DB03904UreaDihydrofolate reductasetarget
DrugDrug NamePhaseStatusCount
DB09539Omega-3-acid ethyl esters0Recruiting1
DB00341Cetirizine1Completed1
DB12159Dupilumab1Completed1
DB06282Levocetirizine1Completed1
DB09567Olive oil1 / 2Unknown Status1
DB09321Zinc oxide1 / 2Unknown Status1
DB12023Benralizumab2Recruiting1
DB00567Cephalexin2Recruiting1
DB11074Dimethicone2Recruiting1
DB00254Doxycycline2Recruiting1
DB11064Homosalate2Recruiting1
DB11096Meradimate2Recruiting1
DB00704Naltrexone2Not Yet Recruiting1
DB00704Naltrexone2Withdrawn1
DB09496Octinoxate2Recruiting1
DB09535Octocrylene2Recruiting1
DB14762Risankizumab2Completed1
DB01656Roflumilast2Withdrawn1
DB01015Sulfamethoxazole2Recruiting1
DB00440Trimethoprim2Recruiting1
DB09321Zinc oxide2Recruiting1
DB09321Zinc oxide2Withdrawn2
DB14973Abrocitinib3Completed2
DB04890Bepotastine3Completed1
DB00341Cetirizine3Completed1
DB00283Clemastine3Unknown Status1
DB00283Clemastine3Withdrawn1
DB00967Desloratadine3Completed1
DB01234Dexamethasone3Unknown Status1
DB01234Dexamethasone3Withdrawn1
DB12159Dupilumab3Completed1
DB00741Hydrocortisone3Completed1
DB00920Ketotifen3Completed1
DB11914Lebrikizumab3Active Not Recruiting1
DB06282Levocetirizine3Completed1
DB09321Zinc oxide3Withdrawn1
DB00864Tacrolimus4Completed1
DB01190ClindamycinNot AvailableCompleted1
DB01013Clobetasol propionateNot AvailableCompleted1
DB00199ErythromycinNot AvailableCompleted1
DB12961Leukotriene B4Not AvailableCompleted1
DB00860PrednisoloneNot AvailableCompleted1