NMOSD

Also known as: NMO Spectrum Disorder / Neuromyelitis Optica Spectrum Disorders / NMO Spectrum Disorder (NMOSD) / Neuromyelitis Optica Spectrum Disorder / Devic's disease / Neuromyelitis optica (disorder) / Neuromyelitis optica / Neuro-optic myelitis

DrugDrug NameDrug Description
DB01257EculizumabA recombinant humanized monoclonal antibody used to reduce the risk of hemolysis in paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS).
DB12530InebilizumabA humanized anti-CD19 cytolytic monoclonal antibody for B-cell depletion in autoimmune conditions. Currently approved only for neuromyelitis optica spectrum disorder (NMOSD).
DB15762SatralizumabA subcutaneously injected anti-IL-6 receptor monoclonal antibody for the treatment of neuromyelitis optica spectrum disorder (NMOSD).
DrugDrug NamePhaseStatusCount
DB00531Cyclophosphamide0Recruiting1
DB01073Fludarabine0Recruiting1
DB16036ABX-14311Completed1
DB16104Batoclimab1Completed1
DB00112Bevacizumab1Completed1
DB11850Ublituximab1Completed1
DB08879Belimumab1 / 2Recruiting1
DB06650Ofatumumab1 / 2Recruiting1
DB06273Tocilizumab1 / 2Completed1
DB00188Bortezomib2Completed1
DB16741Bortezomib D-mannitol2Completed1
DB00028Human immunoglobulin G2Completed1
DB00098Antithymocyte immunoglobulin (rabbit)2 / 3Withdrawn1
DB00993Azathioprine2 / 3Completed2
DB09110Coenzyme M2 / 3Withdrawn1
DB00531Cyclophosphamide2 / 3Withdrawn1
DB09331Daratumumab2 / 3Not Yet Recruiting1
DB01257Eculizumab2 / 3Recruiting1
DB00099Filgrastim2 / 3Withdrawn1
DB00028Human immunoglobulin G2 / 3Withdrawn1
DB00959Methylprednisolone2 / 3Withdrawn1
DB14644Methylprednisolone hemisuccinate2 / 3Withdrawn1
DB11580Ravulizumab2 / 3Recruiting1
DB00073Rituximab2 / 3Completed1
DB00073Rituximab2 / 3Withdrawn1
DB06273Tocilizumab2 / 3Completed1
DB00993Azathioprine3Active Not Recruiting1
DB01257Eculizumab3Completed1
DB01257Eculizumab3Terminated1
DB00688Mycophenolate mofetil3Active Not Recruiting1
DB11580Ravulizumab3Active Not Recruiting1
DB15762Satralizumab3Active Not Recruiting1
DB15762Satralizumab3Completed2
DB15762Satralizumab3Recruiting1
DB01204Mitoxantrone4Unknown Status1
DB00688Mycophenolate mofetil4Unknown Status1
DB00635Prednisone4Unknown Status1
DB00073Rituximab4Completed1
DB15762Satralizumab4Recruiting1
DB00993AzathioprineNot AvailableRecruiting1
DB00688Mycophenolate mofetilNot AvailableRecruiting1
DB06650OfatumumabNot AvailableNot Yet Recruiting1
DB16272OrelabrutinibNot AvailableNot Yet Recruiting1
DB00073RituximabNot AvailableRecruiting1