Activated PI3 kinase delta syndrome

Also known as: Activated PI3Kdelta Syndrome APDS / Activated PI3K-delta Syndrome / Activated PI3K-delta syndrome (disorder)

Drug	Drug Name	Drug Description
DB16217	Leniolisib	A phosphoinositide 3-kinase-delta inhibitor that is used to treat activated phosphoinositide 3-kinase delta syndrome.

Drug	Drug Name	Target	Type
DB16217	Leniolisib	Cytochrome P450 1A2	enzyme
DB16217	Leniolisib	ATP-binding cassette sub-family G member 2	transporter
DB16217	Leniolisib	Solute carrier organic anion transporter family member 1B1	transporter
DB16217	Leniolisib	Solute carrier organic anion transporter family member 1B3	transporter
DB16217	Leniolisib	P-glycoprotein 1	transporter
DB16217	Leniolisib	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	target
DB16217	Leniolisib	Cytochrome P450 3A4	enzyme
DB16217	Leniolisib	Cytochrome P450 3A5	enzyme
DB16217	Leniolisib	Cytochrome P450 2D6	enzyme
DB16217	Leniolisib	Cytochrome P450 1A1	enzyme

Drug	Drug Name	Phase	Status	Count
DB00877	Sirolimus	1 / 2	Recruiting	1
DB16253	Nemiralisib	2	Completed	1