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Lidocaine (Antiarrhythmic) Action Pathway
smpdb.ca/view/SMP0000328Drug actionThis pathway illustrates the lidocaine targets involved in antiarrhythmic therapy. Contractile activity of cardiac myocytes is elicited via action potentials mediated by a number of ion channel proteins. During rest, or diastole, cells m...
Hereditary Coproporphyria (HCP)
smpdb.ca/view/SMP0000342Diseasefollowing are some measures which are designed to help prevent and/or regulate the above and more symptoms: a diet which is high in carbohydrates and sugars, and a balanced lifestyle which abstains from alcohol
Docetaxel Action Pathway
smpdb.ca/view/SMP0000435Drug actionDocetaxel, a semisynthetic analogue of paclitaxel, is an anticancer agent classified as a microtubule-stabilizing agent. Similar to paclitaxel, it exerts cell killing effects by disrupting mitosis in dividing cells. Microtubules are made...
Primary Hyperoxaluria II, PH2
smpdb.ca/view/SMP0000558DiseasePrimary hyperolaria type 2 (PH2) is a rare condition resulting from glyoxylate reductase/hydroxypyruvate reductase (GR/HPR) enzyme deficiency. PH2 results in calcium oxalate (also known as oxalic acid) deposits and end-stage renal diseas...
Lidocaine (Local Anaesthetic) Metabolism Pathway
smpdb.ca/view/SMP0000620Drug metabolismLidocaine exerts its local anaesthetic effect by blocking voltage-gated sodium channels in peripheral neurons. Lidocaine diffuses across the neuronal plasma membrane in its uncharged base form. Once inside the cytoplasm, it is protonated...
Naloxone Action Pathway
smpdb.ca/view/SMP0000688Drug actionNaloxone is also a type of medication that are used for manage opioid or alcohol dependence.
Acetaminophen Action Pathway
smpdb.ca/view/SMP0000710Drug actionAcetaminophen (also named paracetamol or APAP) is not a Nonsteroidal anti-inflammatory drugs (NSAIDs). However, it still can be used to treat pain and fever. Acetaminophen can block prostaglandin synthesis by the action of inhibition of ...
Drugs: Glutamic acid · Glutathione · Acetaminophen · Dinoprostone · Calcium · Magnesium cation +5 moreDiphenhydramine H1-Antihistamine Action
smpdb.ca/view/SMP0058785Drug actionDiphenhydramine is a first-generation ethanolamine H1-antihistamine. H1-antihistamines interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory process in order to treat conditions ...
Metabolism and Physiological Effects of Phenol
smpdb.ca/view/SMP0123255MetabolicPhenol is a phenolic compound that is formed through gut microbial metabolism from dietary tyrosine. After being transported into gut microbes, tyrosine undergoes a reaction with the enzyme tyrosine phenol-lyase to form phenol. Phenol th...
Diazepam Action Pathway
smpdb.ca/view/SMP0124471Drug actionDue to its effects it's used to treat severe anxiety disorders, short term insomnia, acute repetitive seizures, alcohol withdrawal. and possibly epilepsy. … Overdose of benzodiazepines like diazepam should be closely monitored especially if the patient has taken other respiratory depressing drugs like alcohol as it could be fatal.