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Azathioprine Action Pathway
smpdb.ca/view/SMP0000427Drug actionAzathioprine is a purine antimetabolite prodrug that exerts cytotoxic effects via three mechanisms: via incorporation of thiodeoxyguanosine triphosphate into DNA and thioguanosine triphosphate into RNA, inhibition of de novo synthesis of...
Drugs: Tetrahydrofolic acid · Ademetionine · Aspartic acid · L-Glutamine · Adenosine phosphate · Glutamic acid +27 moreCaffeine Nervous Action Pathway
smpdb.ca/view/SMP0125297Drug actionCaffeine is a central nervous system stimulant present in tea, coffee, cola beverages, analgesic drugs, and agents used to increase alertness. Consistent intake of caffeine increases the population of adenosine receptors, which can poten...
Drugs: Pyridoxal phosphate · Glutamic acid · Caffeine · Norepinephrine · Adenosine · Calcium +1 moreMetabolism and Physiological Effects of Uric acid
smpdb.ca/view/SMP0124845MetabolicUric acid is formed from purine catabolism. Purines can be made endogenously in the body or can be obtained exogenously from foods such as red meat. The purines are guanine and adenine. These undergo metabolism in the liver to form uric ...
Allopurinol Action Pathway (New)
smpdb.ca/view/SMP0125128Drug actionAllopurinol is a xanthine oxidase inhibitor used to reduce urinary and serum uric acid concentrations in patients with gout, recurrent calcium oxalate calculi, and various malignancies. Allopurinol administration can be in two forms, eit...
Ensulizole Drug Metabolism
smpdb.ca/view/SMP0130813MetabolicEnsulizole is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis. Ensulizole passes through the liver and is then excreted from the body mainly through the kidney.
Drugs: EnsulizoleMetabolism and Physiological Effects of Xanthine
smpdb.ca/view/SMP0124865MetabolicXanthine is formed from purine catabolism. Purines can be made endogenously in the body or can be obtained exogenously from foods such as red meat. The purines are guanine and adenine. These undergo metabolism in the liver to form xanthi...
Metabolism and Physiological Effects of Xanthosine
smpdb.ca/view/SMP0124866MetabolicXanthosine is formed from purine catabolism. Purines can be made endogenously in the body or can be obtained exogenously from foods such as red meat. The purines are guanine and adenine. These undergo metabolism in the liver to form xant...