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Lysophosphatidic Acid LPA2 Signalling
smpdb.ca/view/SMP0063753SignalingLysophosphatidic acid (LPA) is a water-soluble phospholipid derivative and a potent signalling molecule that binds to six known lysophosphatidic acid receptors (LPARs), named LPA1-LPA6. … LPC, LPE, LPS) into LPA via autotaxin (ATX/Enpp2) and (2) the conversion of phosphatidic acid (PA) into LPA via phospholipase A1 or A2 (PLA1/PLA2).
Enzymes: Lysophosphatidic acid receptor 2Lysophosphatidic Acid LPA4 Signalling
smpdb.ca/view/SMP0063756SignalingLysophosphatidic acid (LPA) is a water-soluble phospholipid derivative and a potent signalling molecule that binds to six known lysophosphatidic acid receptors (LPARs), named LPA1-LPA6. … LPC, LPE, LPS) into LPA via autotaxin (ATX/Enpp2) and (2) the conversion of phosphatidic acid (PA) into LPA via phospholipase A1 or A2 (PLA1/PLA2).
Enzymes: Lysophosphatidic acid receptor 4Mycophenolic Acid Action Pathway
smpdb.ca/view/SMP0122722Drug actionMycophenolic acid is a selective, reversible and potent inhibitor of the enzyme. … It is also possible that mycophenolic acid inhibits leukocyte recruitment to inflammation and graft rejection sites. Mycophenolic acid is administered orally in the form of a delayed release tablet.
Drugs: Tetrahydrofolic acid · Aspartic acid · L-Glutamine · Adenosine phosphate · Glutamic acid · Glycine +14 moreMeclofenamic acid Action Pathway
smpdb.ca/view/SMP0126104Drug actionMeclofenamic acid is administered as an oral capsule. … Meclofenamic acid inhibits the action of COX-1 and COX-2 on the endoplasmic reticulum membrane. This reduces the formation of prostaglandin H2 and therefore, prostaglandin E2 (PGE2).
Drugs: Glutathione · Dinoprostone · Meclofenamic acid · Calcium · Mesoheme · Prostaglandin G2 +1 moreGlycolic acid Drug Metabolism
smpdb.ca/view/SMP0130509MetabolicGlycolic acid passes through the liver and is then excreted from the body mainly through the kidney. … Glycolic acid is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis.
Drugs: Glycolic acidClodronic acid Drug Metabolism
smpdb.ca/view/SMP0130640MetabolicClodronic acid passes through the liver and is then excreted from the body mainly through the kidney. … Clodronic acid is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis.
Drugs: Clodronic acidHyaluronic acid Drug Metabolism
smpdb.ca/view/SMP0130655MetabolicHyaluronic acid passes through the liver and is then excreted from the body mainly through the kidney. … Hyaluronic acid is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis.
Drugs: Hyaluronic acidIndigotindisulfonic acid Drug Metabolism
smpdb.ca/view/SMP0130815MetabolicIndigotindisulfonic acid passes through the liver and is then excreted from the body mainly through the kidney. … Indigotindisulfonic acid is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis.
Drugs: Indigotindisulfonic acidAcetylsalicylic Acid Action Pathway
smpdb.ca/view/SMP0000083Drug actionCOX-1 and -2 catalyze the conversion of arachidonic acid to prostaglandin G2 and prostaglandin G2 to prostaglandin H2. … Acetylsalicylic acid, also known as ASA or aspirin, belongs to a class of drugs known as non-steroidal anti-inflammatory drugs (NSAIDs).
Drugs: Glutamic acid · Glutathione · Dinoprostone · Acetylsalicylic acid · Calcium · Magnesium cation +5 morePhytanic Acid Peroxisomal Oxidation
smpdb.ca/view/SMP0000450MetabolicPhytanic acid, a branched chain fatty acid, is an important component of fatty acid intake, occuring in meat, fish and dairy products. … Due to its methylation, it cannot be a substrate for acyl-CoA dehydrogenase and cannot enter the mitochondrial beta oxidation pathway.