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Displaying results 151 - 160 of 2123 in total
  1. Pathway

    Minaprine Acetylcholinesterase Antidepressant Action Pathway

    smpdb.ca/view/SMP0126689
    Drug action

    Firstly, this drug binds as an antagonist to the serotonin type 2 receptors (C, B, and C). Secondly, it can also antagonize the dopamine D1 and D2 type receptors. … The first one is found in cells located in the periphery and breakdown serotonin, norepinephrine, epinephrine, dopamine, and tyramine.

    Drugs: Choline · Minaprine · Calcium · Magnesium cation · Acetylcholine · Acetic acid
    Enzymes: Voltage-dependent L-type calcium channel subunit beta-4, Voltage-dependent L-type calcium channel subunit beta-1
  2. Pathway

    Metrifonate Action Pathway

    smpdb.ca/view/SMP0126725
    Drug action

    and alzheimer's disease. … While binding to acetylcholinesterase it prevents the breakdown of acetylcholine, allowing the neurotransmitter to interact with the receptors that help aid memory and cognition in patients with dementia

    Drugs: Choline · Calcium · Magnesium cation · Acetylcholine · Acetic acid · Metrifonate
    Enzymes: Voltage-dependent L-type calcium channel subunit beta-4, Voltage-dependent L-type calcium channel subunit beta-1
  3. Pathway

    Roxatidine Acetate H2 Anti-Histamine Action Pathway

    smpdb.ca/view/SMP0123168
    Drug action

    Roxatidine Acetate is an histamine H2 receptor antagonist used to treat stomach ulcers and Gastroesophageal Reflux Disease (GERD). … After being taken orally, it is absorbed in the GI tract and travels through the blood to get to the stomach epithelium.

    Drugs: ATP · Potassium cation · Magnesium cation · Zinc · Cyclic adenosine monophosphate · Roxatidine acetate
  4. Pathway

    Pseudoephedrine Action Pathway

    smpdb.ca/view/SMP0125255
    Drug action

    Pseudoephedrine is alpha and beta agonist used to treat nasal and sinus congestion as well as allergic rhinitis. It is in many cold and sinus medicines as well as allergy medicine. … Diacylglycerol activates protain kinase C which activates the voltage-dependent calcium channel, allowing calcium to enter the cell.

    Drugs: Ascorbic acid · Norepinephrine · Pseudoephedrine · Dopamine · Calcium · Magnesium cation +1 more
    Enzymes: Voltage-dependent P/Q-type calcium channel subunit alpha-1A, Voltage-dependent L-type calcium channel subunit beta-1
  5. Pathway

    Methylphosphinic Acid Action Pathway

    smpdb.ca/view/SMP0126733
    Drug action

    Further research needs to be conducted in order to confirm results, safety and confirm the mechanism of action. … Methylphosphinic acid is an experimental drug being tested to be a possible cholinesterase inhibitor, as it appears to inhibit the breakdown of acetylcholine.

    Drugs: Choline · Calcium · Magnesium cation · Methylphosphinic Acid · Acetylcholine · Acetic acid
    Enzymes: Voltage-dependent L-type calcium channel subunit beta-4, Voltage-dependent L-type calcium channel subunit alpha-1F
  6. Pathway

    Inositol Metabolism

    smpdb.ca/view/SMP0000011
    Metabolic

    Inositol is abundant in many commonly consumed foods such as bran-rich cereals, beans, nuts, and fruit (particularly cantaloupe, melons, and oranges). … For phosphatidyliositol, phosphatidylinositol synthase generates it with the substrates CDP-diacylglycerol and myo-inositol.

    Drugs: ATP · Calcium · Magnesium cation · Iron · 1D-myo-inositol 1,3,4-trisphosphate · Pyrophosphoric acid +1 more
    Enzymes: Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1
  7. Pathway

    Tafluprost Action Pathway

    smpdb.ca/view/SMP0175201
    Drug action

    Tafluprost may also promote ulcer healing by increasing mucus and bicarbonate secretion and thickening the mucosal bilayer so the mucosa can generate new cells. … With reduced protein kinase A activation, this decreases the activity of the proton pump, fewer H+ ions are pumped into the lumen, reducing the acidity and thus allowing stomach ulcers to heal and reducing

    Drugs: ATP · Potassium cation · Magnesium cation · Zinc · Cyclic adenosine monophosphate · Pyrophosphoric acid +1 more
  8. Pathway

    Travoprost Action Pathway

    smpdb.ca/view/SMP0175203
    Drug action

    Travoprost may also promote ulcer healing by increasing mucus and bicarbonate secretion and thickening the mucosal bilayer so the mucosa can generate new cells. … With reduced protein kinase A activation, this decreases the activity of the proton pump, fewer H+ ions are pumped into the lumen, reducing the acidity and thus allowing stomach ulcers to heal and reducing

    Drugs: ATP · Travoprost · Potassium cation · Magnesium cation · Zinc · Cyclic adenosine monophosphate +1 more
  9. Pathway

    Misoprostol Action Pathway

    smpdb.ca/view/SMP0124718
    Drug action

    Misoprostol may also promote ulcer healing by increasing mucus and bicarbonate secretion and thickening the mucosal bilayer so the mucosa can generate new cells. … With reduced protein kinase A activation, this decreases the activity of the proton pump, fewer H+ ions are pumped into the lumen, reducing the acidity and thus allowing stomach ulcers to heal and reducing

    Drugs: ATP · Misoprostol · Potassium cation · Magnesium cation · Zinc · Cyclic adenosine monophosphate +1 more
  10. Pathway

    Latanoprost Action Pathway

    smpdb.ca/view/SMP0175204
    Drug action

    Latanoprost may also promote ulcer healing by increasing mucus and bicarbonate secretion and thickening the mucosal bilayer so the mucosa can generate new cells. … With reduced protein kinase A activation, this decreases the activity of the proton pump, fewer H+ ions are pumped into the lumen, reducing the acidity and thus allowing stomach ulcers to heal and reducing

    Drugs: ATP · Latanoprost · Potassium cation · Magnesium cation · Zinc · Cyclic adenosine monophosphate +1 more