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Toothache
go.drugbank.com/conditions/DBCOND0001908Drugs: Acetaminophen · Acetylsalicylic acid · Caffeine · Carbaspirin calcium · Clove oil · Naproxen +2 moreSynonyms: Pain in toothPost Nasal Drip
go.drugbank.com/conditions/DBCOND0039260Drugs: DL-MethylephedrineSynonyms: (Post nasal drip) or (C/O catarrh)Trabectedin
go.drugbank.com/drugs/DB05109ApprovedInvestigationalIt is approved for use in Europe, Russia and South Korea for the treatment of advanced soft tissue sarcoma. … Trabectedin has a unique mechanism of action. It binds to the minor groove of DNA interfering with cell division and genetic transcription processes and DNA repair machinery.
Categories: Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic IndexProducts: YONDELIS 1 MG IV KONSANTRE INFUZYONLUK COZELTI ICIN TOZ, Trabectedin TEVA 1 mg Pulver für ein Konzentrat zur Herstellung einer InfusionslösungTiotropium
go.drugbank.com/drugs/DB01409ApprovedInvestigationalTiotropium is a long-acting, antimuscarinic bronchodilator used in the management of chronic obstructive pulmonary disease (COPD) and asthma. … [A180163,L7084,L7087,L7090,L7093] Tiotropium acts mainly on M3 muscarinic receptors located in the airways to produce smooth muscle relaxation and bronchodilation.
Mixtures: SPIOLTO®RESPIMAT®, SPIOLTO®RESPIMAT®Categories: Agents to Treat Airway Disease, Cytochrome P-450 SubstratesVinorelbine
go.drugbank.com/drugs/DB00361ApprovedInvestigationalIt was found that there was 4.3-fold variation in vinorelbine clearance across the cohort, suggesting a strong influence of genetics on the clearance of this drug [L2002]. … It was initially approved in the USA in 1990's for the treatment of NSCLC [L2010]. It is a third-generation vinca alkaloid.
Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 SubstratesSynonyms: 5'-NoranhydrovinblastineLecithin retinol acyltransferase
go.drugbank.com/bio_entities/BE0000900TargetEnzymeHumansLRAT plays a critical role in vision (Probable). … It provides the all-trans retinyl ester substrates for the isomerohydrolase which processes the esters into 11-cis-retinol in the retinal pigment epithelium; due to a membrane-associated alcohol dehydrogenase
Synonyms: Phosphatidylcholine--retinol O-acyltransferaseGlycopyrronium
go.drugbank.com/drugs/DB00986ApprovedInvestigationalVet approved[L33105] Glycopyrronium is commonly prescribed as a first line treatment for a wide variety indications and is considered to have a wider therapeutic window than [tiotropium]. … [A233535,A233540] Early research into glycopyrronium use was for its indication as an adjunct therapy in the treatment of peptic ulcers.
Mixtures: TRİMBOW 87/5/9 MCG AEROSOL İNHALASYON ÇÖZELTİSİ, 120 DOZ, TRYDONİS 87 MCG/5 MCG/9 MCG AEROSOL İNHALASYONU, ÇÖZELTİ, 120 DOZCategories: MATE 1 Substrates, Cytochrome P-450 SubstratesHypotension
go.drugbank.com/conditions/DBCOND0020133Synonyms: Fall in blood pressure, Drop in blood pressureChoriocarcinoma
go.drugbank.com/conditions/DBCOND0017311Drugs: VincristineSynonyms: Choriocarcinoma, no ICD-O subtypeCystathionine gamma-synthase
go.drugbank.com/bio_entities/BE0003209TargetEnzymeEscherichia coli (strain K12)In the absence of thiol, catalyzes gamma-elimination to form 2-oxobutanoate, succinate and ammonia. … Catalyzes the formation of L-cystathionine from O-succinyl-L-homoserine (OSHS) and L-cysteine, via a gamma-replacement reaction.
Synonyms: O-succinylhomoserine (thiol)-lyase