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Aluminum hydroxide
go.drugbank.com/drugs/DB06723ApprovedInvestigationalSubsequent increases in pH may inhibit the action of pepsin. An increase in bicarbonate ions and prostaglandins may also confer cytoprotective effects. … Aluminum hydroxide is an inorganic salt used as an antacid. It is a basic compound that acts by neutralizing hydrochloric acid in gastric secretions.
Mixtures: Maalox oral suspension in sachet, MULTIGEL IIProducts: GALAC H, GASTROVAN®Cupric sulfate
go.drugbank.com/drugs/DB06778ApprovedSome of its secondary uses are as a raw material in the preparation of other copper compounds, as a reagent in analytic chemistry, as an electrolyte for batteries and electroplating baths, and in medical … The average daily intake of copper in the USA is approximately 1 mg Cu with the diet being a primary source [A32221].
Synonyms: Copper(II) sulphate, Copper sulfate (1:1)International brands: M-Care, Hi Trace CopperBelinostat
go.drugbank.com/drugs/DB05015ApprovedInvestigationalThe safety and efficacy of belinostat is currently being evaluated for use in combination with traditional front-line therapies for the treatment of PTCL. … It was US-approved in July 2014 as a therapeutic agent for relapsed or refractory peripheral T-cell lymphoma.
Synonyms: (2E)-N-HYDROXY-3-(3-(PHENYLSULFAMOYL)PHENYL)PROP-2-ENAMIDE, N-Hydroxy-3-[3-(phenylsulfamoyl)phenyl]prop-2-enamideCategories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2A6 Substrates with a Narrow Therapeutic IndexDiabetes Mellitus
go.drugbank.com/conditions/DBCOND0027886Drugs: Ammonium chloride · Borneol · Insulin aspart · Insulin degludec · Insulin glargine · Insulin glulisine +4 moreSynonyms: Ketoacidosis in diabetes mellitusInsomnia
go.drugbank.com/conditions/DBCOND0017531Drugs: Amitriptyline · Brotizolam · Butabarbital · Cinolazepam · Clotiazepam · Daridorexant +31 moreSynonyms: Difficulty in sleep initiationSerdexmethylphenidate
go.drugbank.com/drugs/DB16629Approved[A230698, A230708] Serdexmethylphenidate is a prodrug of the CNS stimulant [dexmethylphenidate], a common first-line treatment for ADHD, that is combined with [dexmethylphenidate] to provide extended plasma … [L32298, L32323] Serdexmethylphenidate was granted FDA approval on March 2, 2021, and is currently marketed as a combination capsule with [dexmethylphenidate] under the trademark AZSTARYS™ by KemPharm
Amivantamab
go.drugbank.com/drugs/DB16695ApprovedInvestigational[A235133] Amivantamab was granted FDA approval on 21 May 2021,[L34193] followed by the approval by the EMA on 9 December 2021 [L41474] and Health Canada on 30 March 2022. … [A235103,A235123] Patients with NSCLC with exon 20 insertion mutations in EGFR do not respond to tyrosine kinase inhibitors, and were generally treated with platinum-based therapy.
Biotin
go.drugbank.com/drugs/DB00121ApprovedInvestigationalNutraceuticalA water-soluble, enzyme co-factor present in minute amounts in every living cell. It occurs mainly bound to proteins or polypeptides and is abundant in liver, kidney, pancreas, yeast, and milk.
Mixtures: Multi II IV Vi Tab, Multi Plex I - TabCategories: Vitamin B Complex, Heterocyclic Compounds, 1-RingTranscription factor p65
go.drugbank.com/bio_entities/BE0005551TargetHumansNF-kappa-B complexes are held in the cytoplasm in an inactive state complexed with members of the NF-kappa-B inhibitor (I-kappa-B) family. … Essential for cytokine gene expression in T-cells (PubMed:15790681). The NF-kappa-B homodimeric RELA-RELA complex appears to be involved in invasin-mediated activation of IL-8 expression.
Synonyms: Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3