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Clobetasol propionate Action Pathway
smpdb.ca/view/SMP0126191Drug actionClobetasol propionate is a corticosteroid derived from prednisolone but with a higher specificity for glucocorticoid receptors than mineralocorticoid receptors.
Drugs: Glutathione · Dinoprostone · Clobetasol propionate · Calcium · Prostaglandin D2 · Mesoheme +2 moreIcosapent Prostaglandin G/H synthase 1 and 2 anti-inflammatory Action Pathway
smpdb.ca/view/SMP0126557Drug actionIt is mostly found in fish oils. A diet rich in this molecule can be used/started to lower elevated triglycerides level in patients who are hyperglyceridimic.
Pterine Biosynthesis
smpdb.ca/view/SMP0000005MetabolicFolates are very important cofactors that provide support for many biosynthetic reactions. The reactions depicted in this pathway include reactions that are paired with transports, within the cell, travelling intracellularly, which allow...
beta-Alanine Metabolism
smpdb.ca/view/SMP0000007MetabolicBeta-alanine, 3-aminopropanoic acid, is a non-essential amino acid. Beta-Alanine is formed by the proteolytic degradation of beta-alanine containing dipeptides: carnosine, anserine, balenine, and pantothenic acid (vitamin B5). These dipe...
Cysteine Metabolism
smpdb.ca/view/SMP0000013MetabolicThe semi-essential amino aid cysteine is tightly regulated in the body to ensure proper levels for metabolism but maintaining levels below toxic thresholds. Cysteine can be obtained from diet or synthesized from O-acetyl-L-serine. Cystin...
Drugs: Pyridoxal phosphate · Pyruvic acid · Adenosine phosphate · Glutamic acid · Cysteine · NADH +6 morePhospholipid Biosynthesis
smpdb.ca/view/SMP0000025MetabolicThis pathway describes the synthesis of the common phospholipids, including phosphatidylcholine, phosphatidylethanolamine, phosphatidylserine, phosphatidylinositol and cardiolipins. Phospholipid synthesis is mediated by two possible mech...
Drugs: Choline · Phosphatidyl serine · NADH · Calcium · Magnesium cation · sn-glycerol 3-phosphate +5 moreOxidation of Branched-Chain Fatty Acids
smpdb.ca/view/SMP0000030MetabolicIn the majority of organisms, fatty acid degradation occurs mostly through the beta-oxidation cycle. In plants, this cycle only happens in the peroxisome, while in mammals this cycle happens in both the peroxisomes and mitochondria. Unfo...
Nicotinate and Nicotinamide Metabolism
smpdb.ca/view/SMP0000048MetabolicNicotinate (niacin) and nicotinamide - more commonly known as vitamin B3 - are precursors of the coenzymes nicotinamide-adenine dinucleotide (NAD+) and nicotinamide-adenine dinucleotide phosphate (NADP+). NAD+ synthesis occurs either de ...
Purine Metabolism
smpdb.ca/view/SMP0000050MetabolicPurine is a water soluble, organic compound. Purines, including purines that have been substituted, are the most widely distributed kind of nitrogen-containing heterocycle in nature. The two most important purines are adenine and guanine...
Drugs: Tetrahydrofolic acid · Aspartic acid · L-Glutamine · Adenosine phosphate · Glutamic acid · Glycine +24 morePyruvate Metabolism
smpdb.ca/view/SMP0000060MetabolicPyruvate is an intermediate compound in the metabolism of fats, proteins, and carbohydrates. It can be formed from glucose via glycolysis or the transamination of alanine. It can be converted into Acetyl-CoA to be used as the primary ene...