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Displaying results 11 - 15 of 15 in total
  1. Pathway

    Misoprostol Action Pathway

    smpdb.ca/view/SMP0124718
    Drug action

    Misoprostol may also promote ulcer healing by increasing mucus and bicarbonate secretion and thickening the mucosal bilayer so the mucosa can generate new cells. … With reduced protein kinase A activation, this decreases the activity of the proton pump, fewer H+ ions are pumped into the lumen, reducing the acidity and thus allowing stomach ulcers to heal and reducing

    Drugs: ATP · Misoprostol · Potassium cation · Magnesium cation · Zinc · Cyclic adenosine monophosphate +1 more
    Enzymes: Chloride anion exchanger
  2. Pathway

    Disulfiram Action Pathway

    smpdb.ca/view/SMP0000429
    Drug action

    Disulfiram is a drug used in the treatment of cocaine addiction and chronic alcoholism. … This causes more dopamine to accumulate in the axon terminal and more dopamine is released.

    Drugs: Pyridoxal phosphate · Ademetionine · Ascorbic acid · Aspartic acid · Adenosine phosphate · Tyrosine +27 more
  3. Pathway

    Magnesium Sulfate Action Pathway

    smpdb.ca/view/SMP0126350
    Drug action

    A small colorless crystal used as an anticonvulsant, a cathartic, and an electrolyte replenisher in the treatment of pre-eclampsia and eclampsia. … It is essential for the activity of many enzyme systems and plays an important role with regard to neurochemical transmission and muscular excitability.

    Drugs: Choline · ATP · Magnesium sulfate · Potassium cation · Calcium · Magnesium cation +3 more
  4. Pathway

    Neostigmine Action Pathway (new)

    smpdb.ca/view/SMP0126669
    Drug action

    The sodium causes depolarization of the cell, opening voltage-gated calcium channels on the sarcoplasmic reticulum. Calcium enters the cytosol from the sarcoplasmic reticulum and binds to calmodulin. … Nicotinic receptors are cation channels, when activated they transport sodium ions into the motor end plate.

    Drugs: Choline · Calcium · Magnesium cation · Neostigmine · Acetylcholine · Acetic acid
  5. Pathway

    Diamorphine Action Pathway

    smpdb.ca/view/SMP0125174
    Drug action

    causes sodium to leave the neuron. … It is a pro-drug for morphine and 6-MAM which means diamorphine doesn't act on opioid receptors itself, and instead synthesizes morphine and 6-acetylmorphine (6-MAM) which act on mu-opioid receptors, as

    Drugs: ATP · Morphine · Calcium · Magnesium cation · Diamorphine · Cyclic adenosine monophosphate +3 more