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Purine Metabolism
smpdb.ca/view/SMP0000050MetabolicPurine is a water soluble, organic compound. Purines, including purines that have been substituted, are the most widely distributed kind of nitrogen-containing heterocycle in nature. The two most important purines are adenine and guanine...
Drugs: Tetrahydrofolic acid · Aspartic acid · L-Glutamine · Adenosine phosphate · Glutamic acid · Glycine +24 moreFatty Acid Metabolism
smpdb.ca/view/SMP0000051MetabolicFatty acids constitute a large energy source for the body. The cellular membrane is also made up of fatty acids. During starvation times, fatty acids can provide energy to humans for numerous days. Fatty acid metabolism is also known as ...
Drugs: Adenosine phosphate · NADH · ATP · Levocarnitine · Magnesium cation · Flavin adenine dinucleotide +2 morePyruvate Metabolism
smpdb.ca/view/SMP0000060MetabolicPyruvate is an intermediate compound in the metabolism of fats, proteins, and carbohydrates. It can be formed from glucose via glycolysis or the transamination of alanine. It can be converted into Acetyl-CoA to be used as the primary ene...
Tryptophan Metabolism
smpdb.ca/view/SMP0000063MetabolicThis pathway depicts the metabolic reactions and pathways associated with tryptophan metabolism in animals. Tryptophan is an essential amino acid. This means that it cannot be synthesized by humans and other mammals and therefore must be...
Drugs: Pyridoxal phosphate · Ademetionine · Adenosine phosphate · Glutamic acid · Tryptophan · NADH +18 moreAspartate Metabolism
smpdb.ca/view/SMP0000067MetabolicAspartate is synthesized by transamination of oxaloacetate by aspartate aminotransferase or amino acid oxidase. Aspartyl-tRNA synthetase can then couple aspartate to aspartyl tRNA for protein synthesis. The aspartate content in human pro...
Drugs: Pyridoxal phosphate · Arginine · Aspartic acid · L-Glutamine · Adenosine phosphate · Glutamic acid +13 moreButyrate Metabolism
smpdb.ca/view/SMP0000073MetabolicButyrate metabolism (Butanoate metabolism) describes the metabolic fate of a number of short chain fatty acids or short chain alcohols that are typically produced by intestinal fermentation. Many of these molecules are eventually used in...
Drugs: Adenosine phosphate · Succinic acid · NADH · ATP · Magnesium cation · Acetoacetic acid +3 moreIbandronate Action Pathway
smpdb.ca/view/SMP0000079Drug actionThe action of ibandronate on bone tissue is based partly on its affinity for hydroxyapatite, which is part of the mineral matrix of bone. Nitrogen-containing bisphosphonates (such as pamidronate, alendronate, risedronate, ibandronate and...
Drugs: Cholecalciferol · ATP · Ibandronate · Magnesium cation · Iron · Dimethylallyl Diphosphate +9 morePravastatin Action Pathway
smpdb.ca/view/SMP0000089Drug actionPravastatin inhibits cholesterol synthesis via the mevalonate pathway by inhibiting 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase. HMG-CoA reductase is the enzyme responsible for the conversion of HMG-CoA to mevalonic acid, t...
Drugs: Cholecalciferol · ATP · Pravastatin · Magnesium cation · Iron · Dimethylallyl Diphosphate +9 moreRosuvastatin Action Pathway
smpdb.ca/view/SMP0000092Drug actionRosuvastatin, sold as Crestor, Rosulip and Zuvamor, belongs to the class of drugs known as statins. It is taken orally to inhibit the endogenous production of cholesterol in the liver. Statins do this by inhibiting the enzyme 3-hydroxy-3...
Drugs: Cholecalciferol · ATP · Rosuvastatin · Magnesium cation · Iron · Dimethylallyl Diphosphate +9 moreRisedronate Action Pathway
smpdb.ca/view/SMP0000112Drug actionRisedronate (also named Actonel, Atelvia or Benet.) is a type of medication that used to treat numbers of bone diseases because of its affinity for hydroxyapatite. Risedronate targets farnesyl pyrophosphate (FPP) synthase by inhibiting t...
Drugs: Cholecalciferol · ATP · Risedronic acid · Magnesium cation · Iron · Dimethylallyl Diphosphate +9 more