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Displaying results 2381 - 2390 of 8974 in total
  1. Drug

    Butamben

    go.drugbank.com/drugs/DB11148
    ApprovedWithdrawn

    Due to its very low water solubility, butamben is considered to be suitable only for topical anesthesia. … [A27147] Its structure corresponds to the standard molecule of a hydrophilic and hydrophobic domain separated by an intermediate ester found in most of the local anesthetics.

  2. Drug

    Nabilone

    go.drugbank.com/drugs/DB00486
    ApprovedInvestigational

    Nabilone is approved by the FDA for the treatment of nausea and vomiting associated with cancer chemotherapy in patients who have failed to respond adequately to conventional antiemetic treatments [FDA … It was approved in 1985 by the United States FDA for treatment of chemotherapy-induced nausea and vomiting that has not responded to conventional antiemetics.

  3. Drug

    Linzagolix

    go.drugbank.com/drugs/DB17083
    ApprovedInvestigational

    [A253667] Linzagolix was approved for use in the European Union in June 2022 for the management of symptoms caused by uterine fibroids.[L43627] … [A253642,A253647] It is similar to other GnRH receptor antagonists like [cetrorelix], [relugolix], and [elagolix].

  4. Drug

    Vernakalant

    go.drugbank.com/drugs/DB06217
    ApprovedInvestigational

    Vernakalant was developed by Cardiome Pharma as as an antiarrhythmic drug intended for rapid conversion of atrial fibrillation to sinus rhythm. … It is an investigational drug under regulatory review by FDA.

  5. Drug

    Dolutegravir

    go.drugbank.com/drugs/DB08930
    ApprovedInvestigational

    [L1035] On November 21, 2017, dolutegravir, in combination with rilpivirine, was approved as part of the first complete treatment regimen with only two drugs for the treatment of adults with HIV-1 named … [A31342] Dolutegravir was developed by ViiV Healthcare and FDA-approved on August 12, 2013.

    Categories: Antivirals for Systemic Use, Antiinfectives for Systemic Use
  6. Drug

    Norgestrel

    go.drugbank.com/drugs/DB09389
    Approved

    Norgestrel is synthetic steroidal progestin that is used in combination with ethinyl estradiol for oral contraception. … Norgestrel is composed of a racemic mixture of two stereoisomers, dextronorgestrel and levonorgestrel. However, only the levorotary enantiomer ([levonorgestrel]) is biologically active.

    Mixtures: Lo/Ovral, Lo-ovral-28Categories: Hormonal Contraceptives for Systemic Use
  7. Drug

    Phenindamine

    go.drugbank.com/drugs/DB01619
    Approved

    Antihistamines such as phenindamine appear to compete with histamine for histamine H1- receptor sites on effector cells. … It is used to treat sneezing, runny nose, itching, watery eyes, hives, rashes, itching, and other symptoms of allergies and the common cold.

    Categories: Antihistamines for Systemic Use
  8. Indication

    Dental Caries Extending Into Dentine

    go.drugbank.com/conditions/DBCOND0061100
    Drugs: Hydrogen fluoride · Olaflur · Sodium bicarbonate · Sodium fluoride
    Synonyms: Dental caries confined to enamel and dentine
  9. Indication

    Seborrheic Dermatitis

    go.drugbank.com/conditions/DBCOND0036095
    Drugs: Coal tar · Flutrimazole · Gentamicin · Ketoconazole · Levomenthol · Miconazole +8 more
    Synonyms: Greasy skin due to excessive secretion of sebum (disorder)
  10. Indication

    Substance Addiction

    go.drugbank.com/conditions/DBCOND0033529
    Drugs: Valpromide
    Synonyms: Addiction to drugs