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Displaying results 71 - 80 of 130 in total
  1. Pathway

    Naltrexone Action Pathway

    smpdb.ca/view/SMP0000687
    Drug action

    Naltrexone (also known as ReVia and Vivitrol) is a competitive antagonist of mu-type opioid receptor in the central nervous system (CNS). Naltrexone is also a type of medication that are used for manage opioid or alcohol dependence. Bind...

    Drugs: ATP · Norepinephrine · Naltrexone · Dopamine · Potassium cation · Calcium
  2. Pathway

    Dihydromorphine Action Pathway

    smpdb.ca/view/SMP0000689
    Drug action

    Dihydromorphine (also known as Paramorfan or Paramorphan) is analgesic that can bind to mu-type opioid receptor to activate associated G-protein in the sensory neurons of central nervous system (CNS), which will reduce the level of intra...

    Drugs: ATP · Norepinephrine · Dopamine · Potassium cation · Calcium · Dihydromorphine
  3. Pathway

    Ketobemidone Action Pathway

    smpdb.ca/view/SMP0000690
    Drug action

    Ketobemidone (also known as Ketogan) is analgesic that can bind to mu-type opioid receptor to activate associated G-protein in the sensory neurons of central nervous system (CNS), which will reduce the level of intracellular cAMP by inhi...

    Drugs: ATP · Norepinephrine · Dopamine · Potassium cation · Calcium · Ketobemidone
  4. Pathway

    Nalbuphine Action Pathway

    smpdb.ca/view/SMP0000691
    Drug action

    Nalbuphine (also known as Rubuphine and Nubain) is a competitive antagonist of mu-type and kappa-type opioid receptor in the central nervous system (CNS). Nalbuphine is also a type of medication that are mainly used for treat pain. Bindi...

    Drugs: ATP · Norepinephrine · Nalbuphine · Dopamine · Potassium cation · Calcium
  5. Pathway

    Methadyl Acetate Action Pathway

    smpdb.ca/view/SMP0000678
    Drug action

    Methadyl Acetate (also known as Acetylmethadol) is a synthetic opioid analgesic that can bind to mu-type opioid receptor to activate associated G-protein in the sensory neurons of central nervous system (CNS), which will reduce the level...

    Drugs: ATP · Norepinephrine · Dopamine · Potassium cation · Calcium · Methadyl acetate
  6. Pathway

    3-Methylthiofentanyl Action Pathway

    smpdb.ca/view/SMP0000679
    Drug action

    Methadyl Acetate (also known as Acetylmethadol) is analgesic that can bind to mu-type opioid receptor to activate associated G-protein in the sensory neurons of central nervous system (CNS), which will reduce the level of intracellular c...

    Drugs: ATP · Norepinephrine · Dopamine · Potassium cation · Calcium · 3-Methylthiofentanyl
  7. Pathway

    Caffeine Cardiac Contraction Action Pathway

    smpdb.ca/view/SMP0126520
    Drug action

    The antagonism of adenosine A1 receptors allows more norepinephrine to be released into the synapse where it causes contractions of the heart muscles through the norepinephrine subpathway. … Adenosine A1 receptors inhibit the release of catecholamines like norepinephrine from neurons that innervate the heart muscles.

    Drugs: Ascorbic acid · ATP · Caffeine · Norepinephrine · Dopamine · Calcium +1 more
  8. Pathway

    Pseudoephedrine Action Pathway

    smpdb.ca/view/SMP0125255
    Drug action

    Pseudoephedrine also inhibits sodium dependent noradrenaline receptors which prevents the reuptake of norepinephrine into the presynaptic neuron. … This causes norepinephrine to accumulate in the synapse which also activates alpha adrenergic receptors. These receptors then activate the Gq protein cascade.

    Drugs: Ascorbic acid · Norepinephrine · Pseudoephedrine · Dopamine · Calcium · Magnesium cation +1 more
  9. Pathway

    Droxidopa B2-Adrenergic Artery Dilation Action Pathway

    smpdb.ca/view/SMP0126493
    Drug action

    Droxidopa is an orally active synthetic precursor of norepinephrine that increases the deficient supply of norepinephrine in patients with NOH, thereby improving orthostatic blood pressure and alleviating … Norepinephrine binds to the beta-2 adrenergic receptor, the G protein signalling cascade begins.

    Drugs: ATP · Norepinephrine · Potassium cation · Calcium · Magnesium cation · Cyclic adenosine monophosphate
  10. Drug

    Phendimetrazine

    go.drugbank.com/drugs/DB01579
    ApprovedIllicit

    Phendimetrazine is a weight loss medication. Phendimetrazine is chemically related to amphetamines and is a Schedule III drug under the Convention on Psychotropic Substances and in the US since 1970.