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Displaying results 941 - 950 of 10000 in total
  1. Target

    SPARC

    go.drugbank.com/bio_entities/BE0002145
    TargetHumans

    Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites;...

    Synonyms: Secreted protein acidic and rich in cysteine
  2. Indication

    Sloughing Skin

    go.drugbank.com/conditions/DBCOND0111504
    Drugs: Phentolamine
    Synonyms: Changes in skin texture
  3. Indication

    Traveler's Diarrhea

    go.drugbank.com/conditions/DBCOND0040361
    Drugs: Azithromycin · Bismuth subsalicylate · Loperamide · Norfloxacin · Ofloxacin · Rifaximin
    Synonyms: Acute Gastroenteritis in Adult Travelers
  4. Target

    Cell growth-regulating nucleolar protein

    go.drugbank.com/bio_entities/BE0008958
    TargetMouse

    Prevents NCL self-cleavage, maintaining a normal steady-state level of NCL protein in undifferentiated embryonic stem cells (ESCs), which in turn is essential for ESC self-renewal (PubMed:19489080). … In addition, inhibits NF-kappa-B-mediated expression of pro-inflammatory cytokines (By similarity).

    Synonyms: Protein expressed in male leptotene and zygotene spermatocytes 264
  5. Target

    Serine/threonine-protein kinase Nek3

    go.drugbank.com/bio_entities/BE0009497
    TargetHumans

    Regulates microtubule acetylation in neurons. Contributes to prolactin-mediated phosphorylation of PXN and VAV2. … Implicated in prolactin-mediated cytoskeletal reorganization and motility of breast cancer cells through mechanisms involving RAC1 activation and phosphorylation of PXN and VAV2

    Synonyms: Never in mitosis A-related kinase 3
  6. Indication

    Back pain

    go.drugbank.com/conditions/DBCOND0115953
    Drugs: Acetaminophen · Borneol · Camphor · Capsaicin · Choline salicylate · Chondroitin sulfate +11 more
    Synonyms: Pain in back
  7. Drug

    Levetiracetam

    go.drugbank.com/drugs/DB01202
    ApprovedInvestigational

    It was first approved for use in the United States in 1999 and is structurally and mechanistically unrelated to other anti-epileptic drugs (AEDs). … a desirable choice over other AEDs, a class of drugs notorious for having generally narrow therapeutic indexes and a propensity for involvement in drug interactions.

    Products: Levetiracetam in Sodium Chloride, LIBERKETI-IV
  8. Drug

    Isopropyl alcohol

    go.drugbank.com/drugs/DB02325
    ApprovedInvestigational

    An isomer of 1-propanol. It is a colorless liquid having disinfectant properties. It is used in the manufacture of acetone and its derivatives and as a solvent. Topically, it is used as an antiseptic.

    Mixtures: BRAUNODERM (IN 250ML AND 1000ML PLASTIC), Ic-gelCategories: Compounds used in a research, industrial, or household setting
  9. Target

    Inactive phospholipase C-like protein 1

    go.drugbank.com/bio_entities/BE0001081
    TargetHumans

    Component in the phospho-dependent endocytosis process of GABA A receptor (By similarity). … Involved in an inositol phospholipid-based intracellular signaling cascade. Shows no PLC activity to phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol.

    Synonyms: Phospholipase C-deleted in lung carcinoma
  10. Drug

    Mirtazapine

    go.drugbank.com/drugs/DB00370
    ApprovedInvestigational

    [A178144,L6160] In addition to its beneficial effects in depression, mirtazapine has been reported to be efficacious in the off-label management of various other conditions. … Mirtazapine is a tetracyclic _piperazino-azepine_ antidepressant agent that was initially approved for the treatment of major depressive disorder (MDD) in the Netherlands in 1994.

    Products: REMERON IV, MİTAZEN 15 MG/5 ML IV İNFÜZYON İÇİN KONSANTRE ÇÖZELTİ İÇEREN AMPUL, 12 AMPUL