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Tafluprost

go.drugbank.com/drugs/DB08819
Approved

A prostaglandin analogue ester prodrug used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. Chemically, tafluprost is a fluorinated analog of prostaglandin F2-alpha. Tafluprost was approved for use in the U.S. on February 10, 2012.

  1. Pathway

    Tafluprost Action Pathway

    smpdb.ca/view/SMP0175201
    Drug action

    Tafluprost stimulates prostaglandin receptors on parietal cells in the stomach to reduce gastric acid secretion. Tafluprost activates prostaglandin EP3 receptors in parietal cells. … Tafluprost is a prostaglandin E1 analog that reduces the risk of NSAID-induced gastric ulcers.

    Drugs: ATP · Potassium cation · Magnesium cation · Zinc · Cyclic adenosine monophosphate · Pyrophosphoric acid +1 more
  2. Indication

    Ocular Hypertension

    go.drugbank.com/conditions/DBCOND0074237
    Drugs: Apraclonidine · Brimonidine · Dorzolamide · Glycerin · Latanoprost · Levobunolol +6 more
  3. Indication

    Increased Intra Ocular Pressure (IOP)

    go.drugbank.com/conditions/DBCOND0049485
    Drugs: Betaxolol · Bimatoprost · Brimonidine · Brinzolamide · Carbamoylcholine · Carteolol +11 more