Displaying drugs 3176 - 3200 of 12063 in total
Flortaucipir F-18
Flortaucipir F-18, also known as 18F-T807 and 18F-AV-1451, is a small indole molecule synthesized with a radioactive fluorine isotope. It is used as a marker in positron emission tomography (PET) imaging of patients suspected of having Alzheimer's disease. After crossing the blood-brain barrier, flortaucipir F-18 binds to aggregated tau protein,...
Approved
Investigational
Matched Description: … synthesized with a radioactive fluorine isotope. ... Flortaucipir F-18, also known as 18F-T807 and 18F-AV-1451, is a small indole molecule ... [A203933] It is used as a marker in positron emission tomography (PET) imaging of patients suspected …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Venetoclax
Venetoclax is a BCL-2 inhibitor that was initially approved by the FDA in April 2016 [FDA label]. Proteins in the B cell CLL/lymphoma 2 (BCL-2) family are important regulators of the apoptotic (programmed cell death) process , . Venetoclax is used to treat chronic lymphocytic leukemia (CLL) and certain types...
Approved
Investigational
Matched Description: … Venetoclax is a BCL-2 inhibitor that was initially approved by the FDA in April 2016 [FDA label]. ... A new indication was approved in 2018 for the treatment patients with chronic lymphocytic leukemia (CLL …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Coagulation factor X human
Coagulation Factor X (Human), is a plasma-derived human blood coagulation factor is used by adults and children (aged 12 years and above) with hereditary Factor X deficiency. However its use is limited in the perioperative setting for the management of bleeding in major surgery in patients with moderate and severe...
Approved
Investigational
Matched Description: … Coagulation Factor X (Human), is a plasma-derived human blood coagulation factor is used by adults and ... It is a two-chain glycoprotein with the molecular weight of approximately 59 kDa [A31472]. ... Coagulation Factor X is a vitamin K-dependent, liver-produced serine protease that serves as the first …
Aluminum sulfate
Aluminum (Al), also spelled aluminum, chemical element, a lightweight, silvery-white metal of main Group 13 (IIIa, or boron group) of the periodic table .
It is a chemical agent used in water purification, the pH regulation of garden soil, and other commercial or industrial applications. Medically, it is primarily used...
Approved
Matched Description: … It most commonly exists in a combined state with various other elements. ... Aluminum (Al), also spelled aluminum, chemical element, a lightweight, silvery-white metal of main Group ... It is a chemical agent used in water purification, the pH regulation of garden soil, and other commercial …
Pipecuronium
Pipecuronium is a piperazinyl androstane derivative which is a non-depolarizing neuromuscular blocking agent.
Approved
Matched Iupac: … 1,7-bis(acetyloxy)-8-(4,4-dimethylpiperazin-4-ium-1-yl)-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a] …
Matched Description: … Pipecuronium is a piperazinyl androstane derivative which is a non-depolarizing neuromuscular blocking …
Matched Description: … Pipecuronium is a piperazinyl androstane derivative which is a non-depolarizing neuromuscular blocking …
Desoxycorticosterone acetate
Approved
Matched Iupac: … 9aR,9bS,11aS)-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Pancuronium
A bis-quaternary steroid that is a competitive nicotinic antagonist. As a neuromuscular blocking agent it is more potent than curare but has less effect on the circulatory system and on histamine release.
Approved
Matched Iupac: … 11aS)-1,7-bis(acetyloxy)-9a,11a-dimethyl-8-(1-methylpiperidin-1-ium-1-yl)-hexadecahydro-1H-cyclopenta[a] …
Matched Description: … A bis-quaternary steroid that is a competitive nicotinic antagonist. ... As a neuromuscular blocking agent it is more potent than curare but has less effect on the circulatory …
Matched Description: … A bis-quaternary steroid that is a competitive nicotinic antagonist. ... As a neuromuscular blocking agent it is more potent than curare but has less effect on the circulatory …
Phleum pratense pollen
Phleum pratense pollen allergenic extract is used in allergenic testing.
Approved
Investigational
Matched Mixtures name: … SLITone ULTRA D. glomerata/ L. perenne/ P. pratense/ P. pratensis/ A. odoratum …
Acetophenazine
Acetophenazine is an antipsychotic drug of moderate-potency. It is used in the treatment of disorganized and psychotic thinking. It is also used to help treat false perceptions (e.g. hallucinations or delusions). It primarily targets the dopamine D2 receptor.
Approved
Lumasiran
Lumasiran is a small interfering RNA used in the treatment of primary hyperoxaluria type 1 (PH1). This condition, caused by a deficiency in the enzyme alanine-glyoxylate aminotransferase, leads to an accumulation of oxalate, causing calcium crystal formation. These patients experience frequent kidney stones, nephrocalcinosis, and renal failure. Oxlumo, producted by...
Approved
Investigational
Matched Description: … Lumasiran is a small interfering RNA used in the treatment of primary hyperoxaluria type 1 (PH1). ... [L23554] This condition, caused by a deficiency in the enzyme alanine-glyoxylate aminotransferase, leads …
Dronedarone
Dronedarone is a Class III antiarrhythmic drug that works to restore the normal sinus rhythm in patients with paroxysmal or persistent atrial fibrillation. Atrial fibrillation is a common sustained arrhythmia where the treatment primarily focuses on stroke prevention and symptom management. It is managed by rate control, rhythm control, prevention...
Approved
Matched Description: … Dronedarone is a Class III antiarrhythmic drug that works to restore the normal sinus rhythm in patients ... Atrial fibrillation is a common sustained arrhythmia where the treatment primarily focuses on stroke ... [A34604] Similar to [amiodarone], dronedarone is a multichannel blocker that works to control rhythm …
Matched Categories: … Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A5 Substrates with a Narrow Therapeutic Index …
Matched Categories: … Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A5 Substrates with a Narrow Therapeutic Index …
Quinapril
Quinapril is the ethyl ester prodrug of the non-sulfhydryl angiotensin converting enzyme inhibitor quinaprilat.[L8420,L8423] It is used to treat hypertension and heart failure.[L8420,L8423] ACE inhibitors are commonly used as a first line therapy in the treatment of hypertension, along with thiazide diuretics or beta blockers. Quinapril was granted FDA approval...
Approved
Investigational
Matched Description: … [L8420] A combination tablet with [hydrochlorothiazide] was also approved on 28 December 1999. ... [L8420,L8423] ACE inhibitors are commonly used as a first line therapy in the treatment of hypertension …
Gadoteridol
Gadoteridol is a macrocyclic nonionic gadolinium that provides contrast enhancement of the brain, spine, and surrounding tissues, resulting in improved visualization (compared with unenhanced MRI) of lesions with abnormal vascularity or those thought to disrupt the normal blood-brain barrier.[A263076,A263081,L49871] It was 1 of the 3 macrocyclic gadolinium-based contrast agents (GBCAs)...
Approved
Investigational
Matched Description: … Gadoteridol is a macrocyclic nonionic gadolinium that provides contrast enhancement of the brain, spine …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Probucol
A drug used to lower LDL and HDL cholesterol yet has little effect on serum-triglyceride or VLDL cholesterol. (From Martindale, The Extra Pharmacopoeia, 30th ed, p993).
Approved
Investigational
Matched Description: … A drug used to lower LDL and HDL cholesterol yet has little effect on serum-triglyceride or VLDL cholesterol …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Laurocapram
Approved
Fusarium compactum
Fusarium compactum is a fungus which can provoke allergic reactions. Fusarium compactum extract is used in allergenic testing.
Approved
Matched Description: … Fusarium compactum is a fungus which can provoke allergic reactions. …
Pregnenolone
A 21-carbon steroid, derived from cholesterol and found in steroid hormone-producing tissues. Pregnenolone is the precursor to gonadal steroid hormones and the adrenal corticosteroids.
Approved
Experimental
Matched Iupac: … 9bS,11aS)-7-hydroxy-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,6H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … A 21-carbon steroid, derived from cholesterol and found in steroid hormone-producing tissues. …
Matched Description: … A 21-carbon steroid, derived from cholesterol and found in steroid hormone-producing tissues. …
Fluprednisolone
A synthetic glucocorticoid with anti-inflammatory properties.
Approved
Matched Iupac: … dihydroxy-1-(2-hydroxyacetyl)-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … A synthetic glucocorticoid with anti-inflammatory properties. …
Matched Description: … A synthetic glucocorticoid with anti-inflammatory properties. …
Testosterone enantate benzilic acid hydrazone
Approved
Experimental
Matched Iupac: … diphenylacetamido)imino]-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Loteprednol etabonate
Loteprednol Etabonate (LE) is a topical corticoid anti-inflammatory. It is used in ophthalmic solution for the treatment of steroid responsive inflammatory conditions of the eye such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitides. As a nasal spray, it can...
Approved
Matched Iupac: … ethoxycarbonyl)oxy]-10-hydroxy-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … Loteprednol Etabonate (LE) is a topical corticoid anti-inflammatory. ... As a nasal spray, it can be used for the treatment and management of seasonal allergic rhinitis. ... A number of such new formulations that have been approved include Kala Pharmaceutical's Inveltys - the …
Matched Description: … Loteprednol Etabonate (LE) is a topical corticoid anti-inflammatory. ... As a nasal spray, it can be used for the treatment and management of seasonal allergic rhinitis. ... A number of such new formulations that have been approved include Kala Pharmaceutical's Inveltys - the …
Prednisolone acetate
Prednisolone acetate is a prednisolone molecule bound to an acetate functional group by an ester bond. Prednisolone acetate was granted FDA approval in 1955.
Approved
Vet approved
Matched Iupac: … 11aS)-1,10-dihydroxy-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … Prednisolone acetate is a [prednisolone] molecule bound to an acetate functional group by an ester bond …
Matched Description: … Prednisolone acetate is a [prednisolone] molecule bound to an acetate functional group by an ester bond …
Alosetron
Alosetron is a 5-HT3 antagonist used only for the management of severe diarrhoea-predominant irritable bowel syndrome (IBS) in women. Alosetron has an antagonist action on the 5-HT3 receptors and thus may modulate serotonin-sensitive gastrointestinal (GI) processes. Alosetron was voluntarily withdrawn from the US market in November 2000 by the manufacturer...
Approved
Withdrawn
Matched Description: … Alosetron is a 5-HT3 antagonist used only for the management of severe diarrhoea-predominant irritable ... In June 2002, the FDA approved a supplemental new drug application allowing the remarketing of the drug …
Amifampridine
Amifampridine, or 3,4-diaminopyridine (3,4-DAP), is a quaternary ammonium compound that blocks presynaptic potassium channels, and subsequently prolongs the action potential and increases presynaptic calcium concentrations . It was first discovered in Scotland in the 1970s and its clinical effectiveness for neuromuscular disorders, including Lambert–Eaton myasthenic syndrome (LEMS), has been investigated...
Approved
Investigational
Matched Description: … Amifampridine, or 3,4-diaminopyridine (3,4-DAP), is a quaternary ammonium compound that blocks presynaptic ... for LEMS in adult patients and is ideally given as oral tablets in divided doses, three or four times a ... Amifampridine phosphate is a more stable salt that serves as an active ingredient of EMA-approved Firdapse …
Retapamulin
Retapamulin, marketed by GlaxoSmithKline as the ointment Altabax, is an antibiotic for skin infections like impetigo. It was approved by the FDA in April 2007.
Approved
Displaying drugs 3176 - 3200 of 12063 in total