Displaying drugs 15351 - 15375 of 15521 in total
Staurosporine
An indolocarbazole that is a potent protein kinase C inhibitor which enhances cAMP-mediated responses in human neuroblastoma cells. (Biochem Biophys Res Commun 1995;214(3):1114-20)
Experimental
Matched Iupac: … (2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1^{2,6}.0^{7,28 …
Matched Description: … An indolocarbazole that is a potent protein kinase C inhibitor which enhances cAMP-mediated responses ... in human neuroblastoma cells. ... (Biochem Biophys Res Commun 1995;214(3):1114-20) …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Heterocyclic Compounds, 3-Ring …
Matched Description: … An indolocarbazole that is a potent protein kinase C inhibitor which enhances cAMP-mediated responses ... in human neuroblastoma cells. ... (Biochem Biophys Res Commun 1995;214(3):1114-20) …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Heterocyclic Compounds, 3-Ring …
Robenidine
Robenidine is identified as a coccidiostat drug, which slows both the growth and reproductive cycles of coccidian parasites. Robenidine is used to control coccidiosis, a lethal infection in poultry which has shown a significant economic burden. Despite the availability of other agents to treat coccidiosis, robenidine has been proven to...
Experimental
Vet approved
Matched Iupac: … N,N'-bis[(E)-[(4-chlorophenyl)methylidene]amino]guanidine …
Matched Description: … Robenidine is used to control coccidiosis, a lethal infection in poultry which has shown a significant ... Robenidine is identified as a coccidiostat drug, which slows both the growth and reproductive cycles ... Despite the availability of other agents to treat coccidiosis, robenidine has been proven to be effective in …
Matched Description: … Robenidine is used to control coccidiosis, a lethal infection in poultry which has shown a significant ... Robenidine is identified as a coccidiostat drug, which slows both the growth and reproductive cycles ... Despite the availability of other agents to treat coccidiosis, robenidine has been proven to be effective in …
Magnesium orotate
Magnesium orotate is a magnesium salt of orotic acid and is poorly soluble in water. It is a source of magnesium and is used as a mineral supplement to treat Mg deficiency. Orotic acid acts as a transporter that carries magnesium into the cells. It also exhibits antioxidant properties, since...
Experimental
Matched Iupac: … magnesium(2+) ion bis(2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylate) …
Matched Description: … Magnesium orotate is a magnesium salt of orotic acid and is poorly soluble in water. ... It also exhibits antioxidant properties, since it is a key intermediate in the biosynthetic pathway of ... It is a source of magnesium and is used as a mineral supplement to treat Mg deficiency. …
Matched Description: … Magnesium orotate is a magnesium salt of orotic acid and is poorly soluble in water. ... It also exhibits antioxidant properties, since it is a key intermediate in the biosynthetic pathway of ... It is a source of magnesium and is used as a mineral supplement to treat Mg deficiency. …
LNP-nCoVsaRNA Vaccine
LNP-nCoVsaRNA is a purified, synthetic mRNA vaccine candidate encoding the S glycoprotein of SARS-CoV-2, which is used primarily by the virus to attach to and invade human cells. The vaccine was developed in and tested by the Medical Research Council Clinical Trials Unit at UCL in the UK, and jointly...
Investigational
Matched Description: … -2, which is used primarily by the virus to attach to and invade human cells. ... The vaccine was developed in and tested by the Medical Research Council Clinical Trials Unit at UCL in ... LNP-nCoVsaRNA is a purified, synthetic mRNA vaccine candidate encoding the S glycoprotein of SARS-CoV …
Nalorphine
Nalorphine is a mixed opioid agonist–antagonist. It acts at two opioid receptors—at the mu receptor it has antagonistic effects, and at the kappa receptors it exerts high-efficacy agonistic characteristics. It is used to reverse opioid overdose and (starting in the 1950s) in a challenge test to determine opioid dependence.
Experimental
Vet approved
Matched Iupac: … (1S,5R,13R,14S,17R)-4-(prop-2-en-1-yl)-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca …
Matched Description: … It is used to reverse opioid overdose and (starting in the 1950s) in a challenge test to determine opioid ... Nalorphine is a mixed opioid agonist–antagonist. …
Matched Description: … It is used to reverse opioid overdose and (starting in the 1950s) in a challenge test to determine opioid ... Nalorphine is a mixed opioid agonist–antagonist. …
Pritelivir
Pritelivir has been used in trials studying the prevention of HSV-2 and Genital Herpes.
Investigational
Matched Iupac: … N-methyl-N-(4-methyl-5-sulfamoyl-1,3-thiazol-2-yl)-2-[4-(pyridin-2-yl)phenyl]acetamide …
Matched Description: … Pritelivir has been used in trials studying the prevention of HSV-2 and Genital Herpes. …
Matched Description: … Pritelivir has been used in trials studying the prevention of HSV-2 and Genital Herpes. …
Riboprine
Ipa has been used in trials studying the treatment of Nausea and Surgical Site Infection.
Investigational
Matched Iupac: … (2R,3S,4R,5R)-2-(hydroxymethyl)-5-{6-[(3-methylbut-2-en-1-yl)amino]-9H-purin-9-yl}oxolane-3,4-diol …
Matched Description: … Ipa has been used in trials studying the treatment of Nausea and Surgical Site Infection. …
Matched Description: … Ipa has been used in trials studying the treatment of Nausea and Surgical Site Infection. …
TRV-120027
TRV120027 has been used in trials studying the treatment of Heart Failure and Kidney Disease.
Investigational
Matched Iupac: … ]pentanamido]-3-methylbutanamido]-3-(4-hydroxyphenyl)propanamido]-3-methylpentanamido]-3-(1H-imidazol ... (2R)-2-{[(2S)-1-[(2S)-2-[(2S,3S)-2-[(2S)-2-[(2S)-2-[(2S)-5-carbamimidamido-2-[2-(methylamino)acetamido ... -5-yl)propanoyl]pyrrolidin-2-yl]formamido}propanoic acid …
Matched Description: … TRV120027 has been used in trials studying the treatment of Heart Failure and Kidney Disease. …
Matched Description: … TRV120027 has been used in trials studying the treatment of Heart Failure and Kidney Disease. …
Balapiravir
Balapiravir has been used in trials studying the treatment of Dengue and Hepatitis C, Chronic.
Investigational
Matched Iupac: … -2-yl]methyl 2-methylpropanoate ... [(2R,3S,4R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-2-azido-3,4-bis[(2-methylpropanoyl)oxy]oxolan …
Matched Description: … Balapiravir has been used in trials studying the treatment of Dengue and Hepatitis C, Chronic. …
Matched Description: … Balapiravir has been used in trials studying the treatment of Dengue and Hepatitis C, Chronic. …
Bitopertin
Bitopertin has been used in trials studying the treatment of Schizophrenia and Obsessive-Compulsive Disorder.
Investigational
Matched Iupac: … 1-[3-fluoro-5-(trifluoromethyl)pyridin-2-yl]-4-(5-methanesulfonyl-2-{[(2S)-1,1,1-trifluoropropan-2-yl …
Matched Description: … Bitopertin has been used in trials studying the treatment of Schizophrenia and Obsessive-Compulsive Disorder …
Matched Description: … Bitopertin has been used in trials studying the treatment of Schizophrenia and Obsessive-Compulsive Disorder …
Piperine
Bioperine has been used in trials studying the treatment of Multiple Myeloma and Deglutition Disorders.
Investigational
Matched Description: … Bioperine has been used in trials studying the treatment of Multiple Myeloma and Deglutition Disorders …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
UK-432097
UK-432,097 has been used in trials studying the treatment of Pulmonary Disease, Chronic Obstructive.
Investigational
Matched Iupac: … (pyridin-2-yl)piperidin-4-yl]carbamoyl}amino)ethyl]-9H-purine-2-carboxamide ... 6-[(2,2-diphenylethyl)amino]-9-[(2R,3R,4S,5S)-5-(ethylcarbamoyl)-3,4-dihydroxyoxolan-2-yl]-N-[2-({[1- …
Matched Description: … UK-432,097 has been used in trials studying the treatment of Pulmonary Disease, Chronic Obstructive. …
Matched Categories: … Adenosine A receptor agonists ... Heterocyclic Compounds, 2-Ring …
Matched Description: … UK-432,097 has been used in trials studying the treatment of Pulmonary Disease, Chronic Obstructive. …
Matched Categories: … Adenosine A receptor agonists ... Heterocyclic Compounds, 2-Ring …
Nivocasan
Nivocasan has been used in trials studying the treatment of HCV Infection and Nonalcoholic Steatohepatitis.
Investigational
Matched Iupac: … (5R)-N-[(2S,3S)-2-(fluoromethyl)-2-hydroxy-5-oxooxolan-3-yl]-3-(isoquinolin-1-yl)-5-(propan-2-yl)-4,5 …
Matched Description: … Nivocasan has been used in trials studying the treatment of HCV Infection and Nonalcoholic Steatohepatitis …
Matched Description: … Nivocasan has been used in trials studying the treatment of HCV Infection and Nonalcoholic Steatohepatitis …
Pactimibe
Pactimibe has been used in trials studying the treatment of Atherosclerosis and Coronary Heart Disease.
Investigational
Matched Iupac: … 2-[7-(2,2-dimethylpropanamido)-4,6-dimethyl-1-octyl-2,3-dihydro-1H-indol-5-yl]acetic acid …
Matched Description: … Pactimibe has been used in trials studying the treatment of Atherosclerosis and Coronary Heart Disease …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Description: … Pactimibe has been used in trials studying the treatment of Atherosclerosis and Coronary Heart Disease …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Berkelium
Berkelium is under investigation in clinical trial NCT02189122 (Comparative Effects of Aspirin and NHP-544C).
Investigational
Matched Description: … Berkelium is under investigation in clinical trial NCT02189122 (Comparative Effects of Aspirin and NHP …
4-isothioureidobutyronitrile
Thioureidobutyronitrile has been used in trials studying the treatment of Solid Tumors and Ovarian cancer.
Investigational
Matched Description: … Thioureidobutyronitrile has been used in trials studying the treatment of Solid Tumors and Ovarian cancer …
Pruvanserin
Pruvanserin has been used in trials studying the treatment of Sleep Initiation and Maintenance Disorders.
Investigational
Matched Iupac: … 7-{4-[2-(4-fluorophenyl)ethyl]piperazine-1-carbonyl}-1H-indole-3-carbonitrile …
Matched Description: … Pruvanserin has been used in trials studying the treatment of Sleep Initiation and Maintenance Disorders …
Matched Description: … Pruvanserin has been used in trials studying the treatment of Sleep Initiation and Maintenance Disorders …
Tarloxotinib
Tarloxotinib is under investigation in clinical trial NCT03743350 (NSCLC Exon 20 or HER2-activating Mutations).
Investigational
Matched Iupac: … [(2E)-3-({4-[(3-bromo-4-chlorophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl}carbamoyl)prop-2-en-1-yl]dimethyl …
Matched Description: … Tarloxotinib is under investigation in clinical trial NCT03743350 (NSCLC Exon 20 or HER2-activating Mutations …
Matched Description: … Tarloxotinib is under investigation in clinical trial NCT03743350 (NSCLC Exon 20 or HER2-activating Mutations …
Mavoglurant
Mavoglurant has been used in trials studying the treatment of Patient Diagnosed With OCD and and Resistant to SSRI Treatment (Failed SSRI Over 12 Weeks at Appropriate Doses).
Investigational
Matched Iupac: … methyl (3aR,4S,7aR)-4-hydroxy-4-[2-(3-methylphenyl)ethynyl]-octahydro-1H-indole-1-carboxylate …
Matched Description: … Mavoglurant has been used in trials studying the treatment of Patient Diagnosed With OCD and and Resistant …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Description: … Mavoglurant has been used in trials studying the treatment of Patient Diagnosed With OCD and and Resistant …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Gevokizumab
Gevokizumab has been used in trials studying the treatment of Acne Vulgaris, Osteoarthritis, Behcet's Uveitis, Pyoderma Gangrenosum, and Behcet's Disease Uveitis, among others. Gevokizumab acts as a modulator of cytokine imbalance in IL-1 mediated disease states. It has a very high binding affinity of 300fM and blocks the activation of...
Investigational
Matched Description: … Gevokizumab acts as a modulator of cytokine imbalance in IL-1 mediated disease states. ... It has a very high binding affinity of 300fM and blocks the activation of IL-1 receptors. ... Gevokizumab has been used in trials studying the treatment of Acne Vulgaris, Osteoarthritis, Behcet's …
Berzosertib
Berzosertib (VX-970) has been used in trials studying the treatment of Ovarian Neoplasms, Ovarian Serous Tumor, Adult Solid Neoplasm, Advanced Solid Tumor, and Advanced Solid Neoplasm, among others.
Investigational
Matched Iupac: … 3-(3-{4-[(methylamino)methyl]phenyl}-1,2-oxazol-5-yl)-5-[4-(propane-2-sulfonyl)phenyl]pyrazin-2-amine …
Matched Description: … Berzosertib (VX-970) has been used in trials studying the treatment of Ovarian Neoplasms, Ovarian Serous …
Matched Description: … Berzosertib (VX-970) has been used in trials studying the treatment of Ovarian Neoplasms, Ovarian Serous …
Sonolisib
Sonolisib has been used in trials studying the treatment of Glioblastoma, Prostate Cancer, Advanced Solid Tumors, Advanced BRAF-mutant Cancers, and Non Small Cell Lung Cancer (NSCLC), among others.
Investigational
Matched Iupac: … (2R,3S,6E,11R,15S,17R)-6-{[bis(prop-2-en-1-yl)amino]methylidene}-8-hydroxy-3-(methoxymethyl)-2,15-dimethyl …
Matched Description: … Sonolisib has been used in trials studying the treatment of Glioblastoma, Prostate Cancer, Advanced Solid …
Matched Description: … Sonolisib has been used in trials studying the treatment of Glioblastoma, Prostate Cancer, Advanced Solid …
PF-06291874
PF-06291874 is under investigation in clinical trial NCT02175121 (Safety, Tolerability, Pharmacokinetics And Pharmacodynamics Study of PF-06291874 as Oral Monotherapy To Treat Adults With Type 2 Diabetes Mellitus).
Investigational
Matched Iupac: … 3-({4-[(1S)-1-{3,5-dimethyl-4-[4-(trifluoromethyl)-1H-pyrazol-1-yl]phenoxy}butyl]phenyl}formamido)propanoic …
Matched Description: … PF-06291874 is under investigation in clinical trial NCT02175121 (Safety, Tolerability, Pharmacokinetics ... And Pharmacodynamics Study of PF-06291874 as Oral Monotherapy To Treat Adults With Type 2 Diabetes Mellitus …
Matched Description: … PF-06291874 is under investigation in clinical trial NCT02175121 (Safety, Tolerability, Pharmacokinetics ... And Pharmacodynamics Study of PF-06291874 as Oral Monotherapy To Treat Adults With Type 2 Diabetes Mellitus …
Tofimilast
Tofimilast has been used in trials studying the treatment of Asthma and Pulmonary Disease, Chronic Obstructive.
Investigational
Matched Iupac: … 12-cyclopentyl-10-ethyl-5-(thiophen-2-yl)-3,4,6,11,12-pentaazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2,4,10 …
Matched Description: … Tofimilast has been used in trials studying the treatment of Asthma and Pulmonary Disease, Chronic Obstructive …
Matched Description: … Tofimilast has been used in trials studying the treatment of Asthma and Pulmonary Disease, Chronic Obstructive …
ORM-12741
ORM-12741 has been used in trials studying the basic science and treatment of Alzheimer's Disease.
Investigational
Matched Iupac: … (2S,3S)-3-(methoxymethyl)-3-methyl-17-oxa-7-azatetracyclo[8.7.0.0^{2,7}.0^{11,16}]heptadeca-1(10),11,13,15 …
Matched Description: … ORM-12741 has been used in trials studying the basic science and treatment of Alzheimer's Disease. …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Adrenergic alpha-2 Receptor Antagonists …
Matched Description: … ORM-12741 has been used in trials studying the basic science and treatment of Alzheimer's Disease. …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Adrenergic alpha-2 Receptor Antagonists …
Displaying drugs 15351 - 15375 of 15521 in total