Displaying drugs 651 - 675 of 5185 in total
Irinotecan
Irinotecan is a topoisomerase inhibitor used for chemotherapy. It is a water-soluble analogue of camptothecin, which is extracted from the Chinese tree Camptotheca acuminate. The bis-piperidine side chain in the structure of irinotecan bestows enhanced water solubility. As an anticancer drug, irinotecan was first commercially available in Japan in 1994...
Approved
Investigational
Matched Synonyms: … -9-yl 4-(2-(5-(3-(2,4-dihydroxy-5-isopropylphenyl)-5-hydroxy-4H-1,2,4-triazol-4-yl)-1H-indol-1-yl)ethyl ... )piperidine-1-carboxylate ... (S)-4,11-diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin …
Matched Iupac: … 21),2,4(9),5,7,10,15(20)-heptaen-7-yl [1,4'-bipiperidine]-1'-carboxylate ... diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.0^{2,11}.0^{4,9}.0^{15,20}]henicosa-1( …
Matched Categories: … Topoisomerase 1 (TOP1) inhibitors …
Matched Products: … TEKAMEN 40 MG/2 ML IV INFUZYON COZ.ICEREN 1 FLAKON ... IROTEN 40 MG/2 ML IV INFUZYONLUK KONSANTRE COZELTI, 1 ADET ... IRONTU 40 MG/2 ML IV INFUZYON ICIN COZELTI ICEREN FLAKON, 1 ADET …
Matched Iupac: … 21),2,4(9),5,7,10,15(20)-heptaen-7-yl [1,4'-bipiperidine]-1'-carboxylate ... diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.0^{2,11}.0^{4,9}.0^{15,20}]henicosa-1( …
Matched Categories: … Topoisomerase 1 (TOP1) inhibitors …
Matched Products: … TEKAMEN 40 MG/2 ML IV INFUZYON COZ.ICEREN 1 FLAKON ... IROTEN 40 MG/2 ML IV INFUZYONLUK KONSANTRE COZELTI, 1 ADET ... IRONTU 40 MG/2 ML IV INFUZYON ICIN COZELTI ICEREN FLAKON, 1 ADET …
Ceftaroline fosamil
Ceftaroline fosamil is a cephalosporin antibacterial indicated for the treatment of the following infections caused by designated susceptible bacteria:
Acute bacterial skin and skin structure infections.
Community-acquired bacterial pneumonia.
Approved
Investigational
Matched Synonyms: … (6R,7R)-7-[(2Z)-2-ethoxyimino-2-[5-(phosphonoamino)-1,2,4-thiadiazol-3-yl]acetyl]amino]-3-[4-(1-methylpyridin ... -1-ium-4-yl)-1,3-thiazol-2-yl]sulfanyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate …
Matched Iupac: … 4-(2-{[(6R,7R)-2-carboxylato-7-[(2Z)-2-(ethoxyimino)-2-[5-(phosphonoamino)-1,2,4-thiadiazol-3-yl]acetamido ... ]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]sulfanyl}-1,3-thiazol-4-yl)-1-methylpyridin-1-ium …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … 4-(2-{[(6R,7R)-2-carboxylato-7-[(2Z)-2-(ethoxyimino)-2-[5-(phosphonoamino)-1,2,4-thiadiazol-3-yl]acetamido ... ]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]sulfanyl}-1,3-thiazol-4-yl)-1-methylpyridin-1-ium …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Efavirenz
Efavirenz (brand names Sustiva® and Stocrin®) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) and is used as part of highly active antiretroviral therapy (HAART) for the treatment of a human immunodeficiency virus (HIV) type 1.
For HIV infection that has not previously been treated, efavirenz and lamivudine in combination with...
Approved
Investigational
Matched Synonyms: … 6-chloro-4-(2-cyclopropyl-1-ethynyl)-4-trifluoromethyl-(4S)-1,4-dihydro-2H-benzo[d][1,3]oxazin-2-one ... (S)-6-chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-benzo[d][1,3]oxazin-2-one ... (S)-6-chloro-4-(Cyclopropylethynyl)-1,4-dihydro-(S)-6-chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl …
Matched Iupac: … (4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-2,4-dihydro-1H-3,1-benzoxazin-2-one …
Matched Description: … active antiretroviral therapy (HAART) for the treatment of a human immunodeficiency virus (HIV) type 1. …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Heterocyclic Compounds, 1-Ring ... Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor …
Matched Iupac: … (4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-2,4-dihydro-1H-3,1-benzoxazin-2-one …
Matched Description: … active antiretroviral therapy (HAART) for the treatment of a human immunodeficiency virus (HIV) type 1. …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Heterocyclic Compounds, 1-Ring ... Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor …
Unoprostone
Unoprostone isopropyl is a prostaglandin analogue. Ophthalmic Solution 0.15% is a synthetic docosanoid. Unoprostone isopropyl has the chemical name isopropyl (+)-(Z)-7-[(1R,2R,3R,5S)-3,5 dihydroxy-2-(3-oxodecyl)cyclopentyl]-5-heptenoate.
The main indication of Unoprostane is treatment of glucoma.
Approved
Investigational
Matched Synonyms: … 13,14-dihydro-15-keto-20-ethyl PGF2α …
Matched Iupac: … (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-(3-oxodecyl)cyclopentyl]hept-5-enoic acid …
Matched Description: … Unoprostone isopropyl has the chemical name isopropyl (+)-(Z)-7-[(1R,2R,3R,5S)-3,5 dihydroxy-2-(3-oxodecyl …
Matched Salts cas: … 120373-24-2 …
Matched Iupac: … (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-(3-oxodecyl)cyclopentyl]hept-5-enoic acid …
Matched Description: … Unoprostone isopropyl has the chemical name isopropyl (+)-(Z)-7-[(1R,2R,3R,5S)-3,5 dihydroxy-2-(3-oxodecyl …
Matched Salts cas: … 120373-24-2 …
Cilostazol
Cilostazol is a quinolinone derivative and antiplatelet agent with vasodilating properties that has been used in the symptomatic treatment of intermittent claudication in patients with peripheral ischaemia. It is marketed under the brand name Pletal by Otsuka Pharmaceutical Co.. Cilostazol works by inhibiting both primary and secondary aggregation and reducing...
Approved
Investigational
Matched Synonyms: … 3,4-dihydro-6-(4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy)-2(1H)-quinolinone ... 6-(4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy)-3,4-dihydro-2(1H)-quinolinone ... 6-[4-(1-Cyclohexyl-1H-tetrazol-5-yl)-butoxy]-3,4-dihydro-1H-quinolin-2-one …
Matched Iupac: … 6-[4-(1-cyclohexyl-1H-1,2,3,4-tetrazol-5-yl)butoxy]-1,2,3,4-tetrahydroquinolin-2-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Matched Iupac: … 6-[4-(1-cyclohexyl-1H-1,2,3,4-tetrazol-5-yl)butoxy]-1,2,3,4-tetrahydroquinolin-2-one …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring …
Desloratadine
Desloratadine is a second generation, tricyclic antihistamine that which has a selective and peripheral H1-antagonist action. It is the active descarboethoxy metabolite of loratidine (a second generation histamine). Desloratidine has a long-lasting effect and does not cause drowsiness because it does not readily enter the central nervous system.
Approved
Investigational
Matched Synonyms: … 8-Chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine ... 8-chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo(5,6)cyclohepta(1,2-b)pyridine …
Matched Iupac: … 13-chloro-2-(piperidin-4-ylidene)-4-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,12,14-hexaene …
Matched Mixtures name: … AIRCOMB 2,5 MG/4 MG GRANÜL İÇEREN SAŞE, 30 ADET ... AIRCOMB 2,5 MG/4 MG GRANÜL İÇEREN SAŞE, 90 ADET ... DESMONT 2.5 MG/4 MG ÇİĞNEME TABLETİ, 30 ADET …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 13-chloro-2-(piperidin-4-ylidene)-4-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,12,14-hexaene …
Matched Mixtures name: … AIRCOMB 2,5 MG/4 MG GRANÜL İÇEREN SAŞE, 30 ADET ... AIRCOMB 2,5 MG/4 MG GRANÜL İÇEREN SAŞE, 90 ADET ... DESMONT 2.5 MG/4 MG ÇİĞNEME TABLETİ, 30 ADET …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Levobunolol
A nonselective beta-adrenoceptor antagonist used in the treatment of glaucoma.
Approved
Matched Synonyms: … (S)-5-(3-((1,1-dimethylethyl)amino)-2-hydroxypropoxy)-3,4-dihydro-1(2H)-naphthalenone …
Matched Iupac: … 5-[(2S)-3-(tert-butylamino)-2-hydroxypropoxy]-1,2,3,4-tetrahydronaphthalen-1-one …
Matched Iupac: … 5-[(2S)-3-(tert-butylamino)-2-hydroxypropoxy]-1,2,3,4-tetrahydronaphthalen-1-one …
Temoporfin
Temoporfin is a photosensitizing agent used in the treatment of squamous cell carcinoma of the head and neck [FDA Label]. It was first authorized for market by the European Medicines Agency in October 2001. It is currently available under the brand name Foscan.
Approved
Investigational
Matched Synonyms: … 2,3-dihydro-5,10,15,20-tetra(m-hydroxyphenyl)porphyrin …
Matched Iupac: … (23),12,14,16,18(21),19-decaen-2-yl]phenol ... 3-[7,12,17-tris(3-hydroxyphenyl)-21,22,23,24-tetraazapentacyclo[16.2.1.1³,⁶.1⁸,¹¹.1¹³,¹⁶]tetracosa-1,3,5,7,11 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds with 4 or More Rings …
Matched Iupac: … (23),12,14,16,18(21),19-decaen-2-yl]phenol ... 3-[7,12,17-tris(3-hydroxyphenyl)-21,22,23,24-tetraazapentacyclo[16.2.1.1³,⁶.1⁸,¹¹.1¹³,¹⁶]tetracosa-1,3,5,7,11 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds with 4 or More Rings …
Diazepam
A benzodiazepine with anticonvulsant, anxiolytic, sedative, muscle relaxant, and amnesic properties and a long duration of action. Its actions are mediated by enhancement of gamma-aminobutyric acid activity. It is used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and...
Approved
Illicit
Investigational
Vet approved
Matched Synonyms: … 7-chloro-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one ... NRL-1 …
Matched Iupac: … 7-chloro-1-methyl-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … Meval 2 ... STESOLID 2 ... DIAPINE TABLET 2 mg …
Matched Iupac: … 7-chloro-1-methyl-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … Meval 2 ... STESOLID 2 ... DIAPINE TABLET 2 mg …
Clorazepic acid
Clorazepic acid (clorazepate) is a water-soluble benzodiazepine with muscle-relaxant and anticonvulsant actions effective in the treatment of anxiety.[A957,L44788] Following administration, clorazepate is rapidly converted to nordiazepam (N-desmethyldiazepam), its active metabolite, before entering systemic circulation. Similar to other benzodiazepines, the active metabolite of clorazepate enhances the binding of gamma-aminobutyric acid (GABA)...
Approved
Illicit
Matched Synonyms: … 7-chloro-2,3-dihydro-2,2-dihydroxy-5-phenyl-1H-1,4-benzodiazepine-3-carboxylic acid …
Matched Iupac: … 7-chloro-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepine-3-carboxylic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … 7-chloro-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepine-3-carboxylic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Tasimelteon
Tasimelteon is a selective dual melatonin receptor agonist indicated for the treatment of Non-24-Hour Sleep-Wake Disorder (N24HSWD). Occurring commonly in blind individuals without light perception, this condition is often characterized by periods of night-time insomnia and day-time sleepiness. In blind individuals, a lack of light stimulation causes an extension of...
Approved
Investigational
Matched Synonyms: … N-{[(1R,2R)-2-(2,3-dihydro-1-benzofuran-4-yl)cyclopropyl]methyl}propanamide …
Matched Iupac: … N-{[(1R,2R)-2-(2,3-dihydro-1-benzofuran-4-yl)cyclopropyl]methyl}propanamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … N-{[(1R,2R)-2-(2,3-dihydro-1-benzofuran-4-yl)cyclopropyl]methyl}propanamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Nalidixic acid
Nalidixic acid is a synthetic 1,8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum. It is an inhibitor of the A subunit of bacterial DNA gyrase.
Approved
Investigational
Matched Synonyms: … 1-ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid ... 1-ethyl-7-methyl-1,4-dihydro-1,8-naphthyridin-4-one-3-carboxylic acid ... 1-Ethyl-7-methyl-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid …
Matched Iupac: … 1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid …
Matched Categories: … 4-Quinolones ... Heterocyclic Compounds, 2-Ring …
Matched Iupac: … 1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid …
Matched Categories: … 4-Quinolones ... Heterocyclic Compounds, 2-Ring …
Eszopiclone
Eszopiclone, marketed by Sepracor under the brand-name Lunesta, is a nonbenzodiazepine hypnotic drug used to treat insomnia. It is the active stereoisomer of zopiclone, belonging to the class of drugs known as cyclopyrrolones.[A179638,L6850] Cyclopyrrolone drugs demonstrate high efficacy and low toxicity , offering a safer alternative to other drugs used...
Approved
Investigational
Matched Synonyms: … 1-Piperazinecarobxylic acid,4-methyl-,(5S)-6-(5-chloro-2-pyridinyl)-6,7-dihydro-7-oxo-5H-pyrrolo[3,4- ... (S)-6-(5-Chloro-2-pyridinyl)- 7-oxo- 6,7-dihydro- 5H-pyrrolo[3,4-b]pyrazin-5-yl- 4-methyl- 1-piperazinecarboxylate ... (+)-(5S)-6-(5-Chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo(3,4-b)pyrazin-5-yl 4-methylpiperazine- …
Matched Iupac: … (5S)-6-(5-chloropyridin-2-yl)-7-oxo-5H,6H,7H-pyrrolo[3,4-b]pyrazin-5-yl 4-methylpiperazine-1-carboxylate …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … ZOMILAN 1 MG ... Esogno 1 mg-Filmtabletten ... ZOPLIMAX 1 MG TABLETAS CUBIERTAS …
Matched Iupac: … (5S)-6-(5-chloropyridin-2-yl)-7-oxo-5H,6H,7H-pyrrolo[3,4-b]pyrazin-5-yl 4-methylpiperazine-1-carboxylate …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … ZOMILAN 1 MG ... Esogno 1 mg-Filmtabletten ... ZOPLIMAX 1 MG TABLETAS CUBIERTAS …
Enoxacin
A broad-spectrum 6-fluoronaphthyridinone antibacterial agent (fluoroquinolones) structurally related to nalidixic acid.
Approved
Investigational
Matched Synonyms: … 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8-naphthyridine-3-carboxylic acid ... 1-Ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid …
Matched Iupac: … 1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … 1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Doxazosin
Doxazosin is an alpha-1 antagonist used for the treatment of benign prostatic hypertrophy (BPH) symptoms and hypertension. Other members of this drug class include Prazosin, Terazosin, Tamsulosin, and Alfuzosin. Because of its long-lasting effects, doxazosin can be administered once a day. It is marketed by Pfizer and was initially approved...
Approved
Matched International brands: … Cardura-1 ... Cardura-2 ... Cardura-4 …
Matched Synonyms: … 1-(4-Amino-6,7-dimethoxy-2-chinazolinyl)-4-(2,3-dihydro-1,4-benzodioxixin-2-ylcarbonyl)piperazin ... 1-(4-Amino-6,7-Dimethoxy-2-quinazolinyl)-4-(1,4-benzodioxan-2-ylcarbonyl)piperazin …
Matched Iupac: … 2-[4-(2,3-dihydro-1,4-benzodioxine-2-carbonyl)piperazin-1-yl]-6,7-dimethoxyquinazolin-4-amine …
Matched Description: … Doxazosin is an alpha-1 antagonist used for the treatment of benign prostatic hypertrophy (BPH) symptoms …
Matched Mixtures name: … Cardura-1,2,and 4 ... Cardura-1,2,and 4 ... Cardura-1,2,and 4 …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Peripheral alpha-1 blockers ... Adrenergic alpha-1 Receptor Antagonists …
Matched Products: … ซาโดซิน 1 ... Doxazosin-1 ... คาร์ดูรา (1 มก.) …
Matched Synonyms: … 1-(4-Amino-6,7-dimethoxy-2-chinazolinyl)-4-(2,3-dihydro-1,4-benzodioxixin-2-ylcarbonyl)piperazin ... 1-(4-Amino-6,7-Dimethoxy-2-quinazolinyl)-4-(1,4-benzodioxan-2-ylcarbonyl)piperazin …
Matched Iupac: … 2-[4-(2,3-dihydro-1,4-benzodioxine-2-carbonyl)piperazin-1-yl]-6,7-dimethoxyquinazolin-4-amine …
Matched Description: … Doxazosin is an alpha-1 antagonist used for the treatment of benign prostatic hypertrophy (BPH) symptoms …
Matched Mixtures name: … Cardura-1,2,and 4 ... Cardura-1,2,and 4 ... Cardura-1,2,and 4 …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Peripheral alpha-1 blockers ... Adrenergic alpha-1 Receptor Antagonists …
Matched Products: … ซาโดซิน 1 ... Doxazosin-1 ... คาร์ดูรา (1 มก.) …
Eliglustat
Eliglustat is a glucosylceramide synthase inhibitor used for the long-term treatment of type 1 Gaucher disease.[A3752,L41404] Gaucher disease is a rare genetic disorder characterized by the deficiency of acid β-glucosidase, an enzyme that converts glucosylceramide into glucose and ceramide. In patients with Gaucher disease, the accumulation of glucosylceramide leads to...
Approved
Investigational
Matched Synonyms: … N-[(1R,2R)-1-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1-hydroxy-3-(1-pyrrolidinyl)-2-propanyl]octanamide …
Matched Iupac: … N-[(1R,2R)-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-hydroxy-3-(pyrrolidin-1-yl)propan-2-yl]octanamide …
Matched Description: … Eliglustat is a glucosylceramide synthase inhibitor used for the long-term treatment of type 1 Gaucher ... the FDA in August 2014 as an oral substrate reduction therapy for the first-line treatment of type 1 ... [L41404,A7634] Enzyme replacement continues to be the standard of care for the treatment of type 1 Gaucher …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … N-[(1R,2R)-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-hydroxy-3-(pyrrolidin-1-yl)propan-2-yl]octanamide …
Matched Description: … Eliglustat is a glucosylceramide synthase inhibitor used for the long-term treatment of type 1 Gaucher ... the FDA in August 2014 as an oral substrate reduction therapy for the first-line treatment of type 1 ... [L41404,A7634] Enzyme replacement continues to be the standard of care for the treatment of type 1 Gaucher …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Oxcarbazepine
Oxcarbazepine is an anti-epileptic medication used in the treatment of partial onset seizures that was first approved for use in the United States in 2000.[L8627,L8630,L8633] It is a structural derivative of carbamazepine and exerts a majority of its activity via a pharmacologically active metabolite, MHD, which exists as a racemate...
Approved
Matched Synonyms: … 10,11-Dihydro-10-oxo-5H-dibenz(b,f)azepine-5-carboxamide …
Matched Iupac: … 9-oxo-2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,11,13-hexaene-2-carboxamide …
Matched Iupac: … 9-oxo-2-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,11,13-hexaene-2-carboxamide …
Antipyrine
An analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
Approved
Investigational
Matched Synonyms: … 1,2-Dihydro-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one ... 2,3-Dimethyl-1-phenyl-5-pyrazolone …
Matched Iupac: … 1,5-dimethyl-2-phenyl-2,3-dihydro-1H-pyrazol-3-one …
Matched Categories: … Non COX-2 selective NSAIDS ... Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 1,5-dimethyl-2-phenyl-2,3-dihydro-1H-pyrazol-3-one …
Matched Categories: … Non COX-2 selective NSAIDS ... Heterocyclic Compounds, 1-Ring …
Olutasidenib
Olutasidenib (FT-2102) is a selective and potent isocitrate dehydrogenase-1 (IDH1) inhibitor approved by the FDA in December 2022.[L44256,L44261] It is indicated for the treatment of relapsed or refractory acute myeloid leukemia (AML) in patients with a susceptible IDH1 mutation as determined by an FDA-approved test. IDH1 mutations are common in...
Approved
Investigational
Matched Synonyms: … 2-pyridinecarbonitrile, 5-(((1s)-1-(6-chloro-1,2-dihydro-2-oxo-3-quinolinyl)ethyl)amino)-1,6-dihydro- ... (s)-5-((1-(6-chloro-2-oxo-1,2-dihydroquinolin-3-yl)ethyl)amino)-1-methyl-6-oxo-1,6-dihydropyridine-2- ... 5-(((1s)-1-(6-chloro-2-oxo-1,2-dihydroquinolin-3-yl)ethyl)amino)-1-methyl-6-oxo-1,6-dihydropyridine-2 …
Matched Iupac: … 5-{[(1S)-1-(6-chloro-2-oxo-1,2-dihydroquinolin-3-yl)ethyl]amino}-1-methyl-6-oxo-1,6-dihydropyridine-2 …
Matched Description: … Olutasidenib (FT-2102) is a selective and potent isocitrate dehydrogenase-1 (IDH1) inhibitor approved ... hydroxyglutarate (2-HG), a metabolite that participates in tumerogenesis. ... cholangiocarcinoma, chondrosarcoma, and myelodysplastic syndromes (MDS), and they lead to an increase in 2- …
Matched Categories: … MATE 2 Inhibitors ... Heterocyclic Compounds, 2-Ring ... MATE 1 Inhibitors ... Heterocyclic Compounds, 1-Ring ... Isocitrate Dehydrogenase-1 Inhibitors …
Matched Iupac: … 5-{[(1S)-1-(6-chloro-2-oxo-1,2-dihydroquinolin-3-yl)ethyl]amino}-1-methyl-6-oxo-1,6-dihydropyridine-2 …
Matched Description: … Olutasidenib (FT-2102) is a selective and potent isocitrate dehydrogenase-1 (IDH1) inhibitor approved ... hydroxyglutarate (2-HG), a metabolite that participates in tumerogenesis. ... cholangiocarcinoma, chondrosarcoma, and myelodysplastic syndromes (MDS), and they lead to an increase in 2- …
Matched Categories: … MATE 2 Inhibitors ... Heterocyclic Compounds, 2-Ring ... MATE 1 Inhibitors ... Heterocyclic Compounds, 1-Ring ... Isocitrate Dehydrogenase-1 Inhibitors …
Epinastine
Epinastine is used for the prevention of itching associated with allergic conjunctivitis. It has a multi-action effect that inhibits the allergic response in 3 ways: 1. stabilizes mast cells by preventing mast cell degranulation to control the allergic response, 2. prevents histamine binding to both the H1- and H2-receptors to...
Approved
Investigational
Matched Synonyms: … 3-amino-9,13b-dihydro-1H-dibenz(c,f)imidazo(1,5-a)azepine …
Matched Iupac: … 2,4-diazatetracyclo[12.4.0.0^{2,6}.0^{7,12}]octadeca-1(18),3,7,9,11,14,16-heptaen-3-amine …
Matched Description: … It has a multi-action effect that inhibits the allergic response in 3 ways: 1. stabilizes mast cells ... by preventing mast cell degranulation to control the allergic response, 2. prevents histamine binding …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 2,4-diazatetracyclo[12.4.0.0^{2,6}.0^{7,12}]octadeca-1(18),3,7,9,11,14,16-heptaen-3-amine …
Matched Description: … It has a multi-action effect that inhibits the allergic response in 3 ways: 1. stabilizes mast cells ... by preventing mast cell degranulation to control the allergic response, 2. prevents histamine binding …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Moxifloxacin
Moxifloxacin is a synthetic fluoroquinolone antibiotic agent. Bayer AG developed the drug (initially called BAY 12-8039) and it is marketed worldwide (as the hydrochloride) under the brand name Avelox (in some countries also Avalox) for oral treatment.
Approved
Investigational
Matched Synonyms: … 1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-((4as,7as)-octahydro-6H-pyrrolo(3,4-b)pyridin-6-yl)-4- …
Matched Iupac: … 7-[(4aS,7aS)-octahydro-1H-pyrrolo[3,4-b]pyridin-6-yl]-1-cyclopropyl-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline …
Matched Salts cas: … 192927-63-2 …
Matched Mixtures name: … MOXİDEXA % 0,5 + % 0,1 GÖZ DAMLASI, ÇÖZELTİ, 1 ADET …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … COZELTISI ICEREN FLAKON, 1 ADET ... MOXAFLOX 5MG/ML GÖZ DAMLASI , 1 ADET ... MOXİBİEM %0,5 GÖZ DAMLASI, ÇÖZELTİ, 1 ADET …
Matched Iupac: … 7-[(4aS,7aS)-octahydro-1H-pyrrolo[3,4-b]pyridin-6-yl]-1-cyclopropyl-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline …
Matched Salts cas: … 192927-63-2 …
Matched Mixtures name: … MOXİDEXA % 0,5 + % 0,1 GÖZ DAMLASI, ÇÖZELTİ, 1 ADET …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … COZELTISI ICEREN FLAKON, 1 ADET ... MOXAFLOX 5MG/ML GÖZ DAMLASI , 1 ADET ... MOXİBİEM %0,5 GÖZ DAMLASI, ÇÖZELTİ, 1 ADET …
Mercaptopurine
An antimetabolite antineoplastic agent with immunosuppressant properties. It interferes with nucleic acid synthesis by inhibiting purine metabolism and is used, usually in combination with other drugs, in the treatment of or in remission maintenance programs for leukemia.
Approved
Matched Synonyms: … 1,9-DIHYDRO-6H-PURINE-6-THIONE …
Matched Iupac: … 6,7-dihydro-3H-purine-6-thione …
Matched Salts cas: … 6112-76-1 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … 6,7-dihydro-3H-purine-6-thione …
Matched Salts cas: … 6112-76-1 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Indinavir
A potent and specific HIV protease inhibitor that appears to have good oral bioavailability. [PubChem]
Approved
Matched Synonyms: … (1(1S,2R),5(S))-2,3,5-Trideoxy-N-(2,3-dihydro-2-hydroxy-1H-inden-1-yl)-5-(2-(((1,1-dimethylethyl)amino ... )carbonyl)-4-(3-pyridinylmethyl)-1-piperazinyl)-2-(phenylmethyl)-D-erythro-pentonamide …
Matched Iupac: … (2S)-1-[(2S,4R)-4-benzyl-2-hydroxy-4-{[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]carbamoyl}butyl]-N-tert-butyl ... -4-[(pyridin-3-yl)methyl]piperazine-2-carboxamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … (2S)-1-[(2S,4R)-4-benzyl-2-hydroxy-4-{[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]carbamoyl}butyl]-N-tert-butyl ... -4-[(pyridin-3-yl)methyl]piperazine-2-carboxamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Diltiazem
Diltiazem is a benzothiazepine derivative with antihypertensive and vasodilating properties. Approved in 1982 by the FDA, it is a member of the non-dihydropyridine calcium channel blockers drug class. It works through various mechanisms of action, but it primarily works by inhibiting the calcium influx into cardiac and vascular smooth muscle...
Approved
Investigational
Matched Synonyms: … (+)-cis-5-[2-(dimethylamino)ethyl]-2,3-dihydro-3-hydroxy-2-(p-methoxyphenyl)-1,5-benzothiazepin-4(5H) ... (2S-cis)-3-(acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin- ... (2S,3S)-5-(2-(dimethylamino)ethyl)-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin …
Matched Iupac: … (2S,3S)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3- …
Matched Salts cas: … 144604-00-2 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … KAFİZEM %2 KREM , 30 G ... Diltiarec %2 Krem, 30 G ... LOCAFEN % 2 KREM, 30 GRAM …
Matched Iupac: … (2S,3S)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepin-3- …
Matched Salts cas: … 144604-00-2 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … KAFİZEM %2 KREM , 30 G ... Diltiarec %2 Krem, 30 G ... LOCAFEN % 2 KREM, 30 GRAM …
Dasabuvir
Dasabuvir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common...
Approved
Matched Synonyms: … -dihydro-2H-pyrimidin-1-ide hydrate (1:1:1) ... Sodium 3-(3-tert-butyl-4-methoxy-5-{6 [(methylsulfonyl)amino]naphthalene-2-yl}phenyl)-2,6-dioxo-3,6 ... N-{6-[3-tert-butyl-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2-methoxyphenyl]naphthalen-2-yl}methanesulfonamide …
Matched Iupac: … N-{6-[3-tert-butyl-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-2-methoxyphenyl]naphthalen-2-yl}methanesulfonamide …
Matched Description: … HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 ... are poorly conserved across HCV genotypes leading to the restriction of Dasabuvir's use to genotype 1 …
Matched Salts cas: … 1132940-11-4 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … N-{6-[3-tert-butyl-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-2-methoxyphenyl]naphthalen-2-yl}methanesulfonamide …
Matched Description: … HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 ... are poorly conserved across HCV genotypes leading to the restriction of Dasabuvir's use to genotype 1 …
Matched Salts cas: … 1132940-11-4 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Displaying drugs 651 - 675 of 5185 in total