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Displaying drugs 251 - 275 of 332 in total
Fludrocortisone is a synthetic mineralocorticoid used in conjunction with hydrocortisone to replace missing endogenous corticosteroids in patients with adrenal insufficiency.[A187169,A187187] It is functionally similar to aldosterone, the body's primary endogenous mineralocorticoid, and is structurally analogous to cortisol, differing only by a fluorine atom at the 9-position of the steroid structure...
Approved
Investigational
Matched Iupac: … (1R,3aS,3bS,9aS,9bR,10S,11aS)-9b-fluoro-1,10-dihydroxy-1-(2-hydroxyacetyl)-9a,11a-dimethyl-1H,2H,3H,3aH ... ,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one …
Matched Salts cas: … 514-36-3
Matched Categories: … Cytochrome P-450 Substrates ... Cytochrome P-450 CYP3A Substrates ... Cytochrome P-450 CYP3A4 Substrates …
Homatropine methylbromide is a quaternary ammonium muscarinic acetylcholine receptor antagonist belonging to the group of medicines called anti-muscarinics. Homatropine is used to treat duodenal or stomach ulcers or intestine problems. It can be used together with antacids or other medicine in the treatment of peptic ulcer. It may also be...
Approved
Matched Synonyms: … 3-alpha-Hydroxy-8-methyl-1-alpha-H,5-alpha-H-tropanium bromide mandelate …
Matched Iupac: … 3-[(2-hydroxy-2-phenylacetyl)oxy]-8,8-dimethyl-8-azabicyclo[3.2.1]octan-8-ium bromide …
Digoxin is one of the oldest cardiovascular medications used today. It is a common agent used to manage atrial fibrillation and the symptoms of heart failure. Digoxin is classified as a cardiac glycoside and was initially approved by the FDA in 1954. This drug originates from the foxglove plant, also...
Approved
Matched Iupac: … 4-[(1R,3aS,3bR,5aR,7S,9aS,9bS,11R,11aS)-7-{[(2R,4S,5S,6R)-5-{[(2S,4S,5S,6R)-5-{[(2S,4S,5S,6R)-4,5-dihydroxy ... -9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]-2,5-dihydrofuran-2-one ... -6-methyloxan-2-yl]oxy}-4-hydroxy-6-methyloxan-2-yl]oxy}-4-hydroxy-6-methyloxan-2-yl]oxy}-3a,11-dihydroxy …
Matched Categories: … P-glycoprotein inducers ... P-glycoprotein inhibitors ... P-glycoprotein substrates ... P-glycoprotein substrates with a Narrow Therapeutic Index …
Matched Products: … DIGOXIN-ASSOS 0,5 MG /2 ML IV ENJEKSİYON İÇEREN AMPUL, 5 ADET ... LANOXIN INJECTION 0.5 mg/2 ml …
Pinacidil is a cyanoguanidine drug that acts by opening ATP-sensitive potassium channels, leading to peripheral vasodilatation of arterioles and decreasing peripheral vascular resistance. The above processes result in reduced blood pressure. This drug has been discontinued by the FDA.
Approved
Matched Iupac: … (Z)-N'-cyano-N-(3,3-dimethylbutan-2-yl)-N''-(pyridin-4-yl)guanidine …
Matched Description: … Pinacidil is a cyanoguanidine drug that acts by opening ATP-sensitive potassium channels, leading to …
Matched Categories: … Potassium Channel Opener ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP3A Substrates ... Cytochrome P-450 CYP3A4 Substrates …
Glucose is a simple sugar (monosaccharide) generated during phosynthesis involving water, carbon and sunlight in plants. It is produced in humans via hepatic gluconeogenesis and breakdown of polymeric glucose forms (glycogenolysis). It circulates in human circulation as blood glucose and acts as an essential energy source for many organisms through...
Approved
Investigational
Vet approved
Matched Iupac: … (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal …
Matched Salts cas: … 77938-63-7
Matched Mixtures name: … Isolyte S in Dextrose ... Prismasol Bgk2/0 ... Prismasol B22gk4/0
Matched Products: … DEXTROSE INJ 5% BP (1000ML P/C) ... %5 DEKSTROZ SUDAKI ÇÖZELTISI BFS ,150 ML, 1 ŞIŞE, SETLI ... %5 DEKSTROZ SUDAKI ÇÖZELTISI BFS ,250 ML, 1 ŞIŞE, SETLI …
Glycodiazine is used with diet to lower blood glucose by increasing the secretion of insulin from pancreas and increasing the sensitivity of peripheral tissues to insulin. The mechanism of action of glycodiazine in lowering blood glucose appears to be dependent on stimulating the release of insulin from functioning pancreatic beta...
Approved
Investigational
Matched Iupac: … N-[5-(2-methoxyethoxy)pyrimidin-2-yl]benzenesulfonamide …
Matched Description: … It is used for the concomitant use with insulin for the treatment of noninsulin-dependent (type 2) diabetes ... , reducing potassium conductance and causing depolarization of the membrane. ... Glycodiazine likely binds to ATP-sensitive potassium channel receptors on the pancreatic cell surface …
A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p826)
Approved
Matched Iupac: … 6-chloro-2-methyl-1,1-dioxo-3-{[(2,2,2-trifluoroethyl)sulfanyl]methyl}-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine ... -7-sulfonamide …
Matched Mixtures name: … Renese-R
Matched Categories: … polythiazide and potassium ... Heterocyclic Compounds, 2-Ring …
Rabeprazole is an antiulcer drug in the class of proton pump inhibitors. It is a prodrug - in the acid environment of the parietal cells it turns into active sulphenamide form. Rabeprazole inhibits the H+, K+ATPase of the coating gastric cells and dose-dependent oppresses basal and stimulated gastric acid secretion.
Approved
Investigational
Matched Iupac: … 2-{[4-(3-methoxypropoxy)-3-methylpyridin-2-yl]methanesulfinyl}-1H-1,3-benzodiazole …
Matched Description: … It is a prodrug - in the acid environment of the parietal cells it turns into active sulphenamide form ... H+, K+ATPase of the coating gastric cells and dose-dependent oppresses basal and stimulated gastric acid
Matched Salts cas: … 117976-90-6
Matched Categories: … Carboxylic Acids ... Heterocyclic Compounds, 1-Ring ... Acid Reducers ... 2-Pyridinylmethylsulfinylbenzimidazoles ... Heterocyclic Compounds, 2-Ring …
Matched Products: … Raberprazole Sodium D/r
The plasma protein fraction human (PPFh) is defined as a sterile solution of proteins composed mainly of albumin and globulin derived from human plasma. It is already reviewed under the category of biologics by the FDA where the processing, required tests, requirements and labeling are incorporated. This biologic should come...
Approved
Matched Description: … It is also stated that no more than 1% of the total protein should be gamma globulin. ... The composition of PPFh should be 5% of protein from which 83% should consist of albumin and no more ... stabilized with sodium caprylate and acetyltryptophan and it contains some electrolytes such as sodium, potassium
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … SANDOGLOBULINA 6 G ... Octaplas SD Blutgruppe 0 zur Infusion ... PLASMANATE INJECTION 5% …
Rocuronium (rapid onset-curonium) is a desacetoxy analogue of vecuronium with a more rapid onset of action. It is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia, to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation. Introduced in 1994, rocuronium has...
Approved
Matched Iupac: … 1-[(1R,2S,3aS,3bR,5aS,7S,8S,9aS,9bS,11aS)-1-(acetyloxy)-7-hydroxy-9a,11a-dimethyl-8-(morpholin-4-yl)- ... hexadecahydro-1H-cyclopenta[a]phenanthren-2-yl]-1-(prop-2-en-1-yl)pyrrolidin-1-ium …
Matched Products: … ROCUREX(R)100MG ... JECRON 50 MG/5 ML IV ENJEKSİYONLUK ÇÖZELTİ, 1 ADET ... JECRON 50 MG/5 ML IV ENJEKSİYONLUK ÇÖZELTİ, 1 ADET AMPUL …
Cyclopenthiazide is a thiazide diuretic with antihypertensive properties. In a double blind, randomized crossover study, cyclopenthiazide was effective in reducing diastolic blood pressure in mildly hypertensive non-insulin dependent diabetic patients . It is a positive allosteric modulator at AMPA-A receptors .
Approved
Matched Iupac: … 6-chloro-3-(cyclopentylmethyl)-1,1-dioxo-3,4-dihydro-2H-1λ⁶,2,4-benzothiadiazine-7-sulfonamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... cyclopenthiazide and potassium ... cyclopenthiazide and potassium-sparing agents ... Low-Ceiling Diuretics and Potassium-Sparing Agents …
Prednisolone acetate is a prednisolone molecule bound to an acetate functional group by an ester bond. Prednisolone acetate was granted FDA approval in 1955.
Approved
Vet approved
Matched Iupac: … 2-[(1R,3aS,3bS,9aR,9bS,10S,11aS)-1,10-dihydroxy-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH ... ,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-oxoethyl acetate …
Matched Mixtures name: … CONJUNTIN-S® LIQUIFILM® SUSPENSION OFTALMICA ESTERIL ... SUPRENIL STERIL OFTALMIK SUSPANSIYON 5 ML ... BLEPHAMIDE % 0,2 + % 10 GÖZ DAMLASI, SÜSPANSİYON, 5 ML …
Matched Categories: … P-glycoprotein substrates ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP3A Inducers ... Cytochrome P-450 CYP3A4 Inducers ... Cytochrome P-450 CYP3A Substrates …
Matched Products: … PRED FORTE % 1 GÖZ DAMLASI, SÜSPANSİYON, 5 ML ... Ak Tate Oph Sus 1% ... Diopred Suspension 1% …
Prednisolone phosphate is a glucocorticoid similar to cortisol used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects. Prednisolone phosphate was granted FDA Approval on 19 December 1973.
Approved
Vet approved
Matched Iupac: … {2-[(1R,3aS,3bS,9aR,9bS,10S,11aS)-1,10-dihydroxy-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH, ... 9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-oxoethoxy}phosphonic acid
Matched Salts cas: … 125-02-0
Matched Categories: … P-glycoprotein inducers ... Cytochrome P-450 CYP2A6 Inducers ... P-glycoprotein substrates ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2B6 Inducers …
Matched Products: … METICORTELONE® SOLUCION ORAL 3 MG /ML ... XILONE Syrup 5 mg / 5 ml ... PREDNISOLONE SYRUP 5 mg/5 ml …
Ethinylestradiol was first synthesized in 1938 by Hans Herloff Inhoffen and Walter Hohlweg at Schering. It was developed in an effort to create an estrogen with greater oral bioavailability. These properties were achieved by the substitution of an ethinyl group at carbon 17 of estradiol. Ethinylestradiol soon replaced mestranol in...
Approved
Matched Iupac: … (1R,3aS,3bR,9bS,11aS)-1-ethynyl-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta[a]phenanthrene …
Matched Mixtures name: … Drosfemine 0,02 mg/3 mg 24+4 Filmtabletten ... YAZZ 3 MG/0.02 MG FILM KAPLI TABLET, 3×(24+4) TABLET, 28 ADET ... DROSPERA 3 MG/0.02 MG FILM KAPLI TABLET,24+4 ADET …
Matched Categories: … P-glycoprotein substrates ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP1A2 Substrates ... Cytochrome P-450 CYP3A Substrates ... Cytochrome P-450 CYP2C8 Inhibitors …
Magnesium oxide is an inorganic compound that occurs in nature as the mineral periclase. In aqueous media combines quickly with water to form magnesium hydroxide. It is used as an antacid and mild laxative and has many nonmedicinal uses.
Approved
Matched Iupac: … magnesium(2+) oxidandiide …
Matched Mixtures name: … Calcium Magnesium 2:1 Tablets With Vitamin D ... B 6 Plus ... Pregvit Folic 4
Matched Categories: … Gastric Acid Lowering Agents ... Drugs for Acid Related Disorders …
Lubiprostone is a medication used in the management of idiopathic chronic constipation. A prostaglandin E1 derivative, lubiprostone is a bicyclic fatty acid that activates ClC-2 chloride channels located on the apical side of the gastrointestinal epithelial cells. Activation of these channels promotes the secretion of a chloride-rich fluid that soften...
Approved
Investigational
Matched Iupac: … 7-[(2R,4aR,5R,7aR)-2-(1,1-difluoropentyl)-2-hydroxy-6-oxo-octahydrocyclopenta[b]pyran-5-yl]heptanoic ... acid
Matched Description: … A prostaglandin E1 derivative, lubiprostone is a bicyclic fatty acid that activates ClC-2 chloride channels …
Oxyphencyclimine is an anticholinergic drug (trade name Daricon) used in treating peptic ulcers.
Approved
Matched Iupac: … (1-methyl-1,4,5,6-tetrahydropyrimidin-2-yl)methyl 2-cyclohexyl-2-hydroxy-2-phenylacetate …
Matched Salts cas: … 125-52-0
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Synthetic Anticholinergics, Esters With Tertiary Amino Group …
Matched Products: … ออกซี่เฟน 5 ... ยาเม็ด อ๊อกซีเฟนไซคลีมีน (5 มก.) …
Cyanocobalamin (commonly known as Vitamin B12) is a highly complex, essential vitamin, owing its name to the fact that it contains the mineral, cobalt. This vitamin is produced naturally by bacteria , and is necessary for DNA synthesis and cellular energy production. Vitamin B12 has many forms, including the cyano-,...
Approved
Nutraceutical
Matched International brands: … Neuroforte-R
Matched Iupac: … )-4-(2-{[(2R)-2-{[(2R,3S,4R,5S)-5-(5,6-dimethyl-1H-1,3-benzodiazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan ... [15.2.1.1^{2,5}.1^{7,10}.1^{12,15}]tricosa-5(23),6,10(22),11,15(21),16-hexaen-20-yl]cobaltylium ... -3-yl phosphonato]oxy}propyl]carbamoyl}ethyl)-1,4,6,9,9,14,16,19-octamethyl-20,21,22,23-tetraazapentacyclo ... cyano[(1R,2R,3R,4R,6Z,8S,11Z,13S,14S,16Z,18S,19S)-8,13,18-tris(2-carbamoylethyl)-3,14,19-tris(carbamoylmethyl …
Matched Mixtures name: … RUBIRON+6 AMPUL, 5 ADET ... ENJEKSİYONLUK ÇÖZELTİ İÇEREN AMPUL (1 ML VE 2 ML) X 6 AMPUL ... P-NATAL® …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds with 4 or More Rings ... Vitamin B12 and Folic Acid ... iron, vitamin B12 and folic acid
Matched Products: … MONOVİT B12 1000 mcg/1 ml IM Enjeksiyonluk Cözelti, 5 ADET ... VİTAKOBAL 1000 MCG/1 ML İ.M. ENJEKSİYONLUK ÇÖZELTİ, 5 ADET ... VITAMINA B12 1 MG/ML INYECTABLE …
Isosorbide mononitrate is an organic nitrate with vasodilating properties. It is an anti-anginal agent that works by relaxing the smooth muscles of both arteries and veins, but but predominantly veins to reduce cardiac preload.[L11698, L11743] Isosorbide mononitrate is an active metabolite of isosorbide dinitrate. Like other organic nitrates, isosorbide mononitrate...
Approved
Matched Synonyms: … IS 5-MN ... IS-5-MN ... Iso-5-mononitrate …
Matched Iupac: … (3R,3aS,6S,6aR)-6-hydroxy-hexahydrofuro[3,2-b]furan-3-yl nitrate …
Matched Products: … IS 5 MONO RATIO 20MG TAB ... IS 5 MONO RATIO 40MG RET ... IS 5 MONO RATIO 40MG TAB …
Moexipril is a non-sulfhydryl containing precursor of the active angiotensin-converting enzyme (ACE) inhibitor moexiprilat. It is used to treat high blood pressure (hypertension). It works by relaxing blood vessels, causing them to widen. Lowering high blood pressure helps prevent strokes, heart attacks and kidney problems.
Approved
Matched Iupac: … (3S)-2-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline ... -3-carboxylic acid
Matched Salts cas: … 82586-52-5
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Finerenone, or BAY 94-8862, is a mineralocorticoid receptor antagonist indicated to reduce the risk of sustained decline in glomerular filtration rate, end stage kidney disease, cardiovascular death, heart attacks, and hospitalization due to heart failure in adults with chronic kidney disease associated with type II diabetes mellitus.[A236519,L34739] Patients with kidney...
Approved
Investigational
Matched Iupac: … (4S)-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2C8 Substrates ... Cytochrome P-450 CYP3A Substrates ... Cytochrome P-450 CYP3A4 Substrates …
Experimental
Matched Synonyms: … Dipotassium monophosphate trihydrate ... Dipotassium hydrogen phosphate trihydrate
Matched Name: … Potassium phosphate, dibasic, trihydrate
Matched Iupac: … dipotassium trihydrate hydrogen phosphate …
Potassium bitartate, also referred to as potassium acid tartrate or cream of tartar, is the potassium acid salt of l-( + )-tartaric acid. It is obtained as a byproduct of wine manufacture during the fermentation process. Approved by the FDA as a direct food substance, potassium bitartrate is used as...
Experimental
Matched Synonyms: … Potassium bitartrate ... potassium hydrogen tartrate …
Matched Name: … Potassium bitartrate …
Matched Iupac: … potassium (2R,3R)-3-carboxy-2,3-dihydroxypropanoate …
Matched Description: … Potassium bitartate, also referred to as potassium acid tartrate or cream of tartar, is the potassium ... acid salt of l-( + )-tartaric acid. ... Approved by the FDA as a direct food substance, potassium bitartrate is used as an additive, stabilizer …
Matched Categories: … Potassium Salt …
Guaiacolsulfonate is an aromatic sulfonic acid. Potassium guaiacolsulfonate salt is an expectorant that thins the mucus in the lungs and reduces chest congestion.
Experimental
Matched Synonyms: … Guaiacolsulfonate potassium ... Potassium sulfoguaiacolate …
Matched Name: … Potassium guaiacolsulfonate …
Matched Description: … Guaiacolsulfonate is an aromatic sulfonic acid. ... Potassium guaiacolsulfonate salt is an expectorant that thins the mucus in the lungs and reduces chest …
Matched Mixtures name: … P-Tuss ... Phenylephrine Carbetapentane Potassium Guaiacolsulfonate …
Matched Categories: … Potassium Salt …
Experimental
Investigational
Matched Synonyms: … Potassium permanganate …
Matched Name: … Potassium permanganate …
Matched Iupac: … potassium manganesoylolate …
Matched Categories: … Potassium Salt ... Potassium Compounds ... potassium permanganate ... potassium permanganate …
Displaying drugs 251 - 275 of 332 in total