Displaying drugs 301 - 325 of 15140 in total
Ozenoxacin
To date, ozenoxacin has been used in trials studying the treatment of impetigo.
As of December 11, 2017 the FDA approved Ferrer Internacional S.A.'s Xepi (ozenoxacin 1%) as a topically applied cream indicated for the treatment of impetigo caused by Staphylococccus aureus or Streptococcus pyogenes in adult and pediatric patients...
Approved
Investigational
Matched Iupac: … 1-cyclopropyl-8-methyl-7-[5-methyl-6-(methylamino)pyridin-3-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic …
Matched Description: … has demonstrated safe and effective therapy in both the adult and pediatric population. ... pediatric patients 2 months of age and older. ... Despite being a common and highly contagious bacerial skin infection that affects millions of children …
Matched Description: … has demonstrated safe and effective therapy in both the adult and pediatric population. ... pediatric patients 2 months of age and older. ... Despite being a common and highly contagious bacerial skin infection that affects millions of children …
Propranolol
Propranolol is a racemic mixture of 2 enantiomers where the S(-)-enantiomer has approximately 100 times the binding affinity for beta adrenergic receptors. Propranolol is used to treat a number of conditions but most commonly is used for hypertension.[L6901,L6904,L6907]
Propranolol was granted FDA approval on 13 November 1967.
Approved
Investigational
Matched Mixtures name: … Propranolol Hydrochloride and Hydrochlorothiazide ... Propranolol Hydrochloride and Hydrochlorothiazide ... Propranolol Hydrochloride and Hydrochlorothiazide …
Matched Categories: … propranolol and thiazides ... Beta Blocking Agents and Thiazides ... propranolol and other combinations ... Beta Blocking Agents, Non-Selective, and Thiazides …
Matched Categories: … propranolol and thiazides ... Beta Blocking Agents and Thiazides ... propranolol and other combinations ... Beta Blocking Agents, Non-Selective, and Thiazides …
Tiludronic acid
Tiludronate, or (4-chlorophenyl)thio-methylene-1,1-bisphosphonate, is a first generation bisphosphonate similar to etidronic acid and clodronic acid.[A1923,A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and decalcification. Tiludronic acid was first described in the literature in 1988 as a potential treatment for Paget's disease of bone....
Approved
Investigational
Vet approved
Matched Iupac: … {[(4-chlorophenyl)sulfanyl](phosphono)methyl}phosphonic acid …
Matched Description: … thio-methylene-1,1-bisphosphonate, is a first generation bisphosphonate similar to [etidronic acid] and ... A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and …
Matched Categories: … Drugs Affecting Bone Structure and Mineralization …
Matched Description: … thio-methylene-1,1-bisphosphonate, is a first generation bisphosphonate similar to [etidronic acid] and ... A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and …
Matched Categories: … Drugs Affecting Bone Structure and Mineralization …
Technetium Tc-99m oxidronate
Technetium Tc-99m oxidronate, also known as 99mTc-methylene diphosphonate, is a radiopharmaceutical agent. A radiopharmaceutical is defined as a medicinal formulation containing radioisotopes that are used in major clinical areas for diagnosis and/or therapy. The radiopharmaceuticals based on technetium-99m are widely used for diagnostic purposes because 99mTc has a versatile chemistry...
Approved
Matched Iupac: … [hydroxy(phosphono)methyl]phosphonic acid (⁹⁹Tc)technetium …
Matched Description: … [L1140] It was developed by Mallinkrodt nuclear and FDA approved on February 18, 1981. ... medicinal formulation containing radioisotopes that are used in major clinical areas for diagnosis and …
Matched Description: … [L1140] It was developed by Mallinkrodt nuclear and FDA approved on February 18, 1981. ... medicinal formulation containing radioisotopes that are used in major clinical areas for diagnosis and …
Mizolastine
Mizolastine is under investigation in clinical trial NCT01928316 (A Bioequivalence Study of Domestic (Made in China) and Imported Mizolastine Tablets in Healthy Volunteers).
Approved
Investigational
Matched Iupac: … 2-[(1-{1-[(4-fluorophenyl)methyl]-1H-1,3-benzodiazol-2-yl}piperidin-4-yl)(methyl)amino]-3,4-dihydropyrimidin …
Matched Description: … under investigation in clinical trial NCT01928316 (A Bioequivalence Study of Domestic (Made in China) and …
Matched Description: … under investigation in clinical trial NCT01928316 (A Bioequivalence Study of Domestic (Made in China) and …
Dabigatran
Dabigatran is the active form of the orally bioavailable prodrug dabigatran etexilate.
Approved
Investigational
Matched Iupac: … 3-[1-(2-{[(4-carbamimidoylphenyl)amino]methyl}-1-methyl-1H-1,3-benzodiazol-5-yl)-N-(pyridin-2-yl)formamido …
Reboxetine
Reboxetine is an antidepressant drug used in the treatment of clinical depression, panic disorder and ADD/ADHD. Its mesylate (i.e. methanesulfonate) salt is sold under tradenames including Edronax, Norebox, Prolift, Solvex, Davedax or Vestra. Reboxetine has two chiral centers, but it only exists as two enantiomers, (R,R)-(-)- and (S,S)-(+)-reboxetine.
Approved
Experimental
Matched Iupac: … (2R)-2-[(R)-(2-ethoxyphenoxy)(phenyl)methyl]morpholine …
Matched Description: … Reboxetine is an antidepressant drug used in the treatment of clinical depression, panic disorder and ... Reboxetine has two chiral centers, but it only exists as two enantiomers, (R,R)-(-)- and (S,S)-(+)-reboxetine …
Matched Description: … Reboxetine is an antidepressant drug used in the treatment of clinical depression, panic disorder and ... Reboxetine has two chiral centers, but it only exists as two enantiomers, (R,R)-(-)- and (S,S)-(+)-reboxetine …
Mephenytoin
Mephenytoin is used for the treatment of refractory partial epilepsy. Mephenytoin is a solid. This compound belongs to the phenylhydantoins. These are heterocyclic aromatic compounds containing an imiazolidinedione moiety substituted by a phenyl group. Mephenytoin is known to target sodium channel protein type 5 subunit alpha. Cytochrome P450 2C19, Cytochrome...
Approved
Investigational
Withdrawn
Matched Iupac: … 5-ethyl-3-methyl-5-phenylimidazolidine-2,4-dione …
Matched Description: … Mephenytoin and oxazolidinedione derivatives are associated with higher incidences of blood dyscrasias ... Cytochrome P450 2C19, Cytochrome P450 2C8, Cytochrome P450 2C9, Cytochrome P450 2B6, Cytochrome P450 1A2, and …
Matched Description: … Mephenytoin and oxazolidinedione derivatives are associated with higher incidences of blood dyscrasias ... Cytochrome P450 2C19, Cytochrome P450 2C8, Cytochrome P450 2C9, Cytochrome P450 2B6, Cytochrome P450 1A2, and …
Metaxalone
Metaxalone is a moderate to strong muscle relaxant used in the symptomatic treatment of musculoskeletal pain caused by strains, sprains, and other musculoskeletal conditions. It is marketed by King Pharmaceuticals under the brand name Skelaxin®. Its main mechanism of action is thought to involve general central nervous system depression. Metaxalone...
Approved
Matched Iupac: … 5-[(3,5-dimethylphenoxy)methyl]-1,3-oxazolidin-2-one …
Matched Description: … Metaxalone is associated with few side effects and is available as a 800 mg scored tablet. ... muscle relaxant used in the symptomatic treatment of musculoskeletal pain caused by strains, sprains, and …
Matched Description: … Metaxalone is associated with few side effects and is available as a 800 mg scored tablet. ... muscle relaxant used in the symptomatic treatment of musculoskeletal pain caused by strains, sprains, and …
Methdilazine
Methdilazine is a phenothiazine compound with antihistaminic activity. It is used in the treatment of various dermatoses to relieve pruritus.
Approved
Matched Iupac: … 10-[(1-methylpyrrolidin-3-yl)methyl]-10H-phenothiazine …
Pentaerythritol tetranitrate
Pentaerythritol tetranitrate is the nitrate ester of pentaerythritol that possesses explosive properties. When mixed with a plasticizer, this chemical forms a plastic explosive. It is recognized by the FDA to be a coronary vasodilator in the treatment of heart conditions such as angina .
It is a pentaerythritol nitrate in...
Approved
Matched Iupac: … 3-(nitrooxy)-2,2-bis[(nitrooxy)methyl]propyl nitrate …
Matched Description: … that is stored and shipped as a mixture with water and alcohol [L2394]. ... It is also one of the most powerful high explosives known and is a component of the plastic explosive ... It is formed by reacting pentaerythritol (C5H12O4), an alcohol commonly used in paints and varnishes, …
Matched Description: … that is stored and shipped as a mixture with water and alcohol [L2394]. ... It is also one of the most powerful high explosives known and is a component of the plastic explosive ... It is formed by reacting pentaerythritol (C5H12O4), an alcohol commonly used in paints and varnishes, …
Iopanoic acid
Iopanoic acid contains iodine and is useful as a contrast medium in cholecystography.
Approved
Withdrawn
Matched Iupac: … 2-[(3-amino-2,4,6-triiodophenyl)methyl]butanoic acid …
Matched Description: … Iopanoic acid contains iodine and is useful as a contrast medium in cholecystography. …
Matched Description: … Iopanoic acid contains iodine and is useful as a contrast medium in cholecystography. …
Ponatinib
Ponatinib is a novel Bcr-Abl tyrosine kinase inhibitor that is especially effective against the T315I mutation for the treatment of chronic myeloid leukemia. FDA approved on December 14, 2012.
Approved
Investigational
Matched Iupac: … 3-(2-{imidazo[1,2-b]pyridazin-3-yl}ethynyl)-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Dolutegravir
Dolutegravir is an HIV-1 integrase inhibitor that blocks the strand transfer step of the integration of the viral genome into the host cell (INSTI). The effect of this drug has no homology in human host cells, which gives it excellent tolerability and minimal toxicity. Dolutegravir was developed by ViiV Healthcare...
Approved
Matched Iupac: … (3S,7R)-N-[(2,4-difluorophenyl)methyl]-11-hydroxy-7-methyl-9,12-dioxo-4-oxa-1,8-diazatricyclo[8.4.0.0 …
Matched Description: … [A31342] Dolutegravir was developed by ViiV Healthcare and FDA-approved on August 12, 2013. ... The effect of this drug has no homology in human host cells, which gives it excellent tolerability and …
Matched Categories: … lamivudine and dolutegravir ... dolutegravir and rilpivirine ... lamivudine, abacavir and dolutegravir ... lamivudine, tenofovir disoproxil and dolutegravir …
Matched Description: … [A31342] Dolutegravir was developed by ViiV Healthcare and FDA-approved on August 12, 2013. ... The effect of this drug has no homology in human host cells, which gives it excellent tolerability and …
Matched Categories: … lamivudine and dolutegravir ... dolutegravir and rilpivirine ... lamivudine, abacavir and dolutegravir ... lamivudine, tenofovir disoproxil and dolutegravir …
Estradiol
Estradiol is a naturally occurring hormone circulating endogenously in females. It is commercially available in several hormone therapy products for managing conditions associated with reduced estrogen, such as vulvovaginal atrophy and hot flashes. Some available forms of estradiol include oral tablets, injections, vaginal rings, transdermal patches, sprays, gels, and creams.[L11485,L11488,L11491,...
Approved
Investigational
Vet approved
Matched Iupac: … (1S,3aS,3bR,9bS,11aS)-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta[a]phenanthrene-1,7 …
Matched Description: … therapy products for managing conditions associated with reduced estrogen, such as vulvovaginal atrophy and ... forms of estradiol include oral tablets, injections, vaginal rings, transdermal patches, sprays, gels, and ... Ethinyl estradiol is different from estradiol due to its higher biovailability and increased resistance …
Matched Mixtures name: … Estradiol and Progesterone ... Estradiol and Norethindrone Acetate ... Estradiol and Norethindrone Acetate …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Androgens and Estrogens ... Antiandrogens and Estrogens ... etynodiol and estrogen ... dienogest and estrogen …
Matched Description: … therapy products for managing conditions associated with reduced estrogen, such as vulvovaginal atrophy and ... forms of estradiol include oral tablets, injections, vaginal rings, transdermal patches, sprays, gels, and ... Ethinyl estradiol is different from estradiol due to its higher biovailability and increased resistance …
Matched Mixtures name: … Estradiol and Progesterone ... Estradiol and Norethindrone Acetate ... Estradiol and Norethindrone Acetate …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Androgens and Estrogens ... Antiandrogens and Estrogens ... etynodiol and estrogen ... dienogest and estrogen …
Methantheline
Methantheline is a synthetic antispasmodic. Antispasmodics are used to relieve cramps or spasms of the stomach, intestines, and bladder. Methantheline is used to treat intestine or stomach ulcers (peptic ulcer disease), intestine problems (irritable bowel syndrome), pancreatitis, gastritis, biliary dyskinesia, pylorosplasm, or urinary problems (reflex neurogenic bladder in children).
Approved
Investigational
Matched Iupac: … diethyl(methyl)[2-(9H-xanthene-9-carbonyloxy)ethyl]azanium …
Matched Description: … Antispasmodics are used to relieve cramps or spasms of the stomach, intestines, and bladder. …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Description: … Antispasmodics are used to relieve cramps or spasms of the stomach, intestines, and bladder. …
Matched Categories: … Alimentary Tract and Metabolism …
Lapyrium
Lapyrium is a quaternary ammonium cation used as a surfactant, antistatic agent, and biocide in various cosmetic products . It is commonly found formulated as lapyrium chloride.
Approved
Matched Iupac: … 1-({[2-(dodecanoyloxy)ethyl]carbamoyl}methyl)pyridin-1-ium …
Matched Description: … Lapyrium is a quaternary ammonium cation used as a surfactant, antistatic agent, and biocide in various …
Matched Description: … Lapyrium is a quaternary ammonium cation used as a surfactant, antistatic agent, and biocide in various …
Meradimate
Meradimate, before known as menthyl anthranilate, is used in a maximal concentration of 5% in different products as a UV filter. It is currently required to be named as meradimate in all FDA approved OTC products. Meradimate is approved by the FDA and Health Canada to be used as an...
Approved
Matched Iupac: … 5-methyl-2-(propan-2-yl)cyclohexyl 2-aminobenzoate …
Matched Description: … Meradimate is approved by the FDA and Health Canada to be used as an ingredient in sunblocking products …
Matched Mixtures name: … Principal Secret Reclaim Sunscreen For Face and Body SPF 30 …
Matched Description: … Meradimate is approved by the FDA and Health Canada to be used as an ingredient in sunblocking products …
Matched Mixtures name: … Principal Secret Reclaim Sunscreen For Face and Body SPF 30 …
Guanoxan
Guanoxan is an antihypertensive agent similar in its mechanism of action to guanethidine; may cause liver damage.
Guanoxan was approved in the UK but was withdrawn from the market due to hepatotoxicity.
Approved
Matched Iupac: … N-[(2,3-dihydro-1,4-benzodioxin-2-yl)methyl]guanidine …
Naphazoline
Naphazoline is a rapid acting imidazoline sympathomimetic vasoconstrictor of ocular or nasal artierioles[L5804,L5807]. It acts to decrease congestion and is found in many over the counter (OTC) eye drops and nasal preparations[L5804,L5807].
Naphazoline was first developed in 1942 as a nasal formulation for congestion .
Approved
Investigational
Matched Iupac: … 2-[(naphthalen-1-yl)methyl]-4,5-dihydro-1H-imidazole …
Matched Description: … It acts to decrease congestion and is found in many over the counter (OTC) eye drops and nasal preparations …
Matched Mixtures name: … Lubricant and Redness Reliever ... Eye Drops Redness and Dry Eye Relief ... Eye Drops Redness and Dry Eye Relief …
Matched Categories: … Decongestants and Antiallergics …
Matched Description: … It acts to decrease congestion and is found in many over the counter (OTC) eye drops and nasal preparations …
Matched Mixtures name: … Lubricant and Redness Reliever ... Eye Drops Redness and Dry Eye Relief ... Eye Drops Redness and Dry Eye Relief …
Matched Categories: … Decongestants and Antiallergics …
Metyrapone
An inhibitor of the enzyme steroid 11-beta-monooxygenase. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of cushing syndrome.
Approved
Investigational
Matched Iupac: … 2-methyl-1,2-bis(pyridin-3-yl)propan-1-one …
Flecainide
Flecainide is a Class I anti-arrhythmic agent like encainide and propafenone. Flecainide’s development began in 1966 and was first synthesized in 1972 as an attempt to generate new anesthetics. It is used to prevent supraventricular and ventricular arrhythmias, as well as paroxysmal atrial fibrillation and flutter.[L8878,L5056]
Flecainide was granted FDA...
Approved
Withdrawn
Matched Iupac: … N-[(piperidin-2-yl)methyl]-2,5-bis(2,2,2-trifluoroethoxy)benzamide …
Matched Description: … fibrillation and flutter. ... Flecainide is a Class I anti-arrhythmic agent like [encainide] and [propafenone]. ... [A186880] Flecainide’s development began in 1966 and was first synthesized in 1972 as an attempt to generate …
Matched Description: … fibrillation and flutter. ... Flecainide is a Class I anti-arrhythmic agent like [encainide] and [propafenone]. ... [A186880] Flecainide’s development began in 1966 and was first synthesized in 1972 as an attempt to generate …
Isopropamide
Isopropamide iodide is a long-acting quaternary anticholinergic drug. It is used in the treatment of peptic ulcer and other gastrointestinal disorders marked by hyperacidity and hypermotility.
Approved
Vet approved
Matched Iupac: … (3-carbamoyl-3,3-diphenylpropyl)(methyl)bis(propan-2-yl)azanium …
Matched Description: … and hypermotility. ... It is used in the treatment of peptic ulcer and other gastrointestinal disorders marked by hyperacidity …
Matched Categories: … Alimentary Tract and Metabolism ... isopropamide and psycholeptics …
Matched Description: … and hypermotility. ... It is used in the treatment of peptic ulcer and other gastrointestinal disorders marked by hyperacidity …
Matched Categories: … Alimentary Tract and Metabolism ... isopropamide and psycholeptics …
Hexetidine
A bactericidal and fungicidal antiseptic. It is used as a 0.1% mouthwash for local infections and oral hygiene.
Approved
Investigational
Matched Iupac: … 1,3-bis(2-ethylhexyl)-5-methyl-1,3-diazinan-5-amine …
Matched Description: … A bactericidal and fungicidal antiseptic. ... It is used as a 0.1% mouthwash for local infections and oral hygiene. …
Matched Categories: … Alimentary Tract and Metabolism ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... Antiinfectives and Antiseptics for Local Oral Treatment …
Matched Description: … A bactericidal and fungicidal antiseptic. ... It is used as a 0.1% mouthwash for local infections and oral hygiene. …
Matched Categories: … Alimentary Tract and Metabolism ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... Antiinfectives and Antiseptics for Local Oral Treatment …
Sultopride
Sultopride is used in Japan, Hong Kong, and Europe to treat schizophrenia. It is of the drug class atypical antipsychotics .
Approved
Matched Iupac: … 5-(ethanesulfonyl)-N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxybenzamide …
Matched Description: … Sultopride is used in Japan, Hong Kong, and Europe to treat schizophrenia. …
Matched Categories: … Benzamides and benzamide derivatives …
Matched Description: … Sultopride is used in Japan, Hong Kong, and Europe to treat schizophrenia. …
Matched Categories: … Benzamides and benzamide derivatives …
Displaying drugs 301 - 325 of 15140 in total