Displaying drugs 176 - 200 of 332 in total
Rabeprazole
Rabeprazole is an antiulcer drug in the class of proton pump inhibitors. It is a prodrug - in the acid environment of the parietal cells it turns into active sulphenamide form. Rabeprazole inhibits the H+, K+ATPase of the coating gastric cells and dose-dependent oppresses basal and stimulated gastric acid secretion.
Approved
Investigational
Matched Iupac: … 2-{[4-(3-methoxypropoxy)-3-methylpyridin-2-yl]methanesulfinyl}-1H-1,3-benzodiazole …
Matched Description: … It is a prodrug - in the acid environment of the parietal cells it turns into active sulphenamide form ... H+, K+ATPase of the coating gastric cells and dose-dependent oppresses basal and stimulated gastric acid …
Matched Salts cas: … 117976-90-6 …
Matched Categories: … Carboxylic Acids ... Heterocyclic Compounds, 1-Ring ... Acid Reducers ... 2-Pyridinylmethylsulfinylbenzimidazoles ... Heterocyclic Compounds, 2-Ring …
Matched Products: … Raberprazole Sodium D/r …
Matched Description: … It is a prodrug - in the acid environment of the parietal cells it turns into active sulphenamide form ... H+, K+ATPase of the coating gastric cells and dose-dependent oppresses basal and stimulated gastric acid …
Matched Salts cas: … 117976-90-6 …
Matched Categories: … Carboxylic Acids ... Heterocyclic Compounds, 1-Ring ... Acid Reducers ... 2-Pyridinylmethylsulfinylbenzimidazoles ... Heterocyclic Compounds, 2-Ring …
Matched Products: … Raberprazole Sodium D/r …
Polythiazide
A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p826)
Approved
Matched Iupac: … 6-chloro-2-methyl-1,1-dioxo-3-{[(2,2,2-trifluoroethyl)sulfanyl]methyl}-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine ... -7-sulfonamide …
Matched Mixtures name: … Renese-R …
Matched Categories: … polythiazide and potassium ... Heterocyclic Compounds, 2-Ring …
Matched Mixtures name: … Renese-R …
Matched Categories: … polythiazide and potassium ... Heterocyclic Compounds, 2-Ring …
Plasma protein fraction (human)
The plasma protein fraction human (PPFh) is defined as a sterile solution of proteins composed mainly of albumin and globulin derived from human plasma. It is already reviewed under the category of biologics by the FDA where the processing, required tests, requirements and labeling are incorporated. This biologic should come...
Approved
Matched Description: … It is also stated that no more than 1% of the total protein should be gamma globulin. ... The composition of PPFh should be 5% of protein from which 83% should consist of albumin and no more ... stabilized with sodium caprylate and acetyltryptophan and it contains some electrolytes such as sodium, potassium …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … SANDOGLOBULINA 6 G ... Octaplas SD Blutgruppe 0 zur Infusion ... PLASMANATE INJECTION 5% …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … SANDOGLOBULINA 6 G ... Octaplas SD Blutgruppe 0 zur Infusion ... PLASMANATE INJECTION 5% …
Rocuronium
Rocuronium (rapid onset-curonium) is a desacetoxy analogue of vecuronium with a more rapid onset of action. It is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia, to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation. Introduced in 1994, rocuronium has...
Approved
Matched Iupac: … 1-[(1R,2S,3aS,3bR,5aS,7S,8S,9aS,9bS,11aS)-1-(acetyloxy)-7-hydroxy-9a,11a-dimethyl-8-(morpholin-4-yl)- ... hexadecahydro-1H-cyclopenta[a]phenanthren-2-yl]-1-(prop-2-en-1-yl)pyrrolidin-1-ium …
Matched Products: … ROCUREX(R)100MG ... JECRON 50 MG/5 ML IV ENJEKSİYONLUK ÇÖZELTİ, 1 ADET ... JECRON 50 MG/5 ML IV ENJEKSİYONLUK ÇÖZELTİ, 1 ADET AMPUL …
Matched Products: … ROCUREX(R)100MG ... JECRON 50 MG/5 ML IV ENJEKSİYONLUK ÇÖZELTİ, 1 ADET ... JECRON 50 MG/5 ML IV ENJEKSİYONLUK ÇÖZELTİ, 1 ADET AMPUL …
Captopril
Captopril is a potent, competitive inhibitor of angiotensin-converting enzyme (ACE), the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS). Captopril may be used in the treatment of hypertension.
Approved
Matched Synonyms: … (2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid ... D-2-methyl-3-mercaptopropanoyl-L-proline ... D-3-mercapto-2-methylpropanoyl-L-proline …
Matched Iupac: … (2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid …
Matched Categories: … P-glycoprotein inhibitors ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Peptides, and Proteins …
Matched Iupac: … (2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid …
Matched Categories: … P-glycoprotein inhibitors ... Amino Acids ... Amino Acids, Cyclic ... Amino Acids, Peptides, and Proteins …
Cyclopenthiazide
Cyclopenthiazide is a thiazide diuretic with antihypertensive properties. In a double blind, randomized crossover study, cyclopenthiazide was effective in reducing diastolic blood pressure in mildly hypertensive non-insulin dependent diabetic patients . It is a positive allosteric modulator at AMPA-A receptors .
Approved
Matched Iupac: … 6-chloro-3-(cyclopentylmethyl)-1,1-dioxo-3,4-dihydro-2H-1λ⁶,2,4-benzothiadiazine-7-sulfonamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... cyclopenthiazide and potassium ... cyclopenthiazide and potassium-sparing agents ... Low-Ceiling Diuretics and Potassium-Sparing Agents …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... cyclopenthiazide and potassium ... cyclopenthiazide and potassium-sparing agents ... Low-Ceiling Diuretics and Potassium-Sparing Agents …
Prednisolone acetate
Prednisolone acetate is a prednisolone molecule bound to an acetate functional group by an ester bond. Prednisolone acetate was granted FDA approval in 1955.
Approved
Vet approved
Matched Iupac: … 2-[(1R,3aS,3bS,9aR,9bS,10S,11aS)-1,10-dihydroxy-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH ... ,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-oxoethyl acetate …
Matched Mixtures name: … CONJUNTIN-S® LIQUIFILM® SUSPENSION OFTALMICA ESTERIL ... SUPRENIL STERIL OFTALMIK SUSPANSIYON 5 ML ... BLEPHAMIDE % 0,2 + % 10 GÖZ DAMLASI, SÜSPANSİYON, 5 ML …
Matched Categories: … P-glycoprotein substrates ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP3A Inducers ... Cytochrome P-450 CYP3A4 Inducers ... Cytochrome P-450 CYP3A Substrates …
Matched Products: … PRED FORTE % 1 GÖZ DAMLASI, SÜSPANSİYON, 5 ML ... Ak Tate Oph Sus 1% ... Diopred Suspension 1% …
Matched Mixtures name: … CONJUNTIN-S® LIQUIFILM® SUSPENSION OFTALMICA ESTERIL ... SUPRENIL STERIL OFTALMIK SUSPANSIYON 5 ML ... BLEPHAMIDE % 0,2 + % 10 GÖZ DAMLASI, SÜSPANSİYON, 5 ML …
Matched Categories: … P-glycoprotein substrates ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP3A Inducers ... Cytochrome P-450 CYP3A4 Inducers ... Cytochrome P-450 CYP3A Substrates …
Matched Products: … PRED FORTE % 1 GÖZ DAMLASI, SÜSPANSİYON, 5 ML ... Ak Tate Oph Sus 1% ... Diopred Suspension 1% …
Prednisolone phosphate
Prednisolone phosphate is a glucocorticoid similar to cortisol used for its anti-inflammatory, immunosuppressive, anti-neoplastic, and vasoconstrictive effects. Prednisolone phosphate was granted FDA Approval on 19 December 1973.
Approved
Vet approved
Matched Iupac: … {2-[(1R,3aS,3bS,9aR,9bS,10S,11aS)-1,10-dihydroxy-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH, ... 9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-oxoethoxy}phosphonic acid …
Matched Salts cas: … 125-02-0 …
Matched Categories: … P-glycoprotein inducers ... Cytochrome P-450 CYP2A6 Inducers ... P-glycoprotein substrates ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2B6 Inducers …
Matched Products: … METICORTELONE® SOLUCION ORAL 3 MG /ML ... XILONE Syrup 5 mg / 5 ml ... PREDNISOLONE SYRUP 5 mg/5 ml …
Matched Salts cas: … 125-02-0 …
Matched Categories: … P-glycoprotein inducers ... Cytochrome P-450 CYP2A6 Inducers ... P-glycoprotein substrates ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2B6 Inducers …
Matched Products: … METICORTELONE® SOLUCION ORAL 3 MG /ML ... XILONE Syrup 5 mg / 5 ml ... PREDNISOLONE SYRUP 5 mg/5 ml …
Ethinylestradiol
Ethinylestradiol was first synthesized in 1938 by Hans Herloff Inhoffen and Walter Hohlweg at Schering. It was developed in an effort to create an estrogen with greater oral bioavailability. These properties were achieved by the substitution of an ethinyl group at carbon 17 of estradiol. Ethinylestradiol soon replaced mestranol in...
Approved
Matched Iupac: … (1R,3aS,3bR,9bS,11aS)-1-ethynyl-11a-methyl-1H,2H,3H,3aH,3bH,4H,5H,9bH,10H,11H,11aH-cyclopenta[a]phenanthrene …
Matched Mixtures name: … Drosfemine 0,02 mg/3 mg 24+4 Filmtabletten ... YAZZ 3 MG/0.02 MG FILM KAPLI TABLET, 3×(24+4) TABLET, 28 ADET ... DROSPERA 3 MG/0.02 MG FILM KAPLI TABLET,24+4 ADET …
Matched Categories: … P-glycoprotein substrates ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP1A2 Substrates ... Cytochrome P-450 CYP3A Substrates ... Cytochrome P-450 CYP2C8 Inhibitors …
Matched Mixtures name: … Drosfemine 0,02 mg/3 mg 24+4 Filmtabletten ... YAZZ 3 MG/0.02 MG FILM KAPLI TABLET, 3×(24+4) TABLET, 28 ADET ... DROSPERA 3 MG/0.02 MG FILM KAPLI TABLET,24+4 ADET …
Matched Categories: … P-glycoprotein substrates ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP1A2 Substrates ... Cytochrome P-450 CYP3A Substrates ... Cytochrome P-450 CYP2C8 Inhibitors …
Magnesium oxide
Magnesium oxide is an inorganic compound that occurs in nature as the mineral periclase. In aqueous media combines quickly with water to form magnesium hydroxide. It is used as an antacid and mild laxative and has many nonmedicinal uses.
Approved
Matched Iupac: … magnesium(2+) oxidandiide …
Matched Mixtures name: … Calcium Magnesium 2:1 Tablets With Vitamin D ... B 6 Plus ... Pregvit Folic 4 …
Matched Categories: … Gastric Acid Lowering Agents ... Drugs for Acid Related Disorders …
Matched Mixtures name: … Calcium Magnesium 2:1 Tablets With Vitamin D ... B 6 Plus ... Pregvit Folic 4 …
Matched Categories: … Gastric Acid Lowering Agents ... Drugs for Acid Related Disorders …
Lubiprostone
Lubiprostone is a medication used in the management of idiopathic chronic constipation. A prostaglandin E1 derivative, lubiprostone is a bicyclic fatty acid that activates ClC-2 chloride channels located on the apical side of the gastrointestinal epithelial cells. Activation of these channels promotes the secretion of a chloride-rich fluid that soften...
Approved
Investigational
Matched Iupac: … 7-[(2R,4aR,5R,7aR)-2-(1,1-difluoropentyl)-2-hydroxy-6-oxo-octahydrocyclopenta[b]pyran-5-yl]heptanoic ... acid …
Matched Description: … A prostaglandin E1 derivative, lubiprostone is a bicyclic fatty acid that activates ClC-2 chloride channels …
Matched Description: … A prostaglandin E1 derivative, lubiprostone is a bicyclic fatty acid that activates ClC-2 chloride channels …
Oxyphencyclimine
Oxyphencyclimine is an anticholinergic drug (trade name Daricon) used in treating peptic ulcers.
Approved
Matched Iupac: … (1-methyl-1,4,5,6-tetrahydropyrimidin-2-yl)methyl 2-cyclohexyl-2-hydroxy-2-phenylacetate …
Matched Salts cas: … 125-52-0 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Synthetic Anticholinergics, Esters With Tertiary Amino Group …
Matched Products: … ออกซี่เฟน 5 ... ยาเม็ด อ๊อกซีเฟนไซคลีมีน (5 มก.) …
Matched Salts cas: … 125-52-0 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Synthetic Anticholinergics, Esters With Tertiary Amino Group …
Matched Products: … ออกซี่เฟน 5 ... ยาเม็ด อ๊อกซีเฟนไซคลีมีน (5 มก.) …
Cyanocobalamin
Cyanocobalamin (commonly known as Vitamin B12) is a highly complex, essential vitamin, owing its name to the fact that it contains the mineral, cobalt. This vitamin is produced naturally by bacteria , and is necessary for DNA synthesis and cellular energy production. Vitamin B12 has many forms, including the cyano-,...
Approved
Nutraceutical
Matched International brands: … Neuroforte-R …
Matched Iupac: … )-4-(2-{[(2R)-2-{[(2R,3S,4R,5S)-5-(5,6-dimethyl-1H-1,3-benzodiazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan ... [15.2.1.1^{2,5}.1^{7,10}.1^{12,15}]tricosa-5(23),6,10(22),11,15(21),16-hexaen-20-yl]cobaltylium ... -3-yl phosphonato]oxy}propyl]carbamoyl}ethyl)-1,4,6,9,9,14,16,19-octamethyl-20,21,22,23-tetraazapentacyclo ... cyano[(1R,2R,3R,4R,6Z,8S,11Z,13S,14S,16Z,18S,19S)-8,13,18-tris(2-carbamoylethyl)-3,14,19-tris(carbamoylmethyl …
Matched Mixtures name: … RUBIRON+6 AMPUL, 5 ADET ... ENJEKSİYONLUK ÇÖZELTİ İÇEREN AMPUL (1 ML VE 2 ML) X 6 AMPUL ... P-NATAL® …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds with 4 or More Rings ... Vitamin B12 and Folic Acid ... iron, vitamin B12 and folic acid …
Matched Products: … MONOVİT B12 1000 mcg/1 ml IM Enjeksiyonluk Cözelti, 5 ADET ... VİTAKOBAL 1000 MCG/1 ML İ.M. ENJEKSİYONLUK ÇÖZELTİ, 5 ADET ... VITAMINA B12 1 MG/ML INYECTABLE …
Matched Iupac: … )-4-(2-{[(2R)-2-{[(2R,3S,4R,5S)-5-(5,6-dimethyl-1H-1,3-benzodiazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan ... [15.2.1.1^{2,5}.1^{7,10}.1^{12,15}]tricosa-5(23),6,10(22),11,15(21),16-hexaen-20-yl]cobaltylium ... -3-yl phosphonato]oxy}propyl]carbamoyl}ethyl)-1,4,6,9,9,14,16,19-octamethyl-20,21,22,23-tetraazapentacyclo ... cyano[(1R,2R,3R,4R,6Z,8S,11Z,13S,14S,16Z,18S,19S)-8,13,18-tris(2-carbamoylethyl)-3,14,19-tris(carbamoylmethyl …
Matched Mixtures name: … RUBIRON+6 AMPUL, 5 ADET ... ENJEKSİYONLUK ÇÖZELTİ İÇEREN AMPUL (1 ML VE 2 ML) X 6 AMPUL ... P-NATAL® …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds with 4 or More Rings ... Vitamin B12 and Folic Acid ... iron, vitamin B12 and folic acid …
Matched Products: … MONOVİT B12 1000 mcg/1 ml IM Enjeksiyonluk Cözelti, 5 ADET ... VİTAKOBAL 1000 MCG/1 ML İ.M. ENJEKSİYONLUK ÇÖZELTİ, 5 ADET ... VITAMINA B12 1 MG/ML INYECTABLE …
Isosorbide mononitrate
Isosorbide mononitrate is an organic nitrate with vasodilating properties. It is an anti-anginal agent that works by relaxing the smooth muscles of both arteries and veins, but but predominantly veins to reduce cardiac preload.[L11698, L11743] Isosorbide mononitrate is an active metabolite of isosorbide dinitrate. Like other organic nitrates, isosorbide mononitrate...
Approved
Matched Synonyms: … IS 5-MN ... IS-5-MN ... Iso-5-mononitrate …
Matched Iupac: … (3R,3aS,6S,6aR)-6-hydroxy-hexahydrofuro[3,2-b]furan-3-yl nitrate …
Matched Products: … IS 5 MONO RATIO 20MG TAB ... IS 5 MONO RATIO 40MG RET ... IS 5 MONO RATIO 40MG TAB …
Matched Iupac: … (3R,3aS,6S,6aR)-6-hydroxy-hexahydrofuro[3,2-b]furan-3-yl nitrate …
Matched Products: … IS 5 MONO RATIO 20MG TAB ... IS 5 MONO RATIO 40MG RET ... IS 5 MONO RATIO 40MG TAB …
Moexipril
Moexipril is a non-sulfhydryl containing precursor of the active angiotensin-converting enzyme (ACE) inhibitor moexiprilat. It is used to treat high blood pressure (hypertension). It works by relaxing blood vessels, causing them to widen. Lowering high blood pressure helps prevent strokes, heart attacks and kidney problems.
Approved
Matched Iupac: … (3S)-2-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline ... -3-carboxylic acid …
Matched Salts cas: … 82586-52-5 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Salts cas: … 82586-52-5 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Doxapram
A central respiratory stimulant with a brief duration of action. (From Martindale, The Extra Pharmocopoeia, 30th ed, p1225)
Approved
Vet approved
Matched Synonyms: … 1-ethyl-4-(2-morpholinoethyl)-3,3-diphenyl-2-pyrrolidinone …
Matched Iupac: … 1-ethyl-4-[2-(morpholin-4-yl)ethyl]-3,3-diphenylpyrrolidin-2-one …
Matched Salts cas: … 7081-53-0 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … RESDOX 20 MG/ML ENJEKSİYONLUK ÇÖZELTİ, 5 ADET …
Matched Iupac: … 1-ethyl-4-[2-(morpholin-4-yl)ethyl]-3,3-diphenylpyrrolidin-2-one …
Matched Salts cas: … 7081-53-0 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … RESDOX 20 MG/ML ENJEKSİYONLUK ÇÖZELTİ, 5 ADET …
Delamanid
Delamanid is an anti-tuberculosis agent derived from the nitro-dihydro-imidazooxazole class of compounds that inhibits mycolic acid synthesis of bacterial cell wall . It is used in the treatment of multidrug-resistant and extensively drug-resistant tuberculosis (TB) in a combination regimen. Emergence of multidrug-resistant and extensively drug-resistant tuberculosis creates clinical challenges for...
Approved
Investigational
Matched Synonyms: … (R)-2-methyl-6-nitro-2-{4-[4-(4-trifluoromethoxyphenoxy)piperidin-1-yl]phenoxymethyl}-2,3-dihydroimidazo ... (2R)-2-methyl-6-nitro-2-((4-(4-(4-(trifluoromethoxy)phenoxy)piperidin-1-yl)phenoxy)methyl)-2,3-dihydroimidazo ... Imidazo(2,1-B)oxazole, 2,3-dihydro-2-methyl-6-nitro-2-((4-(4-(4-(trifluoromethoxy)phenoxy)-1-piperidinyl …
Matched Iupac: … 1-(4-{[(2R)-2-methyl-6-nitro-2H,3H-imidazo[2,1-b][1,3]oxazol-2-yl]methoxy}phenyl)-4-[4-(trifluoromethoxy …
Matched Description: … anti-tuberculosis agent derived from the nitro-dihydro-imidazooxazole class of compounds that inhibits mycolic acid ... Spontaneous resistance to delamanid was observed during treatment, where mutation in one of the 5 F420 ... Multidrug-resistant tuberculosis may also require more than 2 years of chemotherapy and second-line therapies …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP3A Substrates ... Cytochrome P-450 CYP3A4 Substrates …
Matched Iupac: … 1-(4-{[(2R)-2-methyl-6-nitro-2H,3H-imidazo[2,1-b][1,3]oxazol-2-yl]methoxy}phenyl)-4-[4-(trifluoromethoxy …
Matched Description: … anti-tuberculosis agent derived from the nitro-dihydro-imidazooxazole class of compounds that inhibits mycolic acid ... Spontaneous resistance to delamanid was observed during treatment, where mutation in one of the 5 F420 ... Multidrug-resistant tuberculosis may also require more than 2 years of chemotherapy and second-line therapies …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP3A Substrates ... Cytochrome P-450 CYP3A4 Substrates …
Finerenone
Finerenone, or BAY 94-8862, is a mineralocorticoid receptor antagonist indicated to reduce the risk of sustained decline in glomerular filtration rate, end stage kidney disease, cardiovascular death, heart attacks, and hospitalization due to heart failure in adults with chronic kidney disease associated with type II diabetes mellitus.[A236519,L34739] Patients with kidney...
Approved
Investigational
Matched Iupac: … (4S)-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2C8 Substrates ... Cytochrome P-450 CYP3A Substrates ... Cytochrome P-450 CYP3A4 Substrates …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2C8 Substrates ... Cytochrome P-450 CYP3A Substrates ... Cytochrome P-450 CYP3A4 Substrates …
Diclofenac
Diclofenac is a phenylacetic acid derivative and non-steroidal anti-inflammatory drug (NSAID).[label] NSAIDs inhibit cyclooxygenase (COX)-1 and-2 which are the enzyme responsible for producing prostaglandins (PGs). PGs contribute to inflammation and pain signalling. Diclofenac, like other NSAIDs, is often used as first line therapy for acute and chronic pain and inflammation...
Approved
Vet approved
Matched Synonyms: … 2-((2,6-dichlorophenyl)amino)benzeneacetic acid ... [2-(2,6-dichloroanilino)phenyl]acetic acid ... Diclofenac acid …
Matched Iupac: … 2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid …
Matched Description: … [label] NSAIDs inhibit cyclooxygenase (COX)-1 and-2 which are the enzyme responsible for producing prostaglandins ... Diclofenac is a phenylacetic acid derivative and non-steroidal anti-inflammatory drug (NSAID). ... Diclofenac was the product of rational drug design based on the structures of [phenylbutazone], [mefenamic acid …
Matched Salts cas: … 81811-14-5 ... 15307-81-0 ... 15307-79-6 ... 119623-66-4 …
Matched Mixtures name: … Calcipotriene 0.005% / Diclofenac Sodium 3% / Hyaluronic Acid Sodium Salt 2% / Niacinamide 2% ... AFTOJEL % 0,1 + %3 JEL (5 G) ... Diclo Gel 1% Pak …
Matched Salts name: … Diclofenac potassium …
Matched Categories: … Carboxylic Acids ... Cyclooxygenase-2 (COX-2) Inhibitors ... Heteroaryl acetic acid NSAIDS ... Acetic Acid Derivatives and Related Substances ... Non COX-2 selective NSAIDS …
Matched Products: … Diclofenac Sodium 3% / Hyaluronic Acid Sodium Salt 2% / Niacinamide 4% ... DIKLO-S %4 SPREY JEL, 25 GR ... DIKLO-S %4 SPREY JEL, 7,5 GR …
Matched Iupac: … 2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid …
Matched Description: … [label] NSAIDs inhibit cyclooxygenase (COX)-1 and-2 which are the enzyme responsible for producing prostaglandins ... Diclofenac is a phenylacetic acid derivative and non-steroidal anti-inflammatory drug (NSAID). ... Diclofenac was the product of rational drug design based on the structures of [phenylbutazone], [mefenamic acid …
Matched Salts cas: … 81811-14-5 ... 15307-81-0 ... 15307-79-6 ... 119623-66-4 …
Matched Mixtures name: … Calcipotriene 0.005% / Diclofenac Sodium 3% / Hyaluronic Acid Sodium Salt 2% / Niacinamide 2% ... AFTOJEL % 0,1 + %3 JEL (5 G) ... Diclo Gel 1% Pak …
Matched Salts name: … Diclofenac potassium …
Matched Categories: … Carboxylic Acids ... Cyclooxygenase-2 (COX-2) Inhibitors ... Heteroaryl acetic acid NSAIDS ... Acetic Acid Derivatives and Related Substances ... Non COX-2 selective NSAIDS …
Matched Products: … Diclofenac Sodium 3% / Hyaluronic Acid Sodium Salt 2% / Niacinamide 4% ... DIKLO-S %4 SPREY JEL, 25 GR ... DIKLO-S %4 SPREY JEL, 7,5 GR …
Dorzolamide
Dorzolamide is a non-bacteriostatic sulfonamide derivative and topical carbonic anhydrase (CA) inhibitor that treats elevated intraocular pressure (IOP) associated with open-angle glaucoma and ocular hypertension. It works by blocking an enzyme in the ciliary process that regulates ion balance and fluid pressure in the eyes. Unlike oral CA inhibitors, dorzolamide...
Approved
Matched Synonyms: … 4-Ethylamino-6-methyl-7,7-dioxo-4,5,6,7-tetrahydro-7lambda*6*-thieno[2,3-b]thiopyran-2-sulfonic acid ... 4-ethylamino-6-methyl-7,7-dioxo-4,5,6,7-tetrahydro-7lambda6-thieno[2,3-b]thiopyran-2-sulfonic acid amide ... (4S,6S)-4-ethylamino-6-methyl-7,7-dioxo-4,5,6,7-tetrahydro-7lambda*6*-thieno[2,3-b]thiopyran-2-sulfonic …
Matched Iupac: … (2S,4S)-4-(ethylamino)-2-methyl-1,1-dioxo-2H,3H,4H-1lambda6-thieno[2,3-b]thiopyran-6-sulfonamide …
Matched Description: … [A1303] Unlike oral CA inhibitors, dorzolamide has negligible effects of acid-base or electrolyte disturbances …
Matched Salts cas: … 130693-82-2 …
Matched Mixtures name: … XOLATIM %2+ %0,5 GÖZ DAMLASI, ÇÖZELTİ ,5 ML,1 ŞİŞE ... TOMEC %2 + %0.5 STERIL OFTALMIK ÇÖZELTİ, 6 ML ... ARUDOR % 2 + % 0.5 GOZ DAMLASI, 5 ML …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2C9 Substrates ... Cytochrome P-450 CYP2E1 Substrates …
Matched Products: … XOLADOR %2 GÖZ DAMLASI ,5 ML, 1 ŞIŞE ... DORZAMED %2 GÖZ DAMLASI ,1 ŞIŞE ... DORZOVISION(R) DORZOLAMIDA 2 % SOLUCION OFTALMICA ESTERIL …
Matched Iupac: … (2S,4S)-4-(ethylamino)-2-methyl-1,1-dioxo-2H,3H,4H-1lambda6-thieno[2,3-b]thiopyran-6-sulfonamide …
Matched Description: … [A1303] Unlike oral CA inhibitors, dorzolamide has negligible effects of acid-base or electrolyte disturbances …
Matched Salts cas: … 130693-82-2 …
Matched Mixtures name: … XOLATIM %2+ %0,5 GÖZ DAMLASI, ÇÖZELTİ ,5 ML,1 ŞİŞE ... TOMEC %2 + %0.5 STERIL OFTALMIK ÇÖZELTİ, 6 ML ... ARUDOR % 2 + % 0.5 GOZ DAMLASI, 5 ML …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Cytochrome P-450 Substrates ... Cytochrome P-450 CYP2C9 Substrates ... Cytochrome P-450 CYP2E1 Substrates …
Matched Products: … XOLADOR %2 GÖZ DAMLASI ,5 ML, 1 ŞIŞE ... DORZAMED %2 GÖZ DAMLASI ,1 ŞIŞE ... DORZOVISION(R) DORZOLAMIDA 2 % SOLUCION OFTALMICA ESTERIL …
Anileridine
Anileridine is a synthetic opioid and strong analgesic medication. It is a narcotic pain reliever used to treat moderate to severe pain. Narcotic analgesics act in the central nervous system (CNS) to relieve pain. Some of their side effects are also caused by actions in the CNS.
Approved
Illicit
Matched Synonyms: … 1-[2-(4-aminophenyl)ethyl]-4-phenyl-4-piperidinecarboxlic acid ethyl ester ... ethyl 1-(2-(4-aminophenyl)ethyl)-4-phenyl-4-piperidinecarboxylate ... ethyl 1-(p-aminophenethyl)-4-phenylisonipecotate …
Matched Iupac: … ethyl 1-[2-(4-aminophenyl)ethyl]-4-phenylpiperidine-4-carboxylate …
Matched Salts cas: … 126-12-5 ... 1976-75-6 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … ethyl 1-[2-(4-aminophenyl)ethyl]-4-phenylpiperidine-4-carboxylate …
Matched Salts cas: … 126-12-5 ... 1976-75-6 …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Tocainide
An antiarrhythmic agent which exerts a potential- and frequency-dependent block of sodium channels.
Approved
Matched Synonyms: … 2-Amino-2',6'-propionoxylidide ... 2-amino-N-(2,6-dimethylphenyl)propanamide ... 2-Amino-N-(2,6-dimethylphenyl)propionamid …
Matched Iupac: … 2-amino-N-(2,6-dimethylphenyl)propanamide …
Matched Salts cas: … 71395-14-7 …
Matched Categories: … Cytochrome P-450 Substrates ... Cytochrome P-450 CYP1A2 Inhibitors ... Cytochrome P-450 CYP1A2 Substrates ... Cytochrome P-450 Enzyme Inhibitors ... Cytochrome P-450 CYP1A2 Inhibitors (weak) …
Matched Iupac: … 2-amino-N-(2,6-dimethylphenyl)propanamide …
Matched Salts cas: … 71395-14-7 …
Matched Categories: … Cytochrome P-450 Substrates ... Cytochrome P-450 CYP1A2 Inhibitors ... Cytochrome P-450 CYP1A2 Substrates ... Cytochrome P-450 Enzyme Inhibitors ... Cytochrome P-450 CYP1A2 Inhibitors (weak) …
Brimonidine
Brimonidine is an alpha-adrenergic agonist and 2-imidazoline derivative that was first introduced in 1996. It is considered to be a third generation alpha-2 aadrenergic receptor agonist, since it displays preferential binding at alpha-2 adrenoceptors over alpha-1 receptors. Brimonidine displays a higher selectivity toward the alpha-2 adrenergic receptors than clonidine or...
Approved
Matched Synonyms: … 5-Bromo-6-(2-imidazolin-2-ylamino)quinoxaline …
Matched Iupac: … 5-bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine …
Matched Description: … preferential binding at alpha-2 adrenoceptors over alpha-1 receptors. ... ] or [apraclonidine], which are also alpha-2 adrenergic agonists. ... Brimonidine is an alpha-adrenergic agonist and 2-imidazoline derivative that was first introduced in …
Matched Salts cas: … 70359-46-5 …
Matched Mixtures name: … Brimonidine Tartrate 0.25% / Ivermectin 1% / Metronidazole 1% / Niacinamide 4% ... BRİMO-TİM 2 MG+5 MG/ML STERİL GÖZ DAMLASI, ÇÖZELTİ, 5 ML ... Combigan 2 mg/ml + 5 mg/ml Augentropfen …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Adrenergic alpha-2 Receptor Agonists …
Matched Products: … BREMON %0.2 GÖZ DAMLASI,5 ML, 1 ŞIŞE ... Brimonidine Tartrate 0.25% / Potassium Azeloyl Diglycinate 8% ... RİMONAL P %0.15 GÖZ DAMLASI, ÇÖZELTİ, 5 ML …
Matched Iupac: … 5-bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine …
Matched Description: … preferential binding at alpha-2 adrenoceptors over alpha-1 receptors. ... ] or [apraclonidine], which are also alpha-2 adrenergic agonists. ... Brimonidine is an alpha-adrenergic agonist and 2-imidazoline derivative that was first introduced in …
Matched Salts cas: … 70359-46-5 …
Matched Mixtures name: … Brimonidine Tartrate 0.25% / Ivermectin 1% / Metronidazole 1% / Niacinamide 4% ... BRİMO-TİM 2 MG+5 MG/ML STERİL GÖZ DAMLASI, ÇÖZELTİ, 5 ML ... Combigan 2 mg/ml + 5 mg/ml Augentropfen …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Adrenergic alpha-2 Receptor Agonists …
Matched Products: … BREMON %0.2 GÖZ DAMLASI,5 ML, 1 ŞIŞE ... Brimonidine Tartrate 0.25% / Potassium Azeloyl Diglycinate 8% ... RİMONAL P %0.15 GÖZ DAMLASI, ÇÖZELTİ, 5 ML …
Furosemide
Furosemide is a potent loop diuretic that acts on the kidneys to ultimately increase water loss from the body. It is an anthranilic acid derivative. Furosemide is used for edema secondary to various clinical conditions, such as congestive heart failure exacerbation, liver failure, renal failure, and high blood pressure. It...
Approved
Vet approved
Matched Synonyms: … 2-Furfurylamino-4-chloro-5-sulfamoylbenzoic acid ... 4-Chloro-N-(2-furylmethyl)-5-sulfamoylanthranilic acid ... 4-Chloro-5-sulfamoyl-N-furfuryl-anthranilic acid …
Matched Iupac: … 4-chloro-2-{[(furan-2-yl)methyl]amino}-5-sulfamoylbenzoic acid …
Matched Description: … It is an anthranilic acid derivative. …
Matched Salts cas: … 41733-55-5 …
Matched Mixtures name: … Lasitace 5 mg/40 mg Kapseln ... Lasitace 5 mg/20 mg Kapseln …
Matched Categories: … Carboxylic Acids ... furosemide and potassium ... Non Potassium Sparing Diuretics ... furosemide and potassium-sparing agents ... Sodium Potassium Chloride Symporter Inhibitors …
Matched Products: … FUROSON 40 MG/4 ML IM/IV AMPUL, 5 ADET ... FUROSEMIDE FARMA 1 ... Lasix 40 mg/4 ml Ampullen …
Matched Iupac: … 4-chloro-2-{[(furan-2-yl)methyl]amino}-5-sulfamoylbenzoic acid …
Matched Description: … It is an anthranilic acid derivative. …
Matched Salts cas: … 41733-55-5 …
Matched Mixtures name: … Lasitace 5 mg/40 mg Kapseln ... Lasitace 5 mg/20 mg Kapseln …
Matched Categories: … Carboxylic Acids ... furosemide and potassium ... Non Potassium Sparing Diuretics ... furosemide and potassium-sparing agents ... Sodium Potassium Chloride Symporter Inhibitors …
Matched Products: … FUROSON 40 MG/4 ML IM/IV AMPUL, 5 ADET ... FUROSEMIDE FARMA 1 ... Lasix 40 mg/4 ml Ampullen …
Chloric acid
Approved
Experimental
Matched Name: … Chloric acid …
Matched Iupac: … chloric acid …
Matched Salts name: … Potassium chlorate …
Matched Products: … Hemodialysis Acid Concentrate …
Matched Iupac: … chloric acid …
Matched Salts name: … Potassium chlorate …
Matched Products: … Hemodialysis Acid Concentrate …
Displaying drugs 176 - 200 of 332 in total