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Displaying drugs 176 - 200 of 14461 in total

Quazepam

Quazepam is a trifluoroethyl benzodiazepine derivative. It was first approved in the US in 1985 and is used as a hypnotic for the treatment of insomnia. It appears to be unique amongst other benzodiazepine derivatives in its relatively high affinity for sleep-promoting α1 subunit-containing GABAA receptors and low affinity for...
Approved
Illicit
Matched Description: … It was first approved in the US in 1985 and is used as a hypnotic for the treatment of insomnia. ... in its relatively high affinity for sleep-promoting α1 subunit-containing GABAA receptors and …
Matched Categories: … Hypnotics and Sedatives ... Benzodiazepine hypnotics and sedatives ... Benzodiazepines and benzodiazepine derivatives …

Oxazepam

Oxazepam is an intermediate-acting, 3-hydroxybenzodiazepine used in the treatment of alcohol withdrawal and anxiety disorders. Oxazepam, like related 3-hydroxybenzodiazepine lorazepam, is considered less susceptible to pharmacokinetic variability based on patient-specific factors (e.g. age, liver disease) - this feature is advantageous as compared to other benzodiazepines, and is likely owing in...
Approved
Matched Description: … [A203516] It is an active metabolite of both [diazepam] and [temazepam][A39486] and undergoes very little ... Oxazepam is an intermediate-acting, 3-hydroxybenzodiazepine used in the treatment of alcohol withdrawal and ... factors (e.g. age, liver disease) - this feature is advantageous as compared to other benzodiazepines, and …
Matched Categories: … Hypnotics and Sedatives ... Benzodiazepine hypnotics and sedatives ... Benzodiazepines and benzodiazepine derivatives …

Trimebutine

Trimebutine is a spasmolytic agent that regulates intestinal and colonic motility and relieves abdominal pain with antimuscarinic and weak mu opioid agonist effects. It is marketed for the treatment of irritable bowel syndrome (IBS) and lower gastrointestinal tract motility disorders, with IBS being one of the most common multifactorial GI...
Approved
Matched Description: … Trimebutine is a spasmolytic agent that regulates intestinal and colonic motility and relieves abdominal ... pain with antimuscarinic and weak mu opioid agonist effects. ... Trimebutine is not a FDA-approved drug, but it is available in Canada and several other international …
Matched Categories: … Alimentary Tract and Metabolism …

Flecainide

Flecainide is a Class I anti-arrhythmic agent like encainide and propafenone. Flecainide’s development began in 1966 and was first synthesized in 1972 as an attempt to generate new anesthetics. It is used to prevent supraventricular and ventricular arrhythmias, as well as paroxysmal atrial fibrillation and flutter.[L8878,L5056] Flecainide was granted FDA...
Approved
Withdrawn
Matched Description: … fibrillation and flutter. ... Flecainide is a Class I anti-arrhythmic agent like [encainide] and [propafenone]. ... [A186880] Flecainide’s development began in 1966 and was first synthesized in 1972 as an attempt to generate …

Hetacillin

Hetacillin is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually gram-positive, organisms. The name "penicillin" can either refer to several variants of penicillin available, or to the group of antibiotics derived from the penicillins. Hetacillin has in vitro activity against gram-positive and gram-negative...
Approved
Vet approved
Withdrawn
Matched Description: … Hetacillin has in vitro activity against gram-positive and gram-negative aerobic and anaerobic bacteria ... The bactericidal activity of Hetacillin results from the inhibition of cell wall synthesis and is mediated …
Matched Salts name: … Hetacillin potassium …

Triazolam

Withdrawn in the United Kingdom due to risk of psychiatric adverse drug reactions. This drug continues to be available in the U.S. Internationally, triazolam is a Schedule IV drug under the Convention on Psychotropic Substances.
Approved
Investigational
Matched Categories: … Hypnotics and Sedatives ... Benzodiazepine hypnotics and sedatives ... Benzodiazepines and benzodiazepine derivatives …

Halothane

A nonflammable, halogenated, hydrocarbon anesthetic that provides relatively rapid induction with little or no excitement. Analgesia may not be adequate. nitrous oxide is often given concomitantly. Because halothane may not produce sufficient muscle relaxation, supplemental neuromuscular blocking agents may be required. (From AMA Drug Evaluations Annual, 1994, p178)
Approved
Vet approved

Calcium glycerophosphate

Calcium glycerophosphate is a DB01373 salt of glycerophosphoric acid that forms a white, fine, slightly hygroscopic powder. The commercial product is a mixture of calcium beta-, and D-, and L -alpha-glycerophosphate. By FDA, calcium glycerophosphate is considered a generally recognized as safe (GRAS) food ingredient as a nutrient supplement (source...
Approved
Matched Description: … The commercial product is a mixture of calcium beta-, and D-, and L -alpha-glycerophosphate. ... phosphate levels and direct interaction with dental mineral [A27153]. ... suggested that calcium glycerophosphate promotes plaque-pH buffering, elevation of plaque [DB01373] and …
Matched Mixtures name: … Somarexin and C 1000 ... NUTROPLEX LIQUID WITH IRON AND LYSINE …

Magnesium gluconate

Magnesium gluconate is a magnesium salt of gluconate. It demonstrates the highest oral bioavailability of magnesium salts and is used as a mineral supplement. Magnesium is ubiquitous in the human body, and is naturally present in many foods, added to other food products, available as a dietary supplement and used...
Approved
Investigational
Matched Description: … Although magnesium is available in the form of sulphates, lactate, hydroxide, oxide and chloride, only ... and laxatives) [L2601]. ... It demonstrates the highest oral bioavailability of magnesium salts [L2608] and is used as a mineral …
Matched Mixtures name: … NUTROPLEX LIQUID WITH IRON AND LYSINE …
Matched Categories: … Alimentary Tract and Metabolism …

Fluoxymesterone

An anabolic steroid that has been used in the treatment of male hypogonadism, delayed puberty in males, and in the treatment of breast neoplasms in women.
Approved
Illicit
Matched Description: … anabolic steroid that has been used in the treatment of male hypogonadism, delayed puberty in males, and …
Matched Categories: … Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Nitrous acid

Nitrous acid (as sodium nitrite) is used as part of an intravenous mixture with sodium thiosulfate to treat cyanide poisoning. It is on the World Health Organization's List of Essential Medicines, a list of the most important medications needed in a basic health system. There is also research to investigate...
Approved
Investigational
Matched Description: … applicability towards treatments for heart attacks, brain aneurysms, pulmonary hypertension in infants, and …
Matched Salts name: … Potassium nitrite …
Matched Categories: … Indicators and Reagents ... Diet, Food, and Nutrition …

Isoflurane

A stable, non-explosive inhalation anesthetic, relatively free from significant side effects.
Approved
Vet approved

Ipratropium

Ipratropium is a quaternary ammonium derivative of atropine that acts as an anticholinergic agent. It is commonly administered through inhalation which allows producing a local effect without presenting a significant systemic absorption. Ipratropium as a therapeutic agent was developed by Boehringer Ingelheim and its first monotherapy product was FDA approved...
Approved
Experimental
Matched Description: … product was FDA approved in 1986, while the combination product of ipratropium and [albuterol] was approved ... [A176957] Ipratropium as a therapeutic agent was developed by Boehringer Ingelheim and its first monotherapy …
Matched Mixtures name: … Ipratropium Bromide and Albuterol Sulfate ... Ipratropium Bromide and Albuterol Sulfate ... Ipratropium Bromide and Albuterol Sulfate …
Matched Salts name: … Ipratropium chloride ... Ipratropium bromide monohydrate …
Matched Categories: … fenoterol and ipratropium bromide ... salbutamol and ipratropium bromide …

Mitotane

Mitotane is an adrenolytic isomer of the insecticide dichlorodiphenyldichloroethane (DDD) - itself a metabolite of dichlorodiphenyltrichloroethane (DDT) - that inhibits cells of the adrenal cortex and their production of hormones. It has been in use since 1959 for the treatment of inoperable adrenocortical carcinoma and is used off-label for the...
Approved
Matched Description: … It has been in use since 1959 for the treatment of inoperable adrenocortical carcinoma[A263010] and is ... itself a metabolite of dichlorodiphenyltrichloroethane (DDT) - that inhibits cells of the adrenal cortex and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …

Rabeprazole

Rabeprazole is an antiulcer drug in the class of proton pump inhibitors. It is a prodrug - in the acid environment of the parietal cells it turns into active sulphenamide form. Rabeprazole inhibits the H+, K+ATPase of the coating gastric cells and dose-dependent oppresses basal and stimulated gastric acid secretion.
Approved
Investigational
Matched Description: … and stimulated gastric acid secretion. ... Rabeprazole inhibits the H+, K+ATPase of the coating gastric cells and dose-dependent oppresses basal …
Matched Categories: … Alimentary Tract and Metabolism ... Antiinflammatory and Antirheumatic Products ... rabeprazole, amoxicillin and metronidazole ... rabeprazole, amoxicillin and clarithromycin ... Topical Products for Joint and Muscular Pain …

Oxyphencyclimine

Oxyphencyclimine is an anticholinergic drug (trade name Daricon) used in treating peptic ulcers.
Approved
Matched Categories: … Alimentary Tract and Metabolism ... oxyphencyclimine and psycholeptics …

Beclomethasone dipropionate

Beclomethasone dipropionate is a second-generation synthetic corticosteroid and diester of beclomethasone, which is structurally similar to dexamethasone. It is a prodrug of an active metabolite beclomethasone 17-monopropionate (17-BMP) which acts on the glucocorticoid receptor to mediates its therapeutic action. Beclomethasone dipropionate itself posesses weak glucocorticoid receptor binding affinity and is...
Approved
Investigational
Matched Description: … later in a dry powder inhaler and an aqueous nasal spray. ... Beclomethasone dipropionate is a second-generation[A179842] synthetic corticosteroid and diester of beclomethasone ... Beclomethasone dipropionate became first available in a pressurized metered-dose inhaler in 1972 and …
Matched Mixtures name: … Ibicar S (Salbutamol 100 mcg/actuation and Beclometasone 50 mcg/actuation) Pressurised Inhalation …
Matched Salts name: … Beclomethasone dipropionate monohydrate …
Matched Categories: … Alimentary Tract and Metabolism ... formoterol and beclometasone ... salbutamol and beclometasone ... beclometasone and antibiotics ... formoterol, glycopyrronium bromide and beclometasone …

Digitoxin

A cardiac glycoside sometimes used in place of digoxin. It has a longer half-life than digoxin; toxic effects, which are similar to those of digoxin, are longer lasting. (From Martindale, The Extra Pharmacopoeia, 30th ed, p665)
Approved
Investigational

Cloxacillin

A semi-synthetic penicillin antibiotic which is a chlorinated derivative of oxacillin.
Approved
Investigational
Vet approved

Dronedarone

Dronedarone is a Class III antiarrhythmic drug that works to restore the normal sinus rhythm in patients with paroxysmal or persistent atrial fibrillation. Atrial fibrillation is a common sustained arrhythmia where the treatment primarily focuses on stroke prevention and symptom management. It is managed by rate control, rhythm control, prevention...
Approved
Matched Description: … A186071] It meets criteria of all four Vaughan Williams antiarrhythmic drug classes by blocking sodium, potassium ... , and calcium ion channels and inhibiting β-adrenergic receptors. ... toxicities, such as thyroid and pulmonary toxicities. …

Cyanocobalamin

Cyanocobalamin (commonly known as Vitamin B12) is a highly complex, essential vitamin, owing its name to the fact that it contains the mineral, cobalt. This vitamin is produced naturally by bacteria , and is necessary for DNA synthesis and cellular energy production. Vitamin B12 has many forms, including the cyano-,...
Approved
Nutraceutical
Matched Description: … This vitamin is produced naturally by bacteria [A175276], and is necessary for DNA synthesis and cellular ... Vitamin B12 has many forms, including the cyano-, methyl-, deoxyadenosyl- and hydroxy-cobalamin forms ... The _cyano_ form, is the most widely used form in supplements and prescription drugs [A175255], [FDA …
Matched Mixtures name: … Isotonix Advanced B-complex Vitamins With Potassium and Magnesium ... and Succinic Acid ... Somarexin and C 1000 …
Matched Categories: … Diet, Food, and Nutrition ... Blood and Blood Forming Organs ... Vitamin B12 and Folic Acid ... iron, vitamin B12 and folic acid …

Ivabradine

Ivabradine is a novel heart rate lowering medicine for the symptomatic management of stable angina pectoralis and symptomatic chronic heart failure. Ivabradine, brand name Corlanor, was approved by the FDA in April 2015 for the treatment of chronic heart failure in patients with an ejection fraction of ≤35%, in sinus...
Approved
Matched Description: … is a novel heart rate lowering medicine for the symptomatic management of stable angina pectoralis and ... Although non-dihydropyridine calcium channel blockers and beta blockers also effectively lower heart ... pacemaker current (If) in the sinoatrial node in a dose-dependent fashion, resulting in a lower heart rate and …
Matched Categories: … metoprolol and ivabradine ... carvedilol and ivabradine …

Chloroform

Chloroform is an organic small molecule, member of the family of the chloromethanes that presents a formula of CHCl3. It is a colorless, sweet-smelling, dense liquid that is produced on a large scale as a precursor to PTFE and refrigerants, but the latter application is declining. Chloroform is part of...
Approved
Vet approved
Withdrawn
Matched Description: … a colorless, sweet-smelling, dense liquid that is produced on a large scale as a precursor to PTFE and …

Cefotaxime

Cefotaxime is a third-generation cephalosporin antibiotic. Like other third-generation cephalosporins, it has broad spectrum activity against Gram positive and Gram negative bacteria. In most cases, it is considered to be equivalent to ceftriaxone in terms of safety and efficacy. Cefotaxime sodium is marketed under various trade names including Claforan (Sanofi-Aventis).
Approved
Matched Description: … Like other third-generation cephalosporins, it has broad spectrum activity against Gram positive and ... In most cases, it is considered to be equivalent to ceftriaxone in terms of safety and efficacy. …
Matched Products: … Cefotaxime and Dextrose …

Rocuronium

Rocuronium (rapid onset-curonium) is a desacetoxy analogue of vecuronium with a more rapid onset of action. It is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia, to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation. Introduced in 1994, rocuronium has...
Approved
Matched Description: … It is commonly marketed under the trade names Zemuron and Esmeron. ... Introduced in 1994, rocuronium has rapid onset, and intermediate duration of action. ... neuromuscular blocker or muscle relaxant used in modern anaesthesia, to facilitate endotracheal intubation and …
Displaying drugs 176 - 200 of 14461 in total