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Displaying drugs 226 - 250 of 14564 in total
Approved
Experimental
Matched Mixtures name: … Re-Lieved 3 in 1 Patch ... Arctic Blast Pain Releiving ... Cho-A Point Plaster …
Matched Products: … CBD Clinic - Massage Oil - Level 1
Magnesium citrate is a low volume and osmotic cathartic agent. The cathartic action works primarily through the high osmolarity of the solution which draws large amounts of fluid into space where is used. Magnesium citrate is considered by the FDA as an approved inactive ingredient for approved drug products under...
Approved
Matched Description: … products under the specifications of oral administration of a maximum concentration of 237 mg. ... [L2831] It is also considered as an active ingredient in over-the-counter products.[L1113] ... [T215] Magnesium citrate is considered by the FDA as an approved inactive ingredient for approved drug …
Matched Products: … Citrate of Magnesium …
Zavegepant (BHV-3500) is a calcitonin gene-related peptide (CGRP) receptor antagonist. CGRP is released from sensory nerves and acts as a strong vasodilator, and thanks to these properties, it is involved in pain pathways. CGRP receptors are expressed in the central and peripheral nervous system; however, CGRP does not cross the...
Approved
Investigational
Matched Synonyms: … )-2-(4-(1-methyl-4-piperidinyl)-1-piperazinyl)-2-oxoethyl)- ... 1-piperidinecarboxamide, 4-(1,2-dihydro-2-oxo-3-quinolinyl)-n-((1r)-1-((7-methyl-1h-indazol-5-yl)methyl …
Matched Iupac: … N-[(2R)-3-(7-methyl-1H-indazol-5-yl)-1-[4-(1-methylpiperidin-4-yl)piperazin-1-yl]-1-oxopropan-2-yl]-4 ... -(2-oxo-1,2-dihydroquinolin-3-yl)piperidine-1-carboxamide …
Matched Description: … Zavegepant (BHV-3500) is a calcitonin gene-related peptide (CGRP) receptor antagonist. ... is beneficial in the treatment of migraine. ... [A258190,A258195] In March 2023, the FDA approved the use of zavegepant nasal spray for the acute treatment …
Matched Categories: … MATE 1 Substrates ... Heterocyclic Compounds, 1-Ring ... Calcitonin Gene-Related Peptide (CGRP) Antagonists ... Calcitonin Gene-Related Peptide Receptor Antagonists ... Receptors, Calcitonin Gene-Related Peptide, antagonists & inhibitors …
Typhoid Vi polysaccharide vaccine is a vaccine that is administered intramuscularly. It is an active immunization for the prevention of typhoid fever caused by S typhi and is approved for use in persons two years of age or older. The vaccine contains the purified cell surface Vi polysaccharide extracted from...
Approved
Matched Description: … It is an active immunization for the prevention of typhoid fever caused by S typhi and is approved for ... use in persons two years of age or older. ... The bacterial culture is inactivated in the medium with the capsular polysaccharides precipated from …
Matched Products: … TYPHIM VI 0,5 ML IM/SC ENJEKSİYON İÇİN ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET ... Typhim VI Solution for Injection in Multidose ... Typhim Vi Injektionslösung in einer Fertigspritze …
Arsenic trioxide is a chemotherapeutic agent of idiopathic function used to treat leukemia that is unresponsive to first line agents. It is suspected that arsenic trisulfide induces cancer cells to undergo apoptosis. In general, arsenic is known to be a naturally toxic substance capable of eliciting a variety of dangerous...
Approved
Investigational
Matched Description: … In general, arsenic is known to be a naturally toxic substance capable of eliciting a variety of dangerous ... The enzyme thioredoxin reductase has recently been identified as a target for arsenic trioxide. ... Arsenic trioxide is a chemotherapeutic agent of idiopathic function used to treat leukemia that is unresponsive …
Matched Products: … อะซาดิน 1 มก. / มล. ... TRISENOX 1 MG/1 ML IV INFÜZYON IÇIN KONSANTRE ÇÖZELTI IÇEREN AMPUL, 10 ADET ... Arsentrioxid Sandoz 1 mg/ml - Konzentrat zur Herstellung einer Infusionslösung …
A small colorless crystal used as an anticonvulsant, a cathartic, and an electrolyte replenisher in the treatment of pre-eclampsia and eclampsia. It causes direct inhibition of action potentials in myometrial muscle cells. Excitation and contraction are uncoupled, which decreases the frequency and force of contractions. (From AMA Drug Evaluations Annual,...
Approved
Investigational
Vet approved
Matched Synonyms: … Magnesium sulfate (1:1) …
Matched Description: … A small colorless crystal used as an anticonvulsant, a cathartic, and an electrolyte replenisher in the ... It causes direct inhibition of action potentials in myometrial muscle cells. ... Excitation and contraction are uncoupled, which decreases the frequency and force of contractions. …
Matched Salts cas: … 14168-73-1
Matched Mixtures name: … Magnesium Sulfate In 5% Dextrose Inj(20mg/ml) …
Matched Products: … Magnesium Sulfate in Water ... Magnesium Sulfate in Dextrose ... Magnesium Sulfate In Dextrose …
Iodide I-131 (as Sodium iodide I-131) is a radioisotopic drug used for the treatment and palliation of thyroid malignancy. Iodine-131 is notable for causing mutation and death in cells that it penetrates, which is due to its mode of beta decay. As a result of beta decay, approximately 10% of...
Approved
Investigational
Matched Description: … Iodide I-131 (as Sodium iodide I-131) is a radioisotopic drug used for the treatment and palliation of ... As a result of beta decay, approximately 10% of its energy and radiation dose is via gamma radiation, ... It is also indicated for use in performance of the radioactive iodide (RAI) uptake test to evaluate thyroid …
Matched Products: … IOKAM BHR I-131 ORAL KAPSÜL ,1 ADET ... IOKAM BHR I-131 ORAL ÇÖZELTI ,1 ADET ... MON.IYOT-131 74-18500 MBQ ORAL ÇÖZELTİ İÇEREN FLAKON, 1 MCİ …
Sodium ferric gluconate complex is an iron replacement product for treatment of iron deficiency anemia. The stable macromolecular complex is negatively charged at alkaline pH with an apparent molecular weight of 289,000 – 440,000 daltons on gel chromatography. It is composed of iron (III) oxide hydrate directly bonded to sucrose...
Approved
Matched Description: … in a molar ratio of two iron molecules to one gluconate. ... It is used in adult and in pediatric patients over the age of 6 years with chronic kidney disease (CKD ... It is composed of iron (III) oxide hydrate directly bonded to sucrose with a chelating gluconate function …
Matched Products: … Sodium Ferric Gluconate Complex in Sucrose …
An essential amino acid that is necessary for normal growth in infants and for nitrogen balance in adults. It is a precursor of indole alkaloids in plants. It is a precursor of serotonin (hence its use as an antidepressant and sleep aid). It can be a precursor to niacin, albeit...
Approved
Nutraceutical
Withdrawn
Matched Description: … It is a precursor of indole alkaloids in plants. ... It is a precursor of serotonin (hence its use as an antidepressant and sleep aid). ... It can be a precursor to niacin, albeit inefficiently, in mammals. …
Matched Mixtures name: … AMINOMIX 1 NOVUM 1500 ML ... Aminomix 1 Novum - Infusionslösung ... AMINOMIX 1 INTRAVENÖZ İNZFÜZYON, 1000 ML …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
Approved
Matched Iupac: … )amino)ethan-1-ol ... 2-({6-[bis(2-hydroxyethyl)amino]-4,8-bis(piperidin-1-yl)-[1,3]diazino[5,4-d]pyrimidin-2-yl}(2-hydroxyethyl …
Matched Description: … A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular ... Dipyridamole also potentiates the antiaggregating action of prostacyclin. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Imidazole derivative anesthetic and hypnotic with little effect on blood gases, ventilation, or the cardiovascular system. It has been proposed as an induction anesthetic.
Approved
Matched Synonyms: … R-(+)-ethyl 1-(1-phenylethyl)-1H-imidazole-5-carboxylate ... (R)-1-(1-phenylethyl)-1H-imidazole-5-carboxylic acid ethyl ester ... (+)-ethyl 1-(α-methylbenzyl)imidazole-5-carboxylate …
Matched Iupac: … ethyl 1-[(1R)-1-phenylethyl]-1H-imidazole-5-carboxylate …
Matched Description: … Imidazole derivative anesthetic and hypnotic with little effect on blood gases, ventilation, or the cardiovascular …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … ETOMIDATE-LIPURO 20MG/10ML INJ IN 10ML GA …
The plasma protein fraction human (PPFh) is defined as a sterile solution of proteins composed mainly of albumin and globulin derived from human plasma. It is already reviewed under the category of biologics by the FDA where the processing, required tests, requirements and labeling are incorporated. This biologic should come...
Approved
Matched Description: … [A32512] It is already reviewed under the category of biologics by the FDA where the processing, required ... It is also stated that no more than 1% of the total protein should be gamma globulin. ... The plasma protein fraction human (PPFh) is defined as a sterile solution of proteins composed mainly …
Matched Products: … OCTAPLAS Blood Group A ... Octaplas SD Blutgruppe A zur Infusion …
Sodium Fluoride F 18 Injection is a positron emitting radiopharmaceutical, no-carrier added. It contains radioactive fluoride F 18 that is used for diagnostic purposes in conjunction with positron emission tomography (PET) imaging and is administered by intravenous injection. Its primary indication is for bone imaging. Increased deposition around joints can...
Approved
Matched Description: … emission tomography (PET) imaging and is administered by intravenous injection. ... Sodium Fluoride F 18 Injection is a positron emitting radiopharmaceutical, no-carrier added. ... in bone has been noted around fracture sites, in osteomyelitis, fibrous dysplasia, spondylitis tuberculosa …
Matched Products: … MON.NAF (18F) 250 MBQ/ML IV ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 1 ADET …
Spironolactone is a potassium-sparing diuretic. It binds to mineralocorticoid receptors and functions as aldosterone antagonists. It promotes sodium and water excretion and potassium retention. Spironolactone was originally developed purely for this ability before other pharmacodynamic properties of the drug were discovered.[A11837, A178246] It is indicated to treat several conditions, including...
Approved
Matched Iupac: … (acetylsulfanyl)-9a,11a-dimethyl-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydrospiro[cyclopenta[a] …
Matched Description: … [A178135, A261025] Spironolactone was developed in 1957, marketed in 1959, and approved by the FDA ... Spironolactone is a potassium-sparing diuretic. ... the drug were discovered. …
Matched Mixtures name: … Clindamycin 1% / Niacinamide 4% / Spironolactone 2% / Tretinoin 0.025% ... Benzoyl Peroxide 5% / Clindamycin 1% / Niacinamide 2% / Spironolactone 2% ... Benzoyl Peroxide 5% / Clindamycin 1% / Niacinamide 2% / Spironolactone 2% / Tretinoin 0.05% …
Matched Products: … ALDACTONE A ... ALDACTONE-A 25 MG TABLET, 20 ADET …
Selexipag was approved by the United States FDA on December 22, 2015 for the treatment of pulmonary arterial hypertension (PAH) to delay disease progression and reduce risk of hospitalization. PAH is a relatively rare disease with usually a poor prognosis requiring more treatment options to prolong long-term outcomes. Marketed by...
Approved
Matched Description: … Selexipag was approved by the United States FDA on December 22, 2015 for the treatment of pulmonary arterial ... -333679 (MRE-269), act as agonists of the prostacyclin receptor to increase vasodilation in the pulmonary ... circulation and decrease elevated pressure in the blood vessels supplying blood to the lungs. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Semaglutide is a glucagon-like peptide 1 (GLP-1) analog used to manage type 2 diabetes along with lifestyle changes, such as dietary restrictions and increased physical activity.[A31421,L8681] Other members of this drug class include Exenatide and Liraglutide. Semaglutide was developed by Novo Nordisk and approved by the FDA for subcutaneous injection...
Approved
Investigational
Matched Iupac: … {[(1S)-1-{[(1S,2S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-{[(1S)-4-carbamimidamido-1-[({[(1S)-4-carbamimidamido ... -1-[(carboxymethyl)carbamoyl]butyl]carbamoyl}methyl)carbamoyl]butyl]carbamoyl}-2-methylpropyl]carbamoyl ... methylpentanamido]-4-carboxybutanamido]acetamido}-4-carbamoylbutanamido]propanamido]propanamido]-5-{[(1S)-1- ... carboxypropyl]carbamoyl}pentyl]carbamoyl}methoxy)ethoxy]ethyl}carbamoyl)methoxy]ethoxy}ethyl)carbamoyl]-1- …
Matched Description: … [L34485] The use of semaglutide in weight management is also approved by Health Canada [L39347] and the ... Semaglutide was developed by Novo Nordisk and approved by the FDA for subcutaneous injection in December ... [A186053] In June 2021, semaglutide was approved by the FDA for chronic weight management in adults with …
Matched Categories: … Drugs Used in Diabetes ... Glucagon-like peptide-1 (GLP-1) analogues ... GLP-1 Agonists …
Matched Products: … Ozempic® 1.34 mg/ml (1 mg/dose) Solution for injection in pre-filled pen ... OZEMPIC 1MG/DOSE SOLUTION FOR INJECTION IN PRE-FILLED PEN 1.34MG/ML ... OZEMPIC 0.25MG, 0.5MG/DOSE SOLUTION FOR INJECTION IN PRE-FILLED PEN 1.34MG/ML …
Ranibizumab is a recombinant humanized IgG1 kappa isotype monoclonal antibody fragment directed against human vascular endothelial growth factor A (VEGF-A), which is a glycoprotein implicated in the pathophysiology of age-related macular degeneration.[A2301, L38978] Ranibizumab is used to treat various ocular disorders with abnormal growth of blood vessels, such as neovascular...
Approved
Matched Description: … BYOOVIZ, a biosimilar of LUCENTIS, was approved by Health Canada in March 2022, making it the first and ... [A246399] Ranibizumab was initially approved by the FDA in 2006 [A2301] and by the European Commission ... human vascular endothelial growth factor A (VEGF-A), which is a glycoprotein implicated in the pathophysiology …
Matched Products: … 1 Ranivisio ... LUCENTIS 10 MG/ML SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE ... LUCENTIS SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 1.65mg/0.165ml …
In the U.S., Terfenadine was superseded by fexofenadine in the 1990s due to the risk of cardiac arrhythmia caused by QT interval prolongation.
Approved
Withdrawn
Matched Synonyms: … (RS)-1-(4-tert-butylphenyl)-4-{4-[hydroxy(diphenyl)methyl]piperidin-1-yl}-butan-1-ol …
Matched Iupac: … 1-(4-tert-butylphenyl)-4-[4-(hydroxydiphenylmethyl)piperidin-1-yl]butan-1-ol …
Matched Description: … In the U.S., Terfenadine was superseded by fexofenadine in the 1990s due to the risk of cardiac arrhythmia ... caused by QT interval prolongation. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … Seldane 120mg Once-A-day Caplets ... Allergy Relief Once A Day Allergy Caplet 120mg …
Pralidoxime is an antidote to organophosphate pesticides and chemicals. Organophosphates bind to the esteratic site of acetylcholinesterase, which results initially in reversible inactivation of the enzyme. If given within 24 hours,after organophosphate exposure, pralidoxime reactivates the enzyme cholinesterase by cleaving the phosphate-ester bond formed between the organophosphate and acetylcholinesterase.
Approved
Vet approved
Matched Iupac: … 2-[(E)-(hydroxyimino)methyl]-1-methylpyridin-1-ium …
Matched Description: … Organophosphates bind to the esteratic site of acetylcholinesterase, which results initially in reversible ... inactivation of the enzyme. ... by cleaving the phosphate-ester bond formed between the organophosphate and acetylcholinesterase. …
Matched Salts cas: … 1200-55-1
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … NEOPAM 1 G ... PAM-A INJECTION 500 mg/ampoule …
Bosutinib is a 7-alkoxy-3-quinolinecarbonitrile that functions as a potent, dual SRC and ABL tyrosine kinase inhibitor indicated for chronic myelogenous leukemia (CML), specifically Philadelphia chromosome-positive (Ph+) CML. Philadelphia chromosome is a hallmark of CML due to the reciprocal translocation t(9;22)(q34;q11), resulting in a BCR-ABL fusion protein.[A6902,A261796,A261801] The first BCR-ABL inhibitor,...
Approved
Matched Synonyms: … 4-((2,4-dichloro-5-methoxyphenyl)amino)-6-methoxy-7-(3-(4-methyl-1-piperazinyl)propoxy)-3-quinolinecarbonitrile …
Matched Iupac: … 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile …
Matched Description: … [A6901,A17961] Bosutinib was first approved by the FDA in 2012 for the treatment of adult chronic, ... Philadelphia chromosome is a hallmark of CML due to the reciprocal translocation t(9;22)(q34;q11), resulting ... [L48436] On September 26, 2023, bosutinib was also approved by the FDA for the treatment of pediatric …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Cetylpyridinium is a quaternary ammonium with broad-spectrum antiseptic properties. Its salt form, cetylpyridinium chloride, is typically found as an active ingredient in mouthwashes, toothpastes, lozenges, throat sprays, breath sprays, and nasal sprays. In these products, it generally mediates an antiseptic activity and protective action against dental plaque and reducing gingivitis.
Approved
Matched Synonyms: … 1-hexadecylpyridinium …
Matched Iupac: … 1-hexadecylpyridin-1-ium …
Matched Description: … Cetylpyridinium is a quaternary ammonium with broad-spectrum antiseptic properties. ... In these products, it generally mediates an antiseptic activity and protective action against dental ... Its salt form, cetylpyridinium chloride, is typically found as an active ingredient in mouthwashes, toothpastes …
Matched Mixtures name: … Kank-A ... MEBUCAIN 2 MG/1 MG NANELI PASTIL (20 ADET) …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Heterocyclic Compounds, 1-Ring …
Matched Products: … Colgate Total 12Hr Pro-Shield Peppermint Blast ... Colgate Total Advanced Pro-Shield Peppermint Blast
Ganirelix is a synthetic decapeptide and a competitive gonadotropin-releasing hormone (GnRH) antagonist. Derived from endogenous GnRH, ganirelix has amino acid substitutions. Ganirelix is indicated for controlled ovarian hyperstimulation in assisted reproduction techniques. The first case of pregnancy achieved after the use of ganirelix in an assisted reproduction program was reported...
Approved
Matched Iupac: … (2S)-2-{[(1R)-1-carbamoylethyl]carbamoyl}pyrrolidin-1-yl]-1-oxohexan-2-yl]carbamoyl}-3-methylbutyl]-2 ... (2R)-6-{[bis(ethylamino)methylidene]amino}-N-[(1S)-1-{[(2S)-6-{[bis(ethylamino)methylidene]amino}-1-[ …
Matched Description: … [L43045] The first case of pregnancy achieved after the use of ganirelix in an assisted reproduction ... [A252195] Ganirelix was first approved by the FDA on July 29, 1999.[L43070] ... Ganirelix is a synthetic decapeptide and a competitive gonadotropin-releasing hormone (GnRH) antagonist …
Matched Products: … ORGALUTRAN 0,25 MG/0,5 ML ENJEKSİYONLUK ÇÖZELTİ, 1 ADET ... ORGALUTRAN 0,25 MG/0.5 ML ENJEKSİYONLUK ÇÖZELTİ, 1 ADET ... Ganirelix Astro 0,25 mg/0,5 ml Injektionslösung in einer Fertigspritze …
Conivaptan is a non-peptide inhibitor of antidiuretic hormone (vasopressin). It was approved in 2004 for hyponatremia (low blood sodium levels) caused by syndrome of inappropriate antidiuretic hormone (SIADH). Conivaptan inhibits both isotypes of the vasopressin receptor (V1a and V2).
Approved
Investigational
Matched Synonyms: … 4'-((4,5-dihydro-2-methylimidazo(4,5-d)(1)benzazepin-6(1H)-yl)carbonyl)-2-biphenylcarboxanilide …
Matched Iupac: … N-(4-{4-methyl-3,5,9-triazatricyclo[8.4.0.0^{2,6}]tetradeca-1(14),2(6),3,10,12-pentaene-9-carbonyl}phenyl …
Matched Description: … It was approved in 2004 for hyponatremia (low blood sodium levels) caused by syndrome of inappropriate ... Conivaptan is a non-peptide inhibitor of antidiuretic hormone (vasopressin). ... Conivaptan inhibits both isotypes of the vasopressin receptor (V1a and V2). …
Matched Categories: … Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Products: … Vaprisol Dextrose In Plastic Container …
Tocilizumab is a recombinant humanized monoclonal antibody IL-6 receptor inhibitor used to treat inflammatory and autoimmune conditions. It was first described in the literature in 2003 when Chugai, a subsidiary of Roche began developing IL-6 inhibiting monoclonal antibodies. Tocilizumab was granted FDA approval on 8 January 2010 to treat a...
Approved
Matched Description: … [L12789] It was first described in the literature in 2003 when Chugai, a subsidiary of Roche began developing ... [L44483] Tocilizumab-bavi, a biosimilar drug, was approved by the FDA in September 2023.[L48385] ... [L40164] Subsequently, it was granted approval by Health Canada and the FDA in October [L43697] and December …
Matched Products: … ACTEMRA (162 MG SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE) ... ACTEMRA 162MG/0.9ML SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE ... ACTEMRA 200 MG/10 ML IV INFUZYONLUK COZELTI KONSANTRESI İÇEREN FLAKON, 1 ADET …
Novartis' brand name Zelnorm (tegaserod) had originally received approval from the US FDA in 2002 for the treatment of irritable bowel syndrome with constipation (IBS-C).[L5918,F4229] It was, however, voluntarily withdrawn from widespread use in the US market in 2007 after concerns arose over the possibility that tegaserod could potentially cause...
Approved
Investigational
Withdrawn
Matched Synonyms: … 1-(((5-Methoxyindol-3-yl)methylene)amino)-3-pentylguanidine …
Matched Description: … in female patients less than 65 years of age and whom are considered to be at a lower risk of a cardiovascular ... [L5918,F4229] Zelnorm (tegaserod) by Sloan Pharma subsequently gained re-approval in April of 2019. ... mechanism of action of acting on serotonin-4 (5-HT(4)) receptors in smooth muscle cells and in the gastrointestinal …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Displaying drugs 226 - 250 of 14564 in total