Displaying drugs 2626 - 2650 of 9574 in total
Omidenepag isopropyl
Omidenepag isopropyl is a topical ocular hypotensive agent used to reduce intraocular pressure (IOP) in patients with glaucoma and ocular hypertension. Omidenepag isopropyl is quickly metabolized to its active metabolite, omidenepag, a molecule with high selectivity and agonistic activity towards the prostaglandin E2 (EP2) receptor.[A253263,A253268] Prostanoid FP receptor agonists (FP...
Approved
Investigational
Matched Description: … [A253268] In September 2022, the FDA approved the use of omidenepag isopropyl.[L43503] ... The use of an EP2 receptor agonist such as omidenepag represents an alternative in these scenarios. ... [A253263,A253268] Prostanoid FP receptor agonists (FP agonists), such as [latanoprost], are part of the …
Matched Categories: … combinations of sulfonamides …
Matched Categories: … combinations of sulfonamides …
Tocilizumab
Tocilizumab is a recombinant humanized monoclonal antibody IL-6 receptor inhibitor used to treat inflammatory and autoimmune conditions. It was first described in the literature in 2003 when Chugai, a subsidiary of Roche began developing IL-6 inhibiting monoclonal antibodies. Tocilizumab was granted FDA approval on 8 January 2010 to treat a...
Approved
Matched Description: … autoimmune disorders, such as different types of arthritis and cytokine release syndrome. ... [A193281] Tocilizumab was granted FDA approval on 8 January 2010 to treat a number of inflammatory and ... [L12789] It was first described in the literature in 2003 when Chugai, a subsidiary of Roche began developing …
Glymidine
Glycodiazine is used with diet to lower blood glucose by increasing the secretion of insulin from pancreas and increasing the sensitivity of peripheral tissues to insulin. The mechanism of action of glycodiazine in lowering blood glucose appears to be dependent on stimulating the release of insulin from functioning pancreatic beta...
Approved
Investigational
Matched Description: … The mechanism of action of glycodiazine in lowering blood glucose appears to be dependent on stimulating ... the release of insulin from functioning pancreatic beta cells, and increasing sensitivity of peripheral ... and increasing the sensitivity of peripheral tissues to insulin. …
Matched Categories: … combinations of sulfonamides …
Matched Categories: … combinations of sulfonamides …
Butoconazole
Butoconazole is an imidazole antifungal used in gynecology.
Approved
Matched Categories: … combinations of imidazole derivatives …
Sodium cellulose phosphate
Sodium cellulose phosphate is used to treat hypercalcemia and hypercalciuria. It has been used to prevent kidney stones. This compound is an ion-exchange resin that can not be absorbed by the body. However, it can be used to restore normal intestinal calcium absorption.
Approved
Matched Categories: … Drugs for Treatment of Hypercalcemia …
Interferon alfa-2a
Interferon a (human leukocyte protein moiety reduced). A type I interferon consisting of 165 amino acid residues with lysine in position 23. This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes. It is used extensively as an antiviral or antineoplastic agent. An oral form is...
Approved
Investigational
Matched Description: … A type I interferon consisting of 165 amino acid residues with lysine in position 23. …
Tiludronic acid
Tiludronate, or (4-chlorophenyl)thio-methylene-1,1-bisphosphonate, is a first generation bisphosphonate similar to etidronic acid and clodronic acid.[A1923,A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and decalcification. Tiludronic acid was first described in the literature in 1988 as a potential treatment for Paget's disease of bone....
Approved
Investigational
Vet approved
Matched Description: … [A1923,A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification ... Tiludronic acid was first described in the literature in 1988 as a potential treatment for Paget's disease of …
Matched Categories: … Drugs for Treatment of Bone Diseases …
Matched Categories: … Drugs for Treatment of Bone Diseases …
Diclofenamide
A carbonic anhydrase inhibitor that is used in the treatment of glaucoma.
Approved
Investigational
Matched Description: … A carbonic anhydrase inhibitor that is used in the treatment of glaucoma. …
Matched Categories: … combinations of sulfonamides …
Matched Categories: … combinations of sulfonamides …
Mazindol
Mazindol is a tricyclic anorexigenic agent that is unrelated to and less toxic than amphetamine, but with some similar side effects. It inhibits uptake of catecholamines and blocks the binding of cocaine to the dopamine uptake transporter. Mazindol is only approved in the United States for the treatment of Duchenne...
Approved
Investigational
Matched Description: … It inhibits uptake of catecholamines and blocks the binding of cocaine to the dopamine uptake transporter ... is not marketed or available in the United States for use in the treatment of obesity. ... Mazindol is only approved in the United States for the treatment of Duchenne muscular dystrophy, and …
Matched Categories: … Combined Inhibitors of Serotonin/Norepinephrine Reuptake ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Categories: … Combined Inhibitors of Serotonin/Norepinephrine Reuptake ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Lymecycline
Lymecycline is a broad-spectrum second-generation tetracycline antibiotic used for the treatment of acne and other susceptible bacterial infections.[L13880,L13883] It has been proven a cost-effective alternative to treatment with minocycline with comparable safety and efficacy. Lymecycline was initially discovered in 1961. It is marketed by Galderma and used in the UK...
Approved
Investigational
Matched Description: … Lymecycline is a broad-spectrum second-generation tetracycline antibiotic used for the treatment of acne …
Matched Categories: … combinations of tetracyclines …
Matched Categories: … combinations of tetracyclines …
Methohexital
An intravenous anesthetic with a short duration of action that may be used for induction of anesthesia.
Approved
Matched Description: … An intravenous anesthetic with a short duration of action that may be used for induction of anesthesia …
Matched Categories: … combinations of barbiturates …
Matched Categories: … combinations of barbiturates …
Propyliodone
Radiopaque medium usually in oil; used in bronchography.
Approved
Matched Categories: … Diagnostic Uses of Chemicals …
Vosoritide
Achondroplasia is an autosomal dominant genetic disease and the most common cause of dwarfism in humans. It results from a gain-of-function missense mutation in FGFR3 that results in a dramatic suppression of bone growth, both in volume and in length.[A242273,A242277] Treatment for achondroplasia includes both surgical and pharmacological interventions, the...
Approved
Investigational
Matched Description: … suppression of bone growth, both in volume and in length. ... Achondroplasia is an autosomal dominant genetic disease and the most common cause of dwarfism in humans ... [A242277] It results from a gain-of-function missense mutation in _FGFR3_ that results in a dramatic …
Matched Categories: … Drugs for Treatment of Bone Diseases …
Matched Categories: … Drugs for Treatment of Bone Diseases …
Lutetium Lu 177 dotatate
A 177Lu-labeled somatostatin analog peptide, Lutetium Lu 177 dotatate belongs to an emerging form of treatments called Peptide Receptor Radionuclide Therapy (PRRT), which involves targeting tumours with molecules carrying radioactive particles that bind to specific receptors expressed by the tumour. Lutetium Lu 177 dotatate may also be referred to as...
Approved
Investigational
Matched Description: … The presence of a radioligand allows monitoring of treatment response post therapy and prior to next ... fraction of the dose delivery which may be clinically beneficial in estimating the intensity of lesion ... A 177Lu-labeled somatostatin analog peptide, Lutetium Lu 177 dotatate belongs to an emerging form of …
Matched Categories: … Diagnostic Uses of Chemicals …
Matched Categories: … Diagnostic Uses of Chemicals …
Zinc ascorbate
Approved
Nutraceutical
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Hetacillin
Hetacillin is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually gram-positive, organisms. The name "penicillin" can either refer to several variants of penicillin available, or to the group of antibiotics derived from the penicillins. Hetacillin has in vitro activity against gram-positive and gram-negative...
Approved
Vet approved
Withdrawn
Matched Description: … The name "penicillin" can either refer to several variants of penicillin available, or to the group of ... The bactericidal activity of Hetacillin results from the inhibition of cell wall synthesis and is mediated ... Hetacillin is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused …
Matched Categories: … combinations of penicillins …
Matched Categories: … combinations of penicillins …
Fluoxymesterone
An anabolic steroid that has been used in the treatment of male hypogonadism, delayed puberty in males, and in the treatment of breast neoplasms in women.
Approved
Illicit
Matched Description: … , and in the treatment of breast neoplasms in women. ... An anabolic steroid that has been used in the treatment of male hypogonadism, delayed puberty in males …
Matched Categories: … Sex Hormones and Modulators of the Genital System …
Matched Categories: … Sex Hormones and Modulators of the Genital System …
Iopanoic acid
Iopanoic acid contains iodine and is useful as a contrast medium in cholecystography.
Approved
Withdrawn
Matched Categories: … Diagnostic Uses of Chemicals …
Fludeoxyglucose (18F)
Fludeoxyglucose F 18 Injection is a positron emitting radiopharmaceutical containing no-carrier added radioactive 2-deoxy-2-[18F]fluoro-D-g1ucose, which is used for diagnostic purposes in conjunction with Positron Emission Tomography (PET). It is administered by intravenous injection.
Approved
Investigational
Matched Categories: … Diagnostic Uses of Chemicals …
Sultamicillin
Sultamicillin has been used in trials studying the prevention and treatment of Ventilator Associated Pneumonia and Chronic Obstructive Pulmonary Disease (COPD).
Approved
Investigational
Matched Description: … Sultamicillin has been used in trials studying the prevention and treatment of Ventilator Associated …
Matched Categories: … combinations of penicillins …
Matched Categories: … combinations of penicillins …
Metaxalone
Metaxalone is a moderate to strong muscle relaxant used in the symptomatic treatment of musculoskeletal pain caused by strains, sprains, and other musculoskeletal conditions. It is marketed by King Pharmaceuticals under the brand name Skelaxin®. Its main mechanism of action is thought to involve general central nervous system depression. Metaxalone...
Approved
Matched Description: … Metaxalone is a moderate to strong muscle relaxant used in the symptomatic treatment of musculoskeletal ... Its main mechanism of action is thought to involve general central nervous system depression. …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Bromotheophylline
Bromotheophylline is the active moiety of pamabrom, a mixture of 2-amino-2-methyl-propanol and bromotheophylline. From this mixture, bromotheophylline acts as a weak diuretic that has been used along with some analgesics to relieve the symptoms of premenstrual syndrome. Bromotheophylline is categorized on the FDA as a drug substance with an inactive...
Approved
Matched Description: … Bromotheophylline is the active moiety of pamabrom, a mixture of 2-amino-2-methyl-propanol and bromotheophylline ... bromotheophylline acts as a weak diuretic that has been used along with some analgesics to relieve the symptoms of …
Matched Categories: … combinations of xanthines …
Matched Categories: … combinations of xanthines …
Econazole
A broad spectrum antimycotic with some action against Gram positive bacteria. It is used topically in dermatomycoses also orally and parenterally.
Approved
Matched Categories: … combinations of imidazole derivatives ... Metabolic Side Effects of Drugs and Substances …
Displaying drugs 2626 - 2650 of 9574 in total