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Displaying drugs 251 - 275 of 11034 in total
Acetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment of acetaminophen overdose.[L31378,L31383,L31388,L31478] Acetylcysteine has also been studied for a wide variety of off-label indications with mixed results.[A228158,A228163,A228168] Acetylcysteine was granted FDA approval on 14 September 1963.
Approved
Investigational
Matched Mixtures name: … ASCOVIT 900/300MG SAŞE, 20 SAŞE ... ASCOVIT 1200/400MG SAŞE, 20 SAŞE ... MUCOFIX 600/200 MG EFERVESAN, 20 ADET …
Matched Products: … XPECTO 300 MG SAŞE, 20 ADET ... ASIST 200 MG KAPSUL, 20 ADET ... ASIST 1200 MG TOZ ICEREN 20 SASE …
Ketoconazole is an imidazole antifungal agent used in the prevention and treatment of a variety of fungal infections.[FDA Label] It functions by preventing the synthesis of ergosterol, the fungal equivalent of cholesterol, thereby increasing membrane fluidity and preventing growth of the fungus.[A181802,T116] Ketoconazole was first approved in an oral formulation...
Approved
Investigational
Matched Iupac: … -1-yl]ethan-1-one ... 1-[4-(4-{[2-(2,4-dichlorophenyl)-2-[(1H-imidazol-1-yl)methyl]-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin …
Matched Mixtures name: … Hydrocortisone 2.5% / Iodoquinol 1% / Ketoconazole 2% …
Matched Products: … NIZORAL SHAMPOO 20 mg/g ... PRISTINE SHAMPOO 20 mg/g ... FORMYCO TOPICAL CREAM 20 mg/g …
Metastatic triple-negative breast cancer (mTNBC) is an aggressive form of breast cancer with limited treatment options involving cytotoxic chemotherapy agents. Targeted chemotherapy through the application of antibody-conjugated agents (ADCs) is a recent advance in cancer treatment. One such ADC is sacituzumab govitecan, which combines a humanized anti-trophoblast cell-surface antigen 2...
Approved
Investigational
Matched Description: … [L13002, A193674] Sacituzumab govitecan was granted FDA approval on April 22nd, 2020 and is marketed ... [A193653] In November 2021 and July 20 2023, sacituzumab govitecan was also approved by the European …
Matched Products: … TRODELVY 200 MG İNFÜZYONLUK ÇÖZELTİ KONSANTRESİ İÇİN TOZ, 1 ADET …
A sympathomimetic agent with properties similar to dextroamphetamine. It is used in the treatment of obesity. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1222)
Approved
Illicit
Matched Synonyms: … N-methyl-1-phenyl-N-(phenylmethyl)propan-2-amine …
Matched Iupac: … benzyl(methyl)[(2S)-1-phenylpropan-2-yl]amine …
Matched Categories: … Adrenergic alpha-1 Receptor Agonists …
Oxycodone is a semisynthetic opioid analgesic derived from thebaine in Germany in 1917. It is currently indicated as an immediate release product for moderate to severe pain and as an extended release product for chronic moderate to severe pain requiring continuous opioid analgesics for an extended period.[Label] The first oxycodone...
Approved
Illicit
Investigational
Matched Mixtures name: … OXYCODON COMP 1A 20/10MG ... OXYCODON COMP 1A 20/10MG ... OXYCODON COMP 1A 20/10MG …
Matched Products: … Oxygerolan 1 mg/ml-Lösung zum Einnehmen ... Supeudol 20 ... OXIDONA® 20 MG …
Thiosulfuric acid is available in its salt forms sodium thiosulfate and sodium thiosulfate pentahydrate. Sodium thiosulfate is part of the World Health Organization’s list of essential medicines, and it has a variety of industrial uses, including food preservative, water de-chlorinator and paper pulp bleaching agent. Sodium thiosulfate is rapidly degraded...
Approved
Investigational
Matched Iupac: … dihydroxy-1lambda6-disulfen-1-one …
Matched Products: … TIOSULFATO DE SODIO 20% …
A centrally acting central muscle relaxant with sedative properties. It is claimed to inhibit muscle spasm by exerting an effect primarily at the level of the spinal cord and subcortical areas of the brain. (From Martindale, The Extra Pharmacopoea, 30th ed, p1202)
Approved
Matched Mixtures name: … MEPADOL TABLET, 20 ADET ... MUSKAZON TABLET, 20 ADET ... PARAFON 250MG/300MG TABLET, 20 ADET …
Matched Products: … PARAFLEX 250 MG TABLET, 20 ADET ... PARAFLEX FORTE TABLET 500 MG, 20 ADET …
Articaine is a dental local anesthetic. Articaine is widely used around the world and is the most popular local anesthetic in many European countries.
Approved
Matched Mixtures name: … FULLCAIN AMPUL , 20 AMPUL ... FULLCAIN FORT AMPUL , 20 AMPUL ... ULTRACAIN DS 40 MG/Ml+6 MCG/ML ENJEKSİYONLUK ÇÖZELTİ, 20 AMPUL …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Citalopram is an antidepressant belonging to the class of selective serotonin-reuptake inhibitors (SSRIs) widely used to treat the symptoms of depression. It is a racemic bicyclic phthalate derivate and is the only compound with a tertiary amine and 2 nitrogen-containing metabolites among all SSRIs.[A261316,A14720] Citalopram enhances serotonergic transmission through the...
Approved
Matched Iupac: … 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile …
Matched Products: … Celexa 20 mg ... Citalopram-20 ... CITALOPRAM-NEURAX 20 MG …
Avelumab is a human IgG1 lambda monoclonal antibody that binds programmed cell death ligand-1 (PD-L1) to block its interaction with its receptors found on T cells and antigen-presenting cells. Avelumab was first approved by the FDA on March 23, 2017. On September 18 and December 18 of the same year,...
Approved
Investigational
Matched Description: … Avelumab is a human IgG1 lambda monoclonal antibody that binds programmed cell death ligand-1 (PD-L1) …
Matched Categories: … PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitors ... PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitors ... Programmed Death Ligand-1 Blocker ... Programmed Death Ligand-1 Antagonists ... Programmed Death Ligand-1-directed Antibody Interactions …
Matched Products: … BAVENCIO 200 MG/10 ML IV İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 FLAKON …
Ceftriaxone is a broad-spectrum third-generation cephalosporin antibiotic. It has a very long half-life compared to other cephalosporins and is high penetrable into the meninges , eyes , and inner ear . Ceftriaxone has broader and stronger gram-negative coverage then first or second-generation cephalosporins, but worse activity against methicillin-susceptible S.aureus. Ceftriaxone...
Approved
Matched Iupac: … acetamido]-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-8-oxo-5-thia-1- …
Matched Mixtures name: … SEFABEL 1 G I.M. ENJEKSIYONLUK ÇÖZELTI HAZIRLAMAK IÇIN KURU TOZ IÇEREN FLAKON ,1 ADET ... เซ็บทรี ชนิดฉีดเข้ากล้าม (1 กรัม) ... Hovid Ceftriaxone 1g with Lidocaine 1% …
Matched Products: … DESEFIN 2 G IV ENJ COZELTI HAZIRLAMAK IÇIN TOZ IÇEREN FLAKON,FLAKON, 1 ADET, 20 ML FLAKON, 1 ADET ... FORSEF 1 G IM ENJEKTABL TOZ İÇEREN FLAKON, 1 FLAKON + 1 AMPUL ... FORSEF 1 G IV ENJEKTABL TOZ İÇEREN FLAKON, 1 FLAKON + 1 AMPUL …
Valdecoxib was removed from the Canadian, U.S., and E.U. markets in 2005 due to concerns about a possible increased risk of heart attack and stroke.
Approved
Investigational
Withdrawn
Matched Iupac: … 4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)benzene-1-sulfonamide …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … PARALGEN ® 20 TABLETAS ... BEXTRA®20 MG TABLETAS RECUBIERTAS ... VALDYNE 20 MG TABLETAS RECUBIERTAS …
Bacteria possess a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which is synthesized and remodelled through the action of a family of enzymes known as "penicillin-binding proteins" (PBPs). β-lactam antibiotics, including cephalosporins, are PBP inhibitors that, through inhibition of essential PBPs, result in impaired cell wall homeostasis,...
Approved
Investigational
Matched Iupac: … 7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(carboxymethoxy)imino]acetamido]-3-ethenyl-8-oxo-5-thia-1- …
Matched Mixtures name: … INNOCEF PLUS 200/125 MG SAŞE, 20 ADET ... INNOCEF PLUS 400/125 MG SAŞE, 20 ADET ... INNOCEF PLUS 100/62.5 MG SASE, 20 ADET …
Matched Products: … INNOCEF 100 MG SAŞE, 20 ADET ... INNOCEF 200 MG SAŞE, 20 ADET ... INNOCEF 400 MG SAŞE, 20 ADET …
A white crystal or crystalline powder used as an electrolyte replenisher, in the treatment of hypokalemia, in buffer solutions, and in fertilizers and explosives. The FDA withdrew its approval for the use of all solid oral dosage form drug products containing potassium chloride that supply 100 mg or more of...
Approved
Withdrawn
Matched Mixtures name: … MULTIELECTROLITOS TIPO 1 ... AMINOMIX 1 NOVUM 1500 ML ... AMINOMIX 1 INTRAVENÖZ İNZFÜZYON, 1000 ML …
Matched Products: … Kaochlor-20 ... Kcl Solution A 20% ... CLORURO DE POTASIO 20 MEQ/10 ML …
Histrelin is a gonadotropin-releasing hormone (GnRH) agonist that acts as a potent inhibitor of gonadotropin when administered as an implant delivering continuous therapeutic doses. This drug is a synthetic analog of naturally occurring GnRH with a higher potency. Histrelin implants are non-biodegradable, diffusion-controlled, hydrogel polymer reservoirs containing histrelin acetate that...
Approved
Withdrawn
Matched Synonyms: … 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-1-benzyl-D-histidyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide …
Matched Iupac: … (2S)-1-[(2S)-2-[(2S)-2-[(2R)-3-(1-benzyl-1H-imidazol-4-yl)-2-[(2S)-2-[(2S)-3-hydroxy-2-[(2S)-2-[(2S)- …
A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985)....
Approved
Investigational
Matched Iupac: … 1,3-bis(2-chloroethyl)-1-nitrosourea …
Matched Products: … BİCNU 100 MG ENJEKSİYONLUK ÇÖZELTİ İÇİN TOZ İÇEREN FLAKON VE ÇÖZÜCÜSÜ, 1 ADET TOZ FLAKON, 1 ADET ÇÖZÜCÜ …
Ruxolitinib, formerly known as INCB018424 or INC424, is an anticancer drug and a Janus kinase (JAK) inhibitor. It is a potent and selective inhibitor of JAK1 and JAK2, which are tyrosine kinases involved in cytokine signalling and hematopoiesis. Myeloproliferative neoplasms, such as myelofibrosis and polycythemia vera, are often characterized by...
Approved
Matched Iupac: … (3R)-3-cyclopentyl-3-(4-{7H-pyrrolo[2,3-d]pyrimidin-4-yl}-1H-pyrazol-1-yl)propanenitrile …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … JAKAVI 20 MG (TABLETS) ... JAKAVI 20 MG TABLET, 168 TABLET ... JAKAVİ 20 MG TABLET, 14 ADET …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Mixtures name: … Flulaval Quadrivalent 2020/2021 …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Mixtures name: … Flulaval Quadrivalent 2020/2021 …
Nifedipine, or BAY a 1040, is a first generation dihydropyridine L-type calcium channel blocker, similar to nicardipine.[A190210,A190273,A175390,L11383] Nifedipine was developed by Bayer and first described in the literature, along with other dihydropyridines, in 1972.[A175390,A190276] Since nifedipine's development, second and third generation dihydropyridines have been developed with slower onsets and longer...
Approved
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … NIFEDIPIN T 20 STADA RETARD TABLET 20 mg ... ADALAT CR 20 ... Adalat Pa 20
Ginkgo biloba extract contains a group of terpene lactones (notably, ginkgolides and diterpenes) and ginkgo flavone glycosides (notably, ginkgetin, bilobetin, and sciadopitysin) that have antioxidant and vasoactive properties. Most of the studies that investigate the effect of ginkgo biloba use the standardized extract of Ginkgo biloba (EGb) 761 (EGb761), which...
Approved
Investigational
Nutraceutical
Matched Mixtures name: … DOMINGO 10/20/80 MG EFERVESAN TABLET, 30 ADET ... DOMINGO 10/20/80 MG EFERVESAN TABLET, 90 ADET ... DOMINGO 5/20/80 MG EFERVESAN TABLET, 30 ADET …
Matched Products: … BILOKAN FORTE DAMLA, 20 ML ... SEREMAKS FORT FİLM TABLET, 20 ADET ... GINGOBIL 40 MG FİLM TABLET, 20 ADET …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Mixtures name: … Flulaval Quadrivalent 2020/2021 …
Repaglinide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It belongs to the meglitinide class of short-acting insulin secretagogues, which act by binding to β cells of the pancreas to stimulate insulin release. Repaglinide induces an early insulin response to meals decreasing postprandial blood...
Approved
Investigational
Matched Iupac: … 2-ethoxy-4-({[(1S)-3-methyl-1-[2-(piperidin-1-yl)phenyl]butyl]carbamoyl}methyl)benzoic acid …
Matched Mixtures name: … REPAMEF 1/1000 MG EFERVESAN TABLET, 30 ADET ... REPAMEF 1/500 MG EFERVESAN TABLET, 30 ADET ... REPAMEF 1/1000 MG EFERVESAN TABLET, 90 ADET …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … NOVONORM TABLET 1 mg ... REPLIC 1 MG TABLET, 30 ADET ... NOVADE 1 MG TABLET, 90 ADET …
Burosumab (KRN23) is an entirely human monoclonal IgG1 antibody that binds excess fibroblast growth factor 23 (FGF23) and has been successfully tested in clinical trials in children with X-linked hypophosphatemic rickets . The U.S. Food and Drug Administration approved Crysvita (burosumab) in April 2018. This is the first drug approved...
Approved
Investigational
Matched Description: … This is the first drug approved to treat adults and children ages 1 year and older with X-linked hypophosphatemia …
Matched Products: … CRYSVITA 20 MG SOLUTION FOR INJECTION ... CRYSVITA® SOLUCIÓN PARA INYECCIÓN 20 MG/ML ... CRYSVITA® SOLUTION FOR INJECTION 20 MG/ML …
Difluprednate is a topical corticosteroid indicated for the treatment of infammation and pain associated with ocular surgery. It is a butyrate ester of 6(α), 9(α)-difluoro prednisolone acetate. Difluprednate is abbreviated DFBA, or difluoroprednisolone butyrate acetate. It is indicated for treatment of endogenous anterior uveiti.
Approved
Matched Iupac: … -1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl butanoate ... (1R,3aS,3bS,5S,9aS,9bR,10S,11aS)-1-[2-(acetyloxy)acetyl]-5,9b-difluoro-10-hydroxy-9a,11a-dimethyl-7-oxo …
Matched Products: … DİFLUNAT POMAT, 20 G ... EPITOPIC POMAT %0,05, 20 G …
Displaying drugs 251 - 275 of 11034 in total