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Displaying drugs 251 - 275 of 9510 in total

Amylmetacresol

Amylmetacresol is an antiseptic available in Canada over-the-counter in a number of lozenges for the treatment of sore throat and minor mouth infections , . Amylmetacresol is often combined with dichlorobenzyl alcohol and menthol in the commonly used sore throat lozenges, known as Strepsils . The acute sore throat (pharyngitis)...
Approved
Matched Description: … treatment of sore throat and minor mouth infections [L2570], [L2571]. ... symptoms, and are increasingly important in the management of this condition [A32787]. ... Amylmetacresol is an antiseptic available in Canada over-the-counter in a number of lozenges for the …
Matched Mixtures name: … ซีพาคอล(R) อาร์เอ็กซ์ ... ซีพาคอล(R) อาร์เอ็กซ์ …

Benzatropine

Benztropine, with the chemical formula 3alpha-diphenylmethoxytropane, is a tropane-based dopamine inhibitor used for the symptomatic treatment of Parkinson's disease. It is a combination molecule between a tropane ring, similar to cocaine, and a diphenyl ether from the dialkylpiperazines determined to be a dopamine uptake inhibitor since 1970. The generation of...
Approved
Matched Description: … of a chlorine substituent in the para position in one of the phenyl rings produces an increased potency ... 3alpha-diphenylmethoxytropane, is a tropane-based dopamine inhibitor used for the symptomatic treatment of ... for dopamine uptake inhibition as well as a decreased inhibition of serotonin and norepinephrine. …
Matched Categories: … Ethers of Tropine or Tropine Derivatives …

Pentobarbital

A short-acting barbiturate that is effective as a sedative and hypnotic (but not as an anti-anxiety) agent and is usually given orally. It is prescribed more frequently for sleep induction than for sedation but, like similar agents, may lose its effectiveness by the second week of continued administration. (From AMA...
Approved
Investigational
Vet approved
Matched Description: … induction than for sedation but, like similar agents, may lose its effectiveness by the second week of …
Matched Categories: … combinations of barbiturates …

Loxapine

An antipsychotic agent used in schizophrenia. [PubChem]
Approved
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Metolazone

A quinazoline-sulfonamide that is considered a thiazide-like diuretic which is long-acting so useful in chronic renal failure. It also tends to lower blood pressure and increase potassium loss.
Approved
Matched Categories: … combinations of sulfonamides …

Linezolid

Linezolid is a synthetic antibiotic which is used for the treatment of infections caused by aerobic Gram-positive bacteria. Its effects are bacteriostatic against both enterococci and staphylococci and bactericidal against most isolates of streptococci. Linezolid exerts its antibacterial activity by inhibiting the initiation of bacterial protein synthesis - more specifically,...
Approved
Investigational
Matched Description: … are bacteriostatic against both enterococci and staphylococci and bactericidal against most isolates of ... [L32965] Linezolid exerts its antibacterial activity by inhibiting the initiation of bacterial protein ... synthesis - more specifically, it binds to the 23S ribosomal RNA of the 50S subunit[A11227,A199050] …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Minaprine

Minaprine is a psychotropic drug which has proved to be effective in the treatment of various depressive states. Like most antidepressants minaprine antagonizes behavioral despair. Minaprine is an amino-phenylpyridazine antidepressant reported to be relatively free of cardiotoxicity, drowsiness, and weight gain.
Approved
Matched Description: … Minaprine is a psychotropic drug which has proved to be effective in the treatment of various depressive ... Minaprine is an amino-phenylpyridazine antidepressant reported to be relatively free of cardiotoxicity …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Opium

Opium is the first substance of the diverse group of the opiates. It has been known for a long time, and the first evidence of a poppy culture dates from 5 thousand years by the Sumerians. During the years, opium was used as a sedative and hypnotic, but it was...
Approved
Illicit
Matched Description: … Opium is the first substance of the diverse group of the opiates. ... harmful effects of opium. ... in the category of isoquinolines. …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Rubidium Rb-82

Rubidium chloride Rb-82 injection is a sterile nonpyrogenic solutions of rubidium Rb 82 chloride. It is indicated for Positron Emission Tomography (PET) imaging of the myocardium under rest or pharmacologic stress conditions to evaluate regional myocardial perfusion in adult patients with suspected or existing coronary artery disease.
Approved
Investigational
Matched Description: … Rubidium chloride Rb-82 injection is a sterile nonpyrogenic solutions of rubidium Rb 82 chloride. ... It is indicated for Positron Emission Tomography (PET) imaging of the myocardium under rest or pharmacologic …

Vitamin A

Retinol and derivatives of retinol that play an essential role in metabolic functioning of the retina, the growth of and differentiation of epithelial tissue, the growth of bone, reproduction, and the immune response. Dietary vitamin A is derived from a variety of carotenoids found in plants. It is enriched in...
Approved
Nutraceutical
Vet approved
Matched Description: … , the growth of and differentiation of epithelial tissue, the growth of bone, reproduction, and the immune ... Retinol and derivatives of retinol that play an essential role in metabolic functioning of the retina ... Dietary vitamin A is derived from a variety of carotenoids found in plants. …
Matched Mixtures name: … Formula R Tab …

Oseltamivir

Oseltamivir (marketed as the product TamifluⓇ), is an antiviral neuraminidase inhibitor used for the treatment and prophylaxis of infection with influenza viruses A (including pandemic H1N1) and B. Oseltamivir exerts its antiviral activity by inhibiting the activity of the viral neuraminidase enzyme found on the surface of the virus, which...
Approved
Matched Description: … The clinical benefit of use of oseltamivir is greatest when administered within 48 hours of the onset ... use of oseltamivir. ... [L7264] The benefits of oseltamivir use are controversial; a 2014 Cochrane Review of the evidence …
Matched Products: … TAZAMIR(R) CAPSULA 75 MG …

Griseofulvin

An antifungal antibiotic. Griseofulvin may be given by mouth in the treatment of tinea infections.
Approved
Investigational
Vet approved
Matched Iupac: … (2S,6'R)-7-chloro-2',4,6-trimethoxy-6'-methyl-3H-spiro[1-benzofuran-2,1'-cyclohexan]-2'-ene-3,4'-dione …
Matched Description: … Griseofulvin may be given by mouth in the treatment of tinea infections. …

Bisacodyl

Bisacodyl, a diphenylmethane derivative, is a commonly used over the counter stimulant laxative for occasional constipation.[A233300,L13362] Both bisacodyl and picosulfate are metabolized to the same active metabolite bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM).[A233290,A233300,A207700] Bisacodyl was patented on 25 September 1956 but has been used as a laxative since 1952.
Approved
Matched Products: … ERPLUS(R) GRAGEAS ... BET-R-PREP Bisacodyl …

Fluvoxamine

Fluvoxamine is an antidepressant which functions pharmacologically as a selective serotonin reuptake inhibitor. Though it is in the same class as other SSRI drugs, it is most often used to treat obsessive-compulsive disorder. Fluvoxamine has been in use in clinical practice since 1983 and has a clinical trial database comprised...
Approved
Investigational
Matched Description: … As of the end of 1995, more than 10 million patients worldwide have been treated with fluvoxamine. ... Fluvoxamine has been in use in clinical practice since 1983 and has a clinical trial database comprised of …
Matched Categories: … Metabolic Side Effects of Drugs and Substances ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Trimipramine

Tricyclic antidepressant similar to imipramine, but with more antihistaminic and sedative properties.
Approved
Matched Categories: … Combined Inhibitors of Serotonin/Norepinephrine Reuptake ... Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Lopinavir

Lopinavir is an antiretroviral protease inhibitor used in combination with other antiretrovirals in the treatment of HIV-1 infection. Lopinavir is marketed and administered exclusively in combination with ritonavir - this combination, first marketed by Abbott under the brand name Kaletra in 2000, is necessary due to lopinavir's poor oral bioavailability...
Approved
Matched Description: … an antiretroviral protease inhibitor used in combination with other antiretrovirals in the treatment of ... targeted by the HIV-1 protease enzyme but which itself cannot be cleaved, thus preventing the activity of ... Ritonavir is a potent inhibitor of the enzymes responsible for lopinavir metabolism, and its co-administration …
Matched Categories: … Metabolic Side Effects of Drugs and Substances ... Antivirals used in combination for the treatment of HIV infections …

Rose bengal

Rose bengal is a pink stain derived as an analogue of fluorescein. Its disodium salt in ophthalmic solutions has been used as a diagnostic agent in suspected damage to conjunctival and corneal cells. It is also used in laboratory settings, including the preparation of Foraminifera for microscopic analysis and suppression...
Approved
Investigational
Matched Description: … Rose bengal is a pink stain derived as an analogue of fluorescein. ... and suppression of bacterial growth in several microbiological media. ... The clinical applications of rose bengal as injectable formulation under the name PV-10 in melanoma, …

Phentermine

Phentermine is a sympathomimetic amine anorectic agent and it was introduced in 1959 as part of an anti-obesity combination drug.[A174361, A174364] It is chemically related to amphetamine and it is commonly referred to as an atypical amphetamine. Phentermine has not been reported an addictive potential which allows this agent to...
Approved
Illicit
Matched Description: … ] was discontinued after finding several reports of abnormal valves in nearly 30% of the consumers. ... Phentermine is a sympathomimetic amine anorectic agent and it was introduced in 1959 as part of an anti-obesity ... This initial product, formed by the combination of phentermine with [fenfluramine] and [dexfenfluramine …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Buspirone

Buspirone is a novel anxiolytic agent with a unique structure and a pharmacological profile. Belonging to the azaspirodecanedione drug class, buspirone is a serotonin 5-HT1A receptor agonist that is not chemically or pharmacologically related to benzodiazepines, barbiturates, and other sedative/anxiolytic drugs. Unlike many drugs used to treat anxiety, buspirone does...
Approved
Investigational
Matched Description: … been used to treat anxiety disorders, such as generalized anxiety disorder (GAD), and relieve symptoms of ... It has also been used as a second-line therapy for unipolar depression when the use of selective serotonin ... [L7375] The potential use of buspirone in combination with [melatonin] in depression and cognitive impairment …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Thiopental

A barbiturate that is administered intravenously for the induction of general anesthesia or for the production of complete anesthesia of short duration. It is also used for hypnosis and for the control of convulsive states. It has been used in neurosurgical patients to reduce increased intracranial pressure. It does not...
Approved
Vet approved
Matched Description: … of complete anesthesia of short duration. ... It is also used for hypnosis and for the control of convulsive states. ... A barbiturate that is administered intravenously for the induction of general anesthesia or for the production …
Matched Categories: … combinations of barbiturates …

Benzphetamine

A sympathomimetic agent with properties similar to dextroamphetamine. It is used in the treatment of obesity. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1222)
Approved
Illicit
Matched Description: … It is used in the treatment of obesity. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1222) …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Cyclobenzaprine

Cyclobenzaprine, a centrally-acting muscle relaxant, was first synthesized in 1961 and has been available for human use since 1977. It was initially studied for use as antidepressant given its structural similarity to tricyclic antidepressants - it differs from Amitriptyline by only a single double bond.[A185039,A184982] Since its approval, it has...
Approved
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Drospirenone

Drospirenone is a synthetic progestin commonly found in the popular oral contraceptive, Yaz in combination with Ethinyl estradiol. Most recently, it was approved by both Health Canada and the FDA in combination with Estetrol as an oral contraceptive therapy.[L33199,L33174] Aside from its contraceptive effects, drospirenone is used with estrogens to...
Approved
Matched Description: … Drospirenone has been the subject of widespread safety concern due to the possibility of an increased ... risk of venous thromboembolism associated with its use. ... thromboembolism resulting from the use of drospirenone remains unclear, as studies regarding this risk …
Matched Categories: … Sex Hormones and Modulators of the Genital System …

Sertindole

Sertindole, a neuroleptic, is one of the newer antipsychotic medications available. Serdolect is developed by the Danish pharmaceutical company H. Lundbeck. It is a phenylindole derivative used in the treatment of schizophrenia. It was first marketed in 1996 in several European countries before being withdrawn two years later because of...
Approved
Investigational
Withdrawn
Matched Description: … It is a phenylindole derivative used in the treatment of schizophrenia. ... Sertindole, a neuroleptic, is one of the newer antipsychotic medications available. ... first marketed in 1996 in several European countries before being withdrawn two years later because of …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …

Pizotifen

Pizotifen belongs to the class of antamines and is related to cyproheptadine. It is a potent serotonin and tryptamine antagonist that has been used for migraine prevention for many years. It exhibits weak anticholinergic, antihistamine, and antikinin actions in addition to sedative and appetite-stimulating properties . Some patients receiving pizotifen...
Approved
Matched Description: … of its antimigraine action [A32538]. ... Pizotifen belongs to the class of antamines and is related to [cyproheptadine]. ... Sandomigran is available in a number of countries but is not approved by the FDA nor EMA. …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Displaying drugs 251 - 275 of 9510 in total