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Displaying drugs 251 - 275 of 14490 in total

Oxymetazoline

Oxymetazoline is an imidazole derivative and a potent, direct-acting alpha (α)-adrenergic agonist with affinity to both α1- and α2-adrenoceptors. Oxymetazoline is available in various formulations with a wide variety of clinical implications. The topical formulation of the drug is used to treat persistent facial redness in adults. As an effective...
Approved
Investigational
Matched Description: … affinity to both α1- and α2-adrenoceptors. ... is used for regional anesthesia during dental procedures in children and adults. ... Oxymetazoline is an imidazole derivative and a potent, direct-acting alpha (α)-adrenergic agonist with …
Matched Mixtures name: … Mucinex Sinus-Max Pressure, Pain and Cough and Mucinex Sinus-Max Severe Congestion Relief Clear and Cool …
Matched Categories: … Decongestants and Antiallergics …
Matched Products: … Up and Up nasal ... Up and up nasal ... Foster and Thrive Nasal …

Zonisamide

Zonisamide is a sulfonamide anticonvulsant used as an adjunctive therapy in adults with partial-onset seizures.[L42530,L42535] Zonisamide may act by blocking repetitive firing of voltage-gated sodium channels, leading to a reduction of T-type calcium channel currents or by binding allosterically to GABA receptors. This latter action may inhibit the uptake of...
Approved
Investigational
Matched Description: … The US and Europe approved it in 2000 and 2005, respectively.[A1379,A1383] ... [L42530,L42535] Zonisamide may act by blocking repetitive firing of voltage-gated sodium channels, leading …
Matched Categories: … Calcium-Regulating Hormones and Agents …

Cetirizine

Cetirizine, also commonly known as Zyrtec, is an orally active second-generation histamine H1 antagonist proven effective in the treatment of various allergic symptoms, such as sneezing, coughing, nasal congestion, hives, and other symptoms , . One of the most common uses for this drug is for a condition called allergic...
Approved
Matched Description: … with sleep, and other difficulties with day to day activities for many individuals [A175057]. ... in the treatment of various allergic symptoms, such as sneezing, coughing, nasal congestion, hives, and ... prevalence of allergic rhinitis in the United States is about 15% according to physician diagnoses, and …
Matched Mixtures name: … ZYRTEC D Allergy and Congestion ... Wal Zyr D Allergy and Congestion ... Cetirizine HCl and Pseudoephedrine HCl ER …
Matched Categories: … Cetirizine and isomer ... Decongestants and Antiallergics …
Matched Products: … Up and Up Allergy Relief ... Up and Up Childrens Allergy ... Up and Up All Day Allergy Relief …

Stanozolol

Stanozolol is a synthetic anabolic steroid with therapeutic uses in treating hereditary angioedema. Stanozolol is derived from testosterone, and has been abused by several high profile professional athletes.
Approved
Vet approved
Matched Description: … Stanozolol is derived from testosterone, and has been abused by several high profile professional athletes …
Matched Categories: … Alimentary Tract and Metabolism ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Idursulfase

Idursulfase is a purified form of human iduronate-2-sulfatase, a lysosomal enzyme. Idursulfase is produced by recombinant DNA technology in a human cell line. Idursulfase is an enzyme that hydrolyzes the 2-sulfate esters of terminal iduronate sulfate residues from the glycosaminoglycans dermatan sulfate and heparan sulfate in the lysosomes of various...
Approved
Matched Description: … -sulfate esters of terminal iduronate sulfate residues from the glycosaminoglycans dermatan sulfate and …
Matched Categories: … Enzymes and Coenzymes ... Alimentary Tract and Metabolism …

Benzethonium

Benzethonium is a synthetic quaternary ammonium salt with surfactant, antiseptic, and broad spectrum antimicrobial properties. Its salt form, benzethonium chloride, is primarily used as a skin disinfectant at concentrations of 0.1-0.2 %, which are safe and effective concentrations for the compound specified by the U.S. Food and Drug Administration (FDA)....
Approved
Matched Description: … It is additionally found in cosmetics and toiletries such as mouthwashes and anti-itch ointments. ... Food and Drug Administration (FDA). ... Benzethonium is a synthetic quaternary ammonium salt with surfactant, antiseptic, and broad spectrum …
Matched Mixtures name: … Gold Bond Pain and Itch ... Benzocaine and Benzethonium ... Aspiera Wound Care and Antiseptic …
Matched Categories: … Antiseptics and Disinfectants …
Matched Products: … LYSOL Healthy Touch Cleansing Green Tea and Ginger ... Foaming Instant Hand Sanitizer with Aloe and Vitamin E ... Loesch Original Kleer-Plex Antimicrobial Face and Body Wash …

Vancomycin

Antibacterial obtained from Streptomyces orientalis. It is a glycopeptide related to ristocetin that inhibits bacterial cell wall assembly and is toxic to kidneys and the inner ear. As of January 29 2018, CutisPharma's Firvanq is the only FDA approved vancomycin oral liquid treatment option available for the the treatment of...
Approved
Matched Description: … kidneys and the inner ear. ... It is a glycopeptide related to ristocetin that inhibits bacterial cell wall assembly and is toxic to ... liquid treatment option available for the the treatment of _Clostridium difficile_ associated diarrhea and …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins …
Matched Products: … Vancomycin Injection USP In 0.9% Sodium Chloride …

Deslanoside

Deacetyllanatoside C. A cardiotonic glycoside from the leaves of Digitalis lanata.
Approved

Carbamazepine

Carbamazepine, also known as Tegretol, is an anticonvulsant drug and analgesic drug used to control seizures and to treat pain resulting from trigeminal neuralgia. It was initially approved by the FDA in 1965. Aside from the above uses, this drug is also given to control the symptoms of bipolar 1....
Approved
Investigational
Matched Description: … and to treat pain resulting from trigeminal neuralgia. ... Carbamazepine, also known as Tegretol, is an anticonvulsant drug and analgesic drug used to control seizures …
Matched Categories: … Sodium Channel Blockers …

Famotidine

Famotidine is a competitive histamine-2 (H2) receptor antagonist that works to inhibit gastric acid secretion. It is commonly used in gastrointestinal conditions related to acid secretion, such as gastric ulcers and gastroesophageal reflux disease (GERD), in adults and children. Compared to other H2 receptor antagonists, famotidine displays high selectivity towards...
Approved
Matched Description: … gastroesophageal reflux disease (GERD), in adults and children. ... [A189462] Famotidine is used in various over-the-counter and off-label uses. ... It is commonly used in gastrointestinal conditions related to acid secretion, such as gastric ulcers and …
Matched Mixtures name: … Ibuprofen and famotidine ... Ibuprofen and Famotidine ... Ibuprofen and famotidine …
Matched Categories: … Alimentary Tract and Metabolism ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) …
Matched Products: … Up and Up Famotidine ... Berkley and Jensen Famotidine ... Berkley and Jensen Acid Controller …

Candesartan cilexetil

Candesartan is an angiotensin-receptor blocker (ARB) that may be used alone or with other agents to treat hypertension. It is administered orally as the prodrug, candesartan cilexetil, which is rapidly converted to its active metabolite, candesartan, during absorption in the gastrointestinal tract. Candesartan lowers blood pressure by antagonizing the renin-angiotensin-aldosterone...
Approved
Matched Description: … RAAS); it competes with angiotensin II for binding to the type-1 angiotensin II receptor (AT1) subtype and ... an alternative agent for the treatment of heart failure, systolic dysfunction, myocardial infarction and ... Candesartan may be used to treat hypertension, isolated systolic hypertension, left ventricular hypertrophy and …
Matched Mixtures name: … Candesartan Cilexetil and Hydrochlorothiazide ... Candesartan Cilexetil and Hydrochlorothiazide ... Candesartan Cilexetil and Hydrochlorothiazide …
Matched Categories: … Angiotensin II Antagonists and Diuretics …

Indapamide

The most significant modifiable risk factor for cardiovascular disease and the most prominent contributor to all-cause mortality is hypertension. Characterized by an office blood pressure of ≥140/90, hypertension is pervasive and impacts an estimated 25% of adults globally. Treatment for hypertension should include a number of lifestyle changes (ie. reduced...
Approved
Matched Description: … [A204155] Treatment for hypertension should include a number of lifestyle changes (ie. reduced sodium ... The most significant modifiable risk factor for cardiovascular disease and the most prominent contributor ... [A204155] Characterized by an office blood pressure of ≥140/90, hypertension is pervasive and impacts …
Matched Categories: … Sodium Chloride Symporter Inhibitors ... Genito Urinary System and Sex Hormones ... perindopril, amlodipine and indapamide ... rosuvastatin, perindopril and indapamide ... perindopril, bisoprolol, amlodipine and indapamide …

Abiraterone

Abiraterone is a potent, irreversible, and selective inhibitor of 17 αhydroxylase/C17,20-lyase (CYP17), an enzyme expressed in testicular, adrenal, and prostatic tumour tissues, to regulate androgen biosynthesis.[A3811, A260880, L40968] Abiraterone was first approved by the FDA and EMA on April, July, and September 2011, respectively. It is used to treat metastatic...
Approved
Matched Description: … ] and September 2011,[A260880] respectively. ... Abiraterone is a potent, irreversible, and selective inhibitor of 17 αhydroxylase/C17,20-lyase (CYP17 ... [L40968, L40193, L47740, L47745] As abiraterone has poor oral bioavailability and is susceptible to …
Matched Categories: … niraparib and abiraterone ... abiraterone and prednisolone ... Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents ... Metabolic Side Effects of Drugs and Substances …

Rose bengal I-131

Approved
Matched Salts name: … Rose bengal sodium I-131 …

Fosnetupitant

In April 2018, the U.S. Food and Drug Administration (FDA) and the Swiss company Helsinn approved the intravenous formulation of AKYNZEO® (NEPA, a fixed antiemetic combination of fosnetupitant, 235mg, and palonosetron, 0.25mg) as an alternative treatment option for patients experiencing chemotherapy-induced nausea and vomiting . Fosnetupitant is the pro-drug form...
Approved
Matched Description: … Food and Drug Administration (FDA) and the Swiss company Helsinn approved the intravenous formulation ... of AKYNZEO® (NEPA, a fixed antiemetic combination of fosnetupitant, 235mg, and palonosetron, 0.25mg) ... as an alternative treatment option for patients experiencing chemotherapy-induced nausea and vomiting …
Matched Categories: … Netupitant and prodrug …

Folic acid

Folic acid, also known as folate or Vitamin B9, is a member of the B vitamin family and an essential cofactor for enzymes involved in DNA and RNA synthesis. More specifically, folic acid is required by the body for the synthesis of purines, pyrimidines, and methionine before incorporation into DNA...
Approved
Nutraceutical
Vet approved
Matched Description: … Levoleucovorin and leucovorin are analogs of tetrahydrofolate (THF) and are able to bypass DHFR reduction ... cofactor for enzymes involved in DNA and RNA synthesis. ... therefore prevent the formation of DHF and THF. …
Matched Mixtures name: … Sodium polysulthionate and folic acid ... Sodium Polysulthionate and Folic Acid ... and Succinic Acid …
Matched Salts name: … Folate sodium …
Matched Categories: … Diet, Food, and Nutrition ... Folic Acid and Derivatives ... Vitamin B12 and Folic Acid ... ferrous sulfate and folic acid ... ferrous fumarate and folic acid …

Xylometazoline

Xylometazoline is an imidazoline derivative with sympathomimetic and nasal decongestant activity. Xylometazoline works by binding to alpha (α)-adrenergic receptors to cause vasoconstriction of nasal blood vessels. Xylometazoline is available in over-the-counter (OTC) nasal sprays or drops to temporarily relieve nasal congestion due to cold, hay fever or other respiratory allergies....
Approved
Investigational
Matched Description: … Xylometazoline is an imidazoline derivative [A228523] with sympathomimetic and nasal decongestant activity …
Matched Categories: … Decongestants and Antiallergics …
Matched Products: … Cold and Allergy Decongestant Nasal Spray ... Otrivin Cold and Allergy Decongestant Nose Drops ... Otrivin Allergy and Cold Decongestant Nasal Spray …

Acetazolamide

One of the carbonic anhydrase inhibitors that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is...
Approved
Vet approved
Matched Description: … (From Smith and Reynard, Textbook of Pharmacology, 1991, p337) ... It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures ... anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and …
Matched Salts name: … Acetazolamide sodium …
Matched Categories: … Antiglaucoma Preparations and Miotics ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …

Azlocillin

Azlocillin is a semisynthetic ampicillin-derived acylureido penicillin.
Approved
Matched Salts name: … Azlocillin sodium …

Dehydrocholic acid

Dehydrocholic acid is a synthetic bile acid that was prepared from the oxidation of cholic acid with chromic acid . It has been used for stimulation of biliary lipid secretion. The use of dehydrocholic acid in over-the-counter products has been discontinued by Health Canada.
Approved
Investigational
Matched Salts name: … Dehydrocholate sodium …
Matched Categories: … Bile Acids and Salts ... Cholagogues and Choleretics …

Clotrimazole

This drug is a broad spectrum antimycotic or antifungal agent. Clotrimazole's antimycotic properties were discovered in the late 1960s . Clotrimazole falls under the imidazole category of azole antifungals, possessing broad-spectrum antimycotic activity . It is available in various preparations, including creams, pessaries, and troche formulations (slowly dissolving tablets). As...
Approved
Vet approved
Matched Description: … It is available in various preparations, including creams, pessaries, and troche formulations (slowly ... has become a drug of interest in treating several other diseases such as sickle cell disease, malaria and ... The minimal side effect profile of this drug and its uncomplicated metabolic profile have led it to gain …
Matched Mixtures name: … Clotrimazole and Betamethasone Dipropionate ... Clotrimazole and Betamethasone Dipropionate ... Clotrimazole and Betamethasone Dipropionate …
Matched Categories: … Imidazole and Triazole Derivatives ... Gynecological Antiinfectives and Antiseptics ... Antiinfectives and Antiseptics for Local Oral Treatment ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Kerasal foot and toe ... Up and Up Athletes Foot ... Protective Nail and skin …

Testosterone

Testosterone is a steroid sex hormone indicated to treat primary hypogonadism and hypogonadotropic hypogonadism.[L8983,L8935,L8938,L8986,L8989,L8992,L8995] Testosterone antagonizes the androgen receptor to induce gene expression that causes the growth and development of masculine sex organs and secondary sexual characteristics.[A187114,L8983,L8935,L8938,L8986,L8989,L8992,L8995] Testosterone was isolated from samples and also synthesized in 1935.
Approved
Investigational
Matched Description: … development of masculine sex organs and secondary sexual characteristics. ... Testosterone is a steroid sex hormone indicated to treat primary hypogonadism and hypogonadotropic hypogonadism ... [A187114,L8983,L8935,L8938,L8986,L8989,L8992,L8995] Testosterone was isolated from samples and also …
Matched Categories: … Androgens and Estrogens ... testosterone and estrogen ... Testosterone and derivatives ... Genito Urinary System and Sex Hormones ... Sex Hormones and Modulators of the Genital System …

Rucaparib

Rucaparib is an anticancer drug and poly (ADP-ribose) polymerase (PARP) inhibitor. PARP is an enzyme that plays an essential role in DNA repair. Rucaparib is proposed to work in several PARP-dependent and PARP-independent mechanisms of action; however, it causes a unique effect of synthetic lethality. By targeting the genetically-mutated cancer...
Approved
Investigational
Matched Description: … Rucaparib is an anticancer drug and poly (ADP-ribose) polymerase (PARP) inhibitor. ... [L42185] It is currently used to treat recurrent ovarian and prostate cancer in adults. ... [A18745] Rucaparib is proposed to work in several PARP-dependent and PARP-independent mechanisms of action …
Matched Salts name: … Rucaparib phosphate …
Matched Categories: … Antineoplastic and Immunomodulating Agents …

Castor oil

Castor oil is a vegetable oil obtained by pressing the seeds of the castor oil plant (Ricinus communis L.) mainly cultivated in India, South America, Africa, and China. Castor oil is a rich source of DB02955, which represents up to 90% of the total castor oil content. It also consists...
Approved
Investigational
Nutraceutical
Vet approved
Matched Description: … cosmetic, hair, and skincare products. ... and mineral oral tablets as an ingredient for protective coatings. ... of the castor oil plant (_Ricinus communis_ L.) mainly cultivated in India, South America, Africa, and …
Matched Mixtures name: … Zinc and Castor Oil Crm ... Zinc and Castor Oil Cream BP …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Foster and Thrive Castor Oil …

Titanium dioxide

Titanium dioxide, also known as titanium(IV) oxide or titania, is the naturally occurring oxide of titanium. It is used as a pigment under the names titanium white, Pigment White 6 (PW6), or CI 77891. It is typically extracted from ilmenite, rutile and anatase.
Approved
Matched Description: … It is typically extracted from ilmenite, rutile and anatase. …
Matched Mixtures name: … Sodium Sulfacetamide Sulfur ... Anhydrous SPF 30 ... Dermaroller Anhydrous Sunscreen SPF 30 …
Matched Categories: … Astringents and Deodorants …
Matched Products: … Im Safe for Baby and Silver ... Peaufinee Baby and Kids Sun ... Dermablend Leg and Body Cover …
Displaying drugs 251 - 275 of 14490 in total