Did you mean bitopertin of ro 493838 of r 18 of ビトペルチン?
Displaying drugs 2851 - 2875 of 9611 in total
Phenelzine
Phenelzine, with the formula β-phenylethylhydrazine, is a monoamine oxidase inhibiting antidepressant that is effective in the treatment of panic disorder and social anxiety disorder. It was developed by Parke Davis and originally FDA approved on June 9th, 1961. It is currently approved under prescription by the name of Nardil.
Approved
Matched Description: … It is currently approved under prescription by the name of Nardil. ... β-phenylethylhydrazine, is a monoamine oxidase inhibiting antidepressant that is effective in the treatment of …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Dihydroergotamine
A 9,10alpha-dihydro derivative of ergotamine. Dihydroergotamine is used as an abortive therapy for migraines. Its use has largely been supplanted by triptans in current therapy due to the class's greater selectivity and more favourable side effect profile.
Recent improvements have been made in the design of intranasal delivery devices allowing...
Approved
Investigational
Matched Description: … 3-fold in Cmax and 4-fold in AUC despite the solution formulated at 75% of the strength of the existing ... A 9,10alpha-dihydro derivative of [ergotamine]. ... delivery of dihydroergotamine solution to the vasculature-rich upper nasal cavity. …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Trimethoprim
Trimethoprim is an antifolate antibacterial agent that inhibits bacterial dihydrofolate reductase (DHFR), a critical enzyme that catalyzes the formation of tetrahydrofolic acid (THF) - in doing so, it prevents the synthesis of bacterial DNA and ultimately continued bacterial survival. Trimethoprim is often used in combination with sulfamethoxazole due to their...
Approved
Vet approved
Matched Description: … that inhibits bacterial dihydrofolate reductase (DHFR), a critical enzyme that catalyzes the formation of ... tetrahydrofolic acid (THF) - in doing so, it prevents the synthesis of bacterial DNA and ultimately ... complementary and synergistic mechanisms but may be used as a monotherapy in the treatment and/or prophylaxis of …
Matched Mixtures name: … SOLASTEM(R) TABLETAS ... MEDIPRIM F (R) TABLETA ... MEDIPRIM F (R) TABLETA …
Matched Categories: … Metabolic Side Effects of Drugs and Substances …
Matched Mixtures name: … SOLASTEM(R) TABLETAS ... MEDIPRIM F (R) TABLETA ... MEDIPRIM F (R) TABLETA …
Matched Categories: … Metabolic Side Effects of Drugs and Substances …
Rifabutin
A broad-spectrum antibiotic that is being used as prophylaxis against disseminated Mycobacterium avium complex infection in HIV-positive patients.
Approved
Investigational
Matched Categories: … Drugs for Treatment of Tuberculosis …
Primidone
Primidone is an anticonvulsant used to treat essential tremor as well as grand mal, psychomotor, and focal epileptic seizures. Primidone was developed by J Yule Bogue and H C Carrington in 1949. Primidone was granted FDA Approval on 8 March 1954.
Approved
Vet approved
Matched Categories: … combinations of barbiturates …
Benzoyl peroxide
Benzoyl peroxide is a commonly used drug in topical treatments for acne.[L33249,L33264,L33269,L33299,L33314] It has been formulated as products with either a single active ingredient,[L33249,L33299] or with erythromycin, clindamycin, or adapalene. After administration, the peroxide bond is cleaved, allowing benzoyloxy radicals to nonspecifically interact with proteins.[A18903,A233859] This treatment decreases keratin and...
Approved
Matched Description: … A233859] This treatment decreases keratin and sebum around follicles, as well as increasing turnover of …
Matched Mixtures name: … R+f Paired Regimen for Wrinkles + Occasional Acne …
Matched Products: … BENZAC(R) AC 2 1/2 ... NeoBenz(R) Micro Benzoyl Peroxide Wash, 7% …
Matched Mixtures name: … R+f Paired Regimen for Wrinkles + Occasional Acne …
Matched Products: … BENZAC(R) AC 2 1/2 ... NeoBenz(R) Micro Benzoyl Peroxide Wash, 7% …
Tobramycin
Aminoglycosides, many of which are derived directly from Streptomyces spp., are concentration-dependent bactericidal antibiotics with a broad spectrum of activity against Gram-positive and Gram-negative organisms. Inhaled tobramycin is notable for its use in treating chronic Pseudomonas aeruginosa infections in cystic fibrosis patients, as P. aeruginosa is notoriously inherently resistant to...
Approved
Investigational
Matched Description: … Aminoglycosides, many of which are derived directly from _Streptomyces_ spp., are concentration-dependent ... L32739] However, tobramycin can also be administered intravenously and topically to treat a variety of ... bactericidal antibiotics with a broad spectrum of activity against Gram-positive and Gram-negative organisms …
Matched Mixtures name: … GOTABIOTIC(R)F OFTALMICO …
Matched Mixtures name: … GOTABIOTIC(R)F OFTALMICO …
Losartan
Losartan is an angiotensin II receptor blocker (ARB) used to treat hypertension. Angiotensin-converting enzyme (ACE) inhibitors are used for a similar indication but are associated with a cough. When patients with ACE inhibitor associated coughs are switched to ARBs like losartan, they have an incidence of cough similar to placebo...
Approved
Matched Description: … patients with ACE inhibitor associated coughs are switched to ARBs like losartan, they have an incidence of ... [L7423] Losartan is available as losartan potassium oral tablets as well as a combination tablet of losartan …
Matched Products: … ATRELAN (R) 50MG/TABLETAS …
Matched Products: … ATRELAN (R) 50MG/TABLETAS …
Salicylic acid
A compound obtained from the bark of the white willow and wintergreen leaves, and also prepared synthetically. It has bacteriostatic, fungicidal, and keratolytic actions. Its salts, the salicylates, are used as analgesics.
Approved
Investigational
Vet approved
Matched Description: … A compound obtained from the bark of the white willow and wintergreen leaves, and also prepared synthetically …
Matched Products: … R-044 Blemish Fix ... Fruit of the Earth Acne Wash …
Matched Products: … R-044 Blemish Fix ... Fruit of the Earth Acne Wash …
Chondroitin sulfate
Chondroitin sulfate is a glycosaminoglycan considered as a symptomatic slow-acting drug for osteoarthritis (SYSADOA). The SYSADOA status suggested a pain relief and increased joint mobility after a relative long regular administration, as well as a long-lasting effect after the end of the treatment. Chondroitin sulfate is composed of alternating 1,3-N-acetyl-β-d-galactosamine...
Approved
Investigational
Nutraceutical
Matched Description: … Chondroitin sulfate is composed of alternating 1,3-N-acetyl-β-d-galactosamine and 1,4-β-d-glucuronic ... mobility after a relative long regular administration, as well as a long-lasting effect after the end of ... acid units which bear 4-O- and/or 6-O-sulfations at the N-acetylgalactosamine units disposed of in specific …
Matched Mixtures name: … ARTROFORT(R) COMPLEX …
Matched Mixtures name: … ARTROFORT(R) COMPLEX …
Rimexolone
Rimexolone is a 1% eye drop solution is a glucocorticoid steroid. It is used to treat inflammation in the eye. It is marketed as Vexol.
Approved
Rebamipide
Rebamipide has been investigated for the treatment of Stomach Ulcer, Keratoconjunctivitis Sicca, and Gastric Adenoma and Early Gastric Cancer.
Approved
Investigational
Matched Description: … Rebamipide has been investigated for the treatment of Stomach Ulcer, Keratoconjunctivitis Sicca, and …
Amylocaine
Despite the introduction of using cocaine injections for regional anesthesia in 1884, non-addictive substitutes were sought after immediately . Finally, in 1903 the world's first synthetic and non-addictive local anesthetic, amylocaine, was synthesized and patented under the name Forneaucaine by Ernest Fourneau at the Pasteur Institute . Elsewhere in English...
Approved
Withdrawn
Matched Description: … Despite the introduction of using cocaine injections for regional anesthesia in 1884, non-addictive substitutes ... Elsewhere in English speaking countries it was referred to as Stovaine, given the meaning of the French ... possessed less severe side effects than cocaine [L1882], the eventual development and clinical use of …
Gefitinib
Gefitinib (originally coded ZD1839) is a drug used in the treatment of certain types of cancer. Acting in a similar manner to erlotinib (marketed as Tarceva), gefitinib selectively targets the mutant proteins in malignant cells. It is marketed by AstraZeneca under the trade name Iressa.
Approved
Investigational
Matched Description: … Gefitinib (originally coded ZD1839) is a drug used in the treatment of certain types of cancer. …
Clove oil
Clove oil is obtained by extraction from the dried flower buds of the clove plant. Traditionally, it has been used as a flavouring spice in foods, or as a fragrance. It is also found in topical analgesics. Clove oil has shown to exert some antimicrobial activities. The antioxidant and antimicrobial...
Approved
Nutraceutical
Matched Description: … state of _Bahia_. ... The antioxidant and antimicrobial activity of clove is higher than that of many fruits, vegetables, and ... Clove is native of Indonesia but is now cultured in several parts of the world, including Brazil in the …
Amprenavir
Amprenavir is a protease inhibitor used to treat HIV infection.
Approved
Investigational
Matched Categories: … Drugs for Treatment of Tuberculosis …
Asenapine
Developed by Schering-Plough after its merger with Organon International, asenapine is a sublingually administered, atypical antipsychotic for treatment of schizophrenia and acute mania associated with bipolar disorder. Asenapine also belongs to the dibenzo-oxepino pyrrole class. It is also for severe post-traumatic stress disorder nightmares in soldiers as an off-label use....
Approved
Matched Description: … Organon International, asenapine is a sublingually administered, atypical antipsychotic for treatment of …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Celecoxib
Celecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, is a nonsteroidal anti-inflammatory drug (NSAID) which is known for its decreased risk of causing gastrointestinal bleeding compared to other NSAIDS. It is used to manage symptoms of various types of arthritis pain and in familial adenomatous polyposis (FAP) to reduce precancerous polyps in...
Approved
Investigational
Matched Description: … [A181544] It is used to manage symptoms of various types of arthritis pain and in familial adenomatous ... ) inhibitor, is a nonsteroidal anti-inflammatory drug (NSAID) which is known for its decreased risk of ... evaluated as potential cancer chemopreventive and therapeutic drugs in clinical trials for a variety of …
Matched Categories: … combinations of sulfonamides …
Matched Categories: … combinations of sulfonamides …
Buprenorphine
Buprenorphine is a weak partial mu-opioid receptor agonist and a weak kappa-opioid receptor antagonist used for the treatment of severe pain.[A186283,A186292] It is also commonly used as an alternative to methadone for the treatment of severe opioid addiction. Buprenorphine is commercially available as the brand name product Suboxone which is...
Approved
Illicit
Investigational
Vet approved
Matched Description: … agent for the treatment of conditions requiring high doses of strong opioids. ... Provision of OAT is often combined with education about harm reduction including use of clean needles ... The intention of substitution of illicit opioids with the long-acting opioids used in OAT is to prevent …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Methotrimeprazine
A phenothiazine with pharmacological activity similar to that of both chlorpromazine and promethazine. It has the histamine-antagonist properties of the antihistamines together with central nervous system effects resembling those of chlorpromazine. (From Martindale, The Extra Pharmacopoeia, 30th ed, p604)
Approved
Investigational
Matched Description: … effects resembling those of chlorpromazine. ... A phenothiazine with pharmacological activity similar to that of both chlorpromazine and promethazine ... It has the histamine-antagonist properties of the antihistamines together with central nervous system …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Aminolevulinic acid
A compound produced from succinyl-CoA and glycine as an intermediate in heme synthesis. It is used as a photochemotherapy for actinic keratosis. [PubChem]
Approved
Ranibizumab
Ranibizumab is a recombinant humanized IgG1 kappa isotype monoclonal antibody fragment directed against human vascular endothelial growth factor A (VEGF-A), which is a glycoprotein implicated in the pathophysiology of age-related macular degeneration.[A2301, L38978] Ranibizumab is used to treat various ocular disorders with abnormal growth of blood vessels, such as neovascular...
Approved
Matched Description: … only biosimilar drug of ranibizumab available in Canada. ... vascular endothelial growth factor A (VEGF-A), which is a glycoprotein implicated in the pathophysiology of ... The development of ranibizumab first began after [bevacizumab], another anti-VEGF anticancer drug, was …
Ramucirumab
Ramucirumab is a human monoclonal antibody (IgG1) against vascular endothelial growth factor receptor 2 (VEGFR2), a type II trans-membrane tyrosine kinase receptor expressed on endothelial cells. By binding to VEGFR2, ramucirumab prevents binding of its ligands (VEGF-A, VEGF-C, and VEGF-D), thereby preventing VEGF-stimulated receptor phosphorylation and downstream ligand-induced proliferation, permeability,...
Approved
Investigational
Matched Description: … By binding to VEGFR2, ramucirumab prevents binding of its ligands (VEGF-A, VEGF-C, and VEGF-D), thereby ... other agents directed against VEGFR-2, ramucirumab binds a specific epitope on the extracellular domain of ... VEGF-stimulated receptor phosphorylation and downstream ligand-induced proliferation, permeability, and migration of …
Displaying drugs 2851 - 2875 of 9611 in total