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Displaying drugs 2901 - 2925 of 9608 in total
Mecasermin rinfabate
Mecasermin rinfabate is approved for severe primary insulin-like growth factor (IGF) deficiency or in patients with GH gene deletion who have developed antibodies to growth hormone (GH) . Mecasermin rinfabate is similar to DB01277 in that both drugs contain recombinant DNA origin insulin-like growth factor 1 (IGF-1). Mecasermin rinfabate however,...
Approved
Matched Description: … The binding of IGF-1 to IGFBP-3 is said to extend the half life and reduce the clearance of IGF-1 in ... patients with growth hormone resistant syndromes and low levels of IGFBP-3 though this may represent …
Clascoterone
Clascoterone (cortexolone 17α-propionate, CB-03-01) is a novel antagonist of androgen receptors. It binds to androgen receptors with high affinity. By competing with androgens for binding to androgen receptors, clascoterone works by blocking the androgen receptor signalling cascades that promote acne pathogenesis, such as sebaceous gland proliferation, excess sebum production, and...
Approved
Investigational
Matched Description: … Clascoterone (cortexolone 17α-propionate, CB-03-01) is a novel antagonist of androgen receptors. ... [A218846] In August 2020, FDA approved clascoterone for the first-in-class topical treatment of acne …
Mometasone furoate
Mometasone furoate is a corticosteroid drug that can be used for the treatment of asthma, rhinitis, and certain skin conditions[FDA Label][F4292,F4295]. It has a glucocorticoid receptor binding affinity 22 times stronger than dexamethasone and higher than many other corticosteroids as well . Mometasone furoate is formulated as a dry powder...
Approved
Investigational
Vet approved
Matched Description: … Mometasone furoate is a corticosteroid drug that can be used for the treatment of asthma, rhinitis, and …
Mucor racemosus
Mucor racemosus is a fungus which can provoke allergic reactions. Mucor racemosus extract is used in allergenic testing.
Approved
Riltozinameran
The Omicron variant of SARS-CoV-2 is a variant of concern that was first reported in November 2021. It tends to cause less severe disease but is significantly more virulent than both the original virus and earlier variants (e.g. Delta). As of November 2022, it is the primary circulating variant of...
Approved
Investigational
Matched Description: … The Omicron variant of SARS-CoV-2 is a variant of concern that was first reported in November 2021. ... [L43917] As of November 2022, it is the primary circulating variant of concern according to the World ... [L43917]
Riltozinameran is an mRNA vaccine encoding the S glycoprotein of SARS-CoV-2 Omicron variant …
Bromazepam
One of the benzodiazepines that is used in the treatment of anxiety disorders. It is a Schedule IV drug in the U.S. and Canada and under the Convention on Psychotropic Substances. It is a intermediate-acting benzodiazepine.
Approved
Illicit
Investigational
Matched Description: … One of the benzodiazepines that is used in the treatment of anxiety disorders. …
Respiratory syncytial virus vaccine, adjuvanted
Arexvy (respiratory syncytial virus vaccine, adjuvanted) is an adjuvanted vaccine developed by GlaxoSmithKline Biologicals. It comprises lyophilized recombinant respiratory syncytial virus glycoprotein F (RSVPreF3) stabilized in pre-fusion conformation as the antigen component, which is reconstituted at the time of use with the accompanying vial of AS01E adjuvant as the adjuvant...
Approved
Matched Description: … use with the accompanying vial of AS01E adjuvant as the adjuvant suspension component. ... stabilized in pre-fusion conformation as the antigen component, which is reconstituted at the time of …
Lubiprostone
Lubiprostone is a medication used in the management of idiopathic chronic constipation. A prostaglandin E1 derivative, lubiprostone is a bicyclic fatty acid that activates ClC-2 chloride channels located on the apical side of the gastrointestinal epithelial cells. Activation of these channels promotes the secretion of a chloride-rich fluid that soften...
Approved
Investigational
Matched Description: … Activation of these channels promotes the secretion of a chloride-rich fluid that soften the stool, increase ... Lubiprostone is a medication used in the management of idiopathic chronic constipation. ... lubiprostone is a bicyclic fatty acid that activates ClC-2 chloride channels located on the apical side of …
Midazolam
Midazolam is a short-acting hypnotic-sedative drug with anxiolytic, muscle relaxant, anticonvulsant, sedative, hypnotic, and amnesic properties. It belongs to a class of drugs called benzodiazepines. This drug is unique from others in this class due to its rapid onset of effects and short duration of action. Midazolam is available by...
Approved
Illicit
Matched Description: … This drug is unique from others in this class due to its rapid onset of effects and short duration of ... [L45098] In May 2019, the nasal spray of midazolam was approved for the acute treatment of distinctive ... [A173842] It belongs to a class of drugs called _benzodiazepines_. …
Perhexiline
Perhexiline is a coronary vasodilator used especially for angina of effort. It may cause neuropathy and hepatitis.
Approved
Investigational
Matched Description: … Perhexiline is a coronary vasodilator used especially for angina of effort. …
Fingolimod
Multiple sclerosis, or MS, is a devastating inflammatory disease that often progresses and causes severe neurological, physical, and cognitive effects. Fingolimod is a sphingosine 1-phosphate receptor modulator for the treatment of relapsing-remitting multiple sclerosis. It was developed by Novartis and initially approved by the FDA in 2010. Fingolimod was also...
Approved
Investigational
Matched Description: … [L12651] Fingolimod was also studied for the treatment of COVID-19, the disease caused by infection with ... [A176474] Fingolimod is a sphingosine 1-phosphate receptor modulator for the treatment of relapsing-remitting …
Telotristat ethyl
Telotristat ethyl is a prodrug of telotristat that was approved by the FDA in March 2017 as Xermelo. It was previously referred to as telotristat etiprate, the hippurate salt form; however, the FDA recommends the use of the name of the neutral form rather than that of the salt.[A252937, A252942]...
Approved
Investigational
Matched Description: … the name of the neutral form rather than that of the salt. ... over the course of the disease. ... [L43367] Overexposure to serotonin can cause severe diarrhea, one of the main clinical symptoms of carcinoid …
Choline salicylate
Choline salicylate is an anti-inflammatory pain reliever agent that is related to aspirin. It is used to decrease swelling and to treat mild-moderate pain. It is used to treat arthritis in both children and adults. This medicine can also be used for fever .
Choline Salicylate is the choline salt...
Approved
Nutraceutical
Matched Description: … The UK government has regulated its use, due to toxicity in those under 16 years of age. ... Choline salicylate is effective in the treatment of gout, rheumatic fever, rheumatoid arthritis and muscle ... Choline Salicylate is the choline salt of salicylic acid, used as an analgesic, antipyretic and antirheumatic …
Vorinostat
Vorinostat (rINN) or suberoylanilide hydroxamic acid (SAHA), is a drug currently under investigation for the treatment of cutaneous T cell lymphoma (CTCL), a type of skin cancer, to be used when the disease persists, gets worse, or comes back during or after treatment with other medicines. It is the first...
Approved
Investigational
Matched Description: … It is the first in a new class of agents known as histone deacetylase inhibitors. ... Further brain tumor trials are planned using combinations of vorinostat with other drugs. ... or suberoylanilide hydroxamic acid (SAHA), is a drug currently under investigation for the treatment of …
Pravastatin
Pravastatin is the 6-alpha-hydroxy acid form of mevastatin. Pravastatin was firstly approved in 1991 becoming the second available statin in the United States. It was the first statin administered as the active form and not as a prodrug. This drug was developed by Sankyo Co. Ltd.; however, the first approved...
Approved
Matched Description: … Pravastatin is the 6-alpha-hydroxy acid form of [mevastatin]. ... The manufacturing process is followed by the hydrolysis of the lactone group and the biological hydroxylation …
Tadalafil
Tadalafil is a selective phosphodiesterase-5 inhibitor that is used in the treatment of erectile dysfunction (ED), pulmonary arterial hypertension (PAH), and benign prostatic hypertrophy.[L39100, L39105] It was first approved in 2003 by the FDA for use in ED and later in 2009 for PAH. In contrast to other PDE5 inhibitors...
Approved
Investigational
Matched Description: … Tadalafil is a selective phosphodiesterase-5 inhibitor that is used in the treatment of erectile dysfunction ... longer half-life which has made it a more suitable option for chronic once-daily dosing in the treatment of …
Matched Products: … VERELIS(R) 20 MG TABLETA RECUBIERTA …
Matched Products: … VERELIS(R) 20 MG TABLETA RECUBIERTA …
Bromhexine
Bromhexine is mucolytic agent used for a variety of respiratory conditions associated with increased mucus secretion. It is derived from the Adhatoda vasica plant and aids in the clearance of excess mucus, improving breathing and reducing cough. It was introduced into the market in 1963, and is widely available as...
Approved
Matched Description: … Bromhexine is mucolytic agent used for a variety of respiratory conditions associated with increased ... It is derived from the Adhatoda vasica plant and aids in the clearance of excess mucus, improving breathing ... bromhexine and its metabolite [ambroxol] have garnered interest for the potential prevention and treatment of …
Choline C-11
Choline C 11 Injection is a radioactive diagnostic agent for positron emission tomography (PET) imaging of pat ients with suspected prostate cancer recurrence and non-informative bone scintigraphy, computerized tomography (CT) or magnetic resonance imaging.
Approved
Matched Description: … Choline C 11 Injection is a radioactive diagnostic agent for positron emission tomography (PET) imaging of …
Linzagolix
Linzagolix is a non-peptide, selective antagonist of the gonadotropin-releasing hormone (GnRH) receptor. It has been studied for the treatment of estrogen-dependent conditions such as uterine fibroids and endometriosis.[A253642,A253647] It is similar to other GnRH receptor antagonists like cetrorelix, relugolix, and elagolix.
Uterine fibroids occur in >70% of women of reproductive...
Approved
Matched Description: … Uterine fibroids occur in >70% of women of reproductive age, and when symptomatic are associated with ... Linzagolix is a non-peptide, selective antagonist of the gonadotropin-releasing hormone (GnRH) receptor ... [A253667]
Linzagolix was approved for use in the European Union in June 2022 for the management of …
Dalbavancin
Dalbavancin is a second-generation lipoglycopeptide antibiotic that was designed to improve on the natural glycopeptides currently available, such as vancomycin and teicoplanin [A4072, A4073]. Modifications from these older glycoprotein classes facilitated a similar mechanism of action for dalbavancin but with increased activity and once-weekly dosing [FDA Label, F2356, A4072, A4073]....
Approved
Investigational
Matched Description: … Its use is indicated for the treatment of acute bacterial skin and skin structure infections (ABSSSI) ... Modifications from these older glycoprotein classes facilitated a similar mechanism of action for dalbavancin ... acts by interfering with bacterial cell wall synthesis by binding to the D-alanyl-D-alanine terminus of …
Adenosine
The structure of adenosine was first described in 1931, though the vasodilating effects were not described in literature until the 1940s. Adenosine is indicated as an adjunct to thallium-201 in myocardial perfusion scintigraphy, though it is rarely used in this indication, having largely been replaced by dipyridamole and [regadenson].[A229833,A229838] Adenosine...
Approved
Investigational
Matched Description: … The structure of adenosine was first described in 1931,[A229823] though the vasodilating effects were ... [A229833,A229838] Adenosine is also indicated in the treatment of supraventricular tachycardia. …
Matched Mixtures name: … Plalab Placenta R-20 …
Matched Mixtures name: … Plalab Placenta R-20 …
Conivaptan
Conivaptan is a non-peptide inhibitor of antidiuretic hormone (vasopressin). It was approved in 2004 for hyponatremia (low blood sodium levels) caused by syndrome of inappropriate antidiuretic hormone (SIADH). Conivaptan inhibits both isotypes of the vasopressin receptor (V1a and V2).
Approved
Investigational
Matched Description: … Conivaptan is a non-peptide inhibitor of antidiuretic hormone (vasopressin). ... Conivaptan inhibits both isotypes of the vasopressin receptor (V1a and V2). ... It was approved in 2004 for hyponatremia (low blood sodium levels) caused by syndrome of inappropriate …
Edoxudine
Edoxudine is a deoxythymidine analog with activity against herpes simplex virus. It is a potent and selective inhibitor of herpes simplex virus type 1 and 2. The obtained product is an antiviral ointment. The activity of edoxudine against herpes simplex virus was first recognized in 1967. It was later recognized...
Approved
Investigational
Withdrawn
Matched Description: … It is a potent and selective inhibitor of herpes simplex virus type 1 and 2. ... [L2407] The activity of edoxudine against herpes simplex virus was first recognized in 1967. ... It was later recognized to be effective in vivo in a preclinical model of keratitis caused by herpes …
Thimerosal
Thiomersal (INN), commonly known in the U.S. as thimerosal, is an organomercury compound. This compound is a well-established and widely used antiseptic and antifungal agent.
Developed in 1927, thimerosal has been and is still being used as a preservative in some cosmetics, topical pharmaceuticals, and biological drug products, which includes...
Approved
Insulin lispro
Insulin lispro is a rapid-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the pancreas...
Approved
Matched Description: … high levels of insulin in a short period of time to mimic the release of endogenous insulin from the ... , with a goal of avoiding any periods of hypoglycemia. ... Insulin lispro is a rapid-acting form of insulin used for the treatment of hyperglycemia caused by Type …
Displaying drugs 2901 - 2925 of 9608 in total