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Displaying drugs 276 - 300 of 11645 in total

Tarlatamab

Tarlatamab is a first-in-class T-cell engager used to treat extensive-stage small cell lung cancer. It is a bispecific monoclonal antibody that targets CD3 expressed on the surface of T-cells and delta-like ligand 3 (DLL3), an inhibitory ligand that suppresses Notch signaling and is highly expressed across various SCLC disease stages...
Approved
Investigational
Matched Synonyms: … ligand 3)) and anti-(homo sapiens cd3e (cd3 epsilon, leu-4)), monoclonal antibody single chain (scfv)2- …

Afatinib

Afatinib is a 4-anilinoquinazoline tyrosine kinase inhibitor in the form of a dimaleate salt available as Boehringer Ingelheim's brand name Gilotrif [FDA Label]. For oral use, afatinib tablets are a first-line (initial) treatment for patients with metastatic non-small cell lung cancer (NSCLC) with common epidermal growth factor receptor (EGFR) mutations...
Approved
Matched Iupac: … -N-{4-[(3-chloro-4-fluorophenyl)amino]-7-[(3S)-oxolan-3-yloxy]quinazolin-6-yl}-4-(dimethylamino)but-2- …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … GIOTRIF 20 MG FILM KAPLI TABLET ,TABLET, 28 ADET ... GIOTRIF 30 MG FILM KAPLI TABLET ,TABLET, 28 ADET ... GIOTRIF 40 MG FILM KAPLI TABLET ,TABLET, 28 ADET …

Azilsartan medoxomil

Azilsartan medoxomil is a prodrug that is broken down to azilsartan, which belongs in the angiotensin-receptor blocking (ARB) drug class. It is a selective AT1 subtype angiotensin II receptor antagonist. Azilsartan medoxomil is a relatively recently-developed antihypertensive drug that was first approved by the FDA in February 2011. Many guidelines...
Approved
Investigational
Matched Iupac: … (5-methyl-2-oxo-2H-1,3-dioxol-4-yl)methyl 2-ethoxy-1-{[2'-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)-[1,1 …
Matched Categories: … Angiotensin 2 Receptor Blocker ... Heterocyclic Compounds, 2-Ring …
Matched Products: … AZEDOK 80 MG TABLET, 28 ADET ... AZEDOK 40 MG TABLET, 28 ADET …

Pantoprazole

Pantoprazole is a first-generation proton pump inhibitor (PPI) used for the management of gastroesophageal reflux disease (GERD), for gastric protection to prevent recurrence of stomach ulcers or gastric damage from chronic use of NSAIDs, and for the treatment of pathological hypersecretory conditions including Zollinger-Ellison (ZE) Syndrome. It can also be...
Approved
Matched Iupac: … 6-(difluoromethoxy)-2-[(3,4-dimethoxypyridin-2-yl)methanesulfinyl]-1H-1,3-benzodiazole …
Matched Salts cas: … 164579-32-2 …
Matched Categories: … 2-Pyridinylmethylsulfinylbenzimidazoles …
Matched Products: … STAMIC 40 MG ENTERIK TABLET, 28 ADET ... ABPAX 40 MG ENTERIK KAPLI TABLET, 28 ADET ... GASTRAZOL 40 MG ENTERİK TABLET, 28 ADET …

Fosinopril

Fosinopril is a phosphinic acid-containing ester prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is rapidly hydrolyzed to fosinoprilat, its principle active metabolite. Fosinoprilat inhibits ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). ATII regulates blood pressure and...
Approved
Matched Iupac: … -2-carboxylic acid ... (2S,4S)-4-cyclohexyl-1-(2-{[(1S)-2-methyl-1-(propanoyloxy)propoxy](4-phenylbutyl)phosphoryl}acetyl)pyrrolidine …
Matched Mixtures name: … MONOPRIL PLUS 10 MG/12.5 MG TABLET, 28 ADET ... MONOPRIL PLUS 20 MG/12.5 MG TABLET, 28 ADET …
Matched Products: … ACEFOR 10 MG TABLET, 28 ADET ... MONOPRIL 10 MG TABLET, 28 ADET ... MONOPRIL 20 MG TABLET, 28 ADET …

Erdafitinib

In early April of 2019, the US FDA approved Janssen Pharmaceutical Companies' brand name Balversa (erdafitinib) as the first-ever fibroblast growth factor receptor (FGFR) kinase inhibitor indicated for patients with locally advanced or metastatic urothelial carcinoma, with susceptible FGFR3 or FGFR2 genetic alterations, that has progressed during or following platinum-containing...
Approved
Investigational
Matched Iupac: … N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)-N-{2-[(propan-2-yl)amino]ethyl}quinoxalin-6-amine …
Matched Products: … BALVERSA 4 MG FİLM KAPLI TABLET, 28 ADET ... BALVERSA 5 MG FİLM KAPLI TABLET, 28 ADET …

Ezetimibe

Ezetimibe is a lipid-lowering compound that inhibits intestinal cholesterol and phytosterol absorption. The discovery and research of this drug began in the early 1990s, after the intravenous administration of radiolabelled ezetimibe in rats revealed that it was being localized within enterocytes of the intestinal villi - this prompted studies investigating...
Approved
Matched Iupac: … (3R,4S)-1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidin-2- …
Matched Mixtures name: … ROSALIN 10/5 MG TABLET, 28 ADET ... ROSALIN 10/10 MG TABLET, 28 ADET ... ROSALIN 10/20 MG TABLET, 28 ADET …
Matched Products: … KOLEZ 10 MG TABLET, 28 ADET ... EZETEC 10 MG TABLET, 28 ADET ... EZETROL 10 MG TABLET, 28 ADET …

Naltrexone

Derivative of noroxymorphone that is the N-cyclopropylmethyl congener of naloxone. It is a narcotic antagonist that is effective orally, longer lasting and more potent than naloxone, and has been proposed for the treatment of heroin addiction. The FDA has approved naltrexone for the treatment of alcohol dependence.
Approved
Investigational
Vet approved
Matched Salts cas: … 16676-29-2 …
Matched Products: … ETHYLEX 50 MG FILM TABLET, 28 ADET ... NOKREV 50 MG FİLM KAPLI TABLET, 28 ADET …

Urea

A compound formed in the liver from ammonia produced by the deamination of amino acids. It is the principal end product of protein catabolism and constitutes about one half of the total urinary solids.
Approved
Investigational
Matched Mixtures name: … Thomas Formula No 28 ... ROZA %1 + %2 KREM (30 G) ... Urea 39.5% with 2% Salicylic Acid …
Matched Products: … EXCİPİAL HYDRO % 2 EMÜLSİYON, 200 ML ... ELSPAR HYDRO %2 DERİYE UYGULANACAK EMÜLSİYON, 200 ML …

Anastrozole

Anastrozole is a non-steroidal aromatase inhibitor (AI), similar to letrozole, used to decrease circulating estrogen levels in the treatment of postmenopausal women with estrogen-responsive breast cancer. Anastrozole is also related to exemestane, a steroidal AI, but its non-steroidal nature provides stark advantages including a lack of steroid-associated adverse effects such...
Approved
Investigational
Matched Iupac: … 2-[3-(1-cyano-1-methylethyl)-5-[(1H-1,2,4-triazol-1-yl)methyl]phenyl]-2-methylpropanenitrile …
Matched Products: … SANTRA 1 MG TABLET, 28 ADET ... ANAZOL 1 MG FILM TABLET, 28 ADET ... VERIDEX 1 MG FILM TABLET, 28 ADET …

Levomefolic acid

Levomefolic acid (INN) is the metabolite of folic acid (Vitamin B9) and it is a predominant active form of folate found in foods and in the blood circulation, accounting for 98% of folates in human plasma . It is transported across the membranes including the blood-brain barrier into various tissues...
Approved
Investigational
Matched Synonyms: … N-[4-[[[(6S)-2-Amino-3,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl]methyl]amino]benzoyl]-L-glutamic …
Matched Iupac: … (2S)-2-{[4-({[(6S)-2-amino-5-methyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]formamido …
Matched Salts cas: … 1429498-11-2 …
Matched Mixtures name: … Tricare Prenatal 2-part Daily Prenatal Vitamin System …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Tibolone

Tibolone is a synthetic steroid hormone drug, which is mainly non-selective in its binding profile, acting as an agonist primarily at estrogen receptors (ER), with a preference for ER alpha . Tibolone (Livial, Org OD 14), produced by Organon (West Orange, NJ), is a synthetic steroid that possesses estrogenic, androgenic...
Approved
Investigational
Matched Iupac: … (1S,9R,10R,11S,14R,15S)-14-ethynyl-14-hydroxy-9,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadec-2(7) …
Matched Description: … It has been used in Europe for almost 2 decades, primarily for the prevention of postmenopausal osteoporosis …
Matched Products: … LADYBON 2.5 MG TABLET, 28 ADET ... LIVIAL 2.5 MG TABLET, 28 ADET …

Esomeprazole

Esomeprazole, sold under the brand name Nexium, is a proton pump inhibitor (PPI) medication used for the management of gastroesophageal reflux disease (GERD), for gastric protection to prevent recurrence of stomach ulcers or gastric damage from chronic use of NSAIDs, and for the treatment of pathological hypersecretory conditions including Zollinger-Ellison...
Approved
Investigational
Matched Iupac: … 5-methoxy-2-[(S)-(4-methoxy-3,5-dimethylpyridin-2-yl)methanesulfinyl]-1H-1,3-benzodiazole …
Matched Mixtures name: … ESOVIP 20/1680 MG TOZ İÇEREN SAŞE, 28 ADET …
Matched Categories: … 2-Pyridinylmethylsulfinylbenzimidazoles ... Heterocyclic Compounds, 2-Ring …
Matched Products: … ESOPRO 20MG KAPSÜL, 28 ADET ... ESOPRO 40 MG KAPSÜL,28 ADET ... ESOPRAL 40 MG KAPSÜL, 28 ADET …

Edoxaban

Edoxaban is a member of the Novel Oral Anti-Coagulants (NOACs) class of drugs, and is a rapidly acting, oral, selective factor Xa inhibitor. By inhibiting factor Xa, a key protein in the coagulation cascade, edoxaban prevents the stepwise amplification of protein factors needed to form blood clots. It is indicated...
Approved
Matched Iupac: … N'-(5-chloropyridin-2-yl)-N-[(1S,2R,4S)-4-(dimethylcarbamoyl)-2-{5-methyl-4H,5H,6H,7H-[1,3]thiazolo[5,4 ... -c]pyridine-2-amido}cyclohexyl]ethanediamide …
Matched Products: … LIXIANA 30 MG FILM KAPLI TABLET ,TABLET, 28 ADET ... LIXIANA 60 MG FILM KAPLI TABLET ,TABLET, 28 ADET …

Galantamine

Galantamine is a tertiary alkaloid and reversible, competitive inhibitor of the acetylcholinesterase (AChE) enzyme, which is a widely studied therapeutic target used in the treatment of Alzheimer's disease. First characterized in the early 1950s, galantamine is a tertiary alkaloid that was extracted from botanical sources, such as Galanthus nivalis. Galantamine...
Approved
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … BEKLAMEN 16 MG EFERVESAN TABLET, 28 ADET ... BEKLAMEN 24 MG EFERVESAN TABLET, 28 ADET ... BEKLAMEN 8 MG EFERVESAN TABLET, 28 ADET …

Metamfetamine

Metamfetamine (methamphetamine) is a psychostimulant and sympathomimetic drug, and a member of the amphetamine group of sympathomimetic amines. Methamphetamine can induce effects such as euphoria, increased alertness and energy, and enhanced self-esteem. It is a scheduled drug in most countries due to its high potential for addiction and abuse. The...
Approved
Illicit
Withdrawn
Matched Synonyms: … d-1-phenyl-2-methylaminopropane …
Matched Iupac: … methyl[(2S)-1-phenylpropan-2-yl]amine …
Matched Salts cas: … 62265-33-2 …
Matched Categories: … Adrenergic alpha-2 Receptor Agonists …

Gadopiclenol

Gadopiclenol is a gadolinium-based contrast agent (GBCA) based on a pyclen macrocyclic structure. It is indicated for use with magnetic resonance imaging (MRI) to detect and visualize lesions with abnormal vascularity in the central nervous system and the body. In 2006, the use of GBCAs was associated with the development...
Approved
Matched Synonyms: … 2-[3,9-bis[1-carboxylato-4-(2,3-dihydroxypropylamino)-4-oxobutyl]-3,6,9,15-tetrazabicyclo[9.3.1]pentadeca …
Matched Iupac: … gadolinium(3+) 2-[6,9-bis({1-carboxylato-3-[(2,3-dihydroxypropyl)carbamoyl]propyl})-3,6,9,15-tetraazabicyclo …

Levonorgestrel

Levonorgestrel (LNG) is a synthetic progestogen similar to Progesterone used in contraception and hormone therapy.[A181988,T659] Also known as Plan B, it is used as a single agent in emergency contraception, and as a hormonal contraceptive released from an intrauterine device, commonly referred to as an IUD. Some of these devices...
Approved
Investigational
Matched Mixtures name: … Aviane 28 Day ... Alesse 28 ... Esme 28 …
Matched Products: … Option 2 ... VALENOR 2 ... POSTINOR-2 …

Calcium glucoheptonate

Calcium supplements such as calcium gluceptate are taken by individuals who are unable to get enough calcium in their regular diet or who have a need for more calcium. They are used to prevent or treat several conditions that may cause hypocalcemia (not enough calcium in the blood). The body...
Approved
Matched Synonyms: … Calcium glucoheptonate (1:2) …

Ozanimod

Ozanimod is a once-daily sphingosine 1-phosphate receptor modulator for the treatment of relapsing Multiple Sclerosis (MS) and inflammatory bowel disease. It was developed by Celgene (now acquired by Bristol-Myers Squibb) and was approved by the FDA on March 26, 2020.[L12573,L12582] The US approval was followed by the approval in Canada...
Approved
Investigational
Matched Iupac: … 5-{3-[(1S)-1-[(2-hydroxyethyl)amino]-2,3-dihydro-1H-inden-4-yl]-1,2,4-oxadiazol-5-yl}-2-(propan-2-yloxy …
Matched Description: … [L12573,L12582] The US approval was followed by the approval in Canada on October 2, 2020. …
Matched Products: … ZEPOSİA 0,92 MG SERT KAPSÜL, 28 ADET …

Secobarbital

Secobarbital (marketed by Eli Lilly and Company under the brand names Seconal and Tuinal) is a barbiturate derivative drug with anaesthetic, anticonvulsant, sedative and hypnotic properties. It is commonly known as quinalbarbitone in the United Kingdom.
Approved
Vet approved
Matched Synonyms: … 5-(1-methylbutyl)-5-(2-propenyl)-2,4,6(1H,3H,5H)-pyrimidinetrione …
Matched Iupac: … 5-(pentan-2-yl)-5-(prop-2-en-1-yl)-1,3-diazinane-2,4,6-trione …

Cyproterone acetate

An anti-androgen that, in the form of its acetate (cyproterone acetate), also has progestational properties. It is used in the treatment of hypersexuality in males, as a palliative in prostatic carcinoma, and, in combination with estrogen, for the therapy of severe acne and hirsutism in females.
Approved
Investigational
Matched Mixtures name: … พรีม 28 ... ซูซี่ 28 ... ไซโปรเน่ 28 …

Salmon calcitonin

Synthetic peptide, 32 residues long formulated as a nasal spray.
Approved
Investigational
Matched Products: … TONOCALCIN 200 IU 28 DOZ NAZAL SPREY ... TONOCALCIN 3.5 ML 100IU 28 DOZ NAZAL SPREY …

Imdevimab

Imdevimab is a monoclonal antibody combined with casirivimab in Regeneron's antibody cocktail known as REGEN-COV2 for the treatment of COVID-19. This drug is a combination of antibodies derived from humanized VelocImmune® mice in addition to blood samples from patients who have recovered from COVID-19. These antibodies have been formulated to...
Approved
Experimental
Matched Description: … [A224429] These antibodies have been formulated to bind to multiple locations on the SARS-COV-2 spike …

Eltrombopag

Eltrombopag is used to treat low blood platelet counts in adults with chronic immune (idiopathic) thrombocytopenia (ITP), when certain other medicines, or surgery to remove the spleen, have not worked well enough. ITP is a condition that may cause unusual bruising or bleeding due to an abnormally low number of...
Approved
Matched Iupac: … 3'-{2-[(4Z)-1-(3,4-dimethylphenyl)-3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-4-ylidene]hydrazin-1-yl}-2'- …
Matched Products: … ROMPAG 25 MG FİLM KAPLI TABLET, 28 ADET ... ROMPAG 50 MG FİLM KAPLI TABLET, 28 ADET …
Displaying drugs 276 - 300 of 11645 in total