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Displaying drugs 276 - 300 of 6149 in total

DCLL-9718S

DCLL9718S is an antibody-drug conjugate targeting C-type lectin-like molecule-1 (CLL-1). DCLL9718S is under investigation in clinical trial NCT03298516 (A Study of DCLL9718S in Participants With Relapsed or Refractory Acute Myeloid Leukemia (AML) or DCLL9718S in Combination With Azacitidine in Participants With Previously Untreated AML Unsuitable for Intensive Induction Chemotherapy).
Investigational
Matched Synonyms: … antibody and DNA alkylating cross-linking agent pyrrolo [2,1-c][1,4] benzodiazepine dimer ... THIOMAB antibody drug conjugate comprised of humanized IgG1 anti-C-type lectin-like molecule-1 monoclonal …
Matched Description: … DCLL9718S is an antibody-drug conjugate targeting C-type lectin-like molecule-1 (CLL-1). …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Pyrethrum extract

Pyrethrum is the crude extract form obtained from flowers of the plant Chrysanthemum cinerariifolium. Pyrethrin refers to a more refined extract of pyrethrum. While pyrethrum extract is composed of 6 esters, both organic compounds mediate insecticidal activities. Pyrethrum-containing mixtures are used as a common insecticide to control specific pest species....
Approved
Matched Synonyms: … Pyrethrins and pyrethroids …
Matched Description: … is thought to exert minimal effect on humans. ... Pyrethrum extract is also used used to treat head, body, and pubic lice infections. ... The active compound is absorbed by the lice and destroys them by acting on their nervous systems but …
Matched Mixtures name: … Lice-Nil Lice and Eggs Killer ... Medi and Lice Lice Killing ... Weeks and Leo Complete Lice Treatment …

Calcium carbonate

Calcium carbonate is an inorganic salt used as an antacid. It is a basic compound that acts by neutralizing hydrochloric acid in gastric secretions. Subsequent increases in pH may inhibit the action of pepsin. An increase in bicarbonate ions and prostaglandins may also confer cytoprotective effects. Calcium carbonate may also...
Approved
Investigational
Matched Synonyms: … Calcium carbonate (1:1) ... Carbonic acid calcium salt (1:1) …
Matched Description: … An increase in bicarbonate ions and prostaglandins may also confer cytoprotective effects. …
Matched Mixtures name: … PNV Tabs 29-1 ... PNV Tabs 29-1 ... PNV Tabs 20-1 …
Matched Categories: … Alimentary Tract and Metabolism ... Antacids and Adsorbents ... ascorbic acid (vit C) and calcium …
Matched Products: … Alka-Seltzer Heartburn ReliefChews Strawberry and Orange ... HEB Lime and Berry Antacid Chews ... up and up extra strength smooth dissolving antacid Assorted Fruit …

Trolamine salicylate

Trolamine salicylate is an organic compound or a salt formed between triethanolamine and salicylic acid. Triethanolamine neutralizes the acidity of the salicylic acid. It is a topical analgesic used for temporary relief of minor pain associated with arthritis, simple backache, muscle strains, sprains, and bruises. Unlike other topical analgesics, trolamine...
Approved
Matched Iupac: … 2-[bis(2-hydroxyethyl)amino]ethan-1-ol; 2-hydroxybenzoic acid …
Matched Description: … Trolamine salicylate is an organic compound or a salt formed between triethanolamine and salicylic acid ... temporary relief of minor pain associated with arthritis, simple backache, muscle strains, sprains, and ... It also displays low systemic absorption upon dermal or topical administration [A32190] and has low skin …
Matched Mixtures name: … ELF Flawless Finish Foundation SPF 15 Oil Free …
Matched Categories: … Non COX-2 selective NSAIDS …
Matched Products: … Up and Up Pain Relief Odorless ... Up and Up Odor-free Pain Relieving Cream ... Blue-Emu Ultra with Hemp Seed …

Xylometazoline

Xylometazoline is an imidazoline derivative with sympathomimetic and nasal decongestant activity. Xylometazoline works by binding to alpha (α)-adrenergic receptors to cause vasoconstriction of nasal blood vessels. Xylometazoline is available in over-the-counter (OTC) nasal sprays or drops to temporarily relieve nasal congestion due to cold, hay fever or other respiratory allergies....
Approved
Investigational
Matched Iupac: … 2-[(4-tert-butyl-2,6-dimethylphenyl)methyl]-4,5-dihydro-1H-imidazole …
Matched Description: … Xylometazoline is an imidazoline derivative [A228523] with sympathomimetic and nasal decongestant activity …
Matched Mixtures name: … NASOWELL 1 MG/ML+ 50 MG/ML BURUN SPREYİ, ÇÖZELTİ, 1 ADET ... nasic - Nasenspray 10 mg/500 mg ... ratioSoft plus Dexpanthenol 1,0 mg/50 mg/ml Nasenspray …
Matched Categories: … Decongestants and Antiallergics ... Adrenergic alpha-2 Receptor Agonists ... Adrenergic alpha-1 Receptor Agonists ... Heterocyclic Compounds, 1-Ring …
Matched Products: … Cold and Allergy Decongestant Nasal Spray ... Otrivin Cold and Allergy Decongestant Nose Drops ... Otrivin Allergy and Cold Decongestant Nasal Spray …

Garcinia gummi-gutta fruit

Garcinia gummi-gutta fruit is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Experimental
Matched Synonyms: … Garcinia Cambogia (Constituent of Garcinia Cambogia and Garcinia Indica) …

Tetryzoline

Tetryzoline, also known as tetrahydrozoline, is a derivative of imidazoline with central and peripheral alpha (α)-adrenergic properties. Available since the 1950s, tetryzoline is a selective α1-receptor agonist that is used as an ocular and nasal decongestant. Tetryzoline is found in a wide array of over-the-counter eye drops, including the most...
Approved
Matched Synonyms: … 2-(1,2,3,4-Tetrahydro-1-naphthyl)-2-imidazoline ... 2-Tetralin-1-yl-4,5-dihydro-1H-imidazole ... (RS)-2-(1,2,3,4-tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazole …
Matched Iupac: … 2-(1,2,3,4-tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazole …
Matched Description: … [A231769] Available since the 1950s, tetryzoline is a selective α1-receptor agonist [A231774 ... Tetryzoline, also known as tetrahydrozoline, is a derivative of imidazoline with central and peripheral ... ] that is used as an ocular and nasal decongestant. …
Matched Mixtures name: … Redness reliever and Lubricant ... Seasonal itchy and Red eye relief ... Up and Up Ultra Itchy Relief …
Matched Categories: … Decongestants and Antiallergics ... Adrenergic alpha-1 Receptor Agonists ... Heterocyclic Compounds, 1-Ring …
Matched Products: … Walgreens Eye Drops Original 15mL and twin pack ... Foster and Thrive Original Formula Eye Drops ... Murine Plus 2 …

Orvacabtagene autoleucel

Investigational
Matched Synonyms: … CD4+ CD8+ T CELLS ARE DERIVED FROM ISOLATED BLOOD OF THE PATIENT AND ARE TRANSDUCED WITH NON-REPLICATIVE ... JCARH125 CONSISTS OF HUMAN CULTURE EXPANDED GENETICALLY MODIFIED AUTOLOGOUS T CELLS FOR CELL-BASED GENE …

Relmacabtagene autoleucel

Investigational
Matched Synonyms: … AUTOLOGOUS CD4+ AND CD8+ T CELLS, ENRICHED FROM PERIPHERAL BLOOD MONONUCLEAR CELLS (PBMCS) TRANSDUCED ... SELF-INACTIVATING (SIN) LENTIVIRAL VECTOR ENCODING A CHIMERIC ANTIGEN RECEPTOR (CAR) CONSISTING OF THE HUMAN …

Bisacodyl

Bisacodyl, a diphenylmethane derivative, is a commonly used over the counter stimulant laxative for occasional constipation.[A233300,L13362] Both bisacodyl and picosulfate are metabolized to the same active metabolite bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM).[A233290,A233300,A207700] Bisacodyl was patented on 25 September 1956 but has been used as a laxative since 1952.
Approved
Matched Synonyms: … Phenol, 4,4'-(2-pyridinylmethylene)bis-, diacetate (ester) …
Matched Iupac: … 4-{[4-(acetyloxy)phenyl](pyridin-2-yl)methyl}phenyl acetate …
Matched Description: … [A233300,L13362] Both bisacodyl and [picosulfate] are metabolized to the same active metabolite bis-( ... p-hydroxyphenyl)-pyridyl-2-methane (BHPM). ... [A233290,A233300,A207700] Bisacodyl was patented on 25 September 1956[L33045] but has been used as …
Matched Mixtures name: … PCP 100 Kit ... HalfLytely and Bisacodyl ... HalfLytely and Bisacodyl …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Up and Up womens laxative ... Up and Up Gentle Laxative ... Gentle and Effective Laxative Enteric Coated …

Tefidsogene civaparvovec

Tefidsogene civaparvovec, formerly known as SB-913, is an investigational therapy for genome editing. It consists of an adeno-associated virus (AAV) type 2/6 vector and a zinc finger nuclease (ZFN) system that inserts a correct copy of the Iduronate 2-Sulfatase (IDS) gene into the albumin locus in hepatocytes. Developed by Sangamo...
Experimental
Matched Synonyms: … A PROMOTER-LESS HUMAN IDURONATE 2-SULFATASE (HIDS) TRANSGENE CASSETTE, ENCODING PARTS OF EXON 1 PLUS ... EXONS 2-9 FROM HIDS AND A SPLICE ACCEPTOR SITE (SA) ... A RECOMBINANT NON-REPLICATING ADENO-ASSOCIATED VIRUS TYPE 2/6 (RAAV REP2-CAP6) VECTOR, WHICH CONTAINS …
Matched Description: … It consists of an adeno-associated virus (AAV) type 2/6 vector and a zinc finger nuclease (ZFN) system ... that inserts a correct copy of the Iduronate 2-Sulfatase (IDS) gene into the albumin locus in hepatocytes …

Vanglusagene ensiparvovec

Investigational
Matched Synonyms: … recombinant adeno-associated viral (AAV) vector that contains a bio-engineered capsid (AAV-Spark100) and ... a codon-optimized expression cassette to drive expression of a secretable form of human acid a-glucosidase …

Somatotropin

Human growth hormone (HGH), also known as somatotropin, is a peptide hormone that is synthesized and secreted by the somatotropic cells of the anterior pituitary gland. Growth hormone plays an essential role in growth regulation during childhood as well as other basal metabolic functions, muscle and fat mass regulation, blood...
Approved
Investigational
Matched Synonyms: … Growth hormone (human) ... Human growth hormone ... Somatotropin human …
Matched Description: … Human growth hormone (HGH), also known as somatotropin, is a peptide hormone that is synthesized and ... It has an identical primary protein structure to endogenous human growth hormone. ... amino acid residues with a molecular weight of 22 kDa. …
Matched Categories: … Recombinant Human Growth Hormone ... Human Growth Hormone, antagonists & inhibitors ... Amino Acids, Peptides, and Proteins ... Anterior Pituitary Lobe Hormones and Analogues ... Pituitary and Hypothalamic Hormones and Analogues …
Matched Products: … ZOMACTON Powder and Solvent for Solution for Injection 10mg ... ZOMACTON Powder and Solvent for Solution for Injection 4 mg ... GENOTROPIN® 12MG POWDER AND SOLVENT FOR SOLUTION FOR INJECTION …

Lanolin

Lanolin is a yellow fat obtained from sheep's wool. It is used as an emollient, cosmetic, and pharmaceutic aid . The US federal code of regulations states that lanolin in the concentration range of 12-50% may be included in over the counter skin ointments . Lanolin is the purified, secreted...
Approved
Matched Synonyms: … Wool wax, lanolin ... Wool wax, refined …
Matched Description: … Lanolin is used in the protection, treatment, and cosmetic enhancement of human skin. ... It is used as an emollient, cosmetic, and pharmaceutic aid [L2580]. ... as an active ingredient in over the counter topical products such as ointments, lubricants, lotions and …
Matched Mixtures name: … Vitamins A and D Diaper Rash ... PETROLATUM and LANOLIN ... Blistex Revive and Restore …
Matched Categories: … Basic Ointments and Protectants ... Waxes …
Matched Products: … Soothe and Cool Free Medseptic Skin Protectant …

Thiotepa

N,N'N'-triethylenethiophosphoramide (ThioTEPA) is a cancer chemotherapeutic member of the alkylating agent group, now in use for over 50 years. It is a stable derivative of N,N',N''- triethylenephosphoramide (TEPA). It is mostly used to treat breast cancer, ovarian cancer and bladder cancer. It is also used as conditioning for Bone marrow...
Approved
Investigational
Matched Iupac: … tris(aziridin-1-yl)-lambda5-phosphanethione …
Matched Description: … It is mostly used to treat breast cancer, ovarian cancer and bladder cancer. …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Heterocyclic Compounds, 1-Ring …
Matched Products: … TEPADINA 400 mg powder and solvent for solution for infusion ... THIO SPAL-P 100 ... Thiotepa - (pws 15 Mg/vial) …

Echinacea angustifolia root

Approved
Experimental
Matched Synonyms: … Echinacea angustifolia root ... Echinacea angustifolia root extract ... Echinaceae angustifoliae radix …
Matched Name: … Echinacea angustifolia root …

Levomenthol

Menthol is a covalent organic compound made synthetically or obtained from peppermint or other mint oils. Forming clear or white waxy, crystalline substance, menthol is typically solid at room temperature. (-)-Menthol is the naturally-occurring and main form of menthol, and is assigned the (1R,2S,5R) configuration. Menthol mediates anesthetic properties and...
Approved
Matched Synonyms: … (1R-(1-α,2-β,5-α))-5-methyl-2-(1-methylethyl)cyclohexanol ... (1alpha,2beta,5alpha)-5-methyl-2(1-methylethyl)cyclohexanol ... (−)-(1R,3R,4S)-menthol …
Matched Iupac: … (1R,2S,5R)-5-methyl-2-(propan-2-yl)cyclohexan-1-ol …
Matched Description: … -)-Menthol is the naturally-occurring and main form of menthol, and is assigned the (1R,2S,5R) configuration ... Forming clear or white waxy, crystalline substance, menthol is typically solid at room temperature. ( ... Menthol mediates anesthetic properties and anti-irritating properties locally, thus it is widely used …
Matched Mixtures name: … GLYCERIN OF THYMOL ... Multi-action Denorex 2-IN-1 Dandruff Shampoo + Conditioner ... SEE FULL OIL …
Matched Categories: … Antipruritics and Local Anesthetics ... Basic Lotions and Liniments ... Herbs and Natural Products ... Other Cold and Cough Preparations …
Matched Products: … Sport Cold - Gel - 2% ... Musle and Joint ... Performance and Recovery …

Pectin

Pectin is a heteropolysaccharide commercially derived from the cell wall of higher plants. It is composed of partially methylated polygalacturonic acid units linked in the positions 1-4. The carboxylic group of the constituents of pectin can exist in the form of esters, free acids, ammonium, potassium or sodium salts or...
Approved
Investigational
Vet approved
Matched Description: … [A32327] It is composed of partially methylated polygalacturonic acid units linked in the positions 1- …
Matched Mixtures name: … Kaolin and Pectin Susp ... Cepacol Sore Throat and Coating ... Sucrets Complete Sore Throat, Cough and Irritation …
Matched Categories: … Alimentary Tract and Metabolism ... Diet, Food, and Nutrition …
Matched Products: … Ludens Honey and Berry ... Lolleez Variety Pack 21 ... Throat Coat Lemon Ginger Echinacea …

Insulin aspart

Insulin aspart is a rapid-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the...
Approved
Matched Synonyms: … Insulin, aspart, human ... Insulin, aspart protamine, human …
Matched Description: … and Type 2 Diabetes. ... typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human ... Compared to human insulin, it has a single amino acid substitution at position B28 where proline is replaced …
Matched Mixtures name: … RYZODEG FLEXTOUCH 100 U/ML ENJEKSİYONLUK ÇOZELTİ İÇEREN KULLANIMA HAZIR KALEM, 2 ADET ... RYZODEG PENFİLL 100 U/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KARTUŞ, 10 ADET ... RYZODEG 100 UNIDADES/ML …
Matched Categories: … Alimentary Tract and Metabolism ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists ... insulin degludec and insulin aspart ... Insulins and Analogues for Injection, Fast-Acting …
Matched Products: … Insulin Aspart Protamine and Insulin Aspart Mix 70/30 ... .Insulin Aspart Protamine and Insulin Aspart ... 100 U/ML …

Beroctocog alfa

Approved
Investigational
Matched Mixtures name: … ALPHANATE FOR INJECTION 250 iu/vial …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Human Antihemophilic Factors …
Matched Products: … Humate-P ... อิมมูเนต 250 ไอยู ... FACTOR VIII DE COAGULACION HUMANO 500 UI …

Nogapendekin alfa

Nogapendekin alfa is a human IL-15N72D variant. It is one of the active ingredients in Anktiva, a combination product also containing inbakicept, where a single inbakicept is complexed with two nogapendekin alfa components. This combination product was approved by the FDA on April 22, 2024, for the treatment of BCG-unresponsive...
Approved
Investigational
Matched Synonyms: … Human interleukin 15 (72-aspartic acid) (human il-15 n72>d isoform) ... Fusion protein consisting of il-15n72d and il-15rasu/fc ... Superagonist interleukin-15:interleukin-15 receptor alphasu/fc fusion complex alt-803 …
Matched Description: … Nogapendekin alfa is a human IL-15N72D variant. ... stimulating the activation and proliferation of natural killer cells and CD8+ memory T cells, which also ... 75% of all bladder tumours, is commonly treated with transurethral resection of the bladder tumour and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Receptors, Interleukin-15 …

Aluminum zirconium tetrachlorohydrex gly

Aluminum zirconium tetrachlorohydrex gly is a common active ingredient in personal care products as an antiperspirant agent. Its main mechanism of action is through blocking the pores via formation of polymer complex and preventing sweat from leaving the body.
Approved
Matched Description: … Its main mechanism of action is through blocking the pores via formation of polymer complex and preventing …
Matched Products: … Ap 22% (regular,sport,musk and Unscented) ... Mitchum Clear Gel A.P. and Deod.supersport ... Body Satin Antiperspirant and Deodorant …

Hypochlorous acid

An oxyacid of chlorine (HClO) containing monovalent chlorine that acts as an oxidizing or reducing agent.
Experimental
Matched Mixtures name: … K-100 ... K-100 ... Orak-100 …
Matched Products: … Tok and Care Sanitizer ... Dfenze HOCL Sanitizer and Disinfectant …

Mucor circinelloides f. lusitanicus

Mucor circinelloides f. lusitanicus allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Molds, rusts and smuts, mucor circinelloides f. lusitanicus …

Ivermectin

Ivermectin is a semi-synthetic antiparasitic medication derived from avermectins, a class of highly-active broad-spectrum antiparasitic agents isolated from the fermentation products of Streptomyces avermitilis. Ivermectin itself is a mixture of two avermectins, comprising roughly 90% 5-O-demethyl-22,23-dihydroavermectin A1a (22,23-dihydroavermectin B1a) and 10% 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro­-25-(1-methylethyl)avermectin A1a (22,23-dihydroavermectin B1b). Ivermectin is mainly used in...
Approved
Investigational
Vet approved
Matched Iupac: … (1'R,2R,4'S,5S,6R,8'R,10'E,12'S,13'S,14'E,16'E,20'R,21'R,24'S)-21',24'-dihydroxy-12'-{[(2R,4S,5S,6S)- ... }]pentacosane]-10',14',16',22'-tetraen-2'-one; (1'R,2R,4'S,5S,6R,8'R,10'E,12'S,13'S,14'E,16'E,20'R,21 ... [oxane-2,6'-tetracyclo[15.6.1.1^{4,8}.0^{20,24}]pentacosane]-10',14',16',22'-tetraen-2'-one ... -6-methyloxan-2-yl]oxy}-4-methoxy-6-methyloxan-2-yl]oxy}-5,11',13',22'-tetramethyl-3',7',19'-trioxaspiro ... 'R,24'S)-6-[(2S)-butan-2-yl]-21',24'-dihydroxy-12'-{[(2R,4S,5S,6S)-5-{[(2S,4S,5S,6S)-5-hydroxy-4-methoxy …
Matched Description: … (22,23-dihydroavermectin B1a) and 10% 5-O-demethyl-25-de(1-methylpropyl)-22,23-dihydro ... for COVID-19 in humans becomes available, the use of ivermectin for these purposes should be avoided ... ­-25-(1-methylethyl)avermectin A1a (22,23-dihydroavermectin B1b). …
Matched Mixtures name: … Heartgard Plus Chewable Tablet for Dogs - 26 - 50 lbs ... Heartgard Plus Chewable Tablet for Dogs - Up to 25 lbs ... Ivermectin 1% / Metronidazole 1% …
Matched Categories: … Antiparasitic Products, Insecticides and Repellents ... Scabicides and Pediculicides …
Matched Products: … IVOMEC Injection 1% w/v for Cattle and Sheep ... Neck Hump Removal Patch ... ZİVER 3 MG TABLET, 20 ADET …
Displaying drugs 276 - 300 of 6149 in total