Displaying drugs 276 - 300 of 13578 in total
Niraparib
Niraparib is an orally active poly (ADP-ribose) polymerase (PARP) inhibitor. By blocking the enzymes responsible for DNA repair, niraparib induces cytotoxicity in cancer cells. Niraparib is selective towards PARP-1 and PARP-2. First approved by the FDA on March 27, 2017, niraparib is used to treat epithelial ovarian, fallopian tube, or...
Approved
Investigational
Matched Iupac: … 2-{4-[(3S)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide …
Matched Description: … [L43277] Niraparib is selective towards PARP-1 and PARP-2. ... [L43277] Niraparib was approved by the European Commission on November 16, 2017 [L43742] and by Health …
Matched Categories: … MATE 1 Substrates with a Narrow Therapeutic Index ... MATE 2 Substrates with a Narrow Therapeutic Index ... MATE 1 Inhibitors ... MATE 1 Substrates ... MATE 2 Inhibitors …
Matched Description: … [L43277] Niraparib is selective towards PARP-1 and PARP-2. ... [L43277] Niraparib was approved by the European Commission on November 16, 2017 [L43742] and by Health …
Matched Categories: … MATE 1 Substrates with a Narrow Therapeutic Index ... MATE 2 Substrates with a Narrow Therapeutic Index ... MATE 1 Inhibitors ... MATE 1 Substrates ... MATE 2 Inhibitors …
Nintedanib
Nintedanib is a small molecule kinase inhibitor used in the treatment of pulmonary fibrosis, systemic sclerosis-associated interstitial lung disease, and non-small cell lung cancer (NSCLC).[L8453,L8459] It was first approved for use in the United States in 2014. Within the spectrum of idiopathic pulmonary fibrosis treatment options, nintedanib is currently one...
Approved
Matched Synonyms: … methyl (3Z)-3-[(4-{methyl[(4-methylpiperazin-1-yl)acetyl]amino}anilino)(phenyl)methylidene]-2-oxo-2,3 …
Matched Iupac: … methyl (3Z)-3-[({4-[N-methyl-2-(4-methylpiperazin-1-yl)acetamido]phenyl}amino)(phenyl)methylidene]-2- …
Matched Description: … Nintedanib is a small molecule kinase inhibitor used in the treatment of pulmonary fibrosis, systemic ... [A185237] As a chemotherapeutic agent for NSCLC, nintedanib, in combination with [Docetaxel], is reserved ... therapies available and indicated for the condition (the other being [Pirfenidone]) and as such is used as a …
Matched Iupac: … methyl (3Z)-3-[({4-[N-methyl-2-(4-methylpiperazin-1-yl)acetamido]phenyl}amino)(phenyl)methylidene]-2- …
Matched Description: … Nintedanib is a small molecule kinase inhibitor used in the treatment of pulmonary fibrosis, systemic ... [A185237] As a chemotherapeutic agent for NSCLC, nintedanib, in combination with [Docetaxel], is reserved ... therapies available and indicated for the condition (the other being [Pirfenidone]) and as such is used as a …
Saxagliptin
Saxagliptin (rINN) is an orally active hypoglycemic (anti-diabetic drug) of the new dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. FDA approved on July 31, 2009.
Approved
Matched Synonyms: … (1S,3S,5S)-2-((2S)-Amino(3-hydroxytricyclo(3.3.1.13,7)dec-1-yl)acetyl)-2-azabicyclo(3.1.0)hexane-3-carbonitrile …
Matched Iupac: … (1S,3S,5S)-2-[(2S)-2-amino-2-(3-hydroxyadamantan-1-yl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile …
Matched Description: … FDA approved on July 31, 2009. …
Matched Salts cas: … 945667-22-1 ... 1073057-20-1 …
Matched Iupac: … (1S,3S,5S)-2-[(2S)-2-amino-2-(3-hydroxyadamantan-1-yl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile …
Matched Description: … FDA approved on July 31, 2009. …
Matched Salts cas: … 945667-22-1 ... 1073057-20-1 …
Histrelin
Histrelin is a gonadotropin-releasing hormone (GnRH) agonist that acts as a potent inhibitor of gonadotropin when administered as an implant delivering continuous therapeutic doses. This drug is a synthetic analog of naturally occurring GnRH with a higher potency. Histrelin implants are non-biodegradable, diffusion-controlled, hydrogel polymer reservoirs containing histrelin acetate that...
Approved
Withdrawn
Matched Synonyms: … 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-1-benzyl-D-histidyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide ... 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-Nτ-benzyl-D-histidyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide …
Matched Iupac: … (2S)-1-[(2S)-2-[(2S)-2-[(2R)-3-(1-benzyl-1H-imidazol-4-yl)-2-[(2S)-2-[(2S)-3-hydroxy-2-[(2S)-2-[(2S)- ... ]-N-ethylpyrrolidine-2-carboxamide; bis(acetic acid) ... 3-(1H-imidazol-4-yl)-2-{[(2S)-5-oxopyrrolidin-2-yl]formamido}propanamido]-3-(1H-indol-3-yl)propanamido ... ]propanamido]-3-(4-hydroxyphenyl)propanamido]propanamido]-4-methylpentanamido]-5-carbamimidamidopentanoyl …
Matched Description: … This drug is a synthetic analog of naturally occurring GnRH with a higher potency. ... Histrelin is a gonadotropin-releasing hormone (GnRH) agonist that acts as a potent inhibitor of gonadotropin …
Matched Iupac: … (2S)-1-[(2S)-2-[(2S)-2-[(2R)-3-(1-benzyl-1H-imidazol-4-yl)-2-[(2S)-2-[(2S)-3-hydroxy-2-[(2S)-2-[(2S)- ... ]-N-ethylpyrrolidine-2-carboxamide; bis(acetic acid) ... 3-(1H-imidazol-4-yl)-2-{[(2S)-5-oxopyrrolidin-2-yl]formamido}propanamido]-3-(1H-indol-3-yl)propanamido ... ]propanamido]-3-(4-hydroxyphenyl)propanamido]propanamido]-4-methylpentanamido]-5-carbamimidamidopentanoyl …
Matched Description: … This drug is a synthetic analog of naturally occurring GnRH with a higher potency. ... Histrelin is a gonadotropin-releasing hormone (GnRH) agonist that acts as a potent inhibitor of gonadotropin …
Nifedipine
Nifedipine, or BAY a 1040, is a first generation dihydropyridine L-type calcium channel blocker, similar to nicardipine.[A190210,A190273,A175390,L11383] Nifedipine was developed by Bayer and first described in the literature, along with other dihydropyridines, in 1972.[A175390,A190276] Since nifedipine's development, second and third generation dihydropyridines have been developed with slower onsets and longer...
Approved
Matched Synonyms: … 4-(2'-Nitrophenyl)-2,6-dimethyl-1,4-dihydropyridin-3,5-dicarbonsäuredimethylester …
Matched Iupac: … 3,5-dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate …
Matched Description: … Nifedipine, or BAY a 1040, is a first generation dihydropyridine L-type calcium channel blocker, similar …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … ANHITEN-A …
Matched Iupac: … 3,5-dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate …
Matched Description: … Nifedipine, or BAY a 1040, is a first generation dihydropyridine L-type calcium channel blocker, similar …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … ANHITEN-A …
Bendamustine
Bendamustine is a nitrogen mustard drug which has been used in the treatment of chronic lymphocytic leukemia (CLL) and indolent B-cell non-Hodgkin lymphoma (NHL). Bendamustine is a bifunctional mechlorethamine derivative capable of forming electrophilic alkyl groups that covalently bond to other molecules. Through this function as an alkylating agent, bendamustine...
Approved
Investigational
Matched Iupac: … 4-{5-[bis(2-chloroethyl)amino]-1-methyl-1H-1,3-benzodiazol-2-yl}butanoic acid …
Matched Description: … (CLL) and indolent B-cell non-Hodgkin lymphoma (NHL). ... Bendamustine is a nitrogen mustard drug which has been used in the treatment of chronic lymphocytic leukemia ... Bendamustine is a bifunctional mechlorethamine derivative capable of forming electrophilic alkyl groups …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index …
Matched Products: … GENSTINA® POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE ... INFÜZYON IÇIN LIYOFILIZE TOZ IÇEREN FLAKON ,1 ADET ... INFÜZYON IÇIN LIYOFILIZE TOZ IÇEREN FLAKON ,1 ADET …
Matched Description: … (CLL) and indolent B-cell non-Hodgkin lymphoma (NHL). ... Bendamustine is a nitrogen mustard drug which has been used in the treatment of chronic lymphocytic leukemia ... Bendamustine is a bifunctional mechlorethamine derivative capable of forming electrophilic alkyl groups …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index …
Matched Products: … GENSTINA® POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE ... INFÜZYON IÇIN LIYOFILIZE TOZ IÇEREN FLAKON ,1 ADET ... INFÜZYON IÇIN LIYOFILIZE TOZ IÇEREN FLAKON ,1 ADET …
Ropivacaine
Ropivacaine is an aminoamide local anesthetic drug marketed by AstraZeneca under the trade name Naropin. It exists as a racemate of its S- and R-enantiomers, although the marketed form is supplied only as the purified S-enantiomer.
Approved
Matched Synonyms: … (S)-(−)-1-propyl-2',6'-pipecoloxylidide ... L-N-n-propylpipecolic acid-2,6-xylidide …
Matched Iupac: … (2S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide …
Matched Description: … It exists as a racemate of its S- and R-enantiomers, although the marketed form is supplied only as the …
Matched Products: … NAROPIN INJECTION 1% ... Ropivacain-HCl B. Braun 2 mg/ml Injektions-/ Infusionslösung ... ROPIVACAINE-AFT SOLUTION FOR INJECTION 1% W/V …
Matched Iupac: … (2S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide …
Matched Description: … It exists as a racemate of its S- and R-enantiomers, although the marketed form is supplied only as the …
Matched Products: … NAROPIN INJECTION 1% ... Ropivacain-HCl B. Braun 2 mg/ml Injektions-/ Infusionslösung ... ROPIVACAINE-AFT SOLUTION FOR INJECTION 1% W/V …
Ergocalciferol
Ergocalciferol is an inactivated vitamin D analog. It is synthesized by some plants in the presence of UVB light. The production of ergocalciferol was prompted by the identification of dietary deficiency, more specifically vitamin D, as the main causative factor for the development of rickets. Ergocalciferol was isolated for the...
Approved
Nutraceutical
Matched Synonyms: … Vitamin D-2 ... (3β,5Z,7E,22E)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol ... (5Z,7E,22E)-(3S)-9,10-seco-5,7,10(19),22-ergostatetraen-3-ol …
Matched Iupac: … (1S,3Z)-3-{2-[(1R,3aS,4E,7aR)-1-[(2R,3E,5R)-5,6-dimethylhept-3-en-2-yl]-7a-methyl-octahydro-1H-inden- ... 4-ylidene]ethylidene}-4-methylidenecyclohexan-1-ol …
Matched Description: … Ergocalciferol is an inactivated vitamin D analog. ... double bond between C22 and C23 and the presence of a methyl group at C24. ... considered the first vitamin D analog and is differentiated from [cholecalciferol] by the presence of a …
Matched Mixtures name: … Cal/mag 2:1 With D ... Calcium Magnesium 2:1 Tablets With Vitamin D ... Mvc 9 Plus 3 Inj …
Matched Iupac: … (1S,3Z)-3-{2-[(1R,3aS,4E,7aR)-1-[(2R,3E,5R)-5,6-dimethylhept-3-en-2-yl]-7a-methyl-octahydro-1H-inden- ... 4-ylidene]ethylidene}-4-methylidenecyclohexan-1-ol …
Matched Description: … Ergocalciferol is an inactivated vitamin D analog. ... double bond between C22 and C23 and the presence of a methyl group at C24. ... considered the first vitamin D analog and is differentiated from [cholecalciferol] by the presence of a …
Matched Mixtures name: … Cal/mag 2:1 With D ... Calcium Magnesium 2:1 Tablets With Vitamin D ... Mvc 9 Plus 3 Inj …
Osimertinib
Osimertinib is an oral, third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) drug developed by AstraZeneca Pharmaceuticals.[A7926,L43453] Its use is indicated for the treatment of metastatic non-small cell lung cancer (NSCLC) in cases where tumour EGFR expression is positive for the T790M mutation as detected by FDA-approved testing...
Approved
Matched Synonyms: … N-(2-{[2-(dimethylamino)ethyl](methyl)amino}-4-methoxy-5-{[4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl]amino ... }phenyl)prop-2-enamide …
Matched Iupac: … N-(2-{[2-(dimethylamino)ethyl](methyl)amino}-4-methoxy-5-{[4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl]amino ... }phenyl)prop-2-enamide …
Matched Description: … T790M mutation as detected by FDA-approved testing and which has progressed following therapy with a ... Approximately 10% of patients with NSCLC have a rapid and clinically effective response to EGFR-TKIs …
Matched Salts cas: … 1421373-66-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Iupac: … N-(2-{[2-(dimethylamino)ethyl](methyl)amino}-4-methoxy-5-{[4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl]amino ... }phenyl)prop-2-enamide …
Matched Description: … T790M mutation as detected by FDA-approved testing and which has progressed following therapy with a ... Approximately 10% of patients with NSCLC have a rapid and clinically effective response to EGFR-TKIs …
Matched Salts cas: … 1421373-66-1 …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Heterocyclic Compounds, 2-Ring ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Nafcillin
A semi-synthetic antibiotic related to penicillin, Naficillin is a narrow-spectrum beta-lactam antibiotic drug. It is a beta-lactamase-resistant penicillin that is indicated for the treatment of Staphylococcal infections caused by strains that are resistant to other penicillins, except those caused by MRSA. It may be used as a first-line therapy in...
Approved
Investigational
Matched Synonyms: … (2-ethoxy-1-naphthyl)penicillin ... (2-ethoxy-1-naphthalenyl)penicillin ... (2S,5R,6R)-6-[(2-ethoxy-1-naphthoyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic …
Matched Iupac: … (2S,5R,6R)-6-(2-ethoxynaphthalene-1-amido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic …
Matched Description: … A semi-synthetic antibiotic related to penicillin, Naficillin is a narrow-spectrum beta-lactam antibiotic ... It is a beta-lactamase-resistant penicillin that is indicated for the treatment of Staphylococcal infections ... It may be used as a first-line therapy in Methicillin-Sensitive *Staphylococcus aureus* infections [A20360 …
Matched Salts cas: … 985-16-0 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … (2S,5R,6R)-6-(2-ethoxynaphthalene-1-amido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic …
Matched Description: … A semi-synthetic antibiotic related to penicillin, Naficillin is a narrow-spectrum beta-lactam antibiotic ... It is a beta-lactamase-resistant penicillin that is indicated for the treatment of Staphylococcal infections ... It may be used as a first-line therapy in Methicillin-Sensitive *Staphylococcus aureus* infections [A20360 …
Matched Salts cas: … 985-16-0 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Tapentadol
Tapentadol is a centrally-acting synthetic analgesic with a dual mechanism of action. It is a mu-opioid receptor agonist that also inhibits norepinephrine reuptake.[A260721, A36596]
Tapentadol was first approved by the FDA on November 20, 2008. The extended-release formulation of tapentadol was also approved by the FDA on August 26, 2011....
Approved
Matched Synonyms: … 3-[(1R,2R)-3-(Dimethylamino)-1-ethyl-2-methylpropyl]phenol ... PHENOL, 3-((1R,2R)-3-(DIMETHYLAMINO)-1-ETHYL-2-METHYLPROPYL)- …
Matched Iupac: … 3-[(2R,3R)-1-(dimethylamino)-2-methylpentan-3-yl]phenol …
Matched Description: … The extended-release formulation of tapentadol was also approved by the FDA on August 26, 2011. ... Tapentadol is a centrally-acting synthetic analgesic with a dual mechanism of action. ... It is a mu-opioid receptor agonist that also inhibits norepinephrine reuptake. …
Matched Iupac: … 3-[(2R,3R)-1-(dimethylamino)-2-methylpentan-3-yl]phenol …
Matched Description: … The extended-release formulation of tapentadol was also approved by the FDA on August 26, 2011. ... Tapentadol is a centrally-acting synthetic analgesic with a dual mechanism of action. ... It is a mu-opioid receptor agonist that also inhibits norepinephrine reuptake. …
Bisacodyl
Bisacodyl, a diphenylmethane derivative, is a commonly used over the counter stimulant laxative for occasional constipation.[A233300,L13362] Both bisacodyl and picosulfate are metabolized to the same active metabolite bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM).[A233290,A233300,A207700]
Bisacodyl was patented on 25 September 1956 but has been used as a laxative since 1952.
Approved
Matched Synonyms: … Phenol, 4,4'-(2-pyridinylmethylene)bis-, diacetate (ester) …
Matched Iupac: … 4-{[4-(acetyloxy)phenyl](pyridin-2-yl)methyl}phenyl acetate …
Matched Description: … bisacodyl and [picosulfate] are metabolized to the same active metabolite bis-(p-hydroxyphenyl)-pyridyl-2- ... Bisacodyl, a diphenylmethane derivative, is a commonly used over the counter stimulant laxative for occasional ... A233290,A233300,A207700] Bisacodyl was patented on 25 September 1956[L33045] but has been used as a …
Matched Mixtures name: … GaviLyte-H and Bisacodyl ... BEKUNIS 3 MG/5 MG KAPLI TABLET, 30 ADET …
Matched Products: … Lax-A Go ... Feen-A-mint - Ect 5mg …
Matched Iupac: … 4-{[4-(acetyloxy)phenyl](pyridin-2-yl)methyl}phenyl acetate …
Matched Description: … bisacodyl and [picosulfate] are metabolized to the same active metabolite bis-(p-hydroxyphenyl)-pyridyl-2- ... Bisacodyl, a diphenylmethane derivative, is a commonly used over the counter stimulant laxative for occasional ... A233290,A233300,A207700] Bisacodyl was patented on 25 September 1956[L33045] but has been used as a …
Matched Mixtures name: … GaviLyte-H and Bisacodyl ... BEKUNIS 3 MG/5 MG KAPLI TABLET, 30 ADET …
Matched Products: … Lax-A Go ... Feen-A-mint - Ect 5mg …
Interferon alfa-n1
Interferon alfa-n1 consists of purified, natural (n is for natural) alpha interferon subtypes, at least two of which are glycosylated. This differs from recombinant alpha interferons, which are individual non-glycosylated proteins produced from individual alpha interferon genes.
Approved
Investigational
Matched Description: … Interferon alfa-n1 consists of purified, natural (n is for natural) alpha interferon subtypes, at least …
Atomoxetine
Atomoxetine is a selective norepinephrine (NE) reuptake inhibitor used for the treatment of attention deficit hyperactivity disorder (ADHD). Also known as the marketed product Strattera, atomoxetine is used with other treatment modalities (psychological, educational, cognitive behaviour therapy, etc) to improve developmentally inappropriate symptoms associated with ADHD including distractibility, short attention...
Approved
Matched Iupac: … methyl[(3R)-3-(2-methylphenoxy)-3-phenylpropyl]amine …
Matched Description: … have shown that atomoxetine also binds to the serotonin transporter (SERT),[A178111] and blocks the N-methyl-d-aspartate ... and amphetamines, have a high potential for abuse and dependence. ... Atomoxetine is a selective norepinephrine (NE) reuptake inhibitor used for the treatment of attention …
Matched Description: … have shown that atomoxetine also binds to the serotonin transporter (SERT),[A178111] and blocks the N-methyl-d-aspartate ... and amphetamines, have a high potential for abuse and dependence. ... Atomoxetine is a selective norepinephrine (NE) reuptake inhibitor used for the treatment of attention …
Lifitegrast
Lifitegrast is a FDA approved drug for the treatment of keratoconjunctivitis sicca (dry eye syndrome). It is a tetrahydroisoquinoline derivative and lymphocyte function-associated antigen-1 ( LFA-1) antagonist that was discovered through the rational design process. The ophthalmic solution was approved in July, 2016 under the trade name Xiidra. It has...
Approved
Matched Iupac: … (2S)-2-{[2-(1-benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinolin-6-yl]formamido}-3-(3- …
Matched Description: … It is a tetrahydroisoquinoline derivative and lymphocyte function-associated antigen-1 ( LFA-1) antagonist ... Lifitegrast is a FDA approved drug for the treatment of keratoconjunctivitis sicca (dry eye syndrome) …
Matched Categories: … Lymphocyte Function-Associated Antigen-1 ... Lymphocyte Function-Associated Antigen-1 Antagonist ... Lymphocyte Function-Associated Antigen-1 Antagonists ... Compounds used in a research, industrial, or household setting …
Matched Description: … It is a tetrahydroisoquinoline derivative and lymphocyte function-associated antigen-1 ( LFA-1) antagonist ... Lifitegrast is a FDA approved drug for the treatment of keratoconjunctivitis sicca (dry eye syndrome) …
Matched Categories: … Lymphocyte Function-Associated Antigen-1 ... Lymphocyte Function-Associated Antigen-1 Antagonist ... Lymphocyte Function-Associated Antigen-1 Antagonists ... Compounds used in a research, industrial, or household setting …
Nitrofurantoin
Nitrofurantoin is a nitrofuran antibiotic used to treat uncomplicated urinary tract infections.[L6856,L6859,L6862] Nitrofurantoin is converted by bacterial nitroreductases to electrophilic intermediates which inhibit the citric acid cycle as well as synthesis of DNA, RNA, and protein. This drug is more resistant to the development of bacterial resistance because it acts...
Approved
Vet approved
Matched Synonyms: … N-(5-Nitrofurfurylidene)-1-aminohydantoin ... 1-((5-nitro-2-furanyl)methylene)amino-2,4-imidazolidenedione ... 1-((5-nitrofurfurylidene)amino)hydantoin …
Matched Iupac: … 1-[(E)-[(5-nitrofuran-2-yl)methylidene]amino]imidazolidine-2,4-dione …
Matched Description: … Nitrofurantoin is a nitrofuran antibiotic used to treat uncomplicated urinary tract infections. ... [A179824] Nitrofurantoin is a second line treatment to [trimethoprim]/[sulfamethoxazole]. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Iupac: … 1-[(E)-[(5-nitrofuran-2-yl)methylidene]amino]imidazolidine-2,4-dione …
Matched Description: … Nitrofurantoin is a nitrofuran antibiotic used to treat uncomplicated urinary tract infections. ... [A179824] Nitrofurantoin is a second line treatment to [trimethoprim]/[sulfamethoxazole]. …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Zinc gluconate
Zinc gluconate is a zinc salt of gluconic acid comprised of two gluconic acid molecules for each zinc cation (2+). Zinc gluconate is a generally recognized as safe (GRAS) substance by FDA . It is available as a trace mineral supplement and over the counter as a lozenge form for...
Approved
Vet approved
Matched Iupac: … zinc(2+) ion bis((2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate) …
Matched Description: … cation (2+). ... It is available as a trace mineral supplement and over the counter as a lozenge form for a reduced duration ... Zinc gluconate is a generally recognized as safe (GRAS) substance by FDA [L2081]. …
Matched Mixtures name: … Super Daily No 2 ... KORDEL`S EXECUTIVE B TABLET ... A+ Zinc Tab …
Matched Products: … ZINC INJECTABLE A 1mg/ml, solution injectable pour perfusion ... Zink Aguettant 1 mg/ml Konzentrat zur Herstellung einer Infusionslösung …
Matched Description: … cation (2+). ... It is available as a trace mineral supplement and over the counter as a lozenge form for a reduced duration ... Zinc gluconate is a generally recognized as safe (GRAS) substance by FDA [L2081]. …
Matched Mixtures name: … Super Daily No 2 ... KORDEL`S EXECUTIVE B TABLET ... A+ Zinc Tab …
Matched Products: … ZINC INJECTABLE A 1mg/ml, solution injectable pour perfusion ... Zink Aguettant 1 mg/ml Konzentrat zur Herstellung einer Infusionslösung …
Chloroquine
Chloroquine is an aminoquinolone derivative first developed in the 1940s for the treatment of malaria. It was the drug of choice to treat malaria until the development of newer antimalarials such as pyrimethamine, artemisinin, and mefloquine. Chloroquine and its derivative hydroxychloroquine have since been repurposed for the treatment of a...
Approved
Investigational
Vet approved
Matched International brands: … Nivaquine B …
Matched Iupac: … 7-chloro-N-[5-(diethylamino)pentan-2-yl]quinolin-4-amine …
Matched Description: … Chloroquine and its derivative [hydroxychloroquine] have since been repurposed for the treatment of a …
Matched Salts cas: … 3545-67-3 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Iupac: … 7-chloro-N-[5-(diethylamino)pentan-2-yl]quinolin-4-amine …
Matched Description: … Chloroquine and its derivative [hydroxychloroquine] have since been repurposed for the treatment of a …
Matched Salts cas: … 3545-67-3 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Interferon alfa-n3
Purified, natural (n is for natural) human interferon alpha proteins (consists of 3 forms or polymorphisms including 2a, 2b and 2c). 166 residues, some are glycosylated (MW range from 16 kD to 27 kD).
Approved
Investigational
Matched International brands: … Alferon N …
Matched Description: … Purified, natural (n is for natural) human interferon alpha proteins (consists of 3 forms or polymorphisms ... including 2a, 2b and 2c). 166 residues, some are glycosylated (MW range from 16 kD to 27 kD). …
Matched Description: … Purified, natural (n is for natural) human interferon alpha proteins (consists of 3 forms or polymorphisms ... including 2a, 2b and 2c). 166 residues, some are glycosylated (MW range from 16 kD to 27 kD). …
Almotriptan
Almotriptan is a triptan drug for the treatment of migraine headaches. Almotriptan is in a class of medications called selective serotonin receptor agonists. It works by narrowing blood vessels in the brain, stopping pain signals from being sent to the brain, and stopping the release of certain natural substances that...
Approved
Investigational
Matched Synonyms: … 1-(((3-(2-(Dimethylamino)ethyl)indol-5-yl)methyl)sulfonyl)pyrrolidine …
Matched Iupac: … dimethyl(2-{5-[(pyrrolidine-1-sulfonyl)methyl]-1H-indol-3-yl}ethyl)amine …
Matched Description: … Almotriptan is a triptan drug for the treatment of migraine headaches. ... Almotriptan is in a class of medications called selective serotonin receptor agonists. …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Monoamine Oxidase A Substrates …
Matched Iupac: … dimethyl(2-{5-[(pyrrolidine-1-sulfonyl)methyl]-1H-indol-3-yl}ethyl)amine …
Matched Description: … Almotriptan is a triptan drug for the treatment of migraine headaches. ... Almotriptan is in a class of medications called selective serotonin receptor agonists. …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Monoamine Oxidase A Substrates …
Sofosbuvir
Sofosbuvir (tradename Sovaldi) is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the...
Approved
Matched Synonyms: … S)-Isopropyl 2-((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4- dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4 ... -methyltetrahydrofuran-2-yl)methoxy)- (phenoxy)phosphorylamino)propanoate …
Matched Iupac: … propan-2-yl (2S)-2-{[(S)-{[(2R,3R,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-4-fluoro-3-hydroxy ... -4-methyloxolan-2-yl]methoxy}(phenoxy)phosphoryl]amino}propanoate …
Matched Description: … HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 ... 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-triphosphate (also known as GS-461203), which acts as a defective ... Treatment options for chronic Hepatitis C have advanced significantly since 2011, with the development …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Hepatitis C Virus Nucleotide Analog NS5B Polymerase Inhibitor …
Matched Iupac: … propan-2-yl (2S)-2-{[(S)-{[(2R,3R,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-4-fluoro-3-hydroxy ... -4-methyloxolan-2-yl]methoxy}(phenoxy)phosphoryl]amino}propanoate …
Matched Description: … HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 ... 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-triphosphate (also known as GS-461203), which acts as a defective ... Treatment options for chronic Hepatitis C have advanced significantly since 2011, with the development …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Hepatitis C Virus Nucleotide Analog NS5B Polymerase Inhibitor …
Hydroxyprogesterone caproate
Hydroxyprogesterone caproate is a synthetic steroid hormone that is similar to medroxyprogesterone acetate and megestrol acetate. It is an ester derivative of 17α-hydroxyprogesterone formed from caproic acid (hexanoic acid). Hydroxyprogesterone caproate was previously marketed under the trade name Delalutin by Squibb, which was approved by the U.S. Food and Drug...
Approved
Investigational
Matched Iupac: … 11H,11aH-cyclopenta[a]phenanthren-1-yl hexanoate ... (1R,3aS,3bR,9aR,9bS,11aS)-1-acetyl-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H, …
Matched Description: … FDA approved Makena from KV Pharmaceutical (previously named as Gestiva) on February 4, 2011 for prevention ... of preterm delivery in women with a history of preterm delivery, sparking a pricing controversy. ... Hydroxyprogesterone caproate is a synthetic steroid hormone that is similar to medroxyprogesterone acetate …
Matched Mixtures name: … GRAVIDINONA 2 ML …
Matched Products: … LUGESRO 500 MG/2 ML ENJEKSİYONLUK ÇÖZELTİ, 1 ADET ... PROLUTON DEPOT 500 MG/2ML IM ENJEKSIYONLUK COZELTI ICEREN AMPUL, 1 ADET …
Matched Description: … FDA approved Makena from KV Pharmaceutical (previously named as Gestiva) on February 4, 2011 for prevention ... of preterm delivery in women with a history of preterm delivery, sparking a pricing controversy. ... Hydroxyprogesterone caproate is a synthetic steroid hormone that is similar to medroxyprogesterone acetate …
Matched Mixtures name: … GRAVIDINONA 2 ML …
Matched Products: … LUGESRO 500 MG/2 ML ENJEKSİYONLUK ÇÖZELTİ, 1 ADET ... PROLUTON DEPOT 500 MG/2ML IM ENJEKSIYONLUK COZELTI ICEREN AMPUL, 1 ADET …
Nebivolol
Nebivolol is a racemic mixture of 2 enantiomers where one is a beta adrenergic antagonist and the other acts as a cardiac stimulant without beta adrenergic activity. Treatment with nebivolol leads to a greater decrease in systolic and diastolic blood pressure than atenolol, propranolol, or pindolol. Nebivolol and other beta...
Approved
Investigational
Matched Iupac: … 1-(6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl)-2-{[2-(6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl)-2-hydroxyethyl ... ]amino}ethan-1-ol …
Matched Description: … Nebivolol is a racemic mixture of 2 enantiomers where one is a beta adrenergic antagonist and the other ... acts as a cardiac stimulant without beta adrenergic activity. ... [A182579] Treatment with nebivolol leads to a greater decrease in systolic and diastolic blood pressure …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Adrenergic beta-1 Receptor Agonists ... Heterocyclic Compounds, 1-Ring …
Matched Products: … CORETEL-N …
Matched Description: … Nebivolol is a racemic mixture of 2 enantiomers where one is a beta adrenergic antagonist and the other ... acts as a cardiac stimulant without beta adrenergic activity. ... [A182579] Treatment with nebivolol leads to a greater decrease in systolic and diastolic blood pressure …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Adrenergic beta-1 Receptor Agonists ... Heterocyclic Compounds, 1-Ring …
Matched Products: … CORETEL-N …
Edetic acid
A chelating agent (chelating agents) that sequesters a variety of polyvalent cations. It is used in pharmaceutical manufacturing and as a food additive.
Approved
Vet approved
Matched Synonyms: … 2,2',2'',2'''-(ethane-1,2-diyldinitrilo)tetraacetate ... N,N'-1,2-Ethane diylbis-(N-(carboxymethyl)glycine) …
Matched Iupac: … 2-({2-[bis(carboxymethyl)amino]ethyl}(carboxymethyl)amino)acetic acid …
Matched Description: … A chelating agent (chelating agents) that sequesters a variety of polyvalent cations. ... It is used in pharmaceutical manufacturing and as a food additive. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Iupac: … 2-({2-[bis(carboxymethyl)amino]ethyl}(carboxymethyl)amino)acetic acid …
Matched Description: … A chelating agent (chelating agents) that sequesters a variety of polyvalent cations. ... It is used in pharmaceutical manufacturing and as a food additive. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Displaying drugs 276 - 300 of 13578 in total