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Displaying drugs 276 - 300 of 811 in total

PEP0101

PEP0101 is a nanocomplex consisting of elastin-like polypeptides and a small interfering RNA (siRNA) designed to down-regulate the expression of EVI1 oncogene in cancer cells.
Investigational
Matched Synonyms: … Nanocomplex consisting of a small interfering RNA that targets the human EV11 oncogenic transcription factor and …
Matched Description: … PEP0101 is a nanocomplex consisting of elastin-like polypeptides and a small interfering RNA (siRNA) …

Cefotaxime

Cefotaxime is a third-generation cephalosporin antibiotic. Like other third-generation cephalosporins, it has broad spectrum activity against Gram positive and Gram negative bacteria. In most cases, it is considered to be equivalent to ceftriaxone in terms of safety and efficacy. Cefotaxime sodium is marketed under various trade names including Claforan (Sanofi-Aventis).
Approved
Matched Description: … Cefotaxime sodium is marketed under various trade names including Claforan (Sanofi-Aventis). ... Like other third-generation cephalosporins, it has broad spectrum activity against Gram positive and ... In most cases, it is considered to be equivalent to ceftriaxone in terms of safety and efficacy. …
Matched Salts name: … Cefotaxime sodium …
Matched Products: … Cefotaxime and Dextrose ... Cefotaxime Sodium Sterile ... CEFOTAXIME SODIUM …

Hiltonol

Investigational
Matched Synonyms: … homopolymer, complex with 5'-inosinic acid homopolymer (1:1), compd. with cellulose carboxymethyl ether and ... homopolymer, complex with 5'-cytidylic acid homopolymer (1:1), compd. with cellulose carboxymethyl ether and ... L-lysine, homopolymer, compd. with cellulose carboxymethyl ether and 5'-inosinic acid homopolymer complex …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... Nucleic Acids, Nucleotides, and Nucleosides …

Thimerosal

Thiomersal (INN), commonly known in the U.S. as thimerosal, is an organomercury compound. This compound is a well-established and widely used antiseptic and antifungal agent. Developed in 1927, thimerosal has been and is still being used as a preservative in some cosmetics, topical pharmaceuticals, and biological drug products, which includes...
Approved
Matched Synonyms: … sodium merthiolate ... ethylmercurithiosalicylate sodium ... sodium ethylmercurithiosalicylate …
Matched Iupac: … sodium [(2-carboxylatophenyl)sulfanyl](ethyl)mercury …
Matched Description: … This compound is a well-established and widely used antiseptic and antifungal agent. ... pharmaceuticals, and biological drug products, which includes vaccines. ... There has been significant concern regarding its safety and toxicity in the last several decades. …
Matched Categories: … Antiseptics and Disinfectants …

Vasopressin

Vasopressin (arginine-vasopressin or antidiuretic hormone) is a nonapeptide primarily produced in the hypothalamus that exhibits diverse physiological functions related to diuresis, hemodynamic modulation, and behaviour.[A110, A111, A112, A113, A228008] Vasopressin is very similar to oxytocin, differing in the third and eighth amino acids. Despite a wide variety of functions, exogenous...
Approved
Matched Description: … renal fluid reuptake by acting through V1 and V2 cellular receptors. ... hypothalamus that exhibits diverse physiological functions related to diuresis, hemodynamic modulation, and ... [A110, A111, A112, A113, A228008] Vasopressin is very similar to oxytocin, differing in the third and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Vasopressin and Analogues ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Vasopressin in 0.9% Sodium Chloride …

Parnaparin

Parnaparin is an heparin of low molecular weight with antithrombotic effects.
Approved
Investigational
Matched Synonyms: … Parnaparin sodium …
Matched Categories: … Blood and Blood Forming Organs ... Heparin and similars …

Zenocutuzumab

Zenocutuzumab is under investigation in clinical trial NCT03321981 (MCLA-128 With Trastuzumab/chemotherapy in HER2+ and With Endocrine Therapy in ER+ and Low HER2 Breast Cancer).
Investigational
Matched Synonyms: … Immunoglobulin g1, bispecific, anti-(human epidermal growth factor receptors, her2 and her3) (humanized ... antibody with enhanced antibody-dependent cell-mediated cytotoxicity (adcc) activity targeting her2 and …
Matched Description: … With Endocrine Therapy in ER+ and Low HER2 Breast Cancer). ... under investigation in clinical trial NCT03321981 (MCLA-128 With Trastuzumab/chemotherapy in HER2+ and …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Sodium phosphate, dibasic

Approved
Matched Synonyms: … Dibasic sodium phosphate anhydrous ... Sodium phosphate dibasic ... Sodium phosphate, dibasic …
Matched Name: … Sodium phosphate, dibasic …
Matched Mixtures name: … Heparin Sodium In 0.9% Sodium Chloride Injection ... Monobasic Sodium Phosphate and Dibasic Sodium Phosphate ... Monobasic Sodium Phosphate and Dibasic Sodium Phosphate …
Matched Salts name: … Sodium phosphate, dibasic dihydrate ... Sodium phosphate, dibasic dodecahydrate ... Sodium phosphate, dibasic, heptahydrate ... Sodium phosphate, dibasic, monohydrate …

Bisacodyl

Bisacodyl, a diphenylmethane derivative, is a commonly used over the counter stimulant laxative for occasional constipation.[A233300,L13362] Both bisacodyl and picosulfate are metabolized to the same active metabolite bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM).[A233290,A233300,A207700] Bisacodyl was patented on 25 September 1956 but has been used as a laxative since 1952.
Approved
Matched Description: … [A233300,L13362] Both bisacodyl and [picosulfate] are metabolized to the same active metabolite bis-( …
Matched Mixtures name: … HalfLytely and Bisacodyl ... HalfLytely and Bisacodyl ... GaviLyte-H and Bisacodyl …
Matched Categories: … Alimentary Tract and Metabolism …
Matched Products: … Carters Little Pills Sodium-Free ... Up and Up womens laxative ... Up and Up Gentle Laxative …

Triptorelin

Triptorelin is a synthetic decapeptide agonist analog of luteinizing hormone releasing hormone (LHRH). Possessing greater potency than endogenous LHRH, triptorelin reversibly represses gonadotropin secretion. After chronic, continuous administration, this agent effects sustained decreases in LH and FSH production and testicular and ovarian steroidogenesis. Serum testosterone concentrations may fall to levels...
Approved
Vet approved
Matched Description: … and testicular and ovarian steroidogenesis. ... After chronic, continuous administration, this agent effects sustained decreases in LH and FSH production …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Hormones and Related Agents ... Antineoplastic and Immunomodulating Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION 11.25 mg/vial ... POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION 3.75 mg/vial …

Witch hazel

Nutraceutical
Matched Mixtures name: … frida mom Labor and Delivery Plus Postpartum Recovery ... frida mom Labor and Delivery Plus Postpartum Recovery ... Tucks Multi-Care Relief Kit (Tucks Hemorrhoidal and Tucks Medicated Cooling 40 Count) …
Matched Categories: … Astringents and Deodorants ... Herbs and Natural Products ... Skin and Mucous Membrane Agents …
Matched Products: … Up and Up Medicated Hemorrhoidal Pads ... Tone and Line Change Pack ... Hamsoa Atoby Medi Bath And …

Taniraleucel

Investigational
Matched Synonyms: … Flt3 ligand, IL-7, IL-15 and IL-2 to generate the NK cell ... The cells are expanded and differentiated in the presence of cytokines including thrombopoietin, SCF, …

Pacanalotamab

Investigational
Matched Synonyms: … engager antibody with a single chain fc moiety that binds to b cell maturation antigen surface receptor and …

Reviparin

Reviparin is a low molecular weight heparin which seems to have a better safety profile than unfractionated heparin. It is prepared from porcine intestinal mucosa by nitrous acid depolymerization. Reviparin has a molecular weight of 3.9 kDa. It was developed by Abbott laboratories and in 2009, reviparin presented an orphan...
Approved
Investigational
Matched Synonyms: … Reviparin sodium …
Matched Description: … [A32021] It was developed by Abbott laboratories and in 2009, reviparin presented an orphan drug designation …
Matched Categories: … Blood and Blood Forming Organs ... Heparin and similars …

Esomeprazole

Esomeprazole, sold under the brand name Nexium, is a proton pump inhibitor (PPI) medication used for the management of gastroesophageal reflux disease (GERD), for gastric protection to prevent recurrence of stomach ulcers or gastric damage from chronic use of NSAIDs, and for the treatment of pathological hypersecretory conditions including Zollinger-Ellison...
Approved
Investigational
Matched Description: … and bone fractures later in life. ... B12, and an increased risk of developing hypomagnesemia and hypocalcemia which may contribute to osteoporosis ... Esomeprazole is the s-isomer of [DB00338], which is a racemate of the S- and R-enantiomer. …
Matched Mixtures name: … Naproxen and esomeprazole magnesium ... Naproxen and esomeprazole magnesium ... Naproxen and Esomeprazole Magnesium …
Matched Salts name: … Esomeprazole sodium …
Matched Categories: … Alimentary Tract and Metabolism ... Omeprazole and enantiomer ... Antiinflammatory and Antirheumatic Products ... naproxen and esomeprazole ... Antiinflammatory and Antirheumatic Products, Non-Steroids …
Matched Products: … Esomeprazole Sodium ... Esomeprazole sodium ... ESOMEPRAZOLE SODIUM …

Sodium carbonate

Sodium Carbonate is the disodium salt of carbonic acid with alkalinizing property. When dissolved in water, sodium carbonate forms carbonic acid and sodium hydroxide. As a strong base, sodium hydroxide neutralizes gastric acid thereby acting as an antacid.
Approved
Matched Synonyms: … Anhydrous sodium carbonate ... Carbonic acid sodium salt (1:2) ... Sodium carbonate anhydrous …
Matched Name: … Sodium carbonate …
Matched Description: … When dissolved in water, sodium carbonate forms carbonic acid and sodium hydroxide. ... Sodium Carbonate is the disodium salt of carbonic acid with alkalinizing property. ... As a strong base, sodium hydroxide neutralizes gastric acid thereby acting as an antacid. …

Iodide I-131

Iodide I-131 (as Sodium iodide I-131) is a radioisotopic drug used for the treatment and palliation of thyroid malignancy. Iodine-131 is notable for causing mutation and death in cells that it penetrates, which is due to its mode of beta decay. As a result of beta decay, approximately 10% of...
Approved
Investigational
Matched Description: … Iodide I-131 (as Sodium iodide I-131) is a radioisotopic drug used for the treatment and palliation of ... Therapeutic solutions of Sodium Iodide-131 are indicated for the treatment of hyperthyroidism and thyroid ... Iodine-131 is notable for causing mutation and death in cells that it penetrates, which is due to its …
Matched Salts name: … Sodium iodide I-131 …
Matched Categories: … sodium iodide (131I) ... sodium iodide (131I) …
Matched Products: … Sodium Iodide I 131 ... Sodium Iodide I-131 ... Sodium Iodide I 131 Therapeutic …

Zinc chloride

Zinc chloride is a solution of ions indicated for use in total parenteral nutrition to maintain zinc levels and prevent deficiency syndromes. Zinc chloride was granted FDA approval before 26 June 1986.
Approved
Investigational
Matched Synonyms: … Zinc chloride …
Matched Name: … Zinc chloride …
Matched Description: … levels and prevent deficiency syndromes. ... [L14189] Zinc chloride was granted FDA approval before 26 June 1986.[L14189] ... Zinc chloride is a solution of ions indicated for use in total parenteral nutrition to maintain zinc …
Matched Mixtures name: … Topco 4x Medicated Toothache and Gum Gel ... Benzocaine, Menthol, Zinc Chloride ... Benzocaine, Menthol, Zinc Chloride …
Matched Categories: … zinc chloride ... Chlorine Compounds ... Basic Ointments and Protectants ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions …
Matched Products: … Dermagran II Moisturiz.spray-liq Top 1mg/ml ... Zinc Chloride ... Perioselect Zinc Chloride Solution 1% …

Talquetamab

Talquetamab is a IgG4-PAA bispecific G protein-coupled receptor class C group 5 member D (GPRC5D)-directed CD3 T-cell engager. It consists of two arms - anti-GPRC5D and anti-CD3 arms - linked by two interchain disulfide bonds, each arm comprising a heavy and light chain. Talquetamab binds to GPRC5D, a cell surface...
Approved
Investigational
Matched Synonyms: … -KAPPA/G4-LAMBDA, ANTI-(HOMO SAPIENS GPRC5D (G PROTEIN-COUPLED RECEPTOR CLASS C GROUP 5 MEMBER D)), AND ... ANTI-(HOMO SAPIENS CD3E (CD3 EPSILON, LEU-4)), HUMANIZED AND CHIMERIC MONOCLONAL ANTIBODY, BISPECIFIC ... -KAPPA/G4-LAMBDA, ANTI-(HOMO SAPIENS GPRC5D (G PROTEIN-COUPLED RECEPTOR CLASS C GROUP 5 MEMBER D)), AND …
Matched Description: … arm comprising a heavy and light chain. ... It consists of two arms - anti-GPRC5D and anti-CD3 arms - linked by two interchain disulfide bonds, each ... Talquetamab binds to GPRC5D, a cell surface receptor expressed predominantly on multiple myeloma cells, and …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …

Suratadenoturev

Suratadenoturev is a gene-modified oncolytic adenovirus expressing the telomerase reverse transcriptase gene.
Investigational
Matched Synonyms: … telomerase reverse transcriptase (hTERT) and IRES, respectively. ... -5) in which the E1 gene, including its normal transcriptional regulatory element, has been deleted and ... A replication-competent adenovirus type 5 in which the E1A and E1B genes are under the control of a human …

Meropenem

Meropenem is a broad-spectrum carbapenem antibiotic. It is active against Gram-positive and Gram-negative bacteria. Meropenem exerts its action by penetrating bacterial cells readily and interfering with the synthesis of vital cell wall components, which leads to cell death. In August 2017, a combination antibacterial therapy under the market name vabomere...
Approved
Investigational
Matched Description: … Vabomere consists of meropenem and [DB12107] and is intravenously admininstered. ... It is active against Gram-positive and Gram-negative bacteria. ... Meropenem exerts its action by penetrating bacterial cells readily and interfering with the synthesis …
Matched Salts name: … Meropenem sodium …
Matched Categories: … meropenem and vaborbactam …
Matched Products: … Meropenem and Sodium Chloride ... Meropenem for Injection USP and Sodium Chloride Injection USP …

Dociparstat sodium

Investigational
Matched Synonyms: … Dociparstat sodium …
Matched Name: … Dociparstat sodium …
Matched Categories: … Heparin and similars …

Lanolin

Lanolin is a yellow fat obtained from sheep's wool. It is used as an emollient, cosmetic, and pharmaceutic aid . The US federal code of regulations states that lanolin in the concentration range of 12-50% may be included in over the counter skin ointments . Lanolin is the purified, secreted...
Approved
Matched Description: … It is used as an emollient, cosmetic, and pharmaceutic aid [L2580]. ... Lanolin is used in the protection, treatment, and cosmetic enhancement of human skin. ... as an active ingredient in over the counter topical products such as ointments, lubricants, lotions and …
Matched Mixtures name: … PETROLATUM and LANOLIN ... A and D Diaper Rash and Skin Protectant ... Vitamins A and D Diaper Rash …
Matched Categories: … Basic Ointments and Protectants …
Matched Products: … Soothe and Cool Free Medseptic Skin Protectant …

Glycerin

A trihydroxy sugar alcohol that is an intermediate in carbohydrate and lipid metabolism.
Approved
Investigational
Matched Description: … A trihydroxy sugar alcohol that is an intermediate in carbohydrate and lipid metabolism. …
Matched Mixtures name: … Nature and Health Beauty (Moisturizing Cream, Whitening Cream) (Mineral Oil and Glycerin) ... Up and Up Hemorrhoidal ... Nature and Health Beauty (Moisturizing Cream, Whitening Cream) (Mineral Oil and Glycerin) …
Matched Categories: … Alimentary Tract and Metabolism ... Basic Ointments and Protectants ... Other Cold and Cough Preparations …
Matched Products: … Eros Extended Love 2 Top Level ... Eros Extended Love 3 Top Level ... Eros Extended Love 1 Top Level …

AB-201

AB-201 is a CAR-NK cell therapy targeted against HER2. It is under investigation for the treatment of HER2-positive cancers, including breast and gastric carcinomas.
Investigational
Matched Synonyms: … allogeneic cord blood-derived NK cells that have been genetically modified to express a HER2-directed CAR and …
Matched Description: … [L48340] It is under investigation for the treatment of HER2-positive cancers, including breast and gastric …
Displaying drugs 276 - 300 of 811 in total