Advanced Filter

Filter by Group

Filter by Market Availability

Clear
Did you mean international_brands 3aacet 20 and approved 3atrue?
Displaying drugs 276 - 300 of 5024 in total

Gallium nitrate

Gallium nitrate is a nitrate salt of DB14524, a heavy metal that has been used as a diagnostic agent. Gallium nitrate is reported to possess antiresorptive and hypocalcemic effects on bone. GANITE, a product of gallium nitrate previously used to treat cancer-related hypercalcemia, was discontinued from marketing in the US...
Approved
Investigational
Matched Iupac: … gallium(3+) trinitrate …
Matched Description: … Gallium nitrate is a nitrate salt of [DB14524], a heavy metal that has been used as a diagnostic agent ... [A260816] Gallium nitrate is reported to possess antiresorptive and hypocalcemic effects on bone. ... cancer-related hypercalcemia, gallium nitrate has been studied in arthritis, autoimmune disorders, and …
Matched Salts cas: … 135886-70-3 …
Matched Categories: … Calcium-Regulating Hormones and Agents …

Foscarnet

An antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpes viruses and HIV.
Approved
Matched Description: … Foscarnet also shows activity against human herpes viruses and HIV. …

Cycloserine

Antibiotic substance produced by Streptomyces garyphalus.
Approved
Matched Synonyms: … (+)-4-amino-3-isoxazolidinone ... D-4-amino-3-isoxazolidone ... D-4-amino-3-isoxazolidinone …
Matched Iupac: … (4R)-4-amino-1,2-oxazolidin-3-one …
Matched Categories: … Amino Acids, Peptides, and Proteins …

Metoprolol

Metoprolol is a selective beta-1 blocker commonly employed as the succinate and tartrate derivatives depending if the formulation is designed to be of immediate release or extended release.[A175159, L5530] The possibility of the generation of these formulations comes from the lower systemic bioavailability of the succinate derivative. To this date,...
Approved
Investigational
Matched Synonyms: … 1-(isopropylamino)-3-[4-(2-methoxyethyl)phenoxy]propan-2-ol …
Matched Iupac: … 1-[4-(2-methoxyethyl)phenoxy]-3-[(propan-2-yl)amino]propan-2-ol …
Matched Description: … Metoprolol is a selective beta-1 blocker commonly employed as the succinate and tartrate derivatives ... [A175162] Metoprolol was developed since 1969 by US Pharmaceutical Holdings I and FDA approved in 1978 ... widely prescribed in the Netherlands, New Zealand, and the US. …
Matched Mixtures name: … Metoprolol Tartrate and Hydrochlorothiazide ... Metoprolol Tartrate and Hydrochlorothiazide ... Metoprolol Tartrate and Hydrochlorothiazide …
Matched Categories: … metoprolol and thiazides ... metoprolol and felodipine ... metoprolol and ivabradine ... metoprolol and amlodipine ... metoprolol and other diuretics …

Olaparib

Olaparib is a selective and potent inhibitor of poly (ADP-ribose) polymerase (PARP) enzymes, PARP1 and PARP2.[L41100, L40908, L43792] PARP inhibitors represent a novel class of anti-cancer therapy and they work by taking advantage of a defect in DNA repair in cancer cells with BRCA mutations and inducing cell death. Olaparib...
Approved
Matched Synonyms: … 4-(3-{[4-(cyclopropylcarbonyl)piperazin-1-yl]carbonyl}-4-fluorobenzyl)phthalazin-1(2H)-one …
Matched Iupac: … 4-{[3-(4-cyclopropanecarbonylpiperazine-1-carbonyl)-4-fluorophenyl]methyl}-1,2-dihydrophthalazin-1-one …
Matched Description: … [L41100, L40908, L43792] It was first approved by the FDA and EU in December 2014,[A246020] and by Health ... Olaparib is a selective and potent inhibitor of poly (ADP-ribose) polymerase (PARP) enzymes, PARP1 and ... [L41100, L40908, L43792] PARP inhibitors represent a novel class of anti-cancer therapy and they work …
Matched Categories: … MATE 2-K Inhibitors ... Antineoplastic and Immunomodulating Agents ... P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A5 Substrates with a Narrow Therapeutic Index …

Loncastuximab tesirine

Relapsed and refractory B-cell acute lymphoblastic leukemia (B-ALL) are a therapeutic challenge for patients who have undergone prior systemic therapies with limited success. Prognosis is poor and more effective therapies are needed to treat relapsed/refractory cases and improve survival. On April 23 2021, the Food and Drug Administration granted accelerated...
Approved
Investigational
Matched Synonyms: … Humanized monoclonal immunoglobulin G1 antibody directed against human CD19 conjugated to SG3199 through A …
Matched Description: … Relapsed and refractory B-cell acute lymphoblastic leukemia (B-ALL) are a therapeutic challenge for patients ... refractory B-cell lymphoma is based on promising results from the LOTIS-2 clinical trial. ... and improve survival. …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents ... MONOCLONAL ANTIBODIES AND ANTIBODY DRUG CONJUGATES …

Chlorpheniramine

A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications. One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than promethazine.
Approved
Matched Synonyms: … 3-(p-chlorophenyl)-3-(2-pyridyl)-N,N-dimethylpropylamine ... 1-(p-chlorophenyl)-1-(2-pyridyl)-3-dimethylaminopropane ... 1-(p-chlorophenyl)-1-(2-pyridyl)-3-N,N-dimethylpropylamine …
Matched Iupac: … [3-(4-chlorophenyl)-3-(pyridin-2-yl)propyl]dimethylamine …
Matched Description: … A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. ... One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and …
Matched Salts cas: … 25387-68-2 …
Matched Mixtures name: … A-FERİN 300 MG/2 MG/10 MG KAPSÜL, 20 ADET ... A-FERİN 300 MG/2 MG/10 MG KAPSÜL, 30 ADET ... A-FERİN 300 MG/2 MG/10 MG KAPSÜL, 500 ADET …
Matched Products: … คลอเฟน 2 ... AXCEL CHLORPHENIRAMINE-2 SYRUP ... CHLORPHENIRAMINE TABLETS (2 MG.) …

Procaine

A local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1016). Procaine has also been investigated as an oral entry inhibitor in...
Approved
Investigational
Vet approved
Matched Synonyms: … 2-Diethylaminoethyl p-aminobenzoate ... 4-aminobenzoic acid 2-diethylaminoethyl ester ... p-Aminobenzoic acid 2-diethylaminoethyl ester …
Matched Iupac: … 2-(diethylamino)ethyl 4-aminobenzoate …
Matched Description: … A local anesthetic of the ester type that has a slow onset and a short duration of action. ... It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. …
Matched Salts cas: … 6192-92-3 …
Matched Categories: … Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use …
Matched Products: … Novocain Liq 2% ... PROCANOL LOTION 2% ... VERSENIKCAINA® 2% …

Fenbufen

Fenbufen is a non-steroidal anti-inflammatory drug used primarily to treat inflammation in osteoarthritis, ankylosing spondylitis, and tendinitis. It can also be used to relieve backaches, sprains, and fractures. Fenbufen is available as a capsule or tablet sold with the brand names Cepal, Cinopal, Cybufen, Lederfen, and Reugast. Fenbufen acts by...
Approved
Matched Synonyms: … 3-(4-Phenylbenzoyl)propionic acid ... 3-(4-Biphenylylcarbonyl)propionic acid …
Matched Description: … , and Reugast. ... , ankylosing spondylitis, and tendinitis. ... Fenbufen is a non-steroidal anti-inflammatory drug used primarily to treat inflammation in osteoarthritis …
Matched Categories: … Non COX-2 selective NSAIDS ... Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids …

Sodium bicarbonate

Sodium bicarbonate is a white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.
Approved
Matched Description: … replenisher, systemic alkalizer and in topical cleansing solutions. ... Sodium bicarbonate is a white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte …
Matched Mixtures name: … SUSPENSION ORAL CON SABOR A MENTA ... SUSPENSION ORAL CON SABOR A MENTA ... GAVISCON® TABLETAS MASTICABLES SABOR A MENTA …
Matched Categories: … Antacids and Adsorbents ... Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions …
Matched Products: … Arm and Hammer Baking Soda …

Pheneticillin

Pheneticillin (or phenethicillin) is a penicillin antibiotic which is approved for use internationally.
Approved
Matched Iupac: … (2S,5R,6R)-3,3-dimethyl-7-oxo-6-(2-phenoxypropanamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic …
Matched Description: … Pheneticillin (or phenethicillin) is a penicillin antibiotic which is approved for use internationally …

Lymecycline

Lymecycline is a broad-spectrum second-generation tetracycline antibiotic used for the treatment of acne and other susceptible bacterial infections.[L13880,L13883] It has been proven a cost-effective alternative to treatment with minocycline with comparable safety and efficacy. Lymecycline was initially discovered in 1961. It is marketed by Galderma and used in the UK...
Approved
Investigational
Matched Synonyms: … dimethylamino-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxonaphthacene-2- ... N6-((4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2- …
Matched Iupac: … yl]formamido}methyl)amino]-2-aminohexanoic acid ... dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracen-2- …
Matched Description: … comparable safety and efficacy. ... Lymecycline is a broad-spectrum second-generation tetracycline antibiotic used for the treatment of acne ... [L13880,L13883] It has been proven a cost-effective alternative to treatment with [minocycline] with …

Gefitinib

Gefitinib (originally coded ZD1839) is a drug used in the treatment of certain types of cancer. Acting in a similar manner to erlotinib (marketed as Tarceva), gefitinib selectively targets the mutant proteins in malignant cells. It is marketed by AstraZeneca under the trade name Iressa.
Approved
Investigational
Matched Synonyms: … 4-(3'-chloro-4'-fluoroanilino)-7-methoxy-6-(3-morpholinopropoxy)quinazoline ... N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-(4-morpholinyl)propoxy)-4-quinazolinamine …
Matched Iupac: … N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(morpholin-4-yl)propoxy]quinazolin-4-amine …
Matched Description: … Gefitinib (originally coded ZD1839) is a drug used in the treatment of certain types of cancer. ... Acting in a similar manner to erlotinib (marketed as Tarceva), gefitinib selectively targets the mutant …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Antineoplastic and Immunomodulating Agents …

Hydrocortisone butyrate

Approved
Vet approved
Matched Iupac: … ,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl butanoate ... (1R,3aS,3bS,9aR,9bS,10S,11aS)-10-hydroxy-1-(2-hydroxyacetyl)-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H …
Matched Categories: … Hydrocortisone and derivatives ... hydrocortisone butyrate and antiseptics ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Dexfenfluramine

Dexfenfluramine, also marketed under the name Redux, is a serotoninergic anorectic drug. For a fairly limited time during the middle of the nineties, the US FDA had approved it for use in managing weight loss. However, following multiple concerns about the cardiovascular side-effects of the drug, such approval was withdrawn.
Approved
Illicit
Investigational
Withdrawn
Matched Synonyms: … (S)-N-ethyl-1-[3-(trifluoromethyl)phenyl]propan-2-amine …
Matched Iupac: … ethyl[(2S)-1-[3-(trifluoromethyl)phenyl]propan-2-yl]amine …
Matched Description: … For a fairly limited time during the middle of the nineties, the US FDA had approved it for use in managing ... Dexfenfluramine, also marketed under the name Redux, is a serotoninergic anorectic drug. …
Matched Categories: … Alimentary Tract and Metabolism …

Diclofenamide

A carbonic anhydrase inhibitor that is used in the treatment of glaucoma.
Approved
Investigational
Matched Description: … A carbonic anhydrase inhibitor that is used in the treatment of glaucoma. …
Matched Categories: … Antiglaucoma Preparations and Miotics ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics …

Inosine pranobex

Inosine pranobex (Isoprinosine or Methisoprinol) is a combination of inosine, acetamidobenzoic acid, and dimethylaminoisopropanol used as an antiviral drug.
Approved
Matched Synonyms: … Inosine-2-hydroxypropyldimethylammonium 4-acetamidobenzoate (1:3) …
Matched Iupac: … -5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-1H-purin-6-one ... tris((2R)-1-(dimethylamino)propan-2-ol); tris(4-acetamidobenzoic acid); 9-[(2R,3R,4S,5R)-3,4-dihydroxy …
Matched Description: … and dimethylaminoisopropanol used as an antiviral drug. ... Inosine pranobex (Isoprinosine or Methisoprinol) is a combination of inosine, acetamidobenzoic acid, …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Nucleic Acids, Nucleotides, and Nucleosides …

Retapamulin

Retapamulin, marketed by GlaxoSmithKline as the ointment Altabax, is an antibiotic for skin infections like impetigo. It was approved by the FDA in April 2007.
Approved
Matched Iupac: … -6-yl 2-{[(1R,3S,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl]sulfanyl}acetate ... (1S,2R,3S,4S,6R,7R,8R,14R)-4-ethenyl-3-hydroxy-2,4,7,14-tetramethyl-9-oxotricyclo[5.4.3.0^{1,8}]tetradecan …
Matched Description: … It was approved by the FDA in April 2007. …

Nadofaragene firadenovec

Nadofaragene firadenovec (nadofaragene firadenovec-vncg) is a recombinant non-replicating adenovirus serotype 5 vector containing a transgene encoding human interferon alfa-2b (IFNα2b). It was approved by the FDA on December 2022 for the treatment of high-risk Bacillus Calmette-Guérin (BCG)-unresponsive non-muscle invasive bladder cancer (NMIBC) with carcinoma in situ (CIS) with or without...
Approved
Investigational
Matched Synonyms: … Replication-deficient adenovirus type 5 (ad5) vector encoding the human interferon alpha 2 (ifna2, interferon …
Matched Description: … [L44381,L44431] BCG-unresponsive NMIBC has a high recurrence and is notably difficult to treat. ... Compared to [pembrolizumab], a smaller proportion of patients experienced grade 3-4 adverse events (4% ... across the urothelium and promotes the transduction of IFNα2b. …
Matched Categories: … Cellular and Gene Therapy ... Antineoplastic cell and gene therapy ... Antineoplastic and Immunomodulating Agents …

Teriparatide

Teriparatide is a recombinant parathyroid hormone (PTH) analog and a potent osteoanabolic agent. It is made up of the first amino(N)-terminal 34 amino acids of the human PTH. First approved in the United States in November 2002 and in Europe in April 2003, teriparatide makes the first approved drug in...
Approved
Investigational
Matched Description: … Teriparatide is a recombinant parathyroid hormone (PTH) analog and a potent osteoanabolic agent. ... [A251395] First approved in the United States in November 2002 and in Europe in April 2003,[A251400] ... teriparatide makes the first approved drug in a new category of osteoporosis therapy called anabolic …
Matched Categories: … Sex Hormones and Insulins ... Amino Acids, Peptides, and Proteins ... Parathyroid Hormones and Analogues ... Calcium-Regulating Hormones and Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Doconexent

A mixture of fish oil and primrose oil, doconexent is used as a high-docosahexaenoic acid (DHA) supplement. DHA is a 22 carbon chain with 6 cis double bonds with anti-inflammatory effects. It can be biosythesized from alpha-linolenic acid or commercially manufactured from microalgae. It is an omega-3 fatty acid and...
Approved
Investigational
Matched Synonyms: … 22:6(n-3) …
Matched Description: … It is an omega-3 fatty acid and primary structural component of the human brain, cerebral cortex, skin ... A mixture of fish oil and primrose oil, doconexent is used as a high-docosahexaenoic acid (DHA) supplement ... , and retina thus plays an important role in their development and function. …
Matched Mixtures name: … VemaVite-PRx 2 with Fish-Based DHA ... Tricare Prenatal 2-part Daily Prenatal Vitamin System ... Animi-3 …
Matched Categories: … Fatty Acids, Omega-3 …

Pimecrolimus

Pimecrolimus is an immunomodulating agent that was first marketed by Novartis under the trade name Elidel. It is now promoted in Canada by Galderma since early 2007. It is currently available as a topic cream used in the treatment of atopic dermatitis (eczema).
Approved
Investigational
Matched Iupac: … (1R,9S,12S,13R,14S,17R,18E,21S,23S,24R,25S,27R)-12-[(1E)-1-[(1R,3R,4S)-4-chloro-3-methoxycyclohexyl]prop ... -1-en-2-yl]-17-ethyl-1,14-dihydroxy-23,25-dimethoxy-13,19,21,27-tetramethyl-11,28-dioxa-4-azatricyclo …
Matched Description: … It is currently available as a topic cream used in the treatment of atopic dermatitis (eczema). …
Matched Categories: … Skin and Mucous Membrane Agents …

Alectinib

Alectinib is a second generation oral drug that selectively inhibits the activity of anaplastic lymphoma kinase (ALK) tyrosine kinase. It is specifically used in the treatment of non-small cell lung cancer (NSCLC) expressing the ALK-EML4 (echinoderm microtubule-associated protein-like 4) fusion protein that causes proliferation of NSCLC cells. Inhibition of ALK...
Approved
Investigational
Matched Synonyms: … 9-ethyl-6,6-dimethyl-8-[4-(morpholin-4-yl)piperidin-1-yl]-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3- …
Matched Iupac: … 9-ethyl-6,6-dimethyl-8-[4-(morpholin-4-yl)piperidin-1-yl]-11-oxo-5H,6H,11H-benzo[b]carbazole-3-carbonitrile …
Matched Description: … Inhibition of ALK prevents phosphorylation and subsequent downstream activation of STAT3 and AKT resulting ... Alectinib is a second generation oral drug that selectively inhibits the activity of anaplastic lymphoma ... Approved under accelerated approval in 2015, alectinib is indicated for use in patients who have progressed …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Heterocyclic Compounds, 3-Ring ... Antineoplastic and Immunomodulating Agents ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …

Diflorasone

Diflorasone is a topical corticosteroid used to treat itching and inflammation of the skin.
Approved
Matched Iupac: … -1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one ... (1R,2S,3aS,3bS,5S,9aS,9bR,10S,11aS)-5,9b-difluoro-1,10-dihydroxy-1-(2-hydroxyacetyl)-2,9a,11a-trimethyl …
Matched Description: … Diflorasone is a topical corticosteroid used to treat itching and inflammation of the skin. …
Matched Categories: … Hormones, Hormone Substitutes, and Hormone Antagonists …

Diphenylguanidine

Diphenylguanidine is a complexing agent used in the detection of metals and organic bases and used as an accelerator in the vulcanization of rubber. It is found in some rubber products. It is also a dermatological sensitizer and allergen. Sensitivity to diphenylguanidine may be identified with a clinical patch test.
Approved
Experimental
Matched Description: … It is also a dermatological sensitizer and allergen. ... Diphenylguanidine is a complexing agent used in the detection of metals and organic bases and used as ... Sensitivity to diphenylguanidine may be identified with a clinical patch test. …
Displaying drugs 276 - 300 of 5024 in total