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Displaying drugs 3026 - 3050 of 15253 in total
Withdrawn from the Canadian, US, and UK markets in 1963 due to interactions with food products containing tyrosine.
Approved
Withdrawn
Matched Synonyms: … 2-(2-(Benzylcarbamoyl)ethyl)hydrazide isonicotinic acid ... 2-(2-(Benzylcarbamyl)ethyl)hydrazide isonicotinic acid ... Isonicotinic acid 2-((2-benzylcarbamoyl)ethyl)hydrazide …
Matched Description: … Withdrawn from the Canadian, US, and UK markets in 1963 due to interactions with food products containing …
Cilastatin is an inhibitor of renal dehydropeptidase, an enzyme responsible for both the metabolism of thienamycin beta-lactam antibiotics as well as conversion of leukotriene D4 to leukotriene E4. Since the antibiotic, imipenem, is one such antibiotic that is hydrolyzed by dehydropeptidase, cilastatin is used in combination with imipenem to prevent...
Approved
Investigational
Matched Synonyms: … (L)-7-(2-Amino-2-carboxy-ethylsulfanyl)-2-[(2,2-dimethyl-cyclopropanecarbonyl)-amino]-hept-2-enoic acid ... (R)-2-Amino-2-carboxy-ethylsulfanyl)-2-[((S)-2,2-dimethyl-cyclopropanecarbonyl)-amino]-hept-2-enoic acid
Matched Iupac: … )-7-{[(2R)-2-amino-2-carboxyethyl]sulfanyl}-2-{[(1S)-2,2-dimethylcyclopropyl]formamido}hept-2-enoic acid
Matched Mixtures name: … Imipenem and Cilastatin ... Imipenem and Cilastatin ... Imipenem and Cilastatin …
Matched Categories: … imipenem and cilastatin ... imipenem, cilastatin and relebactam …
Camphor is a bicyclic monoterpene ketone found widely in plants, especially Cinnamomum camphora. It is used topically as a skin antipruritic and as an anti-infective agent. When ingested, camphor has a rapid onset of toxic effects, and camphorated oil is the product most often responsible for its toxicity. The FDA...
Approved
Withdrawn
Matched Description: … It is used topically as a skin antipruritic and as an anti-infective agent. ... When ingested, camphor has a rapid onset of toxic effects, and camphorated oil is the product most often ... The FDA ruled that camphorated oil could not be marketed in the United States and that no product could …
Matched Mixtures name: … Jack and Jill Rub ... Dermoplex Bite and Sting Cream ... Chest Rub and Cough Suppressant …
Matched Categories: … Basic Lotions and Liniments ... Antipruritics and Local Anesthetics …
Matched Products: … Joints and Muscles Pain Relieving ... Muscle and Joint HRX Pain Relieving ... Earths Care Muscle and Joint Rub …
Capsicum (Chili pepper) allergenic extract is used in allergenic testing.
Approved
Matched Mixtures name: … Zaxs Aches and Pain …
Matched Products: … SinolM Fast Allergy and Sinus Relief All-Natural Nasal …
Carbetocin is a drug used to control postpartum hemorrhage, bleeding after giving birth. It is an analogue of oxytocin, and its action is similar to that of oxytocin -- it causes contraction of the uterus.
Approved
Investigational
Matched Synonyms: … 1-butanoic acid-2-(O-methyl-L-tyrosine)-1-carbaoxytocin ... 1-butyric acid-2-(3-(p-methoxyphenyl)-L-alanine)oxytocin …
Matched Description: … It is an analogue of oxytocin, and its action is similar to that of oxytocin -- it causes contraction …
Matched Categories: … Pituitary and Hypothalamic Hormones and Analogues ... Oxytocin and Analogues ... Sex Hormones and Insulins ... Amino Acids, Peptides, and Proteins ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Propylparaben is used in allergenic testing.
Approved
Experimental
Matched Synonyms: … 4-Hydroxybenzoic acid propyl ester ... 4-Hydroxybenzoic acid, propyl ester ... p-Hydroxybenzoic acid propyl ester …
Adenosine phosphate, or adenylic acid, is an adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position. Adenosine phosphate was withdrawn by the FDA since it was considered neither safe nor effective for its intended uses as a vasodilator and an anti-inflammatory.
Approved
Investigational
Nutraceutical
Withdrawn
Matched Synonyms: … 5'-Adenylic acid ... Adenylic acid ... Adenosine-5'-monophosphoric acid
Matched Iupac: … {[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acid
Matched Description: … Adenosine phosphate, or adenylic acid, is an adenine nucleotide containing one phosphate group esterified ... by the FDA since it was considered neither safe nor effective for its intended uses as a vasodilator and
Matched Categories: … Nucleic Acids, Nucleotides, and Nucleosides …
Alcohol use disorder is responsible for a large worldwide burden of morbidity, premature mortality, and economic consequences resulting from accidents, violence, incarceration, decreased productivity, and increased healthcare spending. Acamprosate, also known by the brand name Campral, is a drug used for the maintenance of alcohol abstinence. It is a structural...
Approved
Investigational
Matched Synonyms: … 3-Acetamido-1-propanesulfonic acid
Matched Iupac: … 3-acetamidopropane-1-sulfonic acid
Matched Description: … It is a structural analogue of the neurotransmitter γ-aminobutyric acid (GABA). ... Alcohol use disorder is responsible for a large worldwide burden of morbidity, premature mortality, and ... economic consequences resulting from accidents, violence, incarceration, decreased productivity, and
Approved
Matched Synonyms: … L-Ascorbic acid, iron complex …
Matched Categories: … Diet, Food, and Nutrition ... Blood and Blood Forming Organs …
Meropenem is a broad-spectrum carbapenem antibiotic. It is active against Gram-positive and Gram-negative bacteria. Meropenem exerts its action by penetrating bacterial cells readily and interfering with the synthesis of vital cell wall components, which leads to cell death. In August 2017, a combination antibacterial therapy under the market name vabomere...
Approved
Investigational
Matched Synonyms: … pyrrolidin-3-yl]thio}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
Matched Iupac: … pyrrolidin-3-yl]sulfanyl}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
Matched Description: … Vabomere consists of meropenem and [DB12107] and is intravenously admininstered. ... It is active against Gram-positive and Gram-negative bacteria. ... Meropenem exerts its action by penetrating bacterial cells readily and interfering with the synthesis …
Matched Categories: … meropenem and vaborbactam …
Matched Products: … Meropenem and Sodium Chloride ... Meropenem for Injection USP and Sodium Chloride Injection USP …
Ataluren is a novel, orally administered drug that targets nonsense mutations. Ataluren is approved for use by the European Medicines Agency to treat Duchenne Muscular Dystrophy in patients aged 5 years and older who are able to walk. More specifically, ataluren is used in the small group of patients whose...
Approved
Investigational
Matched Synonyms: … 3-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]benzoic acid
Matched Iupac: … 3-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]benzoic acid
Matched Description: … use by the European Medicines Agency to treat Duchenne Muscular Dystrophy in patients aged 5 years and ... This drug does not yet have approval by the US Food and Drug Administration or by Health Canada for any …
An oral retinoid effective in the treatment of psoriasis. It is the major metabolite of etretinate with the advantage of a much shorter half-life when compared with etretinate.
Approved
Matched Synonyms: … (all-E)-9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic acid ... all-trans-3,7-Dimethyl-9-(4-methoxy-2,3,6-trimethylphenyl)-2,4,6,8-nonatetraenoic acid
Matched Iupac: … (2E,4E,6E,8E)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoic acid
Matched Categories: … Skin and Mucous Membrane Agents …
Bismuth subsalicylate is an antacid and anti-diarrheal agent. Exhibiting antibacterial and gastroprotective properties, bismuth subsalicylate is an insoluble salt of salicylic acid linked to trivalent bismuth cation. Each molecule of bismuth subsalicylate contains 58% bismuth and 42% salicylate by weight. Bismuth subsalicylate has been around for over 100 years: it...
Approved
Vet approved
Matched Description: … of [salicylic acid] linked to trivalent [bismuth cation]. ... Bismuth subsalicylate is an antacid and anti-diarrheal agent. ... to relieve nausea, diarrhea, and gastrointestinal discomfort. …
Matched Mixtures name: … Bismuth Subsalicylate/Metronidazole/Tetracycline Hydrochloride ... Pepto-Bismol and Pepto-Bismol To Go ... Pepto-Bismol and Pepto-Bismol To Go …
Matched Categories: … Antacids and Adsorbents …
Matched Products: … Up and Up Stomach Relief ... Up and Up Digestive Relief ... Foster and Thrive Stomach Relief …
A trihydroxy sugar alcohol that is an intermediate in carbohydrate and lipid metabolism.
Approved
Investigational
Matched Description: … A trihydroxy sugar alcohol that is an intermediate in carbohydrate and lipid metabolism. …
Matched Mixtures name: … Glycerin, Lidocaine, Petrolatum, and Phenylephrine Hydrochloride ... 2% Salicylic Acid FACIAL CLEANSER ... Essential Solution Hyaluronic Acid Mask Sheet …
Matched Categories: … Alimentary Tract and Metabolism ... Basic Ointments and Protectants ... Other Cold and Cough Preparations …
Matched Products: … Aqua Collagen Hyaluronic Acid Hydro Mask ... BOTANIC HEAL boH Air Jet Daily Mask Hyaluronic Acid ... ATONO2 Oxygen Baby Bath and
Captopril is a potent, competitive inhibitor of angiotensin-converting enzyme (ACE), the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS). Captopril may be used in the treatment of hypertension.
Approved
Matched Synonyms: … (2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid
Matched Iupac: … (2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid
Matched Description: … ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS …
Matched Mixtures name: … Captopril and Hydrochlorothiazide ... Captopril and Hydrochlorothiazide ... Captopril and Hydrochlorothiazide …
Matched Categories: … ACE Inhibitors and Diuretics ... captopril and diuretics ... Amino Acids, Peptides, and Proteins …
Naloxone is an opioid antagonist medication used to block or reverse the effects of opioid drugs, particularly within the setting of drug overdoses which are rapidly becoming a leading cause of death worldwide. More specifically, naloxone has a high affinity for μ-opioid receptors, where it acts as an inverse agonist,...
Approved
Vet approved
Matched Description: … , and even death. ... Frequently also carried by medical and emergency personnel and at events known to be associated with ... [A234589] It's important to note that naloxone only works on opioid receptors within the body, and is …
Matched Mixtures name: … Pentazocine Hydrochloride and Naloxone Hydrochloride ... Pentazocine Hydrochloride and Naloxone Hydrochloride ... Buprenorphine Hydrochloride and Naloxone Hydrochloride Dihydrate …
Matched Salts name: … Naloxone hydrochloride ... Naloxone hydrochloride dihydrate …
Matched Categories: … Alimentary Tract and Metabolism ... tilidine and naloxone ... oxycodone and naloxone ... pentazocine and naloxone ... hydromorphone and naloxone …
Matched Products: … Naloxone Hydrochloride ... NALOXONE HYDROCHLORIDE ... Naloxone Hydrochloride Fine …
Gluconolactone is a naturally-occurring food additive used as a sequestrant, an acidifier, or a curing, pickling, or leavening agent. It is a cyclic ester of D-gluconic acid. Pure gluconolactone is a white odorless crystalline powder.
Approved
Experimental
Matched Synonyms: … Gluconic acid lactone ... D-gluconic acid delta-lactone …
Matched Description: … It is a cyclic ester of D-gluconic acid. Pure gluconolactone is a white odorless crystalline powder. …
Benazepril, brand name Lotensin, is a medication used to treat high blood pressure (hypertension), congestive heart failure, and chronic renal failure[A838,A837]. Upon cleavage of its ester group by the liver, benazepril is converted into its active form benazeprilat, a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor .
Approved
Investigational
Matched Iupac: … [(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]acetic acid
Matched Description: … Lotensin, is a medication used to treat high blood pressure (hypertension), congestive heart failure, and
Matched Mixtures name: … Benazepril Hydrochloride and Hydrochlorothiazide ... Benazepril Hydrochloride and Hydrochlorothiazide ... Benazepril Hydrochloride and Hydrochlorothiazide …
Matched Salts name: … Benazepril hydrochloride
Matched Categories: … ACE Inhibitors and Diuretics ... benazepril and diuretics ... benazepril and amlodipine ... ACE Inhibitors and Calcium Channel Blockers …
Matched Products: … Benazepril Hydrochloride ... Benazepril hydrochloride
Ferrous asparto glycinate is an iron-amino acid chelate. It is available as a dietary supplement used in the treatment of iron deficiency and iron deficiency anemia.
Approved
Matched Description: … Ferrous asparto glycinate is an iron-amino acid chelate. ... It is available as a dietary supplement used in the treatment of iron deficiency and iron deficiency …
Matched Mixtures name: … Iron Fumarate and Aspartate, Glycinate, Ascorbic Calcium, Vitamin B12, Folic Acid, Calcium Threonate ... Iron Aspartate Glycinate and Polysaccharide Complex, Ascorbic Calcium, Vitamin B12, Folic Acid, Calcium ... and Succinic Acid
Promethazine, originally known as 3,277 R.P., is an N-dimethylaminopropyl derivative of phenothiazine that was developed in France in 1946. Promethazine antagonizes a variety of receptors, allowing it to be used for a number of indications including allergic reactions, pain, sedation, nausea, and vomiting.[A189907,A190153,A190159,A190150,A190171] Promethazine was granted FDA approval before 29...
Approved
Investigational
Matched Description: … allowing it to be used for a number of indications including allergic reactions, pain, sedation, nausea, and
Matched Mixtures name: … Promethazine Hydrochloride and Phenylephrine Hydrochloride ... Meperidine Hydrochloride and Promethazine Hydrochloride ... Promethazine Hydrochloride and Phenylephrine Hydrochloride
Matched Salts name: … Promethazine hydrochloride
Matched Categories: … Acid Reducers ... prednisolone and promethazine ... Miscellaneous Anxiolytics Sedatives and Hypnotics …
Matched Products: … Promethazine Hydrochloride ... Promethazine hydrochloride ... Promethazine Hydrochloride Injection USP …
Ambrisentan is an orally active selective type A endothelin receptor antagonist indicated for the treatment of pulmonary arterial hypertension. It is approved in Europe, Canada and the United States for use as a single agent to improve exercise ability and delay clinical worsening. In addition, it is approved in the...
Approved
Investigational
Matched Synonyms: … (2S)-2-[(4,6-dimethylpyrimidin-2-yl)oxy]-3-methoxy- 3,3-diphenylpropanoic acid
Matched Iupac: … (2S)-2-[(4,6-dimethylpyrimidin-2-yl)oxy]-3-methoxy-3,3-diphenylpropanoic acid
Matched Description: … ability and delay clinical worsening. ... It is approved in Europe, Canada and the United States for use as a single agent to improve exercise ... Patients studied displayed symptoms and etiologies predominantly of WHO Functional Class II-III. …
Matched Categories: … ambrisentan and tadalafil …
Elafibranor is a dual peroxisome proliferator-activated receptor (PPAR) α and β/δ agonist. On June 10, 2024, elafibranor was granted accelerated approval by the FDA for the treatment of primary biliary cholangitis (PBC).
Approved
Investigational
Matched Synonyms: … PROPANOIC ACID, 2-(2,6-DIMETHYL-4-((1E)-3-(4-(METHYLTHIO)PHENYL)-3-OXO-1-PROPEN-1-YL)PHENOXY)- ... PROPANOIC ACID, 2-(2,6-DIMETHYL-4-(3-(4-(METHYLTHIO)PHENYL)-3-OXO-1-PROPEN-1-YL)PHENOXY)-2-METHYL- …
Matched Iupac: … 2-{2,6-dimethyl-4-[(1E)-3-[4-(methylsulfanyl)phenyl]-3-oxoprop-1-en-1-yl]phenoxy}-2-methylpropanoic acid
Matched Description: … Elafibranor is a dual peroxisome proliferator-activated receptor (PPAR) α and β/δ agonist. …
Matched Categories: … Bile and Liver Therapy ... Alimentary Tract and Metabolism …
A broad-spectrum 6-fluoronaphthyridinone antibacterial agent (fluoroquinolones) structurally related to nalidixic acid.
Approved
Investigational
Matched Synonyms: … 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8-naphthyridine-3-carboxylic acid ... 1-Ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid
Matched Iupac: … 1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid
Matched Description: … broad-spectrum 6-fluoronaphthyridinone antibacterial agent (fluoroquinolones) structurally related to nalidixic acid
Matched Categories: … Metabolic Side Effects of Drugs and Substances …
Guaiacol is an agent thought to have disinfectant properties and used as an expectorant. Guaiacol is a phenolic natural product first isolated from Guaiac resin and the oxidation of lignin. Guaiacol is also present in wood smoke, as a product of pyrolysis of lignin. Guaiacol has been found in the...
Approved
Matched Synonyms: … Pyroguaiac acid
Matched Description: … Guaiacol is an agent thought to have disinfectant properties and used as an expectorant. ... Guaiacol has been found in the urine of patients with neuroblastoma and pheochromocytoma. ... Guaiacol is a phenolic natural product first isolated from Guaiac resin and the oxidation of lignin. …
Matched Salts name: … Guaiacol hydrochloride
Bupivacaine is a widely used local anesthetic agent.
Approved
Investigational
Matched Mixtures name: … Bupivacaine Hydrochloride and Epinephrine ... Bupivacaine Hydrochloride and Epinephrine ... Bupivacaine Hydrochloride and Epinephrine …
Matched Salts name: … Bupivacaine hydrochloride ... Bupivacaine hydrochloride anhydrous …
Matched Categories: … bupivacaine and meloxicam …
Matched Products: … Bupivacaine Hydrochloride ... Bupivicaine Hydrochloride ... Bupivacaine hydrochloride
Displaying drugs 3026 - 3050 of 15253 in total