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Displaying drugs 301 - 325 of 11636 in total

Enoxacin

A broad-spectrum 6-fluoronaphthyridinone antibacterial agent (fluoroquinolones) structurally related to nalidixic acid.
Approved
Investigational
Matched Description: … A broad-spectrum 6-fluoronaphthyridinone antibacterial agent (fluoroquinolones) structurally related …

Tetracosactide

Tetracosactide (also known as Cosyntropin) is a synthetic peptide that is identical to the 24-amino acid segment (sequence: SYSMEHFRWGKPVGKKRRPVKVYP) at the N-terminal of adrenocorticotropic hormone. ACTH (1-24), a segment similar in all species, contains the biological activity that stimulates production of corticosteroids in the adrenal cortex. Tetracosactide exhibits the same...
Approved
Matched Description: … The complex results in a product whose absorption in man is effected over a longer period of time as ... Tetracosactide (also known as Cosyntropin) is a synthetic peptide that is identical to the 24-amino acid ... ACTH (1-24), a segment similar in all species, contains the biological activity that stimulates production …

Aceclidine

Aceclidine has been marketed in Europe but has not been used clinically in the United States. It is used in the treatment of open-angle glaucoma and is a parasympathomimetic agent.
Approved
Matched Description: … It is used in the treatment of open-angle glaucoma and is a parasympathomimetic agent. …

Anacaulase

Anacaulase (anacaulase-bcdb) is a mixture of proteolytic enzymes extracted from the stems of pineapple plants (Ananas comosus [L.] Merr.). It is mostly composed (80-95% w/w) of proteins such as stem bromelain, ananain, jacalin-like lectin, bromelain inhibitors, and phytocystatin inhibitor, as well as saccharides, as both free monosaccharides and the N-linked...
Approved
Investigational
Matched Description: … Anacaulase (anacaulase-bcdb) is a mixture of proteolytic enzymes extracted from the stems of pineapple ... Removing eschar (a process also known as debridement) through surgical procedures can lead to significant …

Avanafil

Avanafil is a phosphodiesterase-5 (PDE5) inhibitor used in the treatment of erectile dysfunction. In comparison with other drugs of the same class, it shows greater selectivity for PDE5 over PDE6 than both sildenafil and vardenafil but less selectivity than tadalafil, suggesting a relatively lower risk of visual disturbances associated with...
Approved
Matched Description: … Avanafil is a phosphodiesterase-5 (PDE5) inhibitor used in the treatment of erectile dysfunction. ... over PDE6 than both [sildenafil] and [vardenafil] but less selectivity than [tadalafil], suggesting a …

Enalapril

Enalapril is a prodrug belonging to the angiotensin-converting enzyme (ACE) inhibitor drug class that works on the renin-angiotensin-aldosterone system, which is responsible for the regulation of blood pressure and fluid and electrolyte homeostasis. Enalapril is an orally-active and long-acting nonsulphydryl antihypertensive agent that suppresses the renin-angiotensin-aldosterone system to lower blood...
Approved
Vet approved
Matched Description: … It was developed from a targeted research programmed using molecular modelling. ... Enalapril is a prodrug belonging to the angiotensin-converting enzyme (ACE) inhibitor drug class that ... [A18459] Being a prodrug, enalapril is rapidly biotransformed into its active metabolite, [enalaprilat …

Manganese cation

Manganese is a transition metal that was first described in the 19th and 20th centuries. It is environmentally abundant, being the fifth most abundant metal and the twelfth most abundant element overall on Earth.[A263657, A263667] Manganese intake primarily occurs through the diet, as it is found at low levels in...
Approved
Nutraceutical
Matched Description: … Manganese is a transition metal that was first described in the 19th and 20th centuries. ... [A263687, A263662] In humans, manganese regulates several physiological processes by acting as a cofactor …
Matched Mixtures name: … One A Day Tab ... ONE A DAY TABLET ... A/o-26 - Caplet …

Colestipol

Bile acid sequestrants like colestipol have been in use since the 1970s.[FDA Label, F4555, F4567, L6262] And even though such an agent may very well be useful in reducing elevated cholesterol levels and decreasing the risk for atherosclerotic vascular disease due to hypercholesterolemia, colestipol is still generally only employed as...
Approved
Matched Categories: … Compounds used in a research, industrial, or household setting …

Moxetumomab pasudotox

CD22 is a lineage-restricted B-cell antigen that is expressed solely in on B-chronic lymphocytic leukemia, hairy cell leukemia, acute lymphocytic leukemiathe and Burkitt's lymphoma. The predecessor of Moxetumab pasudotox (MxP), named BL22, was first created based on the antibody RFB4 which specifically binds to CD22. This antibody was used to...
Approved
Investigational
Matched Description: … This antibody was used to generate a recombinant immunotoxin in which a stabilized Fv segment by a disulfide ... CD22 is a lineage-restricted B-cell antigen that is expressed solely in on B-chronic lymphocytic leukemia ... bond is fused to the _Pseudomonas_ exotoxin A (PE38) which does not have the cell-binding portion. …

Carboprost tromethamine

A nonsteroidal abortifacient agent that is effective in both the first and second trimesters of pregnancy.
Approved
Matched Description: … A nonsteroidal abortifacient agent that is effective in both the first and second trimesters of pregnancy …

Chloroxylenol

Chloroxylenol, or para-chloro-meta-xylenol (PCMX), is an antiseptic and disinfectant agent used for skin disinfection and surgical instruments. It is found in antibacterial soaps, wound-cleansing applications, and household antiseptics. The halophenol is shown to be most effective against Gram positive bacteria where it disrupts the cell wall due to its phenolic...
Approved
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Germ A Stat …

Levocetirizine

Levocetirizine is a selective histamine H1 antagonist used to treat a variety of allergic symptoms.[A181748,A181790,L7694] It is the R enantiomer of cetirizine. Levocetirizine has greater affinity for the histamine H1 receptor than cetirizine. Levocetirizine was granted FDA approval in 1995.
Approved
Matched Description: … Levocetirizine is a selective histamine H1 antagonist used to treat a variety of allergic …

Atogepant

Atogepant is an oral antagonist of calcitonin gene-related peptide (CGRP) receptors indicated for the prevention of episodic migraine headaches. It was developed by AbbVie and received FDA approval under the brand name Qulipta in September 2021. While its approval was predated by two other members of the same drug family,...
Approved
Investigational
Matched Description: … family of drugs, including atogepant, are comparatively well-tolerated[A189207,L38739] and may provide a …

Castor oil

Castor oil is a vegetable oil obtained by pressing the seeds of the castor oil plant (Ricinus communis L.) mainly cultivated in India, South America, Africa, and China. Castor oil is a rich source of DB02955, which represents up to 90% of the total castor oil content. It also consists...
Approved
Investigational
Nutraceutical
Vet approved
Matched Description: … [DB02955] has a hydroxyl group that provides a functional group location for various chemical reactions ... , making it a favourable substance in industrial applications [A31170]. ... Castor oil is a vegetable oil obtained by pressing the seeds of the castor oil plant (_Ricinus communis …

Warfarin

Warfarin is an anticoagulant drug normally used to prevent blood clot formation as well as migration. Although originally marketed as a pesticide (d-Con, Rodex, among others), Warfarin has since become the most frequently prescribed oral anticoagulant in North America. Warfarin has several properties that should be noted when used medicinally,...
Approved
Matched Description: … Although originally marketed as a pesticide (d-Con, Rodex, among others), Warfarin has since become the …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C18 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic Index …

Gadopentetic acid

A complex of gadolinium with a chelating agent, diethylenetriamine penta-acetic acid (DTPA see pentetic acid), that is given to enhance the image in cranial and spinal MRIs. (From Martindale, The Extra Pharmacopoeia, 30th ed, p706)
Approved
Matched Description: … A complex of gadolinium with a chelating agent, diethylenetriamine penta-acetic acid (DTPA see pentetic …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Alverine

Alverine is a smooth muscle relaxant used to relieve cramps or spasms of the stomach and intestines. It is therefore useful in treating irritable bowel syndrome (IBS) and similar conditions. It can also be used to help relieve period pain.
Approved
Investigational
Matched Description: … Alverine is a smooth muscle relaxant used to relieve cramps or spasms of the stomach and intestines. …

Erdafitinib

In early April of 2019, the US FDA approved Janssen Pharmaceutical Companies' brand name Balversa (erdafitinib) as the first-ever fibroblast growth factor receptor (FGFR) kinase inhibitor indicated for patients with locally advanced or metastatic urothelial carcinoma, with susceptible FGFR3 or FGFR2 genetic alterations, that has progressed during or following platinum-containing...
Approved
Investigational
Matched Description: … the same time, the FDA also approved the therascreen FGFR RGQ RT-PCR Kit (Qiagen) for utilization as a ... cancer, which demonstrates the development of more personalized and precise medicines tailoring to a ... statistically the fourth most common kind of cancer in the world, the introduction of erdafitinib offers a …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …

Triprolidine

First generation histamine H1 antagonist used in allergic rhinitis; asthma; and urticaria. It is a component of cough and cold medicines. It may cause drowsiness.
Approved
Matched Description: … It is a component of cough and cold medicines. It may cause drowsiness. …
Matched Mixtures name: … Ed-A-hist Pse ... A-FERIN DECO ŞURUP, 100 ML ... A-FERIN DECO TABLET, 20 ADET …

Tedizolid

Drug-resistant bacteria, such as methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus faecium, and penicillin-resistant Streptococcus penumoniae, represent a massive public health threat.[A199086, A199131] Tedizolid is a member of the oxazolidinone class of antibiotics, which includes the previously approved linezolid and is generally effective against multidrug-resistant Gram-positive bacteria. Tedizolid is indicated for the...
Approved
Investigational
Matched Description: … [A199086, A199131] Tedizolid is a member of the oxazolidinone class of antibiotics, which includes the ... vancomycin-resistant _Enterococcus faecium_, and penicillin-resistant _Streptococcus penumoniae_, represent a ... This product is currently available as both an oral tablet and as a powder for intravenous injection. …
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …

Yohimbine

A plant alkaloid with alpha-2-adrenergic blocking activity. Yohimbine has been used as a mydriatic and in the treatment of impotence. It is also alleged to be an aphrodisiac.
Approved
Investigational
Vet approved
Matched Description: … A plant alkaloid with alpha-2-adrenergic blocking activity. ... Yohimbine has been used as a mydriatic and in the treatment of impotence. …

Dapagliflozin

Dapagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor, and it was the first SLGT2 inhibitor to be approved. indicated for managing diabetes mellitus type 2. When combined with diet and exercise in adults, dapagliflozin helps to improve glycemic control by inhibiting glucose reabsorption in the proximal tubule of the nephron...
Approved
Matched Description: … Dapagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor, and it was the first SLGT2 inhibitor …

Alatrofloxacin

Alatrofloxacin is a fluoroquinolone antibiotic developed by Pfizer, delivered as a mesylate salt. It was withdrawn from the U.S. market in 2001.
Approved
Withdrawn
Matched Description: … Alatrofloxacin is a fluoroquinolone antibiotic developed by Pfizer, delivered as a mesylate salt. …

Tacrine

A centerally active cholinesterase inhibitor that has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and in the treatment of Alzheimer's disease and other central nervous system disorders. Tacrine has been discontinued for the United States market.
Approved
Investigational
Withdrawn
Matched Description: … A centerally active cholinesterase inhibitor that has been used to counter the effects of muscle relaxants ... , as a respiratory stimulant, and in the treatment of Alzheimer's disease and other central nervous system …

Isocarboxazid

Isocarboxazid has the formula 1-benzyl-2-(5-methyl-3-isoxazolylcarbonyl)hydrazine-isocarboxazid. It is a monoamine oxidase inhibitor. It is used in the treatment of major depression, dysthymic disorder, atypical disorder, panic disorder and the phobic disorders. It was first introduced by Roche pharmaceuticals, further developed by Validus pharms Inc and first FDA approved as a prescription...
Approved
Matched Description: … It is a monoamine oxidase inhibitor. ... introduced by Roche pharmaceuticals, further developed by Validus pharms Inc and first FDA approved as a …
Matched Categories: … Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates …
Displaying drugs 301 - 325 of 11636 in total