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Displaying drugs 301 - 325 of 15549 in total
Acromegaly is a disorder caused by excess growth hormone (GH), increasing the growth of body tissues and causing metabolic dysfunction. In most cases, it results from an anterior pituitary growth hormone-releasing tumor. Typically, the feet, hands, and face grow abnormally large; organomegaly and insulin resistance may also occur. Acromegaly is...
Approved
Investigational
Matched Description: … [L14513] In the past, octreotide has been administered solely by injection. ... [L14501] In most cases, it results from an anterior pituitary growth hormone-releasing tumor. ... Acromegaly is a life-threatening disease requiring life-long management. …
Matched Salts cas: … 135467-16-2
Matched Products: … SANDOSTATIN LAR FOR INJECTION 10 mg ... SANDOSTATIN LAR FOR INJECTION 20 mg ... SANDOSTATIN LAR FOR INJECTION 30 mg …
Tovorafenib is a selective type II RAF kinase inhibitor with anti-tumour activity. It was granted accelerated approval by the FDA, making it the first FDA approval of a systemic therapy for the treatment of pediatric low-grade glioma, with BRAF rearrangements. BRAF oncogenic mutations in cancers drive dysregulated cell growth, proliferation,...
Approved
Investigational
Matched Synonyms: … ]carbonyl]-2-thiazolyl]ethyl]- ... 6-Amino-5-chloro-N-((1R)-1-(5-(((5-chloro-4-(trifluoromethyl)-2-pyridinyl)amino)carbonyl)-2-thiazolyl ... 4-Pyrimidinecarboxamide, 6-amino-5-chloro-N-[(1R)-1-[5-[[[5-chloro-4-(trifluoromethyl)-2-pyridinyl]amino …
Matched Iupac: … 6-amino-5-chloro-N-[(1R)-1-(5-{[5-chloro-4-(trifluoromethyl)pyridin-2-yl]carbamoyl}-1,3-thiazol-2-yl) …
Matched Description: … therapy for the treatment of pediatric low-grade glioma, with BRAF rearrangements. ... [L50587] BRAF oncogenic mutations in cancers drive dysregulated cell growth, proliferation, and differentiation ... Tovorafenib is a selective type II RAF kinase inhibitor with anti-tumour activity. …
Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is...
Approved
Matched Synonyms: … (R)-4-(2-amino-1-hydroxyethyl)-1,2-benzenediol ... 4-[(1R)-2-Amino-1-hydroxyethyl]-1,2-benzenediol …
Matched Iupac: … 4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol …
Matched Description: … It is also found in plants and is used pharmacologically as a sympathomimetic. ... Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic ... principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in
Matched Mixtures name: … XYLONOR %3 NORADRENALINE ENJEKSIYONLUK SOLUSYON ICEREN KULLANIMA HAZIR 50 KARTUS …
Matched Categories: … Adrenergic beta-3 Receptor Agonists ... Adrenergic alpha-2 Receptor Agonists ... Adrenergic beta-2 Receptor Agonists …
Matched Products: … Norepinephrine Bitartrate In Sodium Chloride ... Norepinephrine Bitartrate In 5% Dextrose Injection ... N-EPI® 1mg/ml Concentrate for Solution for Infusion …
Dasatinib is an orally available multikinase inhibitor indicated for the treatment of Philadelphia chromosome (Ph)-positive leukemias.[A2224,L45171] Ph is a chromosomal abnormality found in patients with chronic myelogenous leukemia (CML) and acute lymphocytic leukemia (ALL), where the ABL tyrosine kinase and the breakpoint cluster region (BCR) gene transcribe the chimeric protein...
Approved
Investigational
Matched Synonyms: … N-(2-CHLORO-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3 …
Matched Iupac: … N-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3 …
Matched Description: … drug represents a therapeutic alternative for patients with cancers that have developed imatinib-resistance ... [A2224,L45171] Ph is a chromosomal abnormality found in patients with chronic myelogenous leukemia (CML ... [A11377,A33432] Dasatinib also inhibits a spectrum of kinases involved in cancer, including several SRC-family …
Matched Categories: … P-glycoprotein substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index ... Cytochrome P-450 CYP3A5 Substrates with a Narrow Therapeutic Index …
Phenylephrine is an alpha-1 adrenergic receptor agonist used to treat hypotension,[L9416,L9410] dilate the pupil, and induce local vasoconstriction. The action of phenylephrine, or neo-synephrine, was first described in literature in the 1930s. Phenylephrine was granted FDA approval in 1939.
Approved
Matched Synonyms: … l-(3-Hydroxyphenyl)-N-methylethanolamine …
Matched Iupac: … 3-[(1R)-1-hydroxy-2-(methylamino)ethyl]phenol …
Matched Description: … [A187370] The action of phenylephrine, or neo-synephrine, was first described in literature in the 1930s ... [A187376] Phenylephrine was granted FDA approval in 1939.[L9413] …
Matched Mixtures name: … Cold Medicine XL-3 for Children ... Cold and Flu All In One ... Doc in the Box All Day Supply …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Monoamine Oxidase A Substrates ... Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use ... Nasal Decongestants for Systemic Use …
Matched Products: … PHENYLALPHA SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 50MCG/ML ... Help I Have a Stuffy Nose ... Green Guard Allergy 2 Relief …
Technetium Tc 99m Mebrofenin is a diagnostic radiopharmaceutical composed of diisopropyl-iminodiacetic acid (DISIDA) attached to a technetium-99m ion. Following intravenous injection, single photon emission computer tomography (SPECT) imaging of the liver or gallbladder is performed using a gamma camera to detect the gamma rays emitted by the technetium-99m as it...
Approved
Matched Synonyms: … Bis(2-[[2-(3-bromo-2,4,6-trimethylanilino)-2-oxoethyl]-(carboxymethyl)amino]acetate) technetium …
Matched Iupac: … 2-({[(3-bromo-2,4,6-trimethylphenyl)carbamoyl]methyl}(carboxymethyl)amino)acetic acid technetium …
Matched Description: … Currently available within a sterile kit, Tc-99m Mebrofenin is indicated for imaging of the liver and ... attachment to mebrofenin as this molecule has high hepatic uptake and fast biliary excretion, resulting in ... acid (DISIDA) attached to a technetium-99m ion. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Melatonin is a biogenic amine that is found in animals, plants and microbes. Aaron B. Lerner of Yale University is credited for naming the hormone and for defining its chemical structure in 1958. In mammals, melatonin is produced by the pineal gland. The pineal gland is small endocrine gland, about...
Approved
Nutraceutical
Vet approved
Matched Synonyms: … N-[2-(5-methoxyindol-3-yl)ethyl]acetamide …
Matched Iupac: … N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide …
Matched Description: … A 2008 study found that unaffected parents of individuals with ASD also have lower melatonin levels, ... Lerner of Yale University is credited for naming the hormone and for defining its chemical structure ... Melatonin is a biogenic amine that is found in animals, plants and microbes. Aaron B. …
Matched Categories: … Compounds used in a research, industrial, or household setting ... Heterocyclic Compounds, 2-Ring …
Matched Products: … Mellozzan 2 mg Tabletten ... CIRCADIN 2 MG PROLONGED-RELEASE TABLETS ... Melatonin Bluefish 2 mg Retardtabletten …
Phentolamine is a reversible, non-selective alpha-adrenergic blocker that induces vasodilation. While initially introduced to the market for the treatment of hypertension, this clinical use was halted due to cardiovascular and gastrointestinal adverse effects with the prolonged use of large oral doses of phentolamine.[A261781, A261786] It has several therapeutic uses, including...
Approved
Matched Synonyms: … 3-((4,5-DIHYDRO-1H-IMIDAZOL-2-YLMETHYL)(4-METHYLPHENYL)AMINO)PHENOL ... 2-(N-(m-hydroxyphenyl)-p-toluidinomethyl)imidazoline …
Matched Iupac: … 3-{[(4,5-dihydro-1H-imidazol-2-yl)methyl](4-methylphenyl)amino}phenol …
Matched Description: … Phentolamine is a reversible, non-selective alpha-adrenergic blocker that induces vasodilation. ... While initially introduced to the market for the treatment of hypertension, this clinical use was halted …
Zoledronic acid, or CGP 42'446, is a third generation, nitrogen containing bisphosphonate similar to ibandronic acid, minodronic acid, and risedronic acid. Zoledronic acid is used to treat and prevent multiple forms of osteoporosis, hypercalcemia of malignancy, multiple myeloma, bone metastases from solid tumors, and Paget’s disease of bone.[L13712,L13715,L13721] Zoledronic acid...
Approved
Matched Synonyms: … (1-hydroxy-2-imidazol-1-ylethylidene)diphosphonic acid ... (1-hydroxy-2-(1H-imidazol-1-yl)ethylidene)bisphosphonic acid …
Matched Iupac: … [1-hydroxy-2-(1H-imidazol-1-yl)-1-phosphonoethyl]phosphonic acid …
Matched Description: … [L13712,L13715,L13721] Zoledronic acid was first described in the literature in 1994. ... Zoledronic acid, or CGP 42'446,[A203120] is a third generation, nitrogen containing bisphosphonate similar …
Matched Categories: … Drugs for Treatment of Bone Diseases …
Matched Products: … ZOLEDRONSAEURE F K 4MG/5ML ... ASZORA TRIO CA+D3 4MG/100 ... ASZORA TRIO CA+D3 4MG/5ML …
Idarucizumab is a humanized monoclonal antibody fragment (Fab) derived from an immunoglobulin G1 isotype molecule that binds to and inactivates the oral anticoagulant dabigatran, thereby reversing its anticoagulant effect. As a direct acting oral anticoagulant (DOAC), one of the risks associated with the use of dabigatran includes bleeding, espeically when...
Approved
Matched Description: … dabigatran-associated bleeding in life-threatening or surgically induced situations. ... Approved under the tradename Praxbind (FDA), idarucizumab is indicated for the emergency treatment of ... Idarucizumab is a humanized monoclonal antibody fragment (Fab) derived from an immunoglobulin G1 isotype …
Matched Products: … PRAXBİND 50 MG/ML ENJEKSİYONLUK/İNFÜZYONLUK ÇÖZELTİ, 2 ADET ... PRAXBIND Solution for Injection/Infusion 50 mg/ml ... PRAXBIND SOLUTION FOR INJECTION/INFUSION 50 MG/ML …
Diflunisal, a salicylate derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with pharmacologic actions similar to other prototypical NSAIAs. Diflunisal possesses anti-inflammatory, analgesic and antipyretic activity. Though its mechanism of action has not been clearly established, most of its actions appear to be associated with inhibition of prostaglandin synthesis via the...
Approved
Investigational
Matched Synonyms: … 2',4'-difluoro-4-hydroxy-3-biphenylcarboxylic acid ... 2-(hydroxy)-5-(2,4-difluorophenyl)benzoic acid …
Matched Iupac: … 2',4'-difluoro-4-hydroxy-[1,1'-biphenyl]-3-carboxylic acid …
Matched Description: … Diflunisal, a salicylate derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with pharmacologic ... Diflunisal is used to relieve pain accompanied with inflammation and in the symptomatic treatment of …
Matched Categories: … Non COX-2 selective NSAIDS …
A chelating agent (chelating agents) that sequesters a variety of polyvalent cations. It is used in pharmaceutical manufacturing and as a food additive.
Approved
Vet approved
Matched Synonyms: … 2,2',2'',2'''-(ethane-1,2-diyldinitrilo)tetraacetate …
Matched Iupac: … 2-({2-[bis(carboxymethyl)amino]ethyl}(carboxymethyl)amino)acetic acid …
Matched Description: … It is used in pharmaceutical manufacturing and as a food additive. ... A chelating agent (chelating agents) that sequesters a variety of polyvalent cations. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Sickle cell disease (SCD) is a genetic disorder characterized by the production of abnormal sickle-shaped red blood cells (called hemoglobin S, HbS) that initiate a pathophysiology resulting in severe pain, progressive multi-organ damage, and premature death. Treatment options for SCD are largely focused on preventing the production and circulation of...
Approved
Investigational
Matched Synonyms: … interspaced short palindromic repeats/CRISPR-associated protein 9) mediated gene editing consisting of a
Matched Description: … red blood cells (called hemoglobin S, HbS) that initiate a pathophysiology resulting in severe pain, ... [L10139] Following engraftment, it causes an increase in the production of HbF and a subsequent decrease ... [L49246] In January 2024, exagamglogene autotemcel received an additional FDA approval for the treatment …
Brilliant green, or ethanaminium, is a derivative of triarylmethane dye that has been used as a dye to color silk and wool. Due to its inhibitory actions against Gram positive microorganisms, brilliant green can be found in antiseptic products such as solutions and swabs used to prevent infection.
Approved
Vet approved
Matched Description: … Brilliant green, or ethanaminium, is a derivative of triarylmethane dye that has been used as a dye to ... Due to its inhibitory actions against Gram positive microorganisms, brilliant green can be found in antiseptic …
Matched Mixtures name: … Kerr 100 Triple Dye Dispos-A
Matched Categories: … Compounds used in a research, industrial, or household setting …
Alfacalcidol, or 1-alpha-hydroxycholecalciferol or 1-alpha-hydroxyvitamin D3, is a non-endogenous analogue of vitamin D. It plays an essential function in calcium homeostasis and bone metabolism. Alfacaldisol is activated by the enzyme 25-hydroxylase in the liver to mediate its effects in the body, or most importantly, the kidneys and bones. The pharmacological...
Approved
Nutraceutical
Matched Iupac: … (1R,3S,5Z)-5-{2-[(1R,3aS,4E,7aR)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-octahydro-1H-inden-4-ylidene] …
Matched Description: … [L33284] In approving European countries, alfacalcidol is also indicated for managing nutritional and ... Alfacalcidol, or 1-alpha-hydroxycholecalciferol or 1-alpha-hydroxyvitamin D3, is a non-endogenous analogue ... The pharmacological actions of alfacalcidol are prolonged than vitamin D because a negative feedback …
Matched Categories: … Drugs for Treatment of Bone Diseases …
Matched Products: … ONE-ALPHA DROPS 2 mcg/ml ... Etalpha 2 µg - Ampullen ... EINSALPHA 2 UG/ML TROPFEN …
Dexbrompheniramine maleate is an antihistamine agent that is used for the treatment of allergic conditions, such as hay fever or urticaria.
Approved
Matched Synonyms: … (R)-3-(4-Bromophenyl)-3-(2-pyridyl)propyldimethylamine ... 3-(4-bromophenyl)- N,N-dimethyl- 3-pyridin-2-yl-propan-1-amine …
Matched Iupac: … [(3S)-3-(4-bromophenyl)-3-(pyridin-2-yl)propyl]dimethylamine …
Matched Description: … Dexbrompheniramine maleate is an antihistamine agent that is used for the treatment of allergic conditions …
Matched Mixtures name: … Supress A ... Dexbrompheniramine-DM-Phenylephrine 2-15-7.5 …
Matched Categories: … Antihistamines for Systemic Use …
Hydroxyprogesterone caproate is a synthetic steroid hormone that is similar to medroxyprogesterone acetate and megestrol acetate. It is an ester derivative of 17α-hydroxyprogesterone formed from caproic acid (hexanoic acid). Hydroxyprogesterone caproate was previously marketed under the trade name Delalutin by Squibb, which was approved by the U.S. Food and Drug...
Approved
Investigational
Matched Iupac: … 11aS)-1-acetyl-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … of preterm delivery in women with a history of preterm delivery, sparking a pricing controversy. ... FDA approved Makena from KV Pharmaceutical (previously named as Gestiva) on February 4, 2011 for prevention ... Food and Drug Administration (FDA) in 1956 and withdrawn from marketing in 1999.[L46118] The U.S. …
Matched Mixtures name: … GRAVIDINONA 2 ML …
Matched Categories: … Hormonal Contraceptives for Systemic Use …
Matched Products: … LUGESRO 500 MG/2 ML ENJEKSİYONLUK ÇÖZELTİ, 1 ADET …
A nonfluorinated corticosteroid anti-inflammatory agent used topically for dermatoses.
Approved
Investigational
Matched Iupac: … (1S,2S,4R,8S,9S,11S,12S,13R)-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[ …
Matched Description: … A nonfluorinated corticosteroid anti-inflammatory agent used topically for dermatoses. …
Matched Mixtures name: … PRECORT-A KREM ... PRECORT-A POMAD ... PREDNOL-A 30 GR KREM …
Trypan blue is a diazo dye used in ophthalmic cataract surgery to stain the anterior capsule in the presence of a mature cataract. This is done to aid in visualization before creating the continuous curvilinear capsulorhexis.
Approved
Matched Iupac: … 5-amino-3-[(E)-2-{4'-[(E)-2-(8-amino-1-hydroxy-3,6-disulfonaphthalen-2-yl)diazen-1-yl]-3,3'-dimethyl- …
Matched Description: … Trypan blue is a diazo dye used in ophthalmic cataract surgery to stain the anterior capsule in the presence ... of a mature cataract. ... This is done to aid in visualization before creating the continuous curvilinear capsulorhexis. …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Sodium Acetate is chemically designated CH3COONa, a hygroscopic powder very soluble in water. Sodium acetate could be used as additives in food, industry, concrete manufacture, heating pads and in buffer solutions. Medically, sodium acetate is important component as an electrolyte replenisher when given intravenously. It is mainly indicated to correct...
Approved
Investigational
Matched Description: … It can be used also in metabolic acidosis and for urine alkalinization. ... It is mainly indicated to correct sodium levels in hyponatremic patients. ... Sodium Acetate is chemically designated CH3COONa, a hygroscopic powder very soluble in water. …
Matched Mixtures name: … Clinimix 3 % G-E - Infusionsbeutel ... Plasma-Lyte A ... PLASMA-LYTE A INJECTION …
Etonogestrel molecule is a 3-ketodesogestrel or 19-nortestosterone which is a synthetic biologically active metabolite of progestin desogestrel. The first product including etonogestrel was developed by the Merck subsidiary Organon and FDA approved in 2001.
Approved
Investigational
Matched Synonyms: … 3-Ketodesogestrel ... 3-Oxodesogestrel …
Matched Iupac: … -1-ethynyl-1-hydroxy-10-methylidene-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a] …
Matched Description: … Etonogestrel molecule is a 3-ketodesogestrel or 19-nortestosterone which is a synthetic biologically ... first product including etonogestrel was developed by the Merck subsidiary Organon and FDA approved in
Matched Categories: … Hormonal Contraceptives for Systemic Use …
Calendula officinalis flower is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Matched Description: … Calendula officinalis flower is a plant/plant extract used in some OTC (over-the-counter) products. …
Dermatophagoides farinae extracts are sterile solutions used for intradermal testing or subcutaneous immunotherapy. This combination is approved for as a year-round, once-a-day tablet that's dissolved under the tongue as a treatment for dust mite allergies.
Approved
Matched Description: … as a treatment for dust mite allergies. ... This combination is approved for as a year-round, once-a-day tablet that's dissolved under the tongue ... Dermatophagoides farinae extracts are sterile solutions used for intradermal testing or subcutaneous …
Iptacopan is a small-molecule factor B inhibitor previously investigated as a potential treatment for the rare blood disease paroxysmal nocturnal hemoglobinuria (PNH) by inhibiting the complement factor B. Factor B is a positive regulator of the alternative complement pathway, where it activates C3 convertase and subsequently C5 convertase. This is...
Approved
Investigational
Matched Synonyms: … 4-((2S,4S)-4-ethoxy-1-((5-methoxy-7-methyl-1H-indol-4-yl)methyl)piperidin-2-yl) benzoic acid ... BENZOIC ACID, 4-((2S,4S)-4-ETHOXY-1-((5-METHOXY-7-METHYL-1H-INDOL-4-YL)METHYL)-2-PIPERIDINYL)- …
Matched Iupac: … 4-[(2S,4S)-4-ethoxy-1-[(5-methoxy-7-methyl-1H-indol-4-yl)methyl]piperidin-2-yl]benzoic acid …
Matched Description: … Iptacopan is a small-molecule factor B inhibitor previously investigated as a potential treatment for ... that normally anchor 2 membrane proteins, CD55 and CD59, that protect blood cells against the alternative ... Due to this mutation, all progeny erythrocytes will lack the glycosyl phosphatidylinositol–anchored proteins …
Matched Salts cas: … 2447007-60-3
An anxiolytic benzodiazepine derivative with anticonvulsant, sedative, and amnesic properties. It has also been used in the symptomatic treatment of alcohol withdrawal.
Approved
Illicit
Investigational
Matched Synonyms: … 7-chloro-2-methylamino-5-phenyl-3H-1,4-benzodiazepin-4-oxide …
Matched Iupac: … 7-chloro-2-(methylamino)-5-phenyl-3H-1,4-benzodiazepin-4-ium-4-olate …
Matched Description: … It has also been used in the symptomatic treatment of alcohol withdrawal. …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Displaying drugs 301 - 325 of 15549 in total