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Displaying drugs 326 - 350 of 8113 in total

Sotalol

Sotalol is a methanesulfonanilide developed in 1960. It was the first of the class III anti arrhythmic drugs. Sotalol was first approved as an oral tablet on 30 October 1992. A racemic mixture of sotalol is currently formulated as a tablet, oral solution, and intravenous injection indicated for life threatening...
Approved
Matched Synonyms: … 4'-(1-hydroxy-2-(isopropylamino)ethyl)methane sulfonanilide …
Matched Iupac: … N-(4-{1-hydroxy-2-[(propan-2-yl)amino]ethyl}phenyl)methanesulfonamide …
Matched Products: … TALOZIN 40 MG/4 ML ENJEKSİYONLUK ÇÖZELTİ, 5 ADET …

Riluzole

A glutamate antagonist (receptors, glutamate) used as an anticonvulsant (anticonvulsants) and to prolong the survival of patients with amyotrophic lateral sclerosis. Riluzole is marketed as Rilutek by Sanofi.
Approved
Investigational
Matched Iupac: … 6-(trifluoromethoxy)-1,3-benzothiazol-2-amine …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … TEGLUTIK® SUSPENSIÓN ORAL 5 MG/ML ... Teglutik 5 mg/ml Suspension zum Einnehmen ... TEGLUTIK 5 MG/ ML ORAL SÜSPANSIYON, 300 ML …

Almotriptan

Almotriptan is a triptan drug for the treatment of migraine headaches. Almotriptan is in a class of medications called selective serotonin receptor agonists. It works by narrowing blood vessels in the brain, stopping pain signals from being sent to the brain, and stopping the release of certain natural substances that...
Approved
Investigational
Matched Synonyms: … 1-(((3-(2-(Dimethylamino)ethyl)indol-5-yl)methyl)sulfonyl)pyrrolidine …
Matched Iupac: … dimethyl(2-{5-[(pyrrolidine-1-sulfonyl)methyl]-1H-indol-3-yl}ethyl)amine …
Matched Salts cas: … 181183-52-8 …
Matched Categories: … Heterocyclic Compounds, 2-Ring ... Serotonin 5-HT1 Receptor Agonists ... Selective Serotonin 5-HT1 Receptor Agonists …

Beta carotene

Beta-carotene, with the molecular formula C40H56, belongs to the group of carotenoids consisting of isoprene units. The presence of long chains of conjugated double bonds donates beta-carotene with specific colors. It is the most abundant form of carotenoid and it is a precursor of the vitamin A. Beta-carotene is composed...
Approved
Nutraceutical
Matched Iupac: … 1,3,3-trimethyl-2-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-3,7,12,16-tetramethyl-18-(2,6,6-trimethylcyclohex …
Matched Mixtures name: … Vitaphil 90 DHA ... IV-8 Formula ... For-2 …

Nifedipine

Nifedipine, or BAY a 1040, is a first generation dihydropyridine L-type calcium channel blocker, similar to nicardipine.[A190210,A190273,A175390,L11383] Nifedipine was developed by Bayer and first described in the literature, along with other dihydropyridines, in 1972.[A175390,A190276] Since nifedipine's development, second and third generation dihydropyridines have been developed with slower onsets and longer...
Approved
Matched Synonyms: … 4-(2'-Nitrophenyl)-2,6-dimethyl-1,4-dihydropyridin-3,5-dicarbonsäuredimethylester …
Matched Iupac: … 3,5-dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate …
Matched Products: … CALCIANTA 5 ... เนลาปีน 5 ... อาดีปีน 5 …

Doripenem

Doripenem is a broad-spectrum, carbapenem antibiotic marketed under the brand name Doribax by Janssen. Doripenem injection was approved by the FDA in 2007 to treat complicated urinary tract and intra-abdominal infections. In a clinical trial of doripenem treatment in ventilator associated pneumonia (vs. imipenem and cilastatin), it was found that...
Approved
Investigational
Matched Iupac: … yl]sulfanyl}-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid ... (4R,5S,6S)-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-3-{[(3S,5S)-5-[(sulfamoylamino)methyl]pyrrolidin-3- …
Matched Salts cas: … 364622-82-2 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Antithymocyte immunoglobulin (rabbit)

Rabbit anti-thymocyte globulin. Thymoglobulin is a polyclonal antibody that suppresses certain types of immune cells responsible for acute organ rejection in transplant patients. Thymoglobulin is a mixture of antibodies intended to bind to various cell surface antigens. The most common mode of action of Thymoglobulin is via selective depletion of...
Approved
Matched Products: … Thymoglobuline 5 mg/ml - Pulver zur Herstellung einer Infusionslösung ... THYMOGLOBULİNE 5 MG-ML IV İNFÜZYON İÇİN LİYOFİLİZE TOZ İÇEREN FLAKON ... GRAFALON 5 ML IV INFUZYONLUK COZELTI KONSANTRESI ICEREN FLAKON, 1 ADET …

Misoprostol

Misoprostol is a prostaglandin analog used to reduce the risk of NSAID related ulcers, manage miscarriages, prevent post partum hemorrhage, and also for first trimester abortions.[L7616,L7619,A181589,A181583,A181697] The stimulation of prostaglandin receptors in the stomach reduces gastric acid secretion, while stimulating these receptors in the uterus and cervix can increase the...
Approved
Matched Iupac: … methyl 7-[(1R,2R,3R)-3-hydroxy-2-[(1E)-4-hydroxy-4-methyloct-1-en-1-yl]-5-oxocyclopentyl]heptanoate …
Matched Products: … MISODEL 200 MCG VAJINAL SALIM SISTEMI ,5 ADET …

Daprodustat

Daprodustat is a small-molecule hypoxia-inducible factor (HIF) prolyl hydroxylase (PHD) inhibitor that was developed by GSK.[A254167,A254162] Patients with CKD cannot induce erythropoietin (EPO) production in response to hypoxia or anemia. As a potent inhibitor of PHD1, PHD2 and PHD3 (≥ 1000-fold selectivity), daprodustat stabilizes cellular HIF1α and HIF2α and the induces...
Approved
Investigational
Matched Synonyms: … Glycine, N-((1,3-dicyclohexylhexahydro-2,4,6-trioxo-5-pyrimidinyl)carbonyl)- …
Matched Iupac: … 2-[(1,3-dicyclohexyl-2,4,6-trioxo-1,3-diazinan-5-yl)formamido]acetic acid …

Mitapivat

Mitapivat is a novel, first-in-class pyruvate kinase activator. It works to increase the activity of erythrocyte pyruvate kinase, a key enzyme involved in the survival of red blood cells. Defects in the pyruvate kinase enzyme in various red blood cells disorders lead to the lack of energy production for red...
Approved
Investigational
Matched Iupac: … N-{4-[4-(cyclopropylmethyl)piperazine-1-carbonyl]phenyl}quinoline-8-sulfonamide …
Matched Categories: … Heterocyclic Compounds, 2-Ring …

Benzylpenicillin

Benzylpenicillin (Penicillin G) is narrow spectrum antibiotic used to treat infections caused by susceptible bacteria. It is a natural penicillin antibiotic that is administered intravenously or intramuscularly due to poor oral absorption. Penicillin G may also be used in some cases as prophylaxis against susceptible organisms. Natural penicillins are considered...
Approved
Vet approved
Matched Synonyms: … 6-(2-phenylacetamido)penicillanic acid ... (2S,5R,6R)-3,3-dimethyl-7-oxo-6-(phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Iupac: … (2S,5R,6R)-3,3-dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid …
Matched Salts cas: … 751-84-8 ... 69-57-8 ... 973-53-5 ... 41372-02-5 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … Penicillin G-Natrium Sandoz 5 Mega IE - Trockenstechampulle …

Clozapine

Clozapine is a tricyclic dibenzodiazepine, classified as an atypical antipsychotic agent. Clozapine displays affinity to various neuroreceptors with a particularly low affinity to the dopamine receptors, thus breaking the mold of first-generation antipsychotics and deeming it "atypical". . This low affinity to dopamine receptors results in fewer extrapyramidal side effects,...
Approved
Matched Categories: … Serotonin 5-HT1 Receptor Antagonists ... Serotonin 5-HT2 Receptor Antagonists ... Serotonin 5-HT1A Receptor Antagonists ... Serotonin 5-HT1D Receptor Antagonists ... Serotonin 5-HT2A Receptor Antagonists …

Technetium Tc-99m sestamibi

Technetium Tc-99m sestamibi (commonly sestamibi) is a pharmaceutical agent used in nuclear medicine imaging. The drug is a coordination complex consisting of the radioisotope technetium-99m bound to six methoxyisobutylisonitrile (MIBI) ligands, hence the name sesta (6) MIBI.. Following intravenous injection of the drug, Technetium Tc-99m sestamibi is taken up by...
Approved
Investigational
Matched Iupac: … technetium(1+) ion hexakis(1-isocyano-2-methoxy-2-methylpropane) …
Matched Description: … by localizing myocardial ischemia (reversible defects) and infarction (non-reversible defects); and 2) …

Sucrose

A nonreducing disaccharide composed of glucose and fructose linked via their anomeric carbons. It is obtained commercially from sugarcane, sugar beet (beta vulgaris), and other plants and used extensively as a food and a sweetener.
Approved
Experimental
Investigational
Matched Synonyms: … 1-alpha-D-Glucopyranosyl-2-beta-D-fructofuranoside …
Matched Iupac: … (2R,3R,4S,5S,6R)-2-{[(2S,3S,4S,5R)-3,4-dihydroxy-2,5-bis(hydroxymethyl)oxolan-2-yl]oxy}-6-(hydroxymethyl …

Tacrolimus

Tacrolimus (also FK-506 or Fujimycin) is an immunosuppressive drug whose main use is after organ transplant to reduce the activity of the patient's immune system and so the risk of organ rejection. It is also used in a topical preparation in the treatment of severe atopic dermatitis, severe refractory uveitis...
Approved
Investigational
Matched Iupac: … ,21S,23S,24R,25S,27R)-1,14-dihydroxy-12-[(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2- ... yl]-23,25-dimethoxy-13,19,21,27-tetramethyl-17-(prop-2-en-1-yl)-11,28-dioxa-4-azatricyclo[22.3.1.0^{4,9 …
Matched Description: … This FKBP12-FK506 complex inhibits calcineurin which inhibits T-lymphocyte signal transduction and IL-2 …
Matched Products: … Adport 2 mg - Hartkapseln ... Dailiport 2 mg - Hartkapseln, retardiert ... DAİLİPORT 2 MG UZATILMIŞ SALIMLI SERT KAPSÜL , 30 ADET …

Zinc

A metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with anemia, short stature, hypogonadism, impaired wound...
Approved
Investigational
Matched Description: … polymorphism of the common polymorphism in zinc transporter _SLC30A8/ZnT8_ may increase susceptibility to type 2 …
Matched Mixtures name: … IV-8 Formula ... MENAPHASE FORMULA FILM TABLET, 90 ADET ... QBx (formerly known as PHI-5, K041059) …
Matched Products: … ZINCO-K 15MG/5 ML 28 KASIK SURUP ... ZINCLOMIN 15 MG/5 ML 100 ML SURUP ... ZINCO-K 15MG/5 ML KASIK SURUP, 20 ADET …

Lesinurad

Lesinurad is an oral uric acid transporter 1 (URAT1) inhibitor indicated for the treatment of hyperuricemia associated with gout. It reduces serum uric acid concentration through the inhibition of URAT1, an enzyme responsible for reuptake of uric acid from the renal tubule, and OAT4, another uric acid transporter associated with...
Approved
Investigational
Matched Synonyms: … {[5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetic acid …
Matched Iupac: … 2-{[5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetic acid …

Milrinone

Heart failure is a multifactorial condition that affects roughly 1-2% of the adult population. Often the result of long-term myocardial ischemia, cardiomyopathy, or other cardiac insults, heart failure results from an inability of the heart to perfuse peripheral tissues with sufficient oxygen and metabolites, resulting in complex systemic pathologies. Heart...
Approved
Matched Synonyms: … 1,6-Dihydro-2-methyl-6-oxo(3,4'-bipyridine)-5-carbonitrile …
Matched Iupac: … 2-methyl-6-oxo-1,6-dihydro-[3,4'-bipyridine]-5-carbonitrile …
Matched Description: … Heart failure is a multifactorial condition that affects roughly 1-2% of the adult population. …

Lomefloxacin

Lomefloxacin is a fluoroquinolone antibiotic, used to treat bacterial infections including bronchitis and urinary tract infections (UTIs). Additionally, it has been employed for the prophylaxis of UTIs prior to surgery as well.
Approved
Investigational
Matched Salts cas: … 98079-52-8 …
Matched Categories: … Heterocyclic Compounds, 2-Ring …
Matched Products: … OKACIN GOZ DAMLASI 3 MG/ML 5 ML …

Demeclocycline

A tetracycline analog having a 7-chloro and a 6-methyl. Because it is excreted more slowly than tetracycline, it maintains effective blood levels for longer periods of time.
Approved
Matched Synonyms: … 12aα)]-7-chloro-4-(dimethylamino)1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-1,11-dioxo-2- …
Matched Iupac: … chloro-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2- …
Matched Salts cas: … 17146-81-5 …

Iodine

Iodine is commonly used as an antiseptic for minor cuts and abrasions, preventing infections that may result from contaminated wounds. Additionally, iodine has been studied in the treatment of fibrocystic disease and breast cancer.[A3413,A192153,A192156,A192159]
Approved
Investigational
Matched Mixtures name: … Focalgin 90 DHA ... Iodine Tct 5% CF ... Tincture Of Iodine 5% …
Matched Products: … Tincture Of Iodine 5% …

Antazoline

Antazoline is a 1st generation antihistamine with anticholinergic activity. It is used to relieve nasal congestion. It is also formulated as eye drops with naphazoline to relieve allergic conjunctivitis.
Approved
Matched Synonyms: … 2-(N-Benzylanilinomethyl)-2-imidazoline ... 2-(N-Phenyl-N-benzylaminomethyl)imidazoline ... 4,5-Dihydro-N-phenyl-N-phenylmethyl-1H-imidazole-2-methanamine …
Matched Iupac: … N-benzyl-N-[(4,5-dihydro-1H-imidazol-2-yl)methyl]aniline …

Enalaprilat

Enalaprilat is the active metabolite of the orally available pro-drug, enalapril. Used in the treatment of hypertension, enalapril is an ACE inhibitor that prevents Angiotensin Converting Enzyme (ACE) from transforming angiotensin I into angiotensin II. As angiotensin II is responsible for vasoconstriction and sodium reabsorption in the proximal tubule of...
Approved
Matched Iupac: … (2S)-1-[(2S)-2-{[(1S)-1-carboxy-3-phenylpropyl]amino}propanoyl]pyrrolidine-2-carboxylic acid …

Influenza A virus A/Texas/50/2012 X-223A (H3N2) antigen (UV, formaldehyde inactivated)

A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved

Iothalamic acid

Iothalamic acid is an iodine containing organic anion used as a diagnostic contrast agent.
Approved
Matched Synonyms: … 1-deoxy-1-(methylamino)-D-glucitol 5-acetamido-2,4,6 triiodo-N-methylisophthalamate …
Matched Iupac: … 3-acetamido-2,4,6-triiodo-5-(methylcarbamoyl)benzoic acid …
Displaying drugs 326 - 350 of 8113 in total