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Displaying drugs 376 - 400 of 14373 in total

Unoprostone

Unoprostone isopropyl is a prostaglandin analogue. Ophthalmic Solution 0.15% is a synthetic docosanoid. Unoprostone isopropyl has the chemical name isopropyl (+)-(Z)-7-[(1R,2R,3R,5S)-3,5 dihydroxy-2-(3-oxodecyl)cyclopentyl]-5-heptenoate. The main indication of Unoprostane is treatment of glucoma.
Approved
Investigational
Matched Categories: … Antiglaucoma Preparations and Miotics …

Gadoteric acid

Gadoteric acid, commonly used in the salt form gadoterate meglumine, is a macrocyclic, ionic gadolinium-based contrast agent (GBCA). It is composed of the organic acid DOTA (1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid) used for its chelating properties, and gadolinium (Gd3+). Gadoterate meglumine has one of the highest thermodynamic stability, apparent stability, and kinetic stability,...
Approved
Matched Description: … associated tissues in adult and pediatric patients (2 years of age and older) to detect and visualize ... areas with disruption of the blood-brain barrier (BBB) and/or abnormal vascularity. ... DOTA (1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid) used for its chelating properties, and …

Iomeprol

Iomeprol has been investigated for the diagnostic of Coronary Artery Disease.
Approved
Investigational

Mandelic acid

Mandelic acid is an approved aromatic, alpha hydroxy acid . Mandelic acid is used as an ingredient in cosmetics and drug products applied topically.
Approved
Matched Description: … Mandelic acid is used as an ingredient in cosmetics and drug products applied topically. …
Matched Categories: … Blood and Blood Forming Organs ... Blood Substitutes and Perfusion Solutions …

Sodium feredetate

Approved
Matched Categories: … Blood and Blood Forming Organs …

Pentetic acid

Pentetic acid, also known as diethylenetriaminepentaacetic acid (DTPA), is a synthetic polyamino carboxylic acid with eight coordinate bond forming sites that can sequester metal ions and form highly stable DTPA-metal ion complexes. DTPA, along with its calcium and zinc trisodium salts, are the only FDA approved agents for the treatment...
Approved
Matched Description: … [L2242] DPTA was developed by the pharmaceutical company CIS US and FDA approved on April 14, 2004. ... DTPA, along with its calcium and zinc trisodium salts, are the only FDA approved agents for the treatment ... synthetic polyamino carboxylic acid with eight coordinate bond forming sites that can sequester metal ions and …

Chromium gluconate

Approved

Edetate disodium anhydrous

Edetate disodium anhydrous is a polyvalent chelating agent used to treat hypercalcemia and digitalis toxicity associated ventricular arrhythmias.
Approved
Vet approved
Matched Description: … Edetate disodium anhydrous is a polyvalent chelating agent used to treat hypercalcemia and digitalis …

Cabergoline

Cabergoline, an ergot derivative, is a long-acting dopamine agonist and prolactin inhibitor. It is used to treat hyperprolactinemic disorders and Parkinsonian Syndrome. Cabergoline possesses potent agonist activity on dopamine D2 receptors.
Approved
Matched Description: … It is used to treat hyperprolactinemic disorders and Parkinsonian Syndrome. ... Cabergoline, an ergot derivative, is a long-acting dopamine agonist and prolactin inhibitor. …
Matched Categories: … Ergot Alkaloids and Derivatives ... Genito Urinary System and Sex Hormones …

Travoprost

Travoprost is a synthetic isopropyl ester prodrug of a prostaglandin F2alpha (F2α) analogue and selective FP prostanoid receptor agonist. It is used to decrease intraocular pressure in open-angle glaucoma and ocular hypertension. Unlike other prostaglandin analogues, travoprost demonstrates full agonism and high selectivity at the prostanoid receptor, reporting a higher...
Approved
Matched Description: … It is used to decrease intraocular pressure in open-angle glaucoma and ocular hypertension. ... Travoprost is a synthetic isopropyl ester prodrug of a prostaglandin F2alpha (F2α) analogue and selective ... [L49434] Unlike other prostaglandin analogues, travoprost demonstrates full agonism and high selectivity …
Matched Categories: … Antiglaucoma Preparations and Miotics …

Leucovorin

Folinic Acid (also known as 5-formyl tetrahydrofolic acid or leucovorin) is the 5-formyl derivative of tetrahydrofolic acid, a necessary co-factor in the body. Commercially available leucovorin is composed of a 1:1 racemic mixture of the dextrorotary and levorotary isomers, while levoleucovorin contains only the pharmacologically active levo-isomer. In vitro, the...
Approved
Matched Description: … Commercially available leucovorin is composed of a 1:1 racemic mixture of the dextrorotary and levorotary ... activity, the two commercially available forms have been shown to be pharmacokinetically identical and ... As folate analogs, leucovorin and levoleucovorin are both used to counteract the toxic effects of folic …
Matched Categories: … Enzymes and Coenzymes ... Folic Acid and Derivatives …

Cyclopentolate

A parasympatholytic anticholinergic used solely to obtain mydriasis or cycloplegia.
Approved
Matched Categories: … Mydriatics and Cycloplegics …

Auranofin

Auranofin is a gold salt that is capable of eliciting pharmacologic actions that suppress inflammation and stimulate cell-mediated immunity. It has subsequently been listed by the World Health Organization as a member of the antirheumatic agent category. Auranofin appears to induce heme oxygenase 1 (HO-1) mRNA. Heme oxygenase 1 is...
Approved
Investigational
Matched Description: … Auranofin is a gold salt that is capable of eliciting pharmacologic actions that suppress inflammation and …
Matched Categories: … Antiinflammatory and Antirheumatic Products …

Hydroxyurea

Hydroxyurea is a non-alkylating antineoplastic agent that was first synthesized in 1869 but was not characterized biologically until 1928. It was first approved by the FDA in 1998 for the treatment of sickle cell anemia in adults. Although clinical evidence on the efficacy of hydroxyurea in certain conditions exists, hydroxyurea...
Approved
Matched Description: … adherence, the need for therapeutic monitoring, and serious side effects of secondary cancer and birth ... conditions exists, hydroxyurea is used sparingly in clinical settings, largely due to lack of knowledge and …
Matched Categories: … Antineoplastic and Immunomodulating Agents …

Dinoprost tromethamine

The tromethamine (THAM) salt of the naturally occurring prostaglandin F2 alpha, dinoprost tromethamine occurs as a white to off-white, very hygroscopic, crystalline powder. Dinoprost tromethamine may also be known as dinoprost trometamol, PGF2 alpha THAM, or prostaglandin F2 alpha tromethamine.
Approved
Vet approved

Iodipamide

Iodipamide is a water-soluble radiographic contrast media for cholecystography and intravenous cholangiography.
Approved
Matched Description: … Iodipamide is a water-soluble radiographic contrast media for cholecystography and intravenous cholangiography …

Tafluprost

A prostaglandin analogue ester prodrug used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. Chemically, tafluprost is a fluorinated analog of prostaglandin F2-alpha. Tafluprost was approved for use in the U.S. on February 10, 2012.
Approved
Matched Description: … prostaglandin analogue ester prodrug used topically (as eye drops) to control the progression of glaucoma and …
Matched Categories: … Antiglaucoma Preparations and Miotics …

Inositol nicotinate

Inositol nicotinate, also known as Inositol hexaniacinate/hexanicotinate or "no-flush niacin", is a niacin ester and vasodilator. It is used in food supplements as a source of niacin (vitamin B3), where hydrolysis of 1 g (1.23 mmol) inositol hexanicotinate yields 0.91 g nicotinic acid and 0.22 g inositol. Niacin exists in...
Approved
Withdrawn
Matched Description: … nicotinate, also known as Inositol hexaniacinate/hexanicotinate or "no-flush niacin", is a niacin ester and ... Niacin exists in different forms including nicotinic acid, nicotinamide and other derivatives such as ... vitamin B3), where hydrolysis of 1 g (1.23 mmol) inositol hexanicotinate yields 0.91 g nicotinic acid and …
Matched Categories: … Nicotinic Acid and Derivatives …

Ioversol

Ioversol is a non-ionic compound with a tri-iodinated benzene ring used as a contrast dye in diagnostic procedures to visualize different types of organs and tissues. Iodine has a high atomic density, which gives it the ability to attenuate X-rays. The intravascular administration of iodine compounds, such as ioversol, enhances...
Approved
Matched Description: … (CT) imaging and contrast enhancement in peripheral arteriography, coronary arteriography, and left ... benzene ring used as a contrast dye in diagnostic procedures to visualize different types of organs and ... the inadvertent intrathecal administration of ioversol, which is only indicated for intra-arterial and …

Dinoprost

Dinoprost has been investigated in Headache.
Approved
Investigational
Matched Categories: … Genito Urinary System and Sex Hormones …

Reserpine

An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool,...
Approved
Investigational
Withdrawn
Matched Description: … serotonin from central and peripheral axon terminals. ... An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. ... inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and …
Matched Categories: … reserpine and diuretics ... reserpine and diuretics, combinations with other drugs ... reserpine and diuretics, combinations with psycholeptics …

Anisotropine methylbromide

Anisotropine methylbromide is a quaternary ammonium compound. Its use as treatment adjunct in peptic ulcer has been replaced by the use of more effective agents. Depending on the dose, anisotropine methylbromide may reduce the motility and secretory activity of the gastrointestinal system, and the tone of the ureter and urinary...
Approved
Matched Description: … gastrointestinal system, and the tone of the ureter and urinary bladder and may have a slight relaxant ... , and accommodation; cause dilatation of the pupil; and increase the heart rate. ... Larger doses are required to decrease motility of the gastrointestinal and urinary tracts and to inhibit …

Toremifene

Toremifene is a selective estrogen receptor modulator (SERM) and a nonsteroidal antiestrogen used to treat estrogen receptor positive breast cancer. Like tamoxifen, toremifene is part of the first-generation triphenylethylene derivative chemical class of SERMs. Toremifene possesses tissue-specific actions: it has estrogenic (agonist) activity on the cardiovascular system and on bone...
Approved
Investigational
Matched Description: … Toremifene is a selective estrogen receptor modulator (SERM) and a nonsteroidal antiestrogen used to ... possesses tissue-specific actions: it has estrogenic (agonist) activity on the cardiovascular system and ... on bone tissue and it has weak estrogenic effects on uterine tissue, however, it also has antiestrogenic …
Matched Categories: … Antineoplastic and Immunomodulating Agents ... Hormone Antagonists and Related Agents ... Hormones, Hormone Substitutes, and Hormone Antagonists …

Apomorphine

Apomorphine is a non-ergoline dopamine D2 agonist indicated to treat hypomobility associated with Parkinson's. It was first synthesized in 1845 and first used in Parkinson's disease in 1884. Apomorphine has also been investigated as an emetic, a sedative, a treatment for alcoholism, and a treatment of other movement disorders.[A203597,A203618] Apomorphine...
Approved
Investigational
Matched Description: … It was first synthesized in 1845 and first used in Parkinson's disease in 1884. ... A203618] Apomorphine has also been investigated as an emetic, a sedative, a treatment for alcoholism, and …
Matched Categories: … Genito Urinary System and Sex Hormones …

Metyrosine

An inhibitor of the enzyme tyrosine 3-monooxygenase, and consequently of the synthesis of catecholamines. It is used to control the symptoms of excessive sympathetic stimulation in patients with pheochromocytoma. (Martindale, The Extra Pharmacopoeia, 30th ed)
Approved
Matched Description: … An inhibitor of the enzyme tyrosine 3-monooxygenase, and consequently of the synthesis of catecholamines …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Displaying drugs 376 - 400 of 14373 in total