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Displaying drugs 26 - 50 of 10666 in total

Ebola Zaire vaccine (live, attenuated)

Ebola virus vaccine is a vaccine used to prevent Ebola virus disease caused by Zaire ebolavirus in adults, prevent outbreaks, and reduce the extent of the virus spreading in case of outbreaks. Ebola virus disease, formerly known as Ebola hemorrhagic fever, is a rare but severe and often deadly disease....
Approved
Matched Synonyms: … Recombinant Vesicular Stomatitis Virus (rVSV) strain Indiana with a deletion of the VSV envelope glycoprotein …
Matched Description: … adults, prevent outbreaks, and reduce the extent of the virus spreading in case of outbreaks. ... Ervebo consists of an envelope glycoprotein of the Zaire ebolavirus (Kikwit 1995 strain) fused into a ... The mortality rate of the Zaire species is about 80%. …

Ailanthus altissima pollen

Ailanthus altissima pollen is the pollen of the Ailanthus altissima plant. Ailanthus altissima pollen is mainly used in allergenic testing.
Approved
Matched Description: … Ailanthus altissima pollen is mainly used in allergenic testing. ... Ailanthus altissima pollen is the pollen of the Ailanthus altissima plant. …
Matched Products: … Tree of Heaven ... Tree Of Heaven Pollen ... Tree of Heaven Pollen …

Technetium Tc-99m disofenin

Technetium Tc-99m disofenin is a radiopharmaceutical agent used in hepatobiliary imaging for diagnostic purposes. It is well suited for both planar and single photon tomographic scintigraphy to quantitatively measure the function of liver, gallbladder and bile ducts and detect any anatomical changes in the hepatobliary system. It is available as...
Approved
Matched Description: … suited for both planar and single photon tomographic scintigraphy to quantitatively measure the function of ... It is available as an intravenous injection in a preparation kit under the name Hepatolite. ... Technetium Tc-99m disofenin is a radiopharmaceutical agent used in hepatobiliary imaging for diagnostic …
Matched Categories: … Diagnostic Uses of Chemicals ... Compounds used in a research, industrial, or household setting …
Matched Products: … Kit for the Preparation of Technetium Tc99m Disofenin …

Milk thistle

Milk thistle is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Approved
Experimental
Investigational
Matched Synonyms: … Fruit of Silybum Marianum …
Matched Description: … Milk thistle is a plant/plant extract used in some OTC (over-the-counter) products. …

Technetium Tc-99m sestamibi

Technetium Tc-99m sestamibi (commonly sestamibi) is a pharmaceutical agent used in nuclear medicine imaging. The drug is a coordination complex consisting of the radioisotope technetium-99m bound to six methoxyisobutylisonitrile (MIBI) ligands, hence the name sesta (6) MIBI.. Following intravenous injection of the drug, Technetium Tc-99m sestamibi is taken up by...
Approved
Investigational
Matched Description: … Technetium Tc-99m sestamibi (commonly sestamibi) is a pharmaceutical agent used in nuclear medicine imaging ... (non-reversible defects); and 2) evaluating myocardial function and developing information for use in ... Following intravenous injection of the drug, Technetium Tc-99m sestamibi is taken up by the myocardium …
Matched Categories: … Diagnostic Uses of Chemicals ... Compounds used in a research, industrial, or household setting …
Matched Products: … Kit for the Preparation of Technetium Tc99m Sestamibi …

Betiatide

Approved
Experimental
Matched Products: … Kit for the Preparation of Technetium Tc99m Mertiatide …

Morphine

Morphine, the main alkaloid of opium, was first obtained from poppy seeds in 1805. It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse. Morphine is still routinely used today, though there are a number of semi-synthetic opioids of varying strength...
Approved
Investigational
Matched Synonyms: … (5R,6S,9R,13S,14R)-4,5-epoxy-N-methyl-7-morphinen-3,6-diol …
Matched Iupac: … (1S,5R,13R,14S,17R)-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca-7(18),8,10,15 …
Matched Description: … Morphine, the main alkaloid of opium, was first obtained from poppy seeds in 1805. ... Morphine was granted FDA approval in 1941.[L12114] ... [A176050] Morphine is still routinely used today, though there are a number of semi-synthetic opioids …
Matched Salts cas: … 596-16-7 ... 6055-06-7 …
Matched Categories: … Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome …
Matched Products: … Oramorph 10 mg - orale Lösung in Einzeldosisbehältern ... Oramorph 30 mg - orale Lösung in Einzeldosisbehältern ... Oramorph 100 mg - orale Lösung in Einzeldosisbehältern …

Erenumab

Erenumab (AMG-334) (INN; trade name Aimovig) is a human monoclonal antibody designed specifically to bind and antagonize the calcitonin gene-related peptide receptor (CGRPR) as a means to prevent migraines. Aimovig, as released and marketed by Novartis and Amgen, is in fact a novel therapeutic approach as the first and only...
Approved
Investigational
Matched Description: … Aimovig) is a human monoclonal antibody designed specifically to bind and antagonize the calcitonin gene-related ... It is composed of 2 heavy chains, each containing 456 amino acids, and 2 light chains of the lambda subclass ... , each containing 216 amino acids, with an approximate molecular weight of 150 kDa [FDA Label]. …
Matched Categories: … Calcitonin Gene-Related Peptide (CGRP) Antagonists ... Calcitonin Gene-Related Peptide Receptor Antagonists …
Matched Products: … AIMOVIG SOLUTION FOR INJECTION IN PRE-FILLED PEN 70MG/ML ... AIMOVIG SOLUTION FOR INJECTION IN PRE-FILLED PEN 140MG/ML ... AIMOVIG SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 70MG/ML …

Galcanezumab

Galcanezumab is a humanized monoclonal antibody developed by Eli Lilly and Company against human calcitonin gene-related peptide (CGRP). Although several small-molecule CGRP receptor antagonists have been developed, humanized monoclonal antibodies like galcanezumab are specifically designed to selectively bind to CGRP entities with high potency. Given this target specificity, lack of...
Approved
Investigational
Matched Description: … A pregnancy exposure registry has been established to evaluate the safety of this drug in pregnant women ... Galcanezumab is a humanized monoclonal antibody developed by Eli Lilly and Company against human calcitonin gene-related ... treatment of migraine and the treatment of episodic cluster headache. …
Matched Categories: … Calcitonin Gene-Related Peptide (CGRP) Antagonists ... Calcitonin Gene-Related Peptide Receptor Antagonists …
Matched Products: … EMGALITY SOLUTION FOR INJECTION IN PRE-FILLED PEN 120 MG/ML ... Pontevia 120 mg solution for injection in pre-filled pen ... Pontevia 120 mg solution for injection in pre-filled syringe …

Gadobutrol

Gadobutrol is a second-generation extracellular non-ionic macrocyclic GBCA (gadolinium-based contrast agent) used in magnetic resonance imaging (MRI) in adults and children older than 2 years of age. Due to its physicochemical properties, gadobutrol is formulated at twice the gadolinium ion concentration compared to other GBCA and thus requires a lesser...
Approved
Matched Iupac: … [5.5.1.0^{4,13}.0^{10,13}]tridecane-1,4,7,10-tetraium-13-uide ... 4,7,10-tris(carboxymethyl)-1-[(2S,3R)-1,3,4-trihydroxybutan-2-yl]-1,4,7,10-tetraaza-13-gadolinatetracyclo …
Matched Description: … magnetic resonance imaging (MRI) in adults and children older than 2 years of age. ... a second-generation extracellular non-ionic macrocyclic GBCA (gadolinium-based contrast agent) used in ... of NSF thanks to the macrocyclic structures that limit dechelation of gadolinium. …
Matched Categories: … Diagnostic Uses of Chemicals ... Compounds used in a research, industrial, or household setting …
Matched Products: … Gadograf 1,0 mmol/ml Injektionslösung in Fertigspritzen ... Gadovist 1,0 mmol/ml Injektionslösung in Fertigspritzen/Patronen …

Valerian

Valerian is extracted from a herb that is a perennial flowering plant. Valerian root is reported to have sedative and anxiolytic effects however its mechanism of action is not completely understood. Valerian has been used in the treatment of conditions including sleep disorders, anxiety, attention deficit-hyperactivity disorder (ADHD) and joint...
Approved
Experimental
Investigational
Matched Description: … Valerian has been used in the treatment of conditions including sleep disorders, anxiety, attention deficit-hyperactivity ... [DB00313] is a derivative of valeric acid, which is obtained from the plant root. ... Valerian root is reported to have sedative and anxiolytic effects however its mechanism of action is …
Matched Mixtures name: … Lapidar 7 Tab …
Matched Products: … Tincture Of Valerian …

Streptococcus pneumoniae type 23f capsular polysaccharide antigen

Streptococcus pneumoniae type 23f capsular polysaccharide antigen is a vaccine that contains highly purified capsular polysaccharides from the invasive pneumococcal type 23f of Streptococcus pneumoniae. It is an active immunization for intramuscular or subcutaneous injection against pneumococcal disease such as pneumococcal pneumonia and pneumococcal bacteremia.
Approved
Investigational
Matched Description: … vaccine that contains highly purified capsular polysaccharides from the invasive pneumococcal type 23f of …
Matched Mixtures name: … PNEUMOVAX 23 Injektionslösung in einer Fertigspritze ... PNEUMOVAX 23 Injektionslösung in einer Durchstechflasche ... Prevnar 13 …

Corynebacterium diphtheriae

Corynebacterium diphtheriae toxin is extracted from the pathogenic actinobacterium C. diphtheriae that causes diphtheria. The bacteria culture is grown in a medium and through purification, diphtheria toxin is detoxified with formaldehyde and diafiltered. The vaccine is intramuscularly administered to provide active immunization against diphtheria in infants and children.
Approved
Investigational
Matched Description: … The bacteria culture is grown in a medium and through purification, diphtheria toxin is detoxified with ... The vaccine is intramuscularly administered to provide active immunization against diphtheria in infants …
Matched Mixtures name: … Prevnar 13 ... PREVENAR 13 SUSPENSION FOR INJECTION ... Boostrix Injektionssuspension in einer Fertigspritze …

Aflibercept

Aflibercept is a recombinant protein composed of the binding domains of two human vascular endothelial growth factor (VEGF) receptors, VEGFR1 and VEGFR2, fused with the Fc region of human immunoglobulin gamma 1 (IgG1). Structurally, Aflibercept is a dimeric glycoprotein with a protein molecular weight of 96.9 kilo Daltons (kDa). It...
Approved
Matched Description: … retinopathy of prematurity in preterm infants in February 2023 and for the treatment of wet age-related ... [L47976] An aflibercept biosimilar, Yesafili, was approved for use in the EU in September 2023. ... Aflibercept is a recombinant protein composed of the binding domains of two human vascular endothelial …
Matched Products: … EYLEA 40MG/ML SOLUTION FOR INJECTION IN VIAL ... EYLEA SOLUTION FOR INJECTION IN VIAL 2MG ... EYLEA SOLUTION FOR INJECTION IN PREFILLED SYRINGE 2MG …

Etanercept

Dimeric fusion protein consisting of the extracellular ligand-binding portion of the human 75 kilodalton (p75) tumor necrosis factor receptor (TNFR) linked to the Fc portion of human IgG1.[L14862,A216522] The Fc component of etanercept contains the CH2 domain, the CH3 domain and hinge region, but not the CH1 domain of IgG1....
Approved
Investigational
Matched Description: … Etanercept is produced by recombinant DNA technology in a Chinese hamster ovary (CHO) mammalian cell ... Dimeric fusion protein consisting of the extracellular ligand-binding portion of the human 75 kilodalton ... It consists of 934 amino acids. …
Matched Products: … BENEPALI 50MG IN FER ... BENEPALI 25MG ILO IN FER ... ERELZI 25MG ILO IN FER …

Mobocertinib

Mobocertinib is a kinase inhibitor targeted against human epidermal growth factor receptor (EGFR). It is used specifically in the treatment of non-small cell lung cancer (NSCLC) caused by exon 20 insertion mutations in the EGFR gene, which are typically associated with a poorer prognosis (as compared to "classical" EGFR mutants...
Approved
Investigational
Matched Description: … It is used specifically in the treatment of non-small cell lung cancer (NSCLC) caused by exon 20 insertion ... September 2021 for the treatment of locally advanced or metastatic NSCLC in patients with _EGFR_ exon ... mutations in the _EGFR_ gene,[L38368] which are typically associated with a poorer prognosis (as compared …

Insulin glulisine

Insulin glulisine is a short-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes. Insulin is typically prescribed for the management of diabetes mellitus to mimic the activity of endogenously produced human insulin, a peptide hormone produced by beta cells of the...
Approved
Matched Description: … high levels of insulin in a short period of time to mimic the release of endogenous insulin from the ... Insulin is also used in the treatment of Type 2 Diabetes (T2D), another form of diabetes mellitus that ... reaction that destroys the beta cells of the pancreas, resulting in the body not being able to produce …
Matched Categories: … Drugs Used in Diabetes …
Matched Products: … APIDRA 100 U/ML- SOLUTION FOR INJECTION IN VIAL ... APIDRA 100 Units/ml Solution for Injection in vial ... APIDRA SOLOSTAR 100 UNITS/ML, SOLUTION FOR INJECTION IN A PRE-FILLED PEN …

Elranatamab

Elranatamab is a bispecific B-cell maturation antigen (BCMA)-directed CD3 T-cell engager. It is a humanized immunoglobulin 2-alanine kappa antibody derived from two monoclonal antibodies (mAbs), an anti-BCMA mAb and an anti-CD3 mAb, each of which contributes one heavy chain and one light chain to drug structure. The resulting 4-chain bispecific...
Approved
Investigational
Matched Synonyms: … B-CELL MATURATION ANTIGEN (BCMA) CLUSTER OF DIFFERENTIATION 3 (CD3) BISPECIFIC MONOCLONAL ANTIBODY (MAB …
Matched Description: … derived from two monoclonal antibodies (mAbs), an anti-BCMA mAb and an anti-CD3 mAb,[A261060] each of ... [L47815] On August 14, 2023, the FDA granted accelerated approval to elranatamab for the treatment of …

Evolocumab

Evolocumab is a monoclonal antibody designed for the treatment of hyperlipidemia by Amgen. It is a subcutaneous injection approved by the FDA for individuals on maximum statin therapy who still require additional LDL-cholesterol lowering. It is approved for both homozygous and heterozygous familial cholesterolemia as an adjunct to other first-line...
Approved
Matched Description: … designed to bind to PCSK9 and inhibit PCSK9 from binding to LDL receptors on the liver surface, resulting in ... Evolocumab is a monoclonal antibody designed for the treatment of hyperlipidemia by Amgen. ... more LDL receptors on the surface of the liver to remove LDL-C from the blood. …
Matched Products: … REPATHA SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 140MG/ML ... Repatha Solution for Injection in Pre-filled Syringe 140mg/mL (evolocumab) ... REPATHA SOLUTION FOR INJECTION IN PRE-FILLED AUTOINJECTOR 140MG/ML …

Rotavirus vaccine

Rotavirus commonly infects children and infants causing severe diarrhea and vomiting leading to potentially fatal dehydration. Two rotavirus vaccines are available for the prevention of rotavirus gastroenteritis, Rotateq and Rotarix. Rotateq is a live vaccine consisting of 5 reassorted human-bovine viral strains. Rotarix is a live attenuated vaccine containing the...
Approved
Matched Description: … [Label] Rotavirus vaccines are 90% effective in protecting against severe rotavirus infection. ... Rotateq is a live vaccine consisting of 5 reassorted human-bovine viral strains. ... [L1117] Two rotavirus vaccines are available for the prevention of rotavirus gastroenteritis, Rotateq …

Golodirsen

Golodirsen is a morpholino antisense oligomer designed to treat about 8% of patients with Duchenne Muscular Dystrophy (DMD). This is an X-linked condition leading to progressive muscle degeneration that begins in early childhood, rendering many patients wheelchair-bound by age 12. Often, patients succumb to this condition by age 30 or...
Approved
Matched Description: … [A188580,T756] A similar drug used in the treatment of other types of DMD is [eteplirsen], which targets ... This is an X-linked condition leading to progressive muscle degeneration that begins in early childhood ... Continued approval of this drug will depend on the results of clinical trials that confirm its clinical …
Matched Categories: … Compounds used in a research, industrial, or household setting …

Adalimumab

Adalimumab is a subcutaneously administered biological disease modifier for the treatment of rheumatoid arthritis and other chronic debilitating diseases mediated by tumor necrosis factor.[A39984,A39999] It was originally launched by Abbvie in the U.S. and approved in 2002 by the FDA. This drug is frequently known as Humira. It is produced...
Approved
Experimental
Matched Description: … Adalimumab is a subcutaneously administered biological disease modifier for the treatment of rheumatoid ... [L49101] A biosimilar marketed as Hyrimoz, a high-concentration formulation of adalimumab, is also available ... [A39984,A39999] It was originally launched by Abbvie in the U.S. and approved in 2002 by the FDA. …
Matched Products: … HULIO 40MG ILO IN FER ... AMGEVITA 40 mg/0.8 ml solution for injection in pre-filled syringe ... IDACIO SOLUTION FOR INJECTION IN PRE-FILLED PEN 40MG/0.8ML …

Beremagene geperpavec

Beremagene geperpavec is a live, replication-defective herpes simplex virus type 1 (HSV-1)-based vector therapy. Developed by Krystal Biotech, it was first approved by the FDA on May 19, 2023, for the treatment of wounds associated with dystrophic epidermolysis bullosa (DEB). DEB is caused by mutations in the COL7A1 gene that...
Approved
Matched Description: … [L46916] DEB is caused by mutations in the _COL7A1_ gene that encodes collagen VII (COL7), a major component ... of the anchoring fibrils for dermal–epidermal cohesion. ... Developed by Krystal Biotech, it was first approved by the FDA on May 19, 2023, for the treatment of …
Matched Categories: … Cellular and Gene Therapy ... Preparations for Treatment of Wounds and Ulcers …

Perindopril

Perindopril is a nonsulfhydryl prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is rapidly metabolized in the liver to perindoprilat, its active metabolite, following oral administration. Perindoprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to...
Approved
Matched Description: … It is rapidly metabolized in the liver to perindoprilat, its active metabolite, following oral administration ... Perindoprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of ... is a nonsulfhydryl prodrug that belongs to the angiotensin-converting enzyme (ACE) inhibitor class of …
Matched Mixtures name: … Viacoram 7 mg/5 mg Tabletten ... VIACORAM TABLET 7 MG/ 5 MG ... COVERAM 7 MG / 5 MG TABLET, 30 ADET …

Tick-borne encephalitis vaccine (whole virus, inactivated)

Tick-borne encephalitis (TBE) is a disease caused by the TBE virus (TBEV), transmitted by ticks from the genus Ixodes. The disease course is variable. Some patients will be asymptomatic or experience a mild febrile illness, while others will experience the full course including neurological symptoms. TBE often manifests in a...
Approved
Matched Description: … [L36120] TICOVAC was granted FDA approval on August 13, 2021.[L36050] ... then a second phase characterized by various neurological symptoms falling under the categorizations of ... [A237520] Due to a paucity of effective safe and effective acute therapeutic agents, vaccination remains …
Matched Products: … FSME-Immun 0,25 ml Junior Injektionssuspension in einer Fertigspritze ... FSME-Immun 0,5 ml Erwachsene Injektionssuspension in einer Fertigspritze …
Displaying drugs 26 - 50 of 10666 in total