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Displaying drugs 26 - 50 of 14364 in total
Bacteria possess a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which is synthesized and remodelled through the action of a family of enzymes known as "penicillin-binding proteins" (PBPs). β-lactam antibiotics, including cephalosporins, are PBP inhibitors that, through inhibition of essential PBPs, result in impaired cell wall homeostasis,...
Approved
Investigational
Matched Synonyms: … Cefixime anhydrous
Matched Description: … , and meningitis. ... a cell wall comprising a glycopeptide polymer commonly known as peptidoglycan, which is synthesized and ... [A232920, A232925, A232930] Cefixime is a broad-spectrum antibiotic and an orally-active third-generation …
Matched Categories: … cefixime and ornidazole ... cefixime and azithromycin …
Approved
Matched Synonyms: … Ferrous gluconate anhydrous ... Iron(II) gluconate, anhydrous
Matched Mixtures name: … Somarexin and C 1000 ... Magnum-75 Vitamin and Mineral Supplement …
Matched Categories: … Blood and Blood Forming Organs ... ferrous gluconate and folic acid …
Nitrofurantoin is a nitrofuran antibiotic used to treat uncomplicated urinary tract infections.[L6856,L6859,L6862] Nitrofurantoin is converted by bacterial nitroreductases to electrophilic intermediates which inhibit the citric acid cycle as well as synthesis of DNA, RNA, and protein. This drug is more resistant to the development of bacterial resistance because it acts...
Approved
Vet approved
Matched Synonyms: … Nitrofurantoin anhydrous ... Nitrofurantoinum anhydrous
Matched Description: … to electrophilic intermediates which inhibit the citric acid cycle as well as synthesis of DNA, RNA, and
Matched Mixtures name: … Nitrofurantoin monohydrate/macrocrystals (monohydrate/macrocrystals) ... Nitrofurantoin monohydrate/macrocrystals (monohydrate/macrocrystals) ... Nitrofurantoin (monohydrate/macrocrystals) …
Matched Salts name: … Nitrofurantoin monohydrate
Dasatinib is an orally available multikinase inhibitor indicated for the treatment of Philadelphia chromosome (Ph)-positive leukemias.[A2224,L45171] Ph is a chromosomal abnormality found in patients with chronic myelogenous leukemia (CML) and acute lymphocytic leukemia (ALL), where the ABL tyrosine kinase and the breakpoint cluster region (BCR) gene transcribe the chimeric protein...
Approved
Investigational
Matched Synonyms: … Anhydrous dasatinib ... Dasatinib anhydrous ... dasatinib (anhydrous) …
Matched Description: … pathogenesis of CML and 15-30% of ALL cases. ... ALL, dasatinib inhibits the active and inactive conformations of the ABL kinase domain. ... acute lymphocytic leukemia (ALL), where the ABL tyrosine kinase and the breakpoint cluster region (BCR …
Matched Salts name: … Dasatinib monohydrate
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Betaine is a methyl group donor that functions in the normal metabolic cycle of methionine. It is a naturally occurring choline derivative commonly ingested through diet, with a role in regulating cellular hydration and maintaining cell function.[A252235,A252240] Homocystinuria is an inherited disorder that leads to the accumulation of homocysteine in...
Approved
Investigational
Nutraceutical
Matched Synonyms: … Betaine, anhydrous
Matched Description: … The FDA and EMA have approved the product Cystadane (betaine anhydrous, oral solution) for the treatment ... of homocystinuria,[L43105,L43115] and the EMA has approved the use of Amversio (betaine anhydrous, oral ... occurring choline derivative commonly ingested through diet, with a role in regulating cellular hydration and
Matched Mixtures name: … Betaine HCl and Pepsin ... Glutamic Acid Pepsin and Betaine Tablets ... Rocky Mountain Multiple Vit and Min Mega Tab …
Matched Categories: … Amino Acids and Derivatives ... Alimentary Tract and Metabolism …
Matched Products: … Betaine Anhydrous ... Betaine Anhydrous For Oral Solution ... Betaine Anhydrous for Oral Solution …
A potent, non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with nucleoside analogues for treatment of Human Immunodeficiency Virus Type 1 (HIV-1) infection and AIDS. Structurally, nevirapine belongs to the dipyridodiazepinone chemical class.
Approved
Matched Synonyms: … Nevirapine anhydrous ... Nevirapine, anhydrous
Matched Description: … combination with nucleoside analogues for treatment of Human Immunodeficiency Virus Type 1 (HIV-1) infection and
Matched Mixtures name: … Lamivudine, Nevirapine, and Zidovudine ... LAMIVUDINE, NEVIRAPINE AND ZIDOVUDINE TABLETS (150/200/300 mg) …
Matched Categories: … stavudine, lamivudine and nevirapine ... zidovudine, lamivudine and nevirapine ... Metabolic Side Effects of Drugs and Substances …
Lanthanum carbonate is a phosphate binder marketed under the trade name Fosrenol by Shire Pharmaceuticals. It is a large pill that requires thorough chewing to avoid choking and other gastrointestinal adverse effects. It is used to treat elevated phosphate levels, primarily in patients with chronic kidney disease, by binding to...
Approved
Matched Synonyms: … Lanthanum carbonate anhydrous
Matched Description: … It is a large pill that requires thorough chewing to avoid choking and other gastrointestinal adverse ... phosphate levels, primarily in patients with chronic kidney disease, by binding to dietary phosphate and
Matched Categories: … Drugs for Treatment of Hyperkalemia and Hyperphosphatemia …
Approved
Investigational
Matched Synonyms: … Autologous dendritic cells pulsed with recombinant human fusion protein (MUCIN1 and Glutathione S Transferase …
A tetracycline analog isolated from the actinomycete streptomyces rimosus and used in a wide variety of clinical conditions.
Approved
Investigational
Vet approved
Matched Synonyms: … Oxytetracycline (anhydrous) …
Matched Description: … A tetracycline analog isolated from the actinomycete streptomyces rimosus and used in a wide variety …
Matched Categories: … Alimentary Tract and Metabolism ... Genito Urinary System and Sex Hormones ... Gynecological Antiinfectives and Antiseptics ... Antiinfectives and Antiseptics for Local Oral Treatment …
Methyldopa, or α-methyldopa, is a centrally acting sympatholytic agent and an antihypertensive agent. It is an analog of DOPA (3,4‐hydroxyphenylanine), and it is a prodrug, meaning that the drug requires biotransformation to an active metabolite for therapeutic effects. Methyldopa works by binding to alpha(α)-2 adrenergic receptors as an agonist, leading...
Approved
Matched Synonyms: … Anhydrous methyldopa ... Methyldopa anhydrous
Matched Description: … Methyldopa, or α-methyldopa, is a centrally acting sympatholytic agent and an antihypertensive agent. ... [A231784] It is an analog of DOPA (3,4‐hydroxyphenylanine), and it is a prodrug, meaning that the drug ... [A1499] Methyldopa exists in two isomers D-α-methyldopa and L-α-methyldopa, which is the active form. …
Matched Mixtures name: … Methyldopa and Hydrochlorothiazide ... Methyldopa and Hydrochlorothiazide ... Methyldopa and Hydrochlorothiazide …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Haemophilus influenzae type b strain 20752 capsular polysaccharide tetanus toxoid conjugate antigen is an active immunization as a booster dose given intramuscularly to pediatric patients who have received a primary series with a Haemophilus b Conjugate Vaccine that is licensed for primarly immunization. The vaccine contains Haemophilus b capsular polysaccharide...
Approved
Investigational
Matched Synonyms: … Haemophilus influenzae type B-PRP and tetanus toxoid conjugate (PRP-T) …
Matched Description: … These are heat inactivated and purified. …
Thrombotic thrombocytopenic purpura (TTP) is a rare blood clotting disorder characterized by thrombocytopenia, microangiopathic hemolytic anemia, and various degrees of organ damage. It may be inherited (congenital TTP; cTTP) or acquired due to autoantibodies (immune-mediated TTP; iTTP), although cTTP accounts for <5% of all cases of TTP. Patients with cTTP...
Approved
Investigational
Matched Synonyms: … Recombinant disintegrin and metalloprotease with thrombospondin type 1 motifs …
Matched Description: … rare blood clotting disorder characterized by thrombocytopenia, microangiopathic hemolytic anemia, and ... Patients with cTTP have a severe deficiency of a plasma metalloproteinase called ADAMTS13 (a disintegrin and ... thrombospondin type 1 motif, member 13), which is responsible for cleaving large von Willebrand factor multimers and
Matched Categories: … Enzymes and Coenzymes ... Blood and Blood Forming Organs ... Amino Acids, Peptides, and Proteins ... apadamtase alfa and cinaxadamtase alfa …
A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant. It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in alcoholic beverages.
Approved
Matched Synonyms: … Alcohol anhydrous
Matched Description: … It has bactericidal activity and is used often as a topical disinfectant. ... A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout ... It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as …
Matched Mixtures name: … Alcohol and Dextrose ... Alcohol and Dextrose ... Alcohol 5% and Dextrose 5% Inj USP …
Matched Categories: … Antiseptics and Disinfectants …
Matched Products: … R and R ... Brompton and Langley Coconut Water and Habiscus Hand Sanitizer Coconut Water and Habiscus ... Brompton and Langley Ginger Lily and Lime Moisturizing Hand Sanitizer ginger lily and lime …
Gibberella fujikuroi allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Molds, rusts and smuts, fusarium moniliforme …
Caffeine is a drug of the methylxanthine class used for a variety of purposes, including certain respiratory conditions of the premature newborn, pain relief, and to combat drowsiness. Caffeine is similar in chemical structure to Theophylline and Theobromine.[A187691,L9851] It can be sourced from coffee beans, but also occurs naturally in...
Approved
Matched Synonyms: … Anhydrous caffeine …
Matched Description: … Caffeine is similar in chemical structure to [Theophylline] and [Theobromine]. ... [A187694] Caffeine is beneficial in preventing and treating apnea and bronchopulmonary dysplasia in newborns ... variety of purposes, including certain respiratory conditions of the premature newborn, pain relief, and
Matched Mixtures name: … dihydrocodeine bitartrate and aspirin and caffeine DC ... Asa and Caffeine ... Ac and C Tab 1/8gr …
Matched Categories: … caffeine and sodium benzoate ... Respiratory and CNS Stimulants ... Caffeine and Caffeine Containing Products ... Anorexigenic Agents & Respiratory and CNS Stimulants ... Psychostimulants, Agents Used for ADHD and Nootropics …
Matched Products: … Caffeine and Sodium Benzoate …
Saxagliptin (rINN) is an orally active hypoglycemic (anti-diabetic drug) of the new dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. FDA approved on July 31, 2009.
Approved
Matched Synonyms: … Saxagliptin anhydrous
Matched Mixtures name: … Saxagliptin and Metformin ... Saxagliptin and Metformin ... Saxagliptin and Metformin …
Matched Salts name: … Saxagliptin monohydrate
Matched Categories: … Alimentary Tract and Metabolism ... metformin and saxagliptin ... Amino Acids, Peptides, and Proteins ... saxagliptin and dapagliflozin ... metformin, saxagliptin and dapagliflozin …
Imipenem is a semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative and gram-positive aerobic and anaerobic bacteria, including many multiresistant strains.[label] It is stable to many beta-lactamases. Similar compounds include meropenem, known for having greater activity against Gram negative bacteria, and the newer ertapenem which exhibits...
Approved
Matched Synonyms: … Imipenem anhydrous
Matched Description: … gram-positive aerobic and anaerobic bacteria, including many multiresistant strains. ... product with cilastatin and [relebactam] which was recently approved by the FDA. ... semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative and
Matched Mixtures name: … IMIPENEM MONOHYDRATE - CILASTATIN SODIUM ... IMIPENEM MONOHYDRATE / CILASTATIN SODIUM ... Imipenem and Cilastatin …
Matched Salts name: … Imipenem monohydrate
Matched Categories: … imipenem and cilastatin ... imipenem, cilastatin and relebactam …
Elapegademase is a PEGylated recombinant adenosine deaminase. It can be defined molecularly as a genetically modified bovine adenosine deaminase with a modification in cysteine 74 for serine and with about 13 methoxy polyethylene glycol chains bound via carbonyl group in alanine and lysine residues. Elapegademase is generated in E. coli,...
Approved
Matched Synonyms: … PEPTIDE PRODUCED IN ESCHERICHIA COLI, AN AVERAGE OF 13 RESIDUES ARE SUBSTITUTED ON N.ALPHA..1ALANINE AND ... 356)-PEPTIDE, PRODUCED IN ESCHERICHIA COLI, SUBSTITUTED ON N2 OF THE N-TERMINAL ALANYL RESIDUE (A1) AND
Matched Description: … as a genetically modified bovine adenosine deaminase with a modification in cysteine 74 for serine and ... [F1937] Elapegademase is generated in _E. coli_, developed by Leadiant Biosciences and FDA approved on ... with about 13 methoxy polyethylene glycol chains bound via carbonyl group in alanine and lysine residues …
Matched Categories: … Enzymes and Coenzymes ... Amino Acids, Peptides, and Proteins ... Antineoplastic and Immunomodulating Agents …
Mucor circinelloides f. circinelloides allergenic extract is used in allergenic testing.
Approved
Matched Synonyms: … Molds, rusts and smuts, mucor circinelloides f. circinelloides …
Cefoxitin is a semi-synthetic, broad-spectrum cepha antibiotic for intravenous administration. It is derived from cephamycin C, which is produced by Streptomyces lactamdurans.
Approved
Matched Products: … Cefoxitin and Dextrose
Labetalol is a racemic mixture of 2 diastereoisomers where dilevalol, the R,R' stereoisomer, makes up 25% of the mixture. Labetalol is formulated as an injection or tablets to treat hypertension.[L7727,L7730] Labetalol was granted FDA approval on 1 August 1984.
Approved
Matched Categories: … Alpha and Beta Blocking Agents and Thiazides ... labetalol and thiazides ... Alpha and Beta Blocking Agents ... labetalol and other diuretics ... Beta Blocking Agents and Thiazides …
Matched Products: … Labetalol HCl in Dextrose ... BLOCAMINE (Labetalol hydrochloride 5 mg/ml solution for Injection and for Infusion) …
Unfractionated heparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers with weights ranging from 3000 to 30,000 Da. It is a naturally occurring anticoagulant released from mast cells. It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin (factor...
Approved
Investigational
Matched Description: … coagulation enzymes thrombin (factor IIa) and factor Xa. ... UH has a higher risk of bleeding and higher risk of osteoporosis in long term use. ... It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates …
Matched Mixtures name: … Heparin Sodium and Dextrose 5% Inj USP ... Heparin Sod and 0.9% Sod Chloride Inj ... Heparin Sodium in Dextrose
Matched Categories: … Heparin and similars ... Blood and Blood Forming Organs …
Matched Products: … Heparin Sodium and Dextrose ... Heparin Sodium in Dextrose ... Heparin Sodium and Sodium Chloride …
Doripenem is a broad-spectrum, carbapenem antibiotic marketed under the brand name Doribax by Janssen. Doripenem injection was approved by the FDA in 2007 to treat complicated urinary tract and intra-abdominal infections. In a clinical trial of doripenem treatment in ventilator associated pneumonia (vs. imipenem and cilastatin), it was found that...
Approved
Investigational
Matched Description: … to reiterate its safety and efficacy for its approved indications. ... Doripenem injection was approved by the FDA in 2007 to treat complicated urinary tract and intra-abdominal ... In a clinical trial of doripenem treatment in ventilator associated pneumonia (vs. imipenem and cilastatin …
Matched Products: … DORIPENEM MONOHYDRATE
Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is...
Approved
Matched Description: … Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic ... It is also found in plants and is used pharmacologically as a sympathomimetic. ... Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse …
Matched Categories: … Epinephrine and similars ... Adrenergic and Dopaminergic Agents ... Alpha-and Beta-adrenergic Agonists …
Matched Products: … NOREPINEPHRINE BITARTRATE MONOHYDRATE ... Norepinephrine Bitartrate In 5% Dextrose Injection …
The chemical compound calcium acetate is the calcium salt of acetic acid. It has been commonly referred to as the acetate of lime. The anhydrous form is very hygroscopic, therefore the monohydrate is the common form.
Approved
Investigational
Matched Description: … The anhydrous form is very hygroscopic, therefore the monohydrate is the common form. …
Matched Salts name: … Calcium acetate monohydrate
Matched Categories: … Alimentary Tract and Metabolism ... ascorbic acid (vit C) and calcium ... calcium acetate and magnesium carbonate ... Drugs for Treatment of Hyperkalemia and Hyperphosphatemia …
Displaying drugs 26 - 50 of 14364 in total