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Displaying drugs 476 - 500 of 2397 in total

Emapalumab

Emapalumab, also known as NI-0501, is a fully human monoclonal antibody that targets interferon gamma. Emapalumab development was sponsored by NovImmune SA, further developed by Sobi and FDA approved on November 20, 2018.[A38676, L4840] The approval of emapalumab was followed by the designation of orphan drug, priority review and breakthrough...
Approved
Investigational

Carbocisteine

Dyspnea and cough are common symptoms of chronic obstructive pulmonary disease (COPD) and other respiratory conditions characterized by increased mucus production. Individuals with COPD have a greater risk of pulmonary infection due to the growth and accumulation of viruses and bacteria in thick bronchial mucus. Carbocisteine is a mucolytic drug...
Approved
Investigational
Matched Products: … SCMC SYRUP 100 100 mg/5 ml ... MUCOSIS 100 MG/5 ML PEDİYATRİK ŞURUP, 100 ML ... MUKOTIK ÇOCUK ŞURUBU 100 MG/5ML, 100 ML …

Fluorouracil

A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the thymidylate synthetase conversion of deoxyuridylic acid to thymidylic acid.
Approved
Matched Mixtures name: … Actikerall 5 mg/g + 100 mg/g Lösung zur Anwendung auf der Haut …
Matched Products: … FLUOROURACIL HEX 5000/100 ... FLURO-5 DEVA 5000 MG/100 ML IV/IA ENJEKSİYONLUK/İNFÜZYONLUK ÇÖZELTİ, 1 ADET ... 5-FLUOROURACIL EBEWE 5000 MG/100 ML ENJ. ICIN COZ. ICEREN FLAKON, 1 ADET …

Procaine

A local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1016). Procaine has also been investigated as an oral entry inhibitor in...
Approved
Investigational
Vet approved
Matched Products: … NTCAIN 100 MG/10 ML IM AMPUL, 100 ADET ... NTCAIN 100 MG/10 ML IM AMPUL, 10 ADET ... NTCAIN 50 MG/5 ML IM AMPUL , 100 ADET …

Pemetrexed

Pemetrexed is a chemotherapy drug that is manufactured and marketed by Eli Lilly and Company under the brand name Alimta. It is indicated for use in combination with cisplatin for the treatment of patients with malignant pleural mesothelioma whose disease is either unresectable or who are otherwise not candidates for...
Approved
Investigational
Matched Salts cas: … 1645228-03-0 …
Matched Products: … PRIMEXA 100 ... PEMEXEN 100 ... PEMCORD 100 …

Lithium carbonate

Lithium has been used to treat manic episodes since the 19th century . Though it is widely used, its mechanism of action is still unknown[FDA Label][A14585,A176642,A176651,L5843]. Lithium carbonate has a narrow therapeutic range and so careful monitoring is required to avoid adverse effects[FDA Label].
Approved
Matched Products: … LITHURIL 300 MG KAPSUL, 100 ADET ... LİTOMAKS 300 MG SERT KAPSÜL, 100 ADET …

Piperazine

Piperazine is an organic compound that consists of a six-membered ring containing two opposing nitrogen atoms. First used as a solvent for uric acid, the use of piperazine as an anthelmintic agent was first introduced in 1953. Upon entry into the systemic circulation, the drug is partly oxidized and partly...
Approved
Vet approved
Matched Salts cas: … 142-63-2 ... 3597-26-0 …
Matched Products: … ASEPAR 100 MG 100 ML SURUP ... BERAZIN SURUP,100 ML ... PİPEZOL SURUP, 100 ML …

Desflurane

Desflurane, or I-653, a a volatile anesthetic that is more rapidly cleared and less metabolized than previous inhaled anesthetics such as methoxyflurane, sevoflurane, enflurane, or isoflurane.[A226390,A39015,A226893]. It was developed in the late 1980s out of a need for a more rapidly acting and rapidly cleared inhaled anesthetic.[A226883,A226888] Desflurane was granted...
Approved
Matched Products: … DESJOURN % 100 İNHALASYON ÇÖZELTISI , 250 ML ... SUPRANE VOLATİL %100 İNHALASYON BUHARI, ÇÖZELTİ, 240 ML ... Desfluran Piramal 100 % (v/v) Flüssigkeit zur Herstellung eines Dampfs zur Inhalation …

Amphotericin B

Amphotericin B shows a high order of in vitro activity against many species of fungi. Histoplasma capsulatum, Coccidioides immitis, Candida species, Blastomyces dermatitidis, Rhodotorula, Cryptococcus neoformans, Sporothrix schenckii, Mucor mucedo, and Aspergillus fumigatus are all inhibited by concentrations of amphotericin B ranging from 0.03 to 1.0 mcg/mL in vitro. While...
Approved
Investigational
Matched Products: … Amphotec 100 mg ... ABELCET 100 MG/20 ML IV INF. ICIN. SUS. ICEREN FLAKON, 1 ADET …

Fluciclovine (18F)

Fluciclovine is a [18F]-tagged synthetic analog of the amino acid L-leucine. It presents excellent diagnostic properties to be used in positron emission tomography (PET) imaging. The structure of fluciclovine allows it to be uptaken by the tumoral cells by its amino acid transporter without incorporating in the metabolism within the...
Approved

Sumatriptan

Sumatriptan is a serotonin receptor agonist commonly used to treat migraines and sometimes cluster headaches.[L6793,L6796,L6799,L6805,L6808,L6811] Sumatriptan is the first of the triptans and was made available in Europe in 1991 to treat migraines. Sumatriptan was granted FDA approval on 28 December 1992.
Approved
Investigational
Matched Salts cas: … 143675-45-0 …
Matched Products: … SUMALUX ®100 MG ... IMIGRAN 100 MGTABLETAS ... SUTRIP 100 MG TABLET, 2 ADET …

Venetoclax

Venetoclax is a BCL-2 inhibitor that was initially approved by the FDA in April 2016 [FDA label]. Proteins in the B cell CLL/lymphoma 2 (BCL-2) family are important regulators of the apoptotic (programmed cell death) process , . Venetoclax is used to treat chronic lymphocytic leukemia (CLL) and certain types...
Approved
Investigational
Matched Products: … เว็นเคล็กซ์ต้า (100 มิลลิกรัม) ... VENCLYXTO 100 MG FILM KAPLI TABLET, 7 ADET ... VENCLYXTO 100 MG FILM KAPLI TABLET, 14 ADET …

Estradiol

Estradiol is a naturally occurring hormone circulating endogenously in females. It is commercially available in several hormone therapy products for managing conditions associated with reduced estrogen, such as vulvovaginal atrophy and hot flashes. Some available forms of estradiol include oral tablets, injections, vaginal rings, transdermal patches, sprays, gels, and creams.[L11485,L11488,L11491,...
Approved
Investigational
Vet approved
Matched Products: … Climara 100 ... Estradot 100 ... ESTRAMON 100 …

Trimebutine

Trimebutine is a spasmolytic agent that regulates intestinal and colonic motility and relieves abdominal pain with antimuscarinic and weak mu opioid agonist effects. It is marketed for the treatment of irritable bowel syndrome (IBS) and lower gastrointestinal tract motility disorders, with IBS being one of the most common multifactorial GI...
Approved
Matched Mixtures name: … LIBERTRIM® SII 100 MG …
Matched Products: … DEBRIDAT TABLET 100 mg ... CEREKINON TABLET 100 mg ... DEBRIDAT 100 MG TABLET, 20 ADET …

Iopromide

Iopromide is a low osmolar, non-ionic X-ray contrast agent for intravascular administration. It functions as a contrast agent by opacifying blood vessels in the flow path of the contrast agent, permitting radiographic visualization of the internal structures until significant hemodilution occurs. Although iopromide can cause several serious adverse effects, including...
Approved
Matched Products: … VİSGRAF 370 MGI/ML ENJEKSİYONLUK ÇÖZELTİ, 100 ML ... İOPOLİMİD 370 MG I/ML ENJEKSİYONLUK ÇÖZELTİ, 100 ML ... İOPOLİMİD 300 MGI/ML ENJEKSİYONLUK ÇÖZELTİ, 100 ML …

Fedratinib

Fedratinib, also known as SAR302503 and TG101348, is a tyrosine kinase inhibitor used to treat intermediate-2 and high risk primary and secondary myelofibrosis.[A183176,L8090] It is an anilinopyrimidine derivative. Fedratinib was granted FDA approval on August 16, 2019.
Approved
Investigational
Matched Salts cas: … 1374744-69-0 …
Matched Products: … Inrebic 100 mg capsules ... Inrebic 100 mg Sert Kapsül, 120 ADET …

Fenofibrate

Fenofibrate is a fibric acid derivative like clofibrate and gemfibrozil. Fenofibrate is used to treat primary hypercholesterolemia, mixed dyslipidemia, severe hypertriglyceridemia.[L8588,L8591] Fenofibrate was granted FDA approval on 31 December 1993.
Approved
Matched Products: … TROLIP 100 ... LIPANTHYL 100 ... เลซีมิน 100 …

Methotrimeprazine

A phenothiazine with pharmacological activity similar to that of both chlorpromazine and promethazine. It has the histamine-antagonist properties of the antihistamines together with central nervous system effects resembling those of chlorpromazine. (From Martindale, The Extra Pharmacopoeia, 30th ed, p604)
Approved
Investigational
Matched Products: … LEVOMEPROMAZIN-NEURAX 100 ... SINOGAN® 100 MG TABLETAS. ... Nozinan 100 mg - Filmtabletten …

Ceftobiprole medocaril

Ceftobiprole medocaril is a prodrug of ceftobiprole, a fifth-generation semisynthetic cephalosporin antibacterial. Ceftobiprole is a broad-spectrum agent with demonstrated activity against both Gram-positive and Gram-negative bacteria, including antibiotic-resistant strains of Staphylcoccus aureus (methicillin-resistant Staphylococcus aureus; MRSA). The EMA's Committee for Medicinal Products for Human Use (CHMP) adopted a negative opinion...
Approved
Experimental
Investigational

Temozolomide

Refractory anaplastic astrocytoma (WHO grade III) and Glioblastoma multiforme (WHO grade IV) are primary malignant brain tumours with poor prognosis and limited treatment options. Despite considerable genetic heterogeneity, these tumours often have impaired DNA repair systems, rendering them initially sensitive to alkylating agents, although they invariably develop resistance to these...
Approved
Investigational
Matched Products: … GLIOTEM 100 CAPSULE 100 MG ... TEMOTERO 100 ... โซโลเทม - 100 …

Flecainide

Flecainide is a Class I anti-arrhythmic agent like encainide and propafenone. Flecainide’s development began in 1966 and was first synthesized in 1972 as an attempt to generate new anesthetics. It is used to prevent supraventricular and ventricular arrhythmias, as well as paroxysmal atrial fibrillation and flutter.[L8878,L5056] Flecainide was granted FDA...
Approved
Withdrawn
Matched Products: … TAMBOCOR (TABLET 100 MG) ... TAMBOCOR TABLET 100 mg ... FLECAINIDACETAT PUREN 100 …

Chenodeoxycholic acid

Chenodeoxycholic acid (or Chenodiol) is an epimer of ursodeoxycholic acid (DB01586). Chenodeoxycholic acid is a bile acid naturally found in the body. It works by dissolving the cholesterol that makes gallstones and inhibiting production of cholesterol in the liver and absorption in the intestines, which helps to decrease the formation...
Approved
Matched Products: … CETEİX 250 MG SERT KAPSÜL, 100 ADET ... KENDEO 250 MG SERT KAPSÜL, 100 ADET …

Docusate

Docusate, or dioctyl sulfosuccinate, is a stool softener indicated for the treatment of constipation . Docusate acts by increasing the amount of water the stool absorbs in the gut, making the stool softer and easier to pass . Docusate can be orally or rectally administered. Docusate is on the World...
Approved
Matched International brands: … Docusol 100 …
Matched Salts cas: … 7491-09-0 …
Matched Products: … Laxa-basic 100 ... มอร์กาแล็กซ์ 100 ... M-docusate Sodium 100 mg …

Etravirine

Etravirine is an antiretroviral agent more specifically classified as a Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI). Etraverine is used clinically for the treatment of human immunodeficiency virus type 1 (HIV-1) infection. On January 18, 2007, the FDA granted accelerated approved for the use of etravirine 100mg tablets in the treatment of...
Approved
Matched Products: … INTELENCE 100 MG TABLETS ... INTELENCE 100 MG TABLET, 120 ADET …

Pembrolizumab

Pembrolizumab is a highly selective IgG4-kappa humanized monoclonal antibody against PD-1 receptors. It was generated by grafting the variable sequences of a very high-affinity mouse antihuman PD-1 antibody onto a human IgG4-kappa isotype containing a stabilizing S228P Fc mutation. It contains 32 cysteine residues and the complete folded molecule includes...
Approved
Matched Products: … KEYTRUDA® 100 MG ... KEYTRUDA 100 MG/4 ML IV INFUZYONLUK COZELTI İÇEREN FLAKON, 1 ADET …
Displaying drugs 476 - 500 of 2397 in total