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Displaying drugs 476 - 500 of 12915 in total
Chlorhexidine is a broad-spectrum antimicrobial biguanide used as a topical antiseptic and in dental practice for the treatment of inflammatory dental conditions caused by microorganisms. It is one of the most common skin and mucous membrane antiseptic agents in use today. The molecule itself is a cationic bis-guanide consisting of...
Approved
Vet approved
Withdrawn
Matched Iupac: … N-(4-chlorophenyl)-1-{N'-[6-(N-{[N'-(4-chlorophenyl)carbamimidamido]methanimidoyl}amino)hexyl]carbamimidamido …
Matched Description: … Chlorhexidine is a broad-spectrum antimicrobial biguanide used as a topical antiseptic and in dental ... biguanide groups joined by a central hexamethylene chain. ... [A190417] The molecule itself is a cationic bis-guanide consisting of two 4-chlorophenyl rings and two …
Matched Salts cas: … 56-95-1
Matched Mixtures name: … 3เอ็ม ซีเอชจี แพด ... CLIORO ORAL SPREY, 1 ADET ... KLOROBEN FORT 3 MG/ML+ 2 MG/ML GARGARA, 200 ML …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Matched Products: … Alsoft A Hand Disinfectant 0.2% w/v ... Prevora Stage 1 ... Hexigel 1% w/w …
A glutamate antagonist (receptors, glutamate) used as an anticonvulsant (anticonvulsants) and to prolong the survival of patients with amyotrophic lateral sclerosis. Riluzole is marketed as Rilutek by Sanofi.
Approved
Investigational
Matched Description: … A glutamate antagonist (receptors, glutamate) used as an anticonvulsant (anticonvulsants) and to prolong …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Compounds used in a research, industrial, or household setting …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Switzerland/9715293/2013 NIB-88 (H3N2) antigen (UV, formaldehyde inactivated) …
Matched Description: … , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... A seasonally-specific component of the influenza vaccine. ... The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from …
Bifonazole is an azole antifungal drug.
Approved
Investigational
Matched Synonyms: … (+-)-1-(p,alpha-Diphenylbenzyl)imidazole ... 1-(p,alpha-Diphenylbenzyl)imidazole ... 1-(alpha-(4-Biphenylyl)benzyl)imidazole …
Matched Iupac: … 1-({[1,1'-biphenyl]-4-yl}(phenyl)methyl)-1H-imidazole …
Matched Mixtures name: … CANESTEN ULTRA UÑAS 1% …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … ANTIZOX® 1% CREMA ... MYCOSPOR POLVO 1 G. ... MYCOSPOR POLVO AL 1% …
Tixocortol is a 21-thiol derivative of hydrocortisone classified as a class A corticosteroid. It is a synthetic steroid with topical anti-inflammatory properties without the systemic glucocorticoid and mineralocorticoid activities and toxicity.
Approved
Withdrawn
Matched Description: … Tixocortol is a 21-thiol derivative of hydrocortisone classified as a class A corticosteroid. ... It is a synthetic steroid with topical anti-inflammatory properties without the systemic glucocorticoid …
Alginic acid, also referred to as algin or alginate, is a hydrophilic or anionic polysaccharide isolated from certain brown seaweed (Phacophycae) via alkaline extraction. It is present in cell walls of brown algae where it forms a viscous gel when binding with water. Alginic acid is a linear polymer consisted...
Approved
Investigational
Matched Synonyms: … (Alginate)n+1
Matched Description: … Alginic acid, also referred to as algin or alginate, is a hydrophilic or anionic polysaccharide isolated ... It is present in cell walls of brown algae where it forms a viscous gel when binding with water. ... Alginic acid is a linear polymer consisted of L-glucuronic acid and D-mannuronic acid residues connected …
Matched Salts cas: … 9005-38-3
Matched Mixtures name: … SUSPENSION ORAL CON SABOR A MENTA ... SUSPENSION ORAL CON SABOR A MENTA ... GAVISCON® TABLETAS MASTICABLES SABOR A MENTA …
Matched Categories: … Compounds used in a research, industrial, or household setting …
Bacitracin is a combination of at least 9 bacitracins.[A955,A181952] 60-80% of commercially prepared bacitracin is bacitracin A. The bacillus that produces bacitracin was first isolated from a knee scrape in 1945 from the knee wound of a child named Margaret Tracy. Bacitracin was granted FDA approval on 29 July 1948.[A181997,L7748]
Approved
Vet approved
Matched Synonyms: … Bacitracin A
Matched Iupac: … ]-4-{[(1S,2S)-1-{[(3S,6R,9S,12R,15S,18R,21S)-18-(3-aminopropyl)-12-benzyl-15-[(2S)-butan-2-yl]-3-(carbamoylmethyl ... (4R)-4-[(2S)-2-{[(4R)-2-[(1S,2S)-1-amino-2-methylbutyl]-4,5-dihydro-1,3-thiazol-4-yl]formamido}-4-methylpentanamido …
Matched Description: … knee wound of a child named Margaret Tracy. ... Bacitracin is a combination of at least 9 bacitracins. ... [A955,A181952] 60-80% of commercially prepared bacitracin is bacitracin A. …
Matched Salts cas: … 55852-84-1
Matched Mixtures name: … Water-Jel 3-in-1 Antibiotic ... Zee 3-in-One First Aid Antibiotic ... Band-aid-S-1
Human African trypanosomiasis (HAT, also colloquially referred to as sleeping sickness), caused by T. brucei gambiense and T. brucei rhodesiense, remains a moderate risk (>1/10,000 inhabitants per year in endemic areas) despite focussed control efforts. Transmitted by the bite of an infected tsetse fly, HAT is biphasic with a first...
Approved
Investigational
Matched Iupac: … 1-methyl-2-{[4-(methylsulfanyl)phenoxy]methyl}-5-nitro-1H-imidazole …
Matched Description: … moderate risk (>1/10,000 inhabitants per year in endemic areas) despite focussed control efforts. ... referred to as sleeping sickness), caused by _T. brucei gambiense_ and _T. brucei rhodesiense_, remains a ... Transmitted by the bite of an infected tsetse fly, HAT is biphasic with a first (hemolymphatic) stage …
Matched Categories: … MATE 1 Inhibitors ... Heterocyclic Compounds, 1-Ring ... Organic Anion Transporter 1 Inhibitors …
Tovorafenib is a selective type II RAF kinase inhibitor with anti-tumour activity. It was granted accelerated approval by the FDA, making it the first FDA approval of a systemic therapy for the treatment of pediatric low-grade glioma, with BRAF rearrangements. BRAF oncogenic mutations in cancers drive dysregulated cell growth, proliferation,...
Approved
Investigational
Matched Synonyms: … 4-Pyrimidinecarboxamide, 6-amino-5-chloro-N-[(1R)-1-[5-[[[5-chloro-4-(trifluoromethyl)-2-pyridinyl]amino ... 6-Amino-5-chloro-N-((1R)-1-(5-(((5-chloro-4-(trifluoromethyl)-2-pyridinyl)amino)carbonyl)-2-thiazolyl ... 6-amino-5-chloro-N-[1R)-1-[5-[[[5-hloro-4-(trifluoromethyl)-2pyridinyl]amino]carbonyl]-2-thiazoyl]ethyl …
Matched Iupac: … 6-amino-5-chloro-N-[(1R)-1-(5-{[5-chloro-4-(trifluoromethyl)pyridin-2-yl]carbamoyl}-1,3-thiazol-2-yl) …
Matched Description: … Tovorafenib is a selective type II RAF kinase inhibitor with anti-tumour activity. ... [A263597] It was granted accelerated approval by the FDA, making it the first FDA approval of a systemic …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Ramelteon is the first in a new class of sleep agents that selectively binds to the melatonin receptors in the suprachiasmatic nucleus (SCN). It is used for insomnia, particularly delayed sleep onset. Ramelteon has not been shown to produce dependence and has shown no potential for abuse.
Approved
Investigational
Matched Description: … Ramelteon is the first in a new class of sleep agents that selectively binds to the melatonin receptors …
Anthrax vaccine is a vaccine used for the pre- or post-exposure prophylaxis of disease in those at high risk of, suspected or confirmed exposure to Bacillus anthracis. It is subcutaneously or intramuscularly administered. It is derived from cell-free filtrates of microaerophilic cultures of an avirulent, nonencapsulated strain of Bacillus anthracis...
Approved
Matched Description: … [L47526] It is considered one of the most likely agents to be used in a biological attack. ... Anthrax vaccine is a vaccine used for the pre- or post-exposure prophylaxis of disease in those at high ... microaerophilic cultures of an avirulent, nonencapsulated strain of Bacillus anthracis which are grown in a
Cortisone acetate was first isolate in 1935 and became more widely researched in 1949. Since then, glucocorticoids such as cortisone acetate have been used to treat a number of inflammatory conditions such as endocrine, rheumatic, collagen, dermatologic, allergic, ophthalmic, respiratory, hematologic, neoplastic, edematous, and gastrointestinal diseases and disorders.[A226300,L13203] Cortisone acetate...
Approved
Investigational
Matched Iupac: … ,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl]-2-oxoethyl acetate ... 2-[(1R,3aS,3bS,9aR,9bS,11aS)-1-hydroxy-9a,11a-dimethyl-7,10-dioxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH …
Matched Description: … [A226295] Since then, glucocorticoids such as cortisone acetate have been used to treat a number of inflammatory …
Plecanatide is a drug approved in January 2017 by the FDA for the treatment of chronic idiopathic constipation (CIC). It should not be used in children less than six years of age, and should be avoided in patients six years to 18 years of age
Approved
Investigational
Matched Iupac: … (4S)-4-{[(2S)-2-{[(2S)-2-amino-1-hydroxy-3-(C-hydroxycarbonimidoyl)propylidene]amino}-3-carboxy-1-hydroxypropylidene ... ]amino}-4-{[(1R,4S,7S,10S,13S,16R,19S,22S,25R,32S,38R)-38-{[(1S)-1-carboxy-3-methylbutyl]-C-hydroxycarbonimidoyl ... carboxyethyl)-3,6,9,12,15,18,21,24,30,33,36-undecahydroxy-10-[(C-hydroxycarbonimidoyl)methyl]-32-[(1R)-1- …
Matched Description: … Plecanatide is a drug approved in January 2017 by the FDA for the treatment of chronic idiopathic constipation …
Capecitabine is an orally-administered chemotherapeutic agent used in the treatment of metastatic breast and colorectal cancers. Capecitabine is a prodrug, that is enzymatically converted to fluorouracil (antimetabolite) in the tumor, where it inhibits DNA synthesis and slows growth of tumor tissue.
Approved
Investigational
Matched Synonyms: … pentyl 1-(5-deoxy-β-D-ribofuranosyl)-5-fluoro-1,2-dihydro-2-oxo-4-pyrimidinecarbamate ... Pentyl [1-(5-deoxy-β-D-ribofuranosyl)-5-fluoro-2-oxo-1,2-dihydropyrimidin-4-yl]carbamate ... (1-(5-Deoxy-beta-D-ribofuranosyl)-5-fluoro-1,2-dihydro-2-oxo-4-pyrimidinyl)-carbamic acid pentyl ester …
Matched Iupac: … pentyl N-{1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methyloxolan-2-yl]-5-fluoro-2-oxo-1,2-dihydropyrimidin-4-yl …
Matched Description: … Capecitabine is a prodrug, that is enzymatically converted to fluorouracil (antimetabolite) in the tumor …
Matched Categories: … Heterocyclic Compounds, 1-Ring ... Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index …
Fibrodysplasia Ossificans Progressiva (FOP), with an estimated worldwide prevalence of one in 2 million individuals, is an exceptionally rare genetic disorder. FOP is caused by a gain-of-function mutation in the ACVR1/ALK2 gene which results in progressive heterotopic ossification, a process wherein connective tissues (e.g. skeletal muscle, ligaments, tendons) are replaced...
Approved
Investigational
Matched Iupac: … 4-[(1E)-2-{5,5,8,8-tetramethyl-3-[(1H-pyrazol-1-yl)methyl]-5,6,7,8-tetrahydronaphthalen-2-yl}ethenyl] …
Matched Description: … It first garnered interest as a potential treatment for emphysema but was eventually recognized as a ... ], which are derivatives of [vitamin A]. ... [A244920] FOP is caused by a gain-of-function mutation in the ACVR1/ALK2 gene which results in progressive …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Iptacopan is a small-molecule factor B inhibitor previously investigated as a potential treatment for the rare blood disease paroxysmal nocturnal hemoglobinuria (PNH) by inhibiting the complement factor B. Factor B is a positive regulator of the alternative complement pathway, where it activates C3 convertase and subsequently C5 convertase. This is...
Approved
Investigational
Matched Synonyms: … 4-((2S,4S)-4-ethoxy-1-((5-methoxy-7-methyl-1H-indol-4-yl)methyl)piperidin-2-yl) benzoic acid ... BENZOIC ACID, 4-((2S,4S)-4-ETHOXY-1-((5-METHOXY-7-METHYL-1H-INDOL-4-YL)METHYL)-2-PIPERIDINYL)- …
Matched Iupac: … 4-[(2S,4S)-4-ethoxy-1-[(5-methoxy-7-methyl-1H-indol-4-yl)methyl]piperidin-2-yl]benzoic acid …
Matched Description: … Iptacopan is a small-molecule factor B inhibitor previously investigated as a potential treatment for ... [A262566] Factor B is a positive regulator of the alternative complement pathway, where it activates ... from the phase III APPL-PNH and APPOINT-PNH studies, where 82.3% and 77.5% of patients experienced a
Matched Salts cas: … 2447007-60-3
Nifedipine, or BAY a 1040, is a first generation dihydropyridine L-type calcium channel blocker, similar to nicardipine.[A190210,A190273,A175390,L11383] Nifedipine was developed by Bayer and first described in the literature, along with other dihydropyridines, in 1972.[A175390,A190276] Since nifedipine's development, second and third generation dihydropyridines have been developed with slower onsets and longer...
Approved
Matched Description: … Nifedipine, or BAY a 1040, is a first generation dihydropyridine L-type calcium channel blocker, similar …
Matched Categories: … Heterocyclic Compounds, 1-Ring …
Matched Products: … ANHITEN-A
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Hong Kong/4801/2014 X-263B (H3N2) hemagglutinin antigen (propiolactone inactivated …
Matched Description: … , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... A seasonally-specific component of the influenza vaccine. ... The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Name: … Influenza A virus A/Singapore/GP2050/2015 (H3N2) antigen (MDCK cell derived, propiolactone inactivated …
Matched Description: … , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... A seasonally-specific component of the influenza vaccine. ... The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from …
Levomilnacipran is a selective serotonin and norepinephrine reuptake inhibitor (SNRI), although it is a more potent inhibitor of norepinephrine reuptake than serotonin reuptake.[A261181, A38560] Levomilnacipran is the more active 1S,2R-enantiomer in the racemate milnacipran.[A261181, L47956] Once administered, interconversion between levomilnacipran and its stereoisomer does not occur in humans. First approved...
Approved
Investigational
Matched Synonyms: … CYCLOPROPANECARBOXAMIDE, 2-(AMINOMETHYL)-N,N-DIETHYL-1-PHENYL-, (1S,2R)- …
Matched Iupac: … (1S,2R)-2-(aminomethyl)-N,N-diethyl-1-phenylcyclopropane-1-carboxamide …
Matched Description: … a more potent inhibitor of norepinephrine reuptake than serotonin reuptake. ... Levomilnacipran is a selective serotonin and norepinephrine reuptake inhibitor (SNRI), although it is ... [L47956] While levomilnacipran was previously investigated and proposed as a potential treatment for …
Selenious acid is the acid form of sodium selenite, a form of selenium . Selenium is an essential trace element and antioxidant. It is a cofactor metabolic enzyme regulation. It also plays an important role in maintaining the general health of tissue and muscle and has antioxidant properties. Selenium is...
Approved
Investigational
Matched Description: … It is a cofactor metabolic enzyme regulation. ... Selenious acid is the acid form of sodium selenite, a form of selenium [L1910]. ... Selenium is a component of glutathione peroxidase enzyme, which protects cell components from oxidative …
Matched Salts cas: … 26970-82-1
Matched Mixtures name: … Vege 1 Daily Tab …
Aluminum hydroxide is an inorganic salt used as an antacid. It is a basic compound that acts by neutralizing hydrochloric acid in gastric secretions. Subsequent increases in pH may inhibit the action of pepsin. An increase in bicarbonate ions and prostaglandins may also confer cytoprotective effects.
Approved
Investigational
Matched Iupac: … aluminium(3+) trihydroxide …
Matched Description: … It is a basic compound that acts by neutralizing hydrochloric acid in gastric secretions. …
Matched Salts cas: … 66827-12-1
Matched Mixtures name: … NOAX 3 ... ซีมาเจล 1
Vinorelbine is an anti-mitotic chemotherapy drug that is used in the treatment of several types of malignancies, including breast cancer and non-small cell lung cancer (NSCLC) . It was initially approved in the USA in 1990's for the treatment of NSCLC . It is a third-generation vinca alkaloid. The introduction...
Approved
Investigational
Matched Iupac: … ethyl-4-[(12S,14R)-16-ethyl-12-(methoxycarbonyl)-1,10-diazatetracyclo[12.3.1.0^{3,11}.0^{4,9}]octadeca-3( …
Matched Description: … It is a third-generation vinca alkaloid. ... was found that there was 4.3-fold variation in vinorelbine clearance across the cohort, suggesting a ... A study was done on the clearance rate of vinorelbine on individuals with various single polymorphonuclear …
Matched Salts cas: … 125317-39-7 …
Matched Categories: … Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index …
Matched Products: … RENOVEL 10 MG/1 ML IV ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 1 ADET ... NAVELBINE 20 MG YUMUSAK KAPSUL, 1 ADET ... NAVELBINE 30 MG YUMUSAK KAPSUL, 1 ADET …
Rose bengal is a pink stain derived as an analogue of fluorescein. Its disodium salt in ophthalmic solutions has been used as a diagnostic agent in suspected damage to conjunctival and corneal cells. It is also used in laboratory settings, including the preparation of Foraminifera for microscopic analysis and suppression...
Approved
Investigational
Matched Iupac: … 2,3,4,5-tetrachloro-6-(6-hydroxy-2,4,5,7-tetraiodo-3-oxo-3H-xanthen-9-yl)benzoic acid …
Matched Description: … Rose bengal is a pink stain derived as an analogue of fluorescein. ... Its disodium salt in ophthalmic solutions has been used as a diagnostic agent in suspected damage to ... A direct cytotoxic effect of Rose bengal on microorganisms and cancer cells has been observed, questioning …
Matched Categories: … Heterocyclic Compounds, 3-Ring ... Compounds used in a research, industrial, or household setting …
A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence...
Approved
Matched Description: … , or inactivated, through exposure to heat or chemicals such as formaldehyde 3. ... A seasonally-specific component of the influenza vaccine. ... The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from …
Displaying drugs 476 - 500 of 12915 in total