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Displaying drugs 526 - 550 of 1258 in total
Celiprolol is indicated for the management of mild to moderate hypertension and effort-induced angina pectoris. It is simultaneously a selective β1 receptor antagonist, a β2 receptor partial agonist and a weak α2 receptor antagonist. In 2010 a clinical trial has suggested a use for this medication in the prevention of...
Approved
Investigational
Matched Synonyms: … RS)-N'-{3-acetyl-4-[3-(tert-butylamino)-2-hydroxypropoxy]phenyl}-N,N-diethylurea …
Matched Iupac: … 1-{3-acetyl-4-[3-(tert-butylamino)-2-hydroxypropoxy]phenyl}-3,3-diethylurea …
Matched Description: … Celiprolol is indicated for the management of mild to moderate hypertension and effort-induced angina ... It is simultaneously a selective β1 receptor antagonist, a β2 receptor partial agonist and a weak α2 …
Experimental
Matched Synonyms: … 3-phenyl-2-oxopropanoate ... 3-phenyl-2-oxopropanoic acid …
Sudapyridine is under investigation in clinical trial NCT05824871 (Sudapyridine (WX-081) in Rr/mdr/xdr-tuberculosis Patients).
Investigational
Matched Synonyms: … 3-Pyridineethanol, 5-(4-chlorophenyl)-α-[2-(dimethylamino)ethyl]-2-methoxy-α-1-naphthalenyl-β-phenyl- ... αS,βR)-5-(4-Chlorophenyl)-α-[2-(dimethylamino)ethyl]-2-methoxy-α-1-naphthalenyl-β-phenyl-3-pyridineethanol …
Fenofibrate is a fibric acid derivative like clofibrate and gemfibrozil. Fenofibrate is used to treat primary hypercholesterolemia, mixed dyslipidemia, severe hypertriglyceridemia.[L8588,L8591] Fenofibrate was granted FDA approval on 31 December 1993.
Approved
Matched Synonyms: … Isopropyl 2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropionate ... Isopropyl (4'-(p-chlorobenzoyl)-2-phenoxy-2-methyl)propionate ... 2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic acid 1-methylethyl ester …
Matched Iupac: … propan-2-yl 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate …
Matched Description: … Fenofibrate is a fibric acid derivative like [clofibrate] and [gemfibrozil]. …
Matched Categories: … Phenols ... Phenyl Ethers ... pravastatin and fenofibrate ... simvastatin and fenofibrate ... rosuvastatin and fenofibrate …
Ethotoin is a hydantoin derivative and anticonvulsant. Ethotoin exerts an antiepileptic effect without causing general central nervous system depression. The mechanism of action is probably very similar to that of phenytoin. The latter drug appears to stabilize rather than to raise the normal seizure threshold, and to prevent the spread...
Approved
Matched Synonyms: … 3-ethyl-5-phenyl-2,4-imidazolidinedione ... 3-Ethyl-5-phenyl-imidazolidine-2,4-dione …
Matched Description: … Ethotoin is a hydantoin derivative and anticonvulsant. ... The latter drug appears to stabilize rather than to raise the normal seizure threshold, and to prevent …
Olopatadine is a selective histamine H1 antagonist and mast cell stabilizer that works by attenuating inflammatory and allergic reactions. It is a structural analog of doxepin, which has a minimal anti-allergic activity. Olopatadine works by blocking the effects of histamine, which is a primary inflammatory mediator that causes inflammatory and...
Approved
Matched Description: … seasonal and perennial allergic conjunctivitis in 1996 and 2002, respectively. ... inflammatory and allergic reactions. ... Olopatadine is a selective histamine H1 antagonist and mast cell stabilizer that works by attenuating …
Matched Categories: … Decongestants and Antiallergics …
Matched Products: … Eye Allergy Itch and Redness Relief ... Eye Allergy Itch and Redness Relief Twice Daily Relief …
Phenazopyridine, also known as Pyridium, is a urinary tract analgesic used for the short-term management of urinary tract irritation and its associated unpleasant symptoms such as burning and pain during urination. In the USA, this drug was previously marked by Roche but has been discontinued by the FDA. It is...
Approved
Matched Description: … its associated unpleasant symptoms such as burning and pain during urination. ... Pyridium, is a urinary tract analgesic used for the short-term management of urinary tract irritation and
Matched Mixtures name: … Phenazopyridine Hydrochloride, Hyoscyamine Hydrobromide, and Butabarbital …
Matched Categories: … Antipruritics and Local Anesthetics ... Genito Urinary System and Sex Hormones …
Matched Products: … Foster and Thrive Maximum Strength Urinary Pain Relief ... Foster and Thrive Neighbor Pharmacy Urinary Pain Relief …
Investigational
Matched Synonyms: … 2,4(1h,3h)-quinazolinedione, 5-fluoro-1-((4-fluoro-3-((4-(2-pyrimidinyl)-1-piperazinyl)carbonyl)phenyl ... 5-fluoro-1-((4-fluoro-3-((4-(2-pyrimidinyl)-1-piperazinyl)carbonyl)phenyl)methyl)-2,4(1h,3h)-quinazolinedione …
Matched Iupac: … 5-fluoro-1-({4-fluoro-3-[4-(pyrimidin-2-yl)piperazine-1-carbonyl]phenyl}methyl)-1,2,3,4-tetrahydroquinazoline …
Ranitidine is a commonly used drug, classified as a histamine H2-receptor antagonist, and belongs to the same drug class as cimetidine and famotidine. This drug helps to prevent and treat gastric-acid associated conditions, including ulcers, because of its ability to decrease gastric acid secretion.[A176759,L10818] Ranitidine is often referred to as...
Approved
Withdrawn
Matched Description: … the same drug class as [cimetidine] and [famotidine]. ... tablet, injection, and effervescent tablet preparations. ... is therefore widely used in GERD and other gastric-acid related conditions. …
Matched Categories: … Alimentary Tract and Metabolism ... Drugs for Peptic Ulcer and Gastro-Oesophageal Reflux Disease (Gord) …
Matched Products: … Up and Up Ranitidine ... Up and Up Ranitidine 150 ... Berkley and Jensen Ranitidine …
Experimental
Matched Synonyms: … N-[(3S)-1-hydroxy-2-oxo-5-phenyl-3-pentanyl]-Nα-[(3-pyridinylmethoxy)carbonyl]-L-phenylalaninamide …
Matched Name: … [1-(3-hydroxy-2-oxo-1-phenethyl-propylcarbamoyl)2-phenyl-ethyl]-carbamic acid pyridin-4-ylmethyl ester …
Telapristone acetate, an orally-available, selective progesterone receptor modulator, is in development to alleviate symptoms associated with both uterine fibroids and endometriosis.
Investigational
Matched Synonyms: … 17alpha-Acetoxy-11beta-(4-(dimethylamino)phenyl)-21-methoxy-19-norpregna-4,9-dien-3,20-dione …
Matched Iupac: … (1R,3aS,3bS,10R,11aS)-10-[4-(dimethylamino)phenyl]-1-(2-methoxyacetyl)-11a-methyl-7-oxo-1H,2H,3H,3aH, …
Matched Description: … progesterone receptor modulator, is in development to alleviate symptoms associated with both uterine fibroids and
Levocetirizine is a selective histamine H1 antagonist used to treat a variety of allergic symptoms.[A181748,A181790,L7694] It is the R enantiomer of cetirizine. Levocetirizine has greater affinity for the histamine H1 receptor than cetirizine. Levocetirizine was granted FDA approval in 1995.
Approved
Matched Synonyms: … 2-(2-{4-[(R)-(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid …
Matched Iupac: … 2-(2-{4-[(R)-(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid …
Matched Categories: … Cetirizine and isomer …
Motolimod has been used in trials studying the treatment of Lymphoma, Tongue Cancer, Ovarian Cancer, Adult Solid Neoplasm, and Fallopian Tube Cancer, among others.
Investigational
Matched Synonyms: … {2-amino-8-[4-(pyrrolidinylcarbonyl)phenyl](3H-benzo[f]azepin-4-yl)}-N,N-dipropycarboxamide …
Matched Iupac: … 2-amino-N,N-dipropyl-8-[4-(pyrrolidine-1-carbonyl)phenyl]-3H-1-benzazepine-4-carboxamide …
Matched Description: … in trials studying the treatment of Lymphoma, Tongue Cancer, Ovarian Cancer, Adult Solid Neoplasm, and
Investigational
Matched Synonyms: … N-((3-bromo-4-(3-(fluoro-18f)propoxy)phenyl)methyl)guanidine …
Matched Iupac: … N-({3-bromo-4-[3-(¹⁸F)fluoropropoxy]phenyl}methyl)guanidine …
N-hydroxy-4-({4-[4-(trifluoromethyl)phenoxy]phenyl}sulfonyl)tetrahydro-2H-pyran-4-carboxamide is a solid. This compound belongs to the diarylethers. These are organic compounds containing the dialkyl ether functional group, with the formula ROR', where R and R' are aryl groups. This substance is known to target a disintegrin and metalloproteinase with thrombospondin motifs 5.
Experimental
Matched Name: … N-hydroxy-4-({4-[4-(trifluoromethyl)phenoxy]phenyl}sulfonyl)tetrahydro-2H-pyran-4-carboxamide …
Matched Iupac: … N-hydroxy-4-{4-[4-(trifluoromethyl)phenoxy]benzenesulfonyl}oxane-4-carboxamide …
Matched Description: … N-hydroxy-4-({4-[4-(trifluoromethyl)phenoxy]phenyl}sulfonyl)tetrahydro-2H-pyran-4-carboxamide is a solid ... This substance is known to target a disintegrin and metalloproteinase with thrombospondin motifs 5. ... are organic compounds containing the dialkyl ether functional group, with the formula ROR', where R and
A cardioselective beta-1-adrenergic antagonist with no partial agonist activity.
Approved
Investigational
Matched Synonyms: … 1-(isopropylamino)-3-[p-(cyclopropylmethoxyethyl)phenoxy]-2-propanol ... 1-(4-(2-(cyclopropylmethoxy)ethyl)phenoxy)-3-((1-methylethyl)amino)-2-propanol …
Matched Iupac: … 1-{4-[2-(cyclopropylmethoxy)ethyl]phenoxy}-3-[(propan-2-yl)amino]propan-2-ol …
Matched Categories: … Antiglaucoma Preparations and Miotics …
Cardamonin (also known as Dihydroxymethoxychalcone), as shown by the increasing number of publications, has received growing attention from the scientific community due to the expectations toward its benefits to human health. Cardamonin's name comes from the fact that it can be found in cardamom spice.
Experimental
Matched Synonyms: … (E)-1-(2,4-Dihydroxy-6-methoxyphenyl)-3-phenyl-2-propen-1-one …
Investigational
Matched Synonyms: … 2-tert-butyl-4-chloro-5-((4-((2-(18f)fluoroethoxy)methyl)phenyl)methoxy)pyridazin-3(2h)-one ... 3(2h)-pyridazinone, 4-chloro-2-(1,1-dimethylethyl)-5-((4-((2-(fluoro-18f)ethoxy)methyl)phenyl)methoxy ... 4-chloro-2-(1,1-dimethylethyl)-5-((4-((2-((sup 18)f)fluoroethoxy)methyl)phenyl) methoxy)pyridazin-3(2h …
Investigational
Matched Synonyms: … (+)-(2s)-2-(4-chloro-2-methoxyphenyl)-2-((3-methoxy-5-(methylsulfonyl)phenyl)amino)-1-(5-(trifluoromethoxy ... 2-(4-chloro-2-methoxyphenyl)-2-((3-methoxy-5-(methylsulfonyl)phenyl)amino)-1-(5-(trifluoromethoxy)-1h-indol ... Ethanone, 2-(4-chloro-2-methoxyphenyl)-2-((3-methoxy-5-(methylsulfonyl)phenyl)amino)-1-(5-(trifluoromethoxy …
Niacin is a B vitamin used to treat vitamin deficiencies as well as hyperlipidemia, dyslipidemia, hypertriglyceridemia, and to reduce the risk of myocardial infarctions.[L7550,L7553,L7556,L7559,L7562,L7565]
Approved
Investigational
Nutraceutical
Matched Description: … vitamin used to treat vitamin deficiencies as well as hyperlipidemia, dyslipidemia, hypertriglyceridemia, and
Matched Mixtures name: … Niacin 500 Mg and Inositol ... Multi-Vitamin Fluoride and Iron Drops ... Revit Multi-vitamins and Minerals …
Matched Categories: … Diet, Food, and Nutrition ... Nicotinic Acid and Derivatives ... lovastatin and nicotinic acid …
Matched Products: … JEUNCELL Hair restorer and Hair Growth Solution …
Panthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an essential component of a normally functioning epithelium. Panthenol exists as a racemic mixture containing both the dextrorotatory form (dexpanthenol) and the levorotatory form (levopanthenol). While pantothenic acid is optically active, only the dextrorotatory...
Approved
Matched Description: … Panthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an ... Panthenol exists as a racemic mixture containing both the dextrorotatory form (dexpanthenol) and the ... Due to its good penetration and high local concentrations, dexpanthanol is used in many topical products …
Matched Mixtures name: … Therapytion Nokmosu Neutral and oily Hair ... Therapytion Nokmosu Sensitive and Dry Hair …
Matched Categories: … Amino Acids, Peptides, and Proteins …
Matched Products: … BABOR Baborganic Calm and Relax …
Experimental
Matched Name: … 5-[(2-methyl-5-{[3-(trifluoromethyl)phenyl]carbamoyl}phenyl)amino]pyridine-3-carboxamide …
Matched Iupac: … 5-[(2-methyl-5-{[3-(trifluoromethyl)phenyl]carbamoyl}phenyl)amino]pyridine-3-carboxamide …
The (R)-enantiomer of rolipram, it is a phosphodiesterase inhibitor with antidepressant properties.
Experimental
Matched Synonyms: … (R)-4-(3-Cyclopentyloxy-4-methoxy-phenyl)-pyrrolidin-2-one …
Levomilnacipran is a selective serotonin and norepinephrine reuptake inhibitor (SNRI), although it is a more potent inhibitor of norepinephrine reuptake than serotonin reuptake.[A261181, A38560] Levomilnacipran is the more active 1S,2R-enantiomer in the racemate milnacipran.[A261181, L47956] Once administered, interconversion between levomilnacipran and its stereoisomer does not occur in humans. First approved...
Approved
Investigational
Matched Synonyms: … CYCLOPROPANECARBOXAMIDE, 2-(AMINOMETHYL)-N,N-DIETHYL-1-PHENYL-, (1S,2R)- …
Matched Description: … Levomilnacipran is a selective serotonin and norepinephrine reuptake inhibitor (SNRI), although it is ... [A261181, L47956] Once administered, interconversion between levomilnacipran and its stereoisomer does ... [L47956] While levomilnacipran was previously investigated and proposed as a potential treatment for …
Matched Categories: … Milnacipran and enantiomer ... Serotonin and Noradrenaline Reuptake Inhibitors …
Pittsburgh Compound B is under investigation in clinical trial NCT01723553 (Amyloid-related Imaging Abnormalities (Microbleeds) in Atypical AD).
Investigational
Matched Synonyms: … 2-(4'-(methylamino)phenyl)-6-hydroxybenzothiazole …
Matched Iupac: … 2-{4-[(11C)methylamino]phenyl}-1,3-benzothiazol-6-ol …
Displaying drugs 526 - 550 of 1258 in total