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Displaying drugs 551 - 575 of 2819 in total
A pyrazine compound inhibiting sodium reabsorption through sodium channels in renal epithelial cells. This inhibition creates a negative potential in the luminal membranes of principal cells, located in the distal convoluted tubule and collecting duct. Negative potential reduces secretion of potassium and hydrogen ions. Amiloride is used in conjunction with...
Approved
Matched Description: … Negative potential reduces secretion of potassium and hydrogen ions. ... negative potential in the luminal membranes of principal cells, located in the distal convoluted tubule and ... (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p705) …
Matched Mixtures name: … Amiloride Hydrochloride and Hydrochlorothiazide ... Amiloride Hydrochloride and Hydrochlorothiazide ... Amiloride Hydrochloride and Hydrochlorothiazide …
Matched Salts name: … Amiloride hydrochloride ... Amiloride hydrochloride dihydrate …
Matched Categories: … Acid Sensing Ion Channel Blockers …
Matched Products: … Amiloride Hydrochloride ... Amiloride Hydrocloride ... Amiloride Hydrochloride Tablets, USP …
Magaldrate is an antacid drug used for the treatment of esophagitis, duodenal and gastric ulcers, and gastroesophageal reflux. Magaldrate has been discontinued in the US market.
Approved
Withdrawn
Matched Synonyms: … Magnesium aluminate hydrate ... Aluminium magnesium hydroxide sulfate hydrate ... Aluminum magnesium hydroxide sulfate hydrate …
Matched Description: … Magaldrate is an antacid drug used for the treatment of esophagitis, duodenal and gastric ulcers, and
Matched Categories: … Aluminum and magnesium containing antacids ... Alimentary Tract and Metabolism ... magaldrate and antiflatulents ... Magnesium Compounds ... Gastric Acid Lowering Agents …
Trimethobenzamide is a novel antiemetic which prevents nausea and vomiting in humans. Its actions are unclear but most likely involves the chemoreceptor trigger zone (CTZ). In dogs pretreated with trimethobenzamide HCl, the emetic response to apomorphine is inhibited, while little or no protection is afforded against emesis induced by intragastric...
Approved
Investigational
Matched Description: … Trimethobenzamide is a novel antiemetic which prevents nausea and vomiting in humans. …
Matched Salts name: … Trimethobenzamide hydrochloride
Matched Categories: … Acids, Carbocyclic ... Carboxylic Acids
Matched Products: … Trimethobenzamide Hydrochloride ... Trimethobenzamide hydrochloride ... Trimethobenzamide Hydorchloride
Norgestimate was first described in the literature in 1977. It was developed by Ortho Pharmaceutical Corporation as part of an effort to develop new hormonal contraceptives with reduced adverse effects. It is commonly formulated with ethinylestradiol as a combined oral contraceptive that can also be used to treat moderate acne...
Approved
Investigational
Matched Synonyms: … d-13β-Ethyl-17α-ethynyl-17β-acetoxygon-4-en-3-one oxime ... (17α)-17-(Acetyloxy)-13-ethyl-18,19-dinorpregn-4-en-20-yn-3-one 3-oxime ... (+)-13-Ethyl-17-hydroxy-18,19-dinor-17α-pregn-4-en-20-yn-3-one oxime acetate (ester) …
Matched Mixtures name: … Norgestimate and Ethinyl Estradiol ... Norgestimate and Ethinyl Estradiol ... Norgestimate and Ethinyl Estradiol …
Matched Categories: … Combination Contraceptives (with Estrogen and derivatives) ... norgestimate and estrogen ... Genito Urinary System and Sex Hormones ... norgestimate and ethinylestradiol ... norgestimate and ethinylestradiol …
Docetaxel is a clinically well established anti-mitotic chemotherapy medication used for the treatment of different types of cancer, including breast, ovarian, and non-small cell lung cancer. Docetaxel is a complex diterpenoid molecule and a semisynthetic analogue of paclitaxel.[A259676,L46466] Docetaxel reversibly binds to microtubulin with high affinity in a 1:1 stoichiometric...
Approved
Investigational
Matched Description: … chemotherapy medication used for the treatment of different types of cancer, including breast, ovarian, and ... Docetaxel is a complex diterpenoid molecule and a semisynthetic analogue of [paclitaxel]. ... microtubulin with high affinity in a 1:1 stoichiometric ratio, allowing it to prevent cell division and
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Matched Products: … Oncotaxel Concentrate and solvent for solution for infusion 40 mg/ ml …
Calcium threonate is a calcium salt of threnoic acid and a novel drug developed for the treatment of osteoporosis and as a calcium supplement . It is found in dietary supplements as a source of L-threonate used in the treatment of calcium deficiency and prevention of osteoporosis. The most common...
Approved
Matched Synonyms: … Calcium L-threonate ... Threonine, calcium salt …
Matched Name: … Calcium threonate …
Matched Iupac: … calcium bis((2R,3S)-2,3,4-trihydroxybutanoate) …
Matched Description: … Calcium threonate is a calcium salt of threnoic acid and a novel drug developed for the treatment of ... osteoporosis and as a calcium supplement [A27266]. ... Therapeutic efficacy of calcium threonate in reducing was studied and investigated due to the hypothesis …
Matched Mixtures name: … Iron Fumarate and Aspartate, Glycinate, Ascorbic Calcium, Vitamin B12, Folic Acid, Calcium Threonate ... Iron Aspartate Glycinate and Polysaccharide Complex, Ascorbic Calcium, Vitamin B12, Folic Acid, Calcium ... Iron Aspartate, Glycinate, Ascorbic Calcium, Vitamin B12, Calcium Threonate and Succinic Acid
Matched Categories: … Fatty Acids ... Acids, Acyclic ... Carboxylic Acids ... Fatty Acids, Volatile …
Investigational
Matched Synonyms: … Androstan-17-one, 3-ethynyl-3-hydroxy-, oxime, (3.beta.,5.alpha.,17e)- …
Experimental
Matched Name: … 2-Nonyl-4-quinolinol 1-oxide
Ifosfamide is a chemotherapeutic agent chemically related to the nitrogen mustards and a synthetic analog of cyclophosphamide. It is active as an alkylating agent and an immunosuppressive agent.
Approved
Matched Synonyms: … 3-(2-chloroethyl)-2-((2-chloroethyl)amino)tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide
Matched Description: … It is active as an alkylating agent and an immunosuppressive agent. ... Ifosfamide is a chemotherapeutic agent chemically related to the nitrogen mustards and a synthetic analog …
Matched Mixtures name: … IFEX and MESNEX ... IFEX and MESNEX ... IFEX and MESNEX …
Matched Categories: … Antineoplastic and Immunomodulating Agents …
Roxithromycin is a semi-synthethic macrolide antibiotic that is structurally and pharmacologically similar to erythromycin, azithromycin, or clarithromycin. It was shown to be more effective against certain Gram-negative bacteria, particularly Legionella pneumophila. Roxithromycin exerts its antibacterial action by binding to the bacterial ribosome and interfering with bacterial protein synthesis. It is...
Approved
Investigational
Withdrawn
Matched Synonyms: … (9E)-erythromycin 9-(O-((2-methoxyethoxy)methyl)oxime) …
Matched Description: … Roxithromycin is a semi-synthethic macrolide antibiotic that is structurally and pharmacologically similar ... Roxithromycin exerts its antibacterial action by binding to the bacterial ribosome and interfering with ... It is marketed in Australia as a treatment for respiratory tract, urinary and soft tissue infections. …
Matched Categories: … Erythromycin and similars ... Macrolides, Lincosamides and Streptogramins …
Nutraceutical
Matched Synonyms: … Magnesium diasporal …
Matched Name: … Magnesium levulinate …
Matched Iupac: … magnesium(2+) bis(4-oxopentanoate) …
Matched Categories: … Alimentary Tract and Metabolism ... Keto Acids ... Carboxylic Acids ... Magnesium Compounds ... magnesium levulinate …
Matched Products: … MAGNESIUM DIASPORAL 300MG …
A uricosuric drug that is used to reduce the serum urate levels in gout therapy. It lacks anti-inflammatory, analgesic, and diuretic properties.
Approved
Matched Description: … It lacks anti-inflammatory, analgesic, and diuretic properties. …
Matched Categories: … Preparations Increasing Uric Acid Excretion …
Matched Products: … Antazone Tab 100mg ... Antazone Tab 200mg …
Experimental
Matched Synonyms: … Zinc diiodide …
Matched Name: … Zinc iodide …
Experimental
Matched Synonyms: … Calcium sulphate ... Calcium sulfate, anhydrous …
Matched Name: … Calcium sulfate …
Matched Iupac: … calcium sulfate …
Matched Categories: … Calcium Compounds ... Sulfur Acids ... Sulfuric Acids
Azoximer bromide is under investigation in clinical trial NCT04381377 (Efficacy and Safety of Polyoxidonium® in Hospitalized Patients With Coronavirus Disease COVID-19).
Investigational
Matched Synonyms: … Poly((1-(carboxymethyl)piperazin-1-ium-1,4-diyl bromide)ethylene-co-((piperazin-1,4-diyl 1-oxide)ethylene …
Matched Description: … Azoximer bromide is under investigation in clinical trial NCT04381377 (Efficacy and Safety of Polyoxidonium …
Experimental
Matched Name: … Xylose-derived lactam oxime
Eldecalcitol (ED-71), a vitamin D analog, is a more potent inhibitor of bone resorption than alfacalcidol in an estrogen-deficient rat model of osteoporosis. Eldecalcitol, effectively and safely increased lumbar and hip bone mineral density (BMD) in osteoporotic patients who also received vitamin D3 supplementation.
Investigational
Matched Synonyms: … 1α,25-dihydroxy-2β-(3-hydroxypropoxy)cholecalciferol
Matched Description: … Eldecalcitol, effectively and safely increased lumbar and hip bone mineral density (BMD) in osteoporotic …
Matched Categories: … Vitamin D and Analogues …
Approved
Experimental
Matched Synonyms: … Magnesium aluminometasilicate …
Experimental
Matched Synonyms: … Zinc protoporphyrin-9 ... Zinc-protoporphyrin IX …
Matched Name: … Zinc protoporphyrin …
Matched Iupac: … zinc(2+) 4,20-bis(2-carboxyethyl)-9,14-diethenyl-5,10,15,19-tetramethyl-21,22,23,24-tetraazapentacyclo …
Experimental
Matched Synonyms: … Calcium sulphide …
Matched Name: … Calcium sulfide …
Matched Iupac: … calcium sulfanediide …
An anti-inflammatory analgesic and antipyretic highly bound to plasma proteins. It is pharmacologically similar to aspirin, but causes less gastrointestinal bleeding.
Approved
Matched Synonyms: … 3-phenoxyhydratropic acid ... (+/-)-m-phenoxyhydratropic acid ... 2-(3-phenoxyphenyl)propionic acid
Matched Iupac: … 2-(3-phenoxyphenyl)propanoic acid
Matched Description: … An anti-inflammatory analgesic and antipyretic highly bound to plasma proteins. …
Matched Salts name: … Fenoprofen calcium
Matched Categories: … Antiinflammatory and Antirheumatic Products ... Antiinflammatory and Antirheumatic Products, Non-Steroids ... Acids, Carbocyclic ... Carboxylic Acids ... Arylpropionic acid NSAIDS …
Matched Products: … Fenoprofen Calcium
Alendronic acid is a second generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111]. It functions by preventing resorption of bone[FDA Label] .
Approved
Matched Synonyms: … Alendronic acid ... Acido Alendronico ... Acide Alendronique …
Matched Name: … Alendronic acid
Matched Iupac: … (4-amino-1-hydroxy-1-phosphonobutyl)phosphonic acid
Matched Description: … osteoperosis and Paget's disease[FDA Label][A959,A203111]. ... Alendronic acid is a second generation bisphosphonate that is used for the treatment of some forms of …
Matched Mixtures name: … Alendronate-cholecalciferol ... Alendronate-cholecalciferol ... Teva-alendronate/cholecalciferol
Matched Salts name: … Alendronate calcium
Matched Categories: … alendronic acid, calcium and colecalciferol, sequential ... alendronic acid and colecalciferol ... alendronic acid and alfacalcidol, sequential ... Drugs Affecting Bone Structure and Mineralization ... alendronic acid
Matched Products: … ACIDO ALENDRONICO FIDIA ... ALENDRONAT ACIS 70MG ... ACIDO ALENDRONICO FG …
Experimental
Matched Name: … Ferricrocin-iron
Matched Iupac: … oxidaniumylideneethyl)amino]propyl})-15-(hydroxymethyl)-1,4,7,10,13,16-hexaazacyclooctadecane-2,5,8,11,14,17-hexone iron
Hyaluronic acid (HA) is an anionic, nonsulfated glycosaminoglycan found in connective, epithelial, and neural tissues; it was first isolated in 1934. Karl Meyer and John Palmer obtained glycosaminoglycan (GAG) from the bovine eye, giving it the name “hyaluronic acid”. HA is involved in many important physiological processes, including but not...
Approved
Vet approved
Matched Name: … Hyaluronic acid
Matched Iupac: … 3R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy}-4,5-dihydroxyoxane-2-carboxylic acid
Matched Description: … Hyaluronic acid (HA) is an anionic, nonsulfated glycosaminoglycan found in connective, epithelial, and ... [A230133] Several preparations of hyaluronic acid have been approved by the FDA and are available in ... hyaluronic acid”. …
Matched Mixtures name: … Hyaluronic Acid 60mg and Lidocaine 2% PF ... ELDEEN AGE TWENTY ONE MifitPatch and Serum ... ELDEEN AGE TWENTY ONE MifitPatch and Serum …
Matched Categories: … Preparations for Treatment of Wounds and Ulcers ... hyaluronic acid ... hyaluronic acid ... hyaluronic acid ... hyaluronic acid
Matched Products: … Hyaluronic Acid Micro ... Hyaluronic Acid ... Hyaluronic Acid Gel …
Meclizine is a histamine H1 antagonist with antiemetic and antivertigo properties. It is used in the symptomatic treatment of motion sickness and control of vertigo associated with vestibular system diseases. It also exhibits anticholinergic, central nervous system depressant, and local anesthetic effects. Commonly marketed under the brand name Antivert in...
Approved
Matched Description: … Meclizine is a histamine H1 antagonist with antiemetic and antivertigo properties. ... It is used in the symptomatic treatment of motion sickness and control of vertigo associated with vestibular ... It also exhibits anticholinergic, central nervous system depressant, and local anesthetic effects. …
Matched Salts name: … Meclizine hydrochloride
Matched Products: … Meclizine Hydrochloride ... Meclizine Hydrocloride ... Meclizine hydrochloride
Displaying drugs 551 - 575 of 2819 in total