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Displaying drugs 601 - 625 of 3434 in total

Linaclotide

Linaclotide is a synthetic 14-amino acid cyclic peptide and first-in-class guanylate cyclase-C (G-CC) agonist.[A260271, L47211] Linaclotide is structurally related to human guanylin and uroguanylin, paracrine peptide hormones that are endogenous activators of GC-C. It is also a homolog of a heat-stable enterotoxin derived from Escherichia coli, the first natural ligand...
Approved
Matched Synonyms: … GLUTAMYL-L-TYROSYL-L-CYSTEINYL-L-CYSTEINYL-L-ASPARAGINYL-L-PROLYL-L-ALANYL-L-CYSTEINYL-L-THREONYLGLYCYL-L-CYSTEINYL-, CYCLIC (1->6),(2->10 …
Matched Iupac: … -18,19,35,36,48,49-hexathia-2,5,11,14,23,26,29,32,39,42,45,52-dodecaazatetracyclo[22.22.4.2^{16,33}.0^ …

Plasma protein fraction (human)

The plasma protein fraction human (PPFh) is defined as a sterile solution of proteins composed mainly of albumin and globulin derived from human plasma. It is already reviewed under the category of biologics by the FDA where the processing, required tests, requirements and labeling are incorporated. This biologic should come...
Approved
Matched Products: … Octaplas SD Blutgruppe 0 zur Infusion …

Lanolin

Lanolin is a yellow fat obtained from sheep's wool. It is used as an emollient, cosmetic, and pharmaceutic aid . The US federal code of regulations states that lanolin in the concentration range of 12-50% may be included in over the counter skin ointments . Lanolin is the purified, secreted...
Approved
Matched Products: … Smartchoices Lanolin Plus 0 …

Bleomycin

A complex of related glycopeptide antibiotics from Streptomyces verticillus consisting of bleomycin A2 and B2 (B2 CAS # 9060-10-0). It inhibits DNA metabolism and is used as an antineoplastic, especially for solid tumors. Bleomycin A2 is used as the representative structure for Bleomycin.
Approved
Investigational
Matched Description: … -0). ... glycopeptide antibiotics from Streptomyces verticillus consisting of bleomycin A2 and B2 (B2 CAS # 9060-10 …

Sodium bicarbonate

Sodium bicarbonate is a white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions.
Approved
Matched Mixtures name: … Prismasol 0 ... Prismasol Bgk2/0 ... Phoxillum B22k4/0 …
Matched Products: … BICARBONATO DE SODIO 10 MEQ / 10 ML ... Sodium Bicarbonate 10 gr ... TÜRKTIPSAN MOLAR SODYUM 840 MG/10 ML IV ENJEKSİYONLUK ÇÖZELTİ, 10 ADET …

Codeine

The relief of pain (analgesia) is a primary goal for enhancing the quality of life of patients and for increasing the ability of patients to engage in day to day activities. Codeine, an opioid analgesic, was originally approved in the US in 1950 and is a drug used to decrease...
Approved
Illicit
Matched Iupac: … (1S,5R,13R,14S,17R)-10-methoxy-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca …
Matched Mixtures name: … FENOKODIN 20 MG / 10 MG TABLET, 20 ADET ... A-FERİN 300 MG/2 MG/10 MG KAPSÜL, 20 ADET ... A-FERİN 300 MG/2 MG/10 MG KAPSÜL, 30 ADET …
Matched Products: … COLINCTUS 10 MIXTURE 10 mg/5 ml ... CODIKAF 10 ... COUGH LINCTUS 10 mg/5 ml …

Tadalafil

Tadalafil is a selective phosphodiesterase-5 inhibitor that is used in the treatment of erectile dysfunction (ED), pulmonary arterial hypertension (PAH), and benign prostatic hypertrophy.[L39100, L39105] It was first approved in 2003 by the FDA for use in ED and later in 2009 for PAH. In contrast to other PDE5 inhibitors...
Approved
Investigational
Matched Iupac: … -1(10),11,13,15-tetraene-4,7-dione ... (2R,8R)-2-(2H-1,3-benzodioxol-5-yl)-6-methyl-3,6,17-triazatetracyclo[8.7.0.0^{3,8}.0^{11,16}]heptadeca …
Matched Products: … TADAFIL 10 TADALAFIL TABLETS USP 10 MG ... PROMEL 10 ... ทาลาฟิล-10 …

Alprostadil

Alprostadil is a chemically-identical synthetic form of prostaglandin E1 (PGE1), a potent vasodilator produced endogenously. In 1996, the FDA approved the use of alprostadil, administered either with an intracavernosal injection or an intraurethral suppository, for the treatment of erectile dysfunction, and it is used in men for whom oral treatment...
Approved
Investigational
Matched Products: … CAVERJECT POWDER FOR INJECTION 10 mcg/ml ... Caverject Dual 10 µg - Zweikammerzylinderampullen ... Caverject 10 µg - Trockenstechampulle mit Lösungsmittelspritze …

Metoprolol

Metoprolol is a selective beta-1 blocker commonly employed as the succinate and tartrate derivatives depending if the formulation is designed to be of immediate release or extended release.[A175159, L5530] The possibility of the generation of these formulations comes from the lower systemic bioavailability of the succinate derivative. To this date,...
Approved
Investigational
Matched Salts cas: … 119637-66-0 …
Matched Products: … ENJEKSIYONLUK ÇÖZELTI IÇEREN AMPUL ,10 AMPUL ... METOPROLOL ABZ 0.K. 50MG ... METOPROLOL ABZ 0.K. 100MG …

Tofersen

Tofersen is under an intrathecally administered antisense oligonucleotide targeting the mutated SOD1 gene that causes amyotrophic lateral sclerosis (ALS). Although there were various causes of ALS, 2% of ALS cases are due to SOD1 mutations, with more than 200 SOD1 mutations documented.[A259028,A259033] Tofersen was granted accelerated approval from the FDA...
Approved
Investigational

Orciprenaline

A beta-adrenergic agonist used in the treatment of asthma and bronchospasms. [PubChem]
Approved

Fluticasone furoate

Fluticasone furoate is a synthetic glucocorticoid available as an inhaler and nasal spray for various inflammatory indications[FDA Label] . Fluticasone furoate was first approved in 2007 .
Approved
Matched Iupac: … (1R,2R,3aS,3bS,5S,9aS,9bR,10S,11aS)-5,9b-difluoro-1-{[(fluoromethyl)sulfanyl]carbonyl}-10-hydroxy-2,9a …

Sulfacetamide

An anti-infective agent that is used topically to treat skin infections and orally for urinary tract infections.
Approved
Matched International brands: … Blef-10 …
Matched Mixtures name: … Se 10-5 Ss ... Sulfatol 10-4 Cleansing pads ... Sodium Sulfacetamide 10 Sulfur 5 …
Matched Products: … Sulf 10 ... Re 10 Wash ... Bleph-10 …

Lindane

An organochlorine insecticide that has been used as a pediculicide and a scabicide. Lindane has been banned in California, United Kingdom, Australia, and many western countries due to concerns about neurotoxicity and adverse effects on the environment. In Canada, Lindane is not recommmended as a first-line therapy due to reports...
Approved
Withdrawn

Amlodipine

Amlodipine, initially approved by the FDA in 1987, is a popular antihypertensive drug belonging to the group of drugs called dihydropyridine calcium channel blockers. Due to their selectivity for the peripheral blood vessels, dihydropyridine calcium channel blockers are associated with a lower incidence of myocardial depression and cardiac conduction abnormalities...
Approved
Matched International brands: … Amlodipin-Mepha 5/10 …
Matched Salts cas: … 1239916-29-0 ... 246852-12-0 …
Matched Mixtures name: … ./10 มก./10 มก. ... COVERAM 10 MG/10 MG ... RAMI/AMLODIPIN RATIO 10/10 …
Matched Products: … AMCAD 10 TABLET 10 MG ... AMLONG-10 TABLET 10 mg ... AMTAS-10 TABLET 10 mg …

Rivaroxaban

Rivaroxaban is an anticoagulant and the first orally active direct factor Xa inhibitor. Unlike warfarin, routine lab monitoring of INR is not necessary. However there is no antidote available in the event of a major bleed. Only the 10 mg tablet can be taken without regard to food. The 15...
Approved
Matched Description: … Only the 10 mg tablet can be taken without regard to food. …
Matched Products: … VENOMİA 10 MG SERT KAPSÜL, 10 ADET ... ONAXAN 10 MG FİLM KAPLI TABLET, 10 TABLET ... NOSTROK 10 …

Isotretinoin

Isotretinoin is a retinoid derivative of vitamin A used in the treatment of severe recalcitrant acne.[Label] It was most widely marketed under the brand name Accutane, which has since been discontinued. Isotretinoin is associated with major risks in pregnancy and is therefore only available under the iPLEDGE program in the...
Approved
Matched Products: … TINOIN-10 ... ซอฟเทน 10 ... ISONIN 10 …

Dihydroergotamine

A 9,10alpha-dihydro derivative of ergotamine. Dihydroergotamine is used as an abortive therapy for migraines. Its use has largely been supplanted by triptans in current therapy due to the class's greater selectivity and more favourable side effect profile. Recent improvements have been made in the design of intranasal delivery devices allowing...
Approved
Investigational
Matched Iupac: … dioxo-3-oxa-6,9-diazatricyclo[7.3.0.0^{2,6}]dodecan-4-yl]-6-methyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^ …

Astemizole

Astemizole is a long-acting, non-sedating second generation antihistamine used in the treatment of allergy symptoms. It was withdrawn from market by the manufacturer in 1999 due to the potential to cause arrhythmias at high doses, especially when when taken with CYP inhibitors or grapefruit juice.
Approved
Withdrawn
Matched Products: … ALMIZOL 10 MG TABLET, 10 ADET ... ULKAMIZOL 10 MG TABLET, 10 ADET ... ASTEMIZOL 10 MG TABLETAS …

Donepezil

In 2016, the global burden of dementia was estimated to be 43.8 million, demonstrating a significant increase from a global prevalence of 20.2 million in 1990. Donepezil, also known as Aricept, is a piperidine derivative acetylcholinesterase inhibitor used in the management of the dementia of Alzheimer's Disease, and in some...
Approved
Matched Mixtures name: … PHOCUSS 10/5+10/10+10/15+10/20 MG FILM KAPLI TABLET TEDAVIYE BAŞLAMA PAKETI, 28 ADET ... PHOCUSS 10/5+10/10+10/15+10/20 MG FILM KAPLI TABLET TEDAVIYE BAŞLAMA PAKETI, 28 ADET ... PHOCUSS 10/5+10/10+10/15+10/20 MG FILM KAPLI TABLET TEDAVIYE BAŞLAMA PAKETI, 28 ADET …
Matched Products: … Arimac 10 (Donepezil hydrochloride Tablets 10 mg) ... เอไมซ์ 10 ... แอลไซม์ 10 …

Baclofen

Baclofen is a gamma-aminobutyric acid (GABA) agonist used as a skeletal muscle relaxant. Although originally designed in 1962 to treat epilepsy, baclofen was not effective in treating this condition but instead was shown to reduce spasticity in selected patients. Baclofen was reintroduced in 1971 as a treatment for spasticity and...
Approved
Matched Products: … COLMIFEN 10 TABLET 10 mg ... LIORESAL 10 TABLET 10 mg ... Baclofen-10 …

Idarubicin

An orally administered anthracycline antineoplastic. The compound has shown activity against breast cancer, lymphomas and leukemias, together with the potential for reduced cardiac toxicity.
Approved
Matched Salts cas: … 57852-57-0 …
Matched Products: … ZAVEDOS CS INJECTION 10 mg/10 ml ... Idarubicin Accord 10 mg/10 ml Injektionslösung ... X 10 MG …

Propranolol

Propranolol is a racemic mixture of 2 enantiomers where the S(-)-enantiomer has approximately 100 times the binding affinity for beta adrenergic receptors. Propranolol is used to treat a number of conditions but most commonly is used for hypertension.[L6901,L6904,L6907] Propranolol was granted FDA approval on 13 November 1967.
Approved
Investigational
Matched Products: … EMFORAL 10 TABLET 10 mg ... LIBLOK 10 ... พาลอน 10 …

Tamoxifen

Tamoxifen is a non-steroidal antiestrogen used to treat estrogen receptor positive breast cancers as well as prevent the incidence of breast cancer in high risk populations.[A1025,L7799,L7802] Tamoxifen is used alone or as an adjuvant in these treatments.[L7799,L7802] Tamoxifen may no longer be the preferred treatment for these types of cancers...
Approved
Matched Products: … มาโมเฟน-10 (ทาม๊อกซิเฟน ชนิดเม็ด 10 มก.) ... Tamofen 10 ... NOVOFEN (10 MG) …

Solifenacin

Solifenacin is a competitive muscarinic receptor antagonist indicated to treat an overactive bladder with urinary incontinence, urgency, and frequency. It has a long duration of action as it is usually taken once daily. Solifenacin was granted FDA approval on 19 November 2004.
Approved
Matched Products: … ซอฟแคร์ 10 ... VESICARE 10 MG. ... CELEFEN® 10 MG …
Displaying drugs 601 - 625 of 3434 in total