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Displaying drugs 601 - 625 of 3163 in total
Originally developed in the 1950s as a malaria treatment, hydralazine showed antihypertensive ability and was soon repurposed. Hydralazine is a hydrazine derivative vasodilator used alone or as adjunct therapy in the treatment of hypertension and only as adjunct therapy in the treatment of heart failure.[A186820,L8782,L8785] Hydralazine is no longer a...
Approved
Matched Description: … Originally developed in the 1950s as a malaria treatment, hydralazine showed antihypertensive ability and ... hydrazine derivative vasodilator used alone or as adjunct therapy in the treatment of hypertension and ... [T691] Hydralazine hydrochloride was FDA approved on 15 January 1953.[L8779] …
Matched Mixtures name: … Isosorbide dinitrate and hydralazine hydrochloride ... Isosorbide Dinitrate and Hydralazine Hydrochloride ... Isosorbide Dinitrate and Hydralazine Hydrochloride
Matched Salts name: … Hydralazine hydrochloride
Matched Categories: … hydralazine and diuretics ... Hydrazinophthalazine Derivatives and Diuretics …
Matched Products: … Hydralazine Hydrochloride ... HydrALAZINE Hydrochloride ... Apresoline hydrochloride
Indopan (alpha-methyltryptamine) is a stimulant and psychoactive drug which produces effects similar to 3,4-methylenedioxy-N-methylamphetamine (MDMA), despite being structurally dissimilar. It was developed in the 1960's by Upjohn with the intention for use as an antidepressant. In the 1990's, indopan became regulated as a Schedule I controlled substance in the United...
Experimental
Illicit
Matched Synonyms: … DL-3-(2-Aminopropyl)indole ... alpha-methyltryptamine ... alpha-Methyl-1H-indole-3-ethanamine …
Matched Description: … Indopan (alpha-methyltryptamine) is a stimulant and psychoactive drug which produces effects similar …
Experimental
Matched Synonyms: … alpha-Aminoisobutyric acid ... alpha-Methylalanine ... 2-aminoisobutyric acid
Matched Name: … 2-aminoisobutyric acid
Matched Iupac: … 2-amino-2-methylpropanoic acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Acids, Acyclic ... Carboxylic Acids ... Amino Acids, Branched-Chain …
In eliciting its mechanism of action, sildenafil ultimately prevents or minimizes the breakdown of cyclic guanosine monophosphate (cGMP) by inhibiting cGMP specific phosphodiesterase type 5 (PDE5) [F3850, F3853, F3856, F3859, F3883, F3886, L5611, L5614]. The result of doing so allows cGMP present in both the penis and pulmonary vasculature to...
Approved
Investigational
Matched Description: … it to grow in size and become erect and rigid [F3850, F3853, F3856, F3859, F3883, F3886, L5611, L5614 ... The result of doing so allows cGMP present in both the penis and pulmonary vasculature to elicit smooth ... and the increased flow of blood into the spongy erectile tissue of the penis that consequently allows …
Matched Salts name: … Sildenafil citrate
Matched Products: … Sildenafil Citrate ... SILDENAFIL CITRATE ... sildenafil CITRATE
Hemoglobin in which the alpha-subunit are cross-linked intramolecularly.
Experimental
Matched Synonyms: … acid ... Hemoglobin A0 (human alpha2 beta2 tetrameric subunit), alpha-chain 99,99'-diamide with (E)-2-butenoic …
Matched Description: … Hemoglobin in which the alpha-subunit are cross-linked intramolecularly. …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Blood and Related Products ... Blood Substitutes and Perfusion Solutions ... Blood Substitutes and Plasma Protein Fractions …
Hydroxyamphetamine is a derivative of amphetamines. Hydroxyamphetamine is intended mainly as local eye drops for diagnostic purposes. It is indirect sympathomimetic agent which cause dilation of the eye pupil before diagnostic test. Among the minor side effects from its use are: change in color vision, difficulty seeing at night, dry...
Approved
Matched Synonyms: … dl-4-hydroxyamphetamine ... dl-p-hydroxyamphetamine …
Matched Description: … night, dry mouth, headache, increased sensitivity of eyes to sunlight, muscle stiffness or tightness and
Gadobenic acid, usually available in the salt form gadobenate dimeglumine, is a linear MRI gadolinium-based contrast agent (GBCA) used primarily for MR imaging of the liver. It differs from other GBCAs due to the benzene ring that confers weak protein binding, thus leading to an increased R1 and R2 relaxivity....
Approved
Investigational
Matched Synonyms: … Gadobenic acid ... Acide gadobenique ... Acido gadobenico …
Matched Name: … Gadobenic acid
Matched Description: … other GBCAs due to the benzene ring that confers weak protein binding, thus leading to an increased R1 and ... [A263166] As gadobenate dimeglumine is specifically taken up by hepatocytes and excreted through the ... Gadobenic acid, usually available in the salt form gadobenate dimeglumine, is a linear MRI gadolinium-based …
Matched Categories: … gadobenic acid
Baclofen is a gamma-aminobutyric acid (GABA) agonist used as a skeletal muscle relaxant. Although originally designed in 1962 to treat epilepsy, baclofen was not effective in treating this condition but instead was shown to reduce spasticity in selected patients. Baclofen was reintroduced in 1971 as a treatment for spasticity and...
Approved
Matched Synonyms: … DL-4-Amino-3-p-chlorophenylbutanoic acid ... DL-Baclofen ... 4-Amino-3-(4-chlorophenyl)butyric acid
Matched Iupac: … 4-amino-3-(4-chlorophenyl)butanoic acid
Matched Description: … [A245338] Baclofen was reintroduced in 1971 as a treatment for spasticity and was later approved by the ... used to manage severe muscle spasms of cerebral or spinal cord origins, including multiple sclerosis and ... [L39429] Baclofen was investigated for use in alcohol dependence and withdrawal; however, evidence …
Matched Salts name: … Baclofen hydrochloride
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... gamma-Aminobutyric Acid-ergic Agonist …
Levothyroxine is a synthetically produced form of thyroxine, a major endogenous hormone secreted by the thyroid gland. Also known as L-thyroxine or the brand name product Synthroid, levothyroxine is used primarily to treat hypothyroidism, a condition where the thyroid gland is no longer able to produce sufficient quantities of the...
Approved
Matched Iupac: … (2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoic acid
Matched Description: … produce sufficient quantities of the thyroid hormones T4 (tetraiodothyronine or thyroxine) and ... hypothyroidism begin to develop such as fatigue, increased heart rate, depression[A179620], dry skin and ... hair, muscle cramps, constipation, weight gain, memory impairment, and poor tolerance to cold temperatures …
Matched Mixtures name: … Levothyroxine and Liothyronine Thyroid ... Levothyroxine and Liothyronine Thyroid ... Levothyroxine and Liothyronine Thyroid …
Matched Salts name: … Levothyroxine sodium ... Levothyroxine sodium pentahydrate …
Matched Categories: … levothyroxine sodium and iodine compounds ... Amino Acids, Peptides, and Proteins ... Sex Hormones and Insulins ... levothyroxine sodium ... Hormones, Hormone Substitutes, and Hormone Antagonists …
Matched Products: … Levothyroxine Sodium ... Levothyroxine sodium ... Levothroxine Sodium
Buthionine sulfoximine has been used in trials studying the treatment of Neuroblastoma and Melanoma (Skin).
Investigational
Matched Synonyms: … DL-buthionine-(S,R)-sulfoximine ... Butanoic acid, 2-amino-4-(S-butylsulfonimidoyl)- …
Matched Iupac: … 2-amino-4-[butyl(imino)oxo-lambda6-sulfanyl]butanoic acid
Matched Description: … Buthionine sulfoximine has been used in trials studying the treatment of Neuroblastoma and Melanoma ( …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Sulfur …
Parnaparin is an heparin of low molecular weight with antithrombotic effects.
Approved
Investigational
Matched Synonyms: … Parnaparin sodium
Matched Categories: … Blood and Blood Forming Organs ... Heparin and similars …
Vet approved
Matched Synonyms: … dl-Pimobendan …
Esmolol, commonly marketed under the trade name Brevibloc, is a cardioselective beta-1 receptor blocker. It has a rapid onset but short duration of action without causing significant intrinsic sympathomimetic or membrane stabilizing activities at recommended therapeutic doses. It works by blocking beta-adrenergic receptors in the heart, which leads to decreased...
Approved
Withdrawn
Matched Synonyms: … 3-[4-(2-Hydroxy-3-isopropylamino-propoxy)-phenyl]-propionic acid methyl ester …
Matched Description: … It works by blocking beta-adrenergic receptors in the heart, which leads to decreased force and rate ... Esmolol prevents the action of two naturally occurring substances: epinephrine and norepinephrine. ... FDA withdrew its approval for the use of all parenteral dosage form drug products containing esmolol hydrochloride
Matched Salts name: … Esmolol hydrochloride
Matched Products: … Esmolol Hydrochloride In Sodium Chloride ... Esmolol Hydrochloride ... Esmolol Hydrochloride in Water …
Atropine is an alkaloid originally synthesized from Atropa belladonna. It is a racemic mixture of d-and l-hyoscyamine, of which only l-hyoscyamine is pharmacologically active.[A251670,L42835] Atropine is generally available as a sulfate salt and can be administered by intravenous, subcutaneous, intramuscular, intraosseous, endotracheal and ophthalmic methods. Oral atropine is only available...
Approved
Vet approved
Matched Synonyms: … dl-Hyoscyamine ... dl-tropyltropate …
Matched Description: … , subcutaneous, intramuscular, intraosseous, endotracheal and ophthalmic methods. ... It is a racemic mixture of d-and l-hyoscyamine, of which only l-hyoscyamine is pharmacologically active ... [A251670,L42835] Atropine is generally available as a sulfate salt and can be administered by intravenous …
Matched Mixtures name: … Diphenoxylate Hydrochloride and Atropine Sulfate ... Diphenoxylate Hydrochloride and Atropine Sulfate ... Diphenoxylate Hydrochloride and Atropine Sulfate …
Matched Salts name: … Atropine hydrochloride
Matched Categories: … Alimentary Tract and Metabolism ... Belladonna and Derivatives, Plain ... Mydriatics and Cycloplegics ... pralidoxime and atropine ... atropine and psycholeptics …
Alcohol use disorder is responsible for a large worldwide burden of morbidity, premature mortality, and economic consequences resulting from accidents, violence, incarceration, decreased productivity, and increased healthcare spending. Acamprosate, also known by the brand name Campral, is a drug used for the maintenance of alcohol abstinence. It is a structural...
Approved
Investigational
Matched Synonyms: … 3-Acetamido-1-propanesulfonic acid
Matched Iupac: … 3-acetamidopropane-1-sulfonic acid
Matched Description: … Alcohol use disorder is responsible for a large worldwide burden of morbidity, premature mortality, and ... economic consequences resulting from accidents, violence, incarceration, decreased productivity, and ... It was first approved by the FDA in 2004 and initially marketed by Forest Laboratories.[L31783] …
Matched Salts name: … Acamprosate calcium
Matched Categories: … Sulfur Acids ... Sulfonic Acids
Matched Products: … Acamprosate Calcium
Experimental
Matched Synonyms: … Pyridoxine 5-phosphate …
Matched Name: … Pyridoxine phosphate …
Matched Iupac: … {[5-hydroxy-4-(hydroxymethyl)-6-methylpyridin-3-yl]methoxy}phosphonic acid
Matched Categories: … Enzymes and Coenzymes …
Experimental
Matched Synonyms: … S-Methyl-alpha-ketobutyric acid ... alpha-Ketomethionine ... alpha-Keto-gamma-methiolbutyrate …
Matched Name: … 4-methylthio-2-oxobutanoic acid
Matched Iupac: … 4-(methylsulfanyl)-2-oxobutanoic acid
Matched Categories: … Amino Acids, Peptides, and Proteins ... Amino Acids ... Amino Acids, Neutral ... Amino Acids, Sulfur …
Experimental
Matched Name: … Chromic citrate
A phenothiazine used in the treatment of psychoses. Its properties and uses are generally similar to those of chlorpromazine.
Approved
Matched Description: … Its properties and uses are generally similar to those of chlorpromazine. …
Matched Salts name: … Fluphenazine hydrochloride
Matched Products: … Fluphenazine Hydrochloride ... Fluphenazine hydrochloride ... Fluphenazine Hydrochoride
Approved
Investigational
Matched Name: … Iron protein succinylate …
Matched Mixtures name: … KOMFER FOL 40 MG/185 MCG ORAL COZELTI, 10 FLK. ... KOMFER FOL 40 MG/185 MCG ORAL COZELTI, 20 FLK. ... FERPLEX FOL 40 MG + 0.185 MG/15 ML ORAL ÇÖZELTİ, 10 ADET …
Matched Categories: … Amino Acids, Peptides, and Proteins ... Blood and Blood Forming Organs ... Iron Preparations ... Iron Trivalent, Oral Preparations ... Acids, Acyclic …
Approved
Investigational
Matched Synonyms: … Medronic acid ... Acido medronico ... Acide medronique …
Matched Name: … Medronic acid
Matched Iupac: … (phosphonomethyl)phosphonic acid
Antibacterial obtained from Streptomyces orientalis. It is a glycopeptide related to ristocetin that inhibits bacterial cell wall assembly and is toxic to kidneys and the inner ear. As of January 29 2018, CutisPharma's Firvanq is the only FDA approved vancomycin oral liquid treatment option available for the the treatment of...
Approved
Matched Iupac: … }.0^{34,39}]pentaconta-3,5,8,10,12(48),14,16,29(45),30,32,34,36,38,46,49-pentadecaene-40-carboxylic acid
Matched Description: … kidneys and the inner ear. ... It is a glycopeptide related to ristocetin that inhibits bacterial cell wall assembly and is toxic to ... liquid treatment option available for the the treatment of _Clostridium difficile_ associated diarrhea and
Matched Mixtures name: … Vancomycin Hydrochloride ... Vancomycin Hydrochloride ... Vancomycin Hydrochloride
Matched Salts name: … Vancomycin hydrochloride
Matched Categories: … Amino Acids, Peptides, and Proteins ... Alimentary Tract and Metabolism …
Matched Products: … Vancomycin Injection USP In 0.9% Sodium Chloride ... Vancomycin Hydrochloride ... Vancomycin Hydrocloride
An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
Approved
Investigational
Nutraceutical
Matched Synonyms: … alpha-ketopropionic acid ... acide pyruvique ... 2-ketopropionic acid
Matched Name: … Pyruvic acid
Matched Iupac: … 2-oxopropanoic acid
Matched Description: … An intermediate compound in the metabolism of carbohydrates, proteins, and fats. ... In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous …
Matched Salts name: … Calcium pyruvate ... Sodium pyruvate …
Matched Categories: … Keto Acids ... Carboxylic Acids
Approved
Investigational
Matched Categories: … Fatty Acids ... Acids, Acyclic ... Carboxylic Acids ... Fatty Acids, Volatile …
Matched Products: … ACID MANTLECREMA ... ACID MANTLE NLOCION ... ACID MANTLE N LOCION …
Omega-3-acid ethyl esters are prescription drugs that contain eicosapentaenoic acid-ethyl ester (EPA) and docosahexaenoic acid-ethyl ester (DHA) that are used in combination with changes in diet to lower triglyceride levels in adults with severe (≥ 500 mg/dL) hypertriglyceridemia[FDA Label] . Omega-3-acid ethyl esters are currently marketed in the US, EU,...
Approved
Investigational
Matched Synonyms: … Omega-3-acid ethyl esters ... Omega-3 fatty acid ethyl esters …
Matched Name: … Omega-3-acid ethyl esters …
Matched Description: … and docosahexaenoic acid-ethyl ester (DHA) that are used in combination with changes in diet to lower ... Omega-3-acid ethyl esters are currently marketed in the US, EU, and many other regions under the brand ... triglyceride levels in adults with severe (≥ 500 mg/dL) hypertriglyceridemia[FDA Label][A176687]. …
Matched Categories: … Diet, Food, and Nutrition ... Fatty Acids ... Fatty Acids, Omega-3 ... Fatty Acids, Unsaturated …
Matched Products: … Omega-3-acid Ethyl Esters ... Omega-3-Acid Ethyl Esters ... Omega-3-Acid Ethyl Ester …
Displaying drugs 601 - 625 of 3163 in total